Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo

Cancer Research

Volumn 62, Issue 3, 2002, Pages 625-631

  Leahy, Kathleen M ^a   Ornberg, Richard L ^a   Wang, Yu ^a   Zweifel, Ben S ^a   Koki, Alane T ^a   Masferrer, Jaime L ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; BASIC FIBROBLAST GROWTH FACTOR; BASIC FIBROBLAST GROWTH FACTOR 2; CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; FIBROBLAST GROWTH FACTOR 2; PROSTAGLANDIN E2; THROMBOXANE B2; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GRAFT; CANCER INHIBITION; CANCER MODEL; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; METASTASIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SLOW RELEASE FORMULATION; TUMOR CELL; TUMOR GROWTH; TUMOR VASCULARIZATION;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DIVISION; COLONIC NEOPLASMS; CORNEA; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; ENDOTHELIUM, VASCULAR; FIBROBLAST GROWTH FACTOR 2; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRAZOLES; RATS; SULFONAMIDES; THROMBOXANE B2; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0036468287     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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