메뉴 건너뛰기




Volumn 70, Issue 3, 2006, Pages 446-456

Prostanoid signal transduction and gene expression in the endothelium: Role in cardiovascular diseases

Author keywords

Angiogenesis; Atherosclerosis; Gene expression; Prostaglandins; Signal transduction

Indexed keywords

PROSTACYCLIN RECEPTOR; PROSTAGLANDIN D2; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN J2; PROSTANOID; PROSTANOID RECEPTOR; THROMBOXANE A2 RECEPTOR;

EID: 33747466079     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2005.12.020     Document Type: Review
Times cited : (89)

References (98)
  • 1
    • 3242761489 scopus 로고    scopus 로고
    • Physiology of the endothelium
    • Galley H.F., and Webster N.R. Physiology of the endothelium. Br J Anaesth 93 (2004) 105-113
    • (2004) Br J Anaesth , vol.93 , pp. 105-113
    • Galley, H.F.1    Webster, N.R.2
  • 2
    • 0029805961 scopus 로고    scopus 로고
    • Endothelial adhesion molecules in atherogenesis
    • Vadas M.A., and Gamble J.R. Endothelial adhesion molecules in atherogenesis. Circ Res 79 (1996) 1216-1217
    • (1996) Circ Res , vol.79 , pp. 1216-1217
    • Vadas, M.A.1    Gamble, J.R.2
  • 3
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 6 (2000) 389-395
    • (2000) Nat Med , vol.6 , pp. 389-395
    • Carmeliet, P.1
  • 4
    • 0035976575 scopus 로고    scopus 로고
    • Prostaglandins and leukotrienes: advances in eicosanoid biology
    • Funk C.D. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science 294 (2001) 1871-1875
    • (2001) Science , vol.294 , pp. 1871-1875
    • Funk, C.D.1
  • 5
    • 0034644737 scopus 로고    scopus 로고
    • Internalization and sequestration of the human prostacyclin receptor
    • Smyth E.M., Austin S.C., Reilly M.P., and FitzGerald G.A. Internalization and sequestration of the human prostacyclin receptor. J Biol Chem 275 (2000) 2037-2045
    • (2000) J Biol Chem , vol.275 , pp. 2037-2045
    • Smyth, E.M.1    Austin, S.C.2    Reilly, M.P.3    FitzGerald, G.A.4
  • 6
    • 0033605423 scopus 로고    scopus 로고
    • Internalization of the TXA2 receptor alpha and beta isoforms. Role of the differentially spliced COOH terminus in agonist-promoted receptor internalization
    • Parent J.L., Labrecque P., Orsini M., and Benovic J.L. Internalization of the TXA2 receptor alpha and beta isoforms. Role of the differentially spliced COOH terminus in agonist-promoted receptor internalization. J Biol Chem 274 (1999) 941-948
    • (1999) J Biol Chem , vol.274 , pp. 941-948
    • Parent, J.L.1    Labrecque, P.2    Orsini, M.3    Benovic, J.L.4
  • 7
    • 0034617213 scopus 로고    scopus 로고
    • The alpha, but not the beta, isoform of the human thromboxane A2 receptor is a target for prostacyclin-mediated desensitization
    • Walsh M.T., Foley J.F., and Kinsella J.P. The alpha, but not the beta, isoform of the human thromboxane A2 receptor is a target for prostacyclin-mediated desensitization. J Biol Chem 275 (2000) 20412-20423
    • (2000) J Biol Chem , vol.275 , pp. 20412-20423
    • Walsh, M.T.1    Foley, J.F.2    Kinsella, J.P.3
  • 8
    • 1842559912 scopus 로고    scopus 로고
    • Thromboxane A2 receptor agonists antagonize the proangiogenic effects of fibroblast growth factor-2: role of receptor internalization, thrombospondin-1, and alpha(v)beta3
    • Ashton A.W., Cheng Y., Helisch A., and Ware J.A. Thromboxane A2 receptor agonists antagonize the proangiogenic effects of fibroblast growth factor-2: role of receptor internalization, thrombospondin-1, and alpha(v)beta3. Circ Res 94 (2004) 735-742
    • (2004) Circ Res , vol.94 , pp. 735-742
    • Ashton, A.W.1    Cheng, Y.2    Helisch, A.3    Ware, J.A.4
  • 9
    • 0034721883 scopus 로고    scopus 로고
    • Reversal of angiogenesis in vitro, induction of apoptosis, and inhibition of AKT phosphorylation in endothelial cells by thromboxane A(2)
    • Gao Y., Yokota R., Tang S., Ashton A.W., and Ware J.A. Reversal of angiogenesis in vitro, induction of apoptosis, and inhibition of AKT phosphorylation in endothelial cells by thromboxane A(2). Circ Res 87 (2000) 739-745
    • (2000) Circ Res , vol.87 , pp. 739-745
    • Gao, Y.1    Yokota, R.2    Tang, S.3    Ashton, A.W.4    Ware, J.A.5
  • 10
    • 0028179510 scopus 로고
    • G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets
    • Offermanns S., Laugwitz K.L., Spicher K., and Schultz G. G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets. Proc Natl Acad Sci U S A 91 (1994) 504-508
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 504-508
    • Offermanns, S.1    Laugwitz, K.L.2    Spicher, K.3    Schultz, G.4
  • 12
    • 4143069201 scopus 로고    scopus 로고
    • Thromboxane A2 receptor signaling inhibits vascular endothelial growth factor-induced endothelial cell differentiation and migration
    • Ashton A.W., and Ware J.A. Thromboxane A2 receptor signaling inhibits vascular endothelial growth factor-induced endothelial cell differentiation and migration. Circ Res 95 (2004) 372-379
    • (2004) Circ Res , vol.95 , pp. 372-379
    • Ashton, A.W.1    Ware, J.A.2
  • 13
    • 0037195421 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes integrin alpha Vbeta 3-dependent endothelial cell adhesion, rac-activation, and spreading through cAMP/PKA-dependent signaling
    • Dormond O., Bezzi M., Mariotti A., and Ruegg C. Prostaglandin E2 promotes integrin alpha Vbeta 3-dependent endothelial cell adhesion, rac-activation, and spreading through cAMP/PKA-dependent signaling. J Biol Chem 277 (2002) 45838-45846
    • (2002) J Biol Chem , vol.277 , pp. 45838-45846
    • Dormond, O.1    Bezzi, M.2    Mariotti, A.3    Ruegg, C.4
  • 14
    • 0033024889 scopus 로고    scopus 로고
    • Localization of functional prostaglandin E2 receptors EP3 and EP4 in the nuclear envelope
    • Battacharya M., Peri K., Ribeiro-Da-Silva A., Almazan G., Shichi H., Hou X., et al. Localization of functional prostaglandin E2 receptors EP3 and EP4 in the nuclear envelope. J Biol Chem 274 (1999) 15719-15724
    • (1999) J Biol Chem , vol.274 , pp. 15719-15724
    • Battacharya, M.1    Peri, K.2    Ribeiro-Da-Silva, A.3    Almazan, G.4    Shichi, H.5    Hou, X.6
  • 15
    • 0027201851 scopus 로고
    • Cloning and expression of cDNA for a mouse EP1 subtype of prostaglandin E2 receptor
    • Watabe A., Sugimoto Y., Honda A., Irie A., Namba T., Negishi M., et al. Cloning and expression of cDNA for a mouse EP1 subtype of prostaglandin E2 receptor. J Biol Chem 268 (1993) 20175-20178
    • (1993) J Biol Chem , vol.268 , pp. 20175-20178
    • Watabe, A.1    Sugimoto, Y.2    Honda, A.3    Irie, A.4    Namba, T.5    Negishi, M.6
  • 17
    • 0344153852 scopus 로고    scopus 로고
    • Cyclooxygenase-2-derived E prostaglandins down-regulate matrix metalloproteinase-1 expression in fibroblast-like synoviocytes via inhibition of extracellular signal-regulated kinase activation
    • Pillinger M.H., Rosenthal P.B., Tolani S.N., Apsel B., Dinsell V., Greenberg J., et al. Cyclooxygenase-2-derived E prostaglandins down-regulate matrix metalloproteinase-1 expression in fibroblast-like synoviocytes via inhibition of extracellular signal-regulated kinase activation. J Immunol 171 (2003) 6080-6089
    • (2003) J Immunol , vol.171 , pp. 6080-6089
    • Pillinger, M.H.1    Rosenthal, P.B.2    Tolani, S.N.3    Apsel, B.4    Dinsell, V.5    Greenberg, J.6
  • 18
    • 0037169557 scopus 로고    scopus 로고
    • Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2
    • Fujino H., West K.A., and Regan J.W. Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2. J Biol Chem 277 (2002) 2614-2619
    • (2002) J Biol Chem , vol.277 , pp. 2614-2619
    • Fujino, H.1    West, K.A.2    Regan, J.W.3
  • 19
    • 0037809229 scopus 로고    scopus 로고
    • Prostaglandin E2 induced functional expression of early growth response factor-1 by EP4, but not EP2, prostanoid receptors via the phosphatidylinositol 3-kinase and extracellular signal-regulated kinases
    • Fujino H., Xu W., and Regan J.W. Prostaglandin E2 induced functional expression of early growth response factor-1 by EP4, but not EP2, prostanoid receptors via the phosphatidylinositol 3-kinase and extracellular signal-regulated kinases. J Biol Chem 278 (2003) 12151-12156
    • (2003) J Biol Chem , vol.278 , pp. 12151-12156
    • Fujino, H.1    Xu, W.2    Regan, J.W.3
  • 20
    • 0032823306 scopus 로고    scopus 로고
    • Prostanoid receptors: structures, properties, and functions
    • Narumiya S., Sugimoto Y., and Ushikubi F. Prostanoid receptors: structures, properties, and functions. Physiol Rev 79 (1999) 1193-1226
    • (1999) Physiol Rev , vol.79 , pp. 1193-1226
    • Narumiya, S.1    Sugimoto, Y.2    Ushikubi, F.3
  • 21
    • 0029056741 scopus 로고
    • Activation of mitogen-activated protein kinase by the human prostaglandin EP3A receptor
    • Burkey T.H., and Regan J.W. Activation of mitogen-activated protein kinase by the human prostaglandin EP3A receptor. Biochem Biophys Res Commun 211 (1995) 152-158
    • (1995) Biochem Biophys Res Commun , vol.211 , pp. 152-158
    • Burkey, T.H.1    Regan, J.W.2
  • 22
    • 4344578831 scopus 로고    scopus 로고
    • Prostaglandin E2 activates Src signaling in lung adenocarcinoma cell via EP3
    • Yamaki T., Endoh K., Miyahara M., Nagamine I., Huong N., Sakurai H., et al. Prostaglandin E2 activates Src signaling in lung adenocarcinoma cell via EP3. Cancer Lett 214 (2004) 115-120
    • (2004) Cancer Lett , vol.214 , pp. 115-120
    • Yamaki, T.1    Endoh, K.2    Miyahara, M.3    Nagamine, I.4    Huong, N.5    Sakurai, H.6
  • 23
    • 0036594073 scopus 로고    scopus 로고
    • Prostaglandin receptors: advances in the study of EP3 receptor signaling
    • Hatae N., Sugimoto Y., and Ichikawa A. Prostaglandin receptors: advances in the study of EP3 receptor signaling. J Biochem (Tokyo) 131 (2002) 781-784
    • (2002) J Biochem (Tokyo) , vol.131 , pp. 781-784
    • Hatae, N.1    Sugimoto, Y.2    Ichikawa, A.3
  • 24
    • 0035943611 scopus 로고    scopus 로고
    • Prostaglandin E(2) regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1 beta-treated human synovial fibroblasts
    • Faour W.H., He Y., He Q.W., De Ladurantaye M., Quintero M., Mancini A., et al. Prostaglandin E(2) regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1 beta-treated human synovial fibroblasts. J Biol Chem 276 (2001) 31720-31731
    • (2001) J Biol Chem , vol.276 , pp. 31720-31731
    • Faour, W.H.1    He, Y.2    He, Q.W.3    De Ladurantaye, M.4    Quintero, M.5    Mancini, A.6
  • 26
    • 0036135613 scopus 로고    scopus 로고
    • Prostaglandin E(2)-mediated activation of HIV-1 long terminal repeat transcription in human T cells necessitates CCAAT/enhancer binding protein (C/EBP) binding sites in addition to cooperative interactions between C/EBPbeta and cyclic adenosine 5′-monophosphate response element binding protein
    • Dumais N., Bounou S., Olivier M., and Tremblay M. Prostaglandin E(2)-mediated activation of HIV-1 long terminal repeat transcription in human T cells necessitates CCAAT/enhancer binding protein (C/EBP) binding sites in addition to cooperative interactions between C/EBPbeta and cyclic adenosine 5′-monophosphate response element binding protein. J Immunol 168 (2002) 274-282
    • (2002) J Immunol , vol.168 , pp. 274-282
    • Dumais, N.1    Bounou, S.2    Olivier, M.3    Tremblay, M.4
  • 27
    • 0037146555 scopus 로고    scopus 로고
    • Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line
    • Liu X.H., Kirschenbaum A., Lu M., Yao S., Dosoretz A., Holland J.F., et al. Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line. J Biol Chem 277 (2002) 50081-50086
    • (2002) J Biol Chem , vol.277 , pp. 50081-50086
    • Liu, X.H.1    Kirschenbaum, A.2    Lu, M.3    Yao, S.4    Dosoretz, A.5    Holland, J.F.6
  • 28
    • 0041816104 scopus 로고    scopus 로고
    • Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor
    • Buchanan F.G., Wang D., Bargiacchi F., and DuBois R.N. Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor. J Biol Chem 278 (2003) 35451-35457
    • (2003) J Biol Chem , vol.278 , pp. 35451-35457
    • Buchanan, F.G.1    Wang, D.2    Bargiacchi, F.3    DuBois, R.N.4
  • 29
    • 0036006453 scopus 로고    scopus 로고
    • Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy
    • Pai R., Soreghan B.A., Szabo I.L., Pavelka M., Baatar D., and Tarnawski A.S. Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy. Nat Med 8 (2002) 289-293
    • (2002) Nat Med , vol.8 , pp. 289-293
    • Pai, R.1    Soreghan, B.A.2    Szabo, I.L.3    Pavelka, M.4    Baatar, D.5    Tarnawski, A.S.6
  • 30
    • 4544320012 scopus 로고    scopus 로고
    • Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta
    • Wang D., Wang H., Shi Q., Katkuri S., Walhi W., Desvergne B., et al. Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta. Cancer Cell 6 (2004) 285-295
    • (2004) Cancer Cell , vol.6 , pp. 285-295
    • Wang, D.1    Wang, H.2    Shi, Q.3    Katkuri, S.4    Walhi, W.5    Desvergne, B.6
  • 31
    • 0033664001 scopus 로고    scopus 로고
    • Comparison of agonist-induced internalization of the human EP2 and EP4 prostaglandin receptors: role of the carboxyl terminus in EP4 receptor sequestration
    • Desai S., April H., Nwaneshiudu C., and Ashby B. Comparison of agonist-induced internalization of the human EP2 and EP4 prostaglandin receptors: role of the carboxyl terminus in EP4 receptor sequestration. Mol Pharmacol 58 (2000) 1279-1286
    • (2000) Mol Pharmacol , vol.58 , pp. 1279-1286
    • Desai, S.1    April, H.2    Nwaneshiudu, C.3    Ashby, B.4
  • 33
    • 0028839874 scopus 로고
    • Activation of thromboxane and prostacyclin receptors elicits opposing effects on vascular smooth muscle cell growth and mitogen-activated protein kinase signaling cascades
    • Jones D.A., Benjamin C.W., and Linseman D.A. Activation of thromboxane and prostacyclin receptors elicits opposing effects on vascular smooth muscle cell growth and mitogen-activated protein kinase signaling cascades. Mol Pharmacol 48 (1995) 890-896
    • (1995) Mol Pharmacol , vol.48 , pp. 890-896
    • Jones, D.A.1    Benjamin, C.W.2    Linseman, D.A.3
  • 34
    • 0030952937 scopus 로고    scopus 로고
    • Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
    • Forman B.M., Chen J., and Evans R.M. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci USA 94 (1997) 4312-4317
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4312-4317
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 36
    • 0042808525 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and the cardiovascular system
    • Chen Y.E., Fu M., Zhang J., Zhu X., Lin Y., Akinbami M.A., et al. Peroxisome proliferator-activated receptors and the cardiovascular system. Vitam Horm 66 (2003) 157-188
    • (2003) Vitam Horm , vol.66 , pp. 157-188
    • Chen, Y.E.1    Fu, M.2    Zhang, J.3    Zhu, X.4    Lin, Y.5    Akinbami, M.A.6
  • 37
    • 0034993832 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: from transcriptional control to clinical practice
    • Pineda I., Chinetti G., Duval C., Fruchart J.C., and Staels B. Peroxisome proliferator-activated receptors: from transcriptional control to clinical practice. Curr Opin Lipidol 12 (2001) 245-254
    • (2001) Curr Opin Lipidol , vol.12 , pp. 245-254
    • Pineda, I.1    Chinetti, G.2    Duval, C.3    Fruchart, J.C.4    Staels, B.5
  • 38
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M., Li A.C., Wilson T.M., Kelly C.J., and Glass C.K. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 391 (1998) 79-82
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Wilson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 39
    • 3442878955 scopus 로고    scopus 로고
    • Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-gamma-independent mechanism
    • Grau R., Iniguez M.A., and Fresno M. Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-gamma-independent mechanism. Cancer Res 64 (2004) 5162-5171
    • (2004) Cancer Res , vol.64 , pp. 5162-5171
    • Grau, R.1    Iniguez, M.A.2    Fresno, M.3
  • 41
    • 0037315485 scopus 로고    scopus 로고
    • Potentiation of protein kinase C zeta activity by 15-deoxy-delta(12,14)-prostaglandin J(2) induces an imbalance between mitogen-activated protein kinases and NF-kappa B that promotes apoptosis in macrophages
    • Castrillo A., Través P., Martín-Sanz P., Parkinson S.J., Parker P.J., and Bosca L. Potentiation of protein kinase C zeta activity by 15-deoxy-delta(12,14)-prostaglandin J(2) induces an imbalance between mitogen-activated protein kinases and NF-kappa B that promotes apoptosis in macrophages. Mol Cell Biol 23 (2003) 1196-1208
    • (2003) Mol Cell Biol , vol.23 , pp. 1196-1208
    • Castrillo, A.1    Través, P.2    Martín-Sanz, P.3    Parkinson, S.J.4    Parker, P.J.5    Bosca, L.6
  • 42
    • 0347362832 scopus 로고    scopus 로고
    • 15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase 1 activity induced by lipopolysaccharide
    • Caivano M., Rodriguez C., Cohen P., and Alemany S. 15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase 1 activity induced by lipopolysaccharide. J Biol Chem 278 (2003) 52124-52130
    • (2003) J Biol Chem , vol.278 , pp. 52124-52130
    • Caivano, M.1    Rodriguez, C.2    Cohen, P.3    Alemany, S.4
  • 43
    • 85047676780 scopus 로고    scopus 로고
    • Prostaglandin F2alpha stimulates the Raf/MEK1/mitogen-activated protein kinase signaling cascade in bovine luteal cells
    • Chen D.B., Westfall S.D., Fong H., Roberson M.S., and Davis J.S. Prostaglandin F2alpha stimulates the Raf/MEK1/mitogen-activated protein kinase signaling cascade in bovine luteal cells. Endocrinology 139 (1998) 3876-3885
    • (1998) Endocrinology , vol.139 , pp. 3876-3885
    • Chen, D.B.1    Westfall, S.D.2    Fong, H.3    Roberson, M.S.4    Davis, J.S.5
  • 44
    • 0037437175 scopus 로고    scopus 로고
    • Prostaglandin F alpha stimulates growth of skeletal muscle cells via an NFATC2-dependent pathway
    • Horsley V., and Pavlath G.K. Prostaglandin F alpha stimulates growth of skeletal muscle cells via an NFATC2-dependent pathway. J Cell Biol 161 (2003) 111-118
    • (2003) J Cell Biol , vol.161 , pp. 111-118
    • Horsley, V.1    Pavlath, G.K.2
  • 45
    • 8544247154 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinase pathway in prostaglandin F2alpha-induced rat puerperal uterine contraction
    • Ohmichi M., Koike K., Kimura A., Masuhara K., Ikegami H., Ikebuchi Y., et al. Role of mitogen-activated protein kinase pathway in prostaglandin F2alpha-induced rat puerperal uterine contraction. Endocrinology 138 (1997) 3103-3111
    • (1997) Endocrinology , vol.138 , pp. 3103-3111
    • Ohmichi, M.1    Koike, K.2    Kimura, A.3    Masuhara, K.4    Ikegami, H.5    Ikebuchi, Y.6
  • 46
    • 0033544916 scopus 로고    scopus 로고
    • Activation of FP prostanoid receptor isoforms leads to Rho-mediated changes in cell morphology and in the cell cytoskeleton
    • Pierce K.L., Fujino H., Srinivasan D., and Regan J.W. Activation of FP prostanoid receptor isoforms leads to Rho-mediated changes in cell morphology and in the cell cytoskeleton. J Biol Chem 274 (1999) 35944-35949
    • (1999) J Biol Chem , vol.274 , pp. 35944-35949
    • Pierce, K.L.1    Fujino, H.2    Srinivasan, D.3    Regan, J.W.4
  • 47
    • 0035918222 scopus 로고    scopus 로고
    • FP prostanoid receptor activation of a T-cell factor/beta-catenin signaling pathway
    • Fujino H., and Regan J.W. FP prostanoid receptor activation of a T-cell factor/beta-catenin signaling pathway. J Biol Chem 276 (2001) 12489-12492
    • (2001) J Biol Chem , vol.276 , pp. 12489-12492
    • Fujino, H.1    Regan, J.W.2
  • 48
  • 49
  • 50
    • 0036015979 scopus 로고    scopus 로고
    • Induction of cyclooxygenase-2 and enhanced release of prostaglandin E(2) and I(2) in human endothelial cells by engagement of CD40
    • Garlichs C.D., Geis T., Goppelt-Struebe M., Eskafi S., Schmidt A., Schulze-Koops H., et al. Induction of cyclooxygenase-2 and enhanced release of prostaglandin E(2) and I(2) in human endothelial cells by engagement of CD40. Atherosclerosis 163 (2002) 9-16
    • (2002) Atherosclerosis , vol.163 , pp. 9-16
    • Garlichs, C.D.1    Geis, T.2    Goppelt-Struebe, M.3    Eskafi, S.4    Schmidt, A.5    Schulze-Koops, H.6
  • 51
    • 0033000419 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein suppresses expression of inducible cyclooxygenase in human macrophages
    • Eligini S., Colli S., Basso F., Sironi L., and Tremoli E. Oxidized low density lipoprotein suppresses expression of inducible cyclooxygenase in human macrophages. Arterioscler Thromb Vasc Biol 19 (1999) 1719-1725
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1719-1725
    • Eligini, S.1    Colli, S.2    Basso, F.3    Sironi, L.4    Tremoli, E.5
  • 52
    • 1842453964 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and inflammation in atherosclerosis
    • Linton M.F., and Fazio S. Cyclooxygenase-2 and inflammation in atherosclerosis. Curr Opin Pharmacol 4 (2004) 116-123
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 116-123
    • Linton, M.F.1    Fazio, S.2
  • 53
    • 0037117652 scopus 로고    scopus 로고
    • Cyclooxygenase-2 promotes early atherosclerotic formation in LDL receptor-deficient mice
    • Burleigh M.E., Babaev V.R., Oates J.A., Harris R.C., Gautam S., Riendeau D., et al. Cyclooxygenase-2 promotes early atherosclerotic formation in LDL receptor-deficient mice. Circulation 105 (2002) 1816-1823
    • (2002) Circulation , vol.105 , pp. 1816-1823
    • Burleigh, M.E.1    Babaev, V.R.2    Oates, J.A.3    Harris, R.C.4    Gautam, S.5    Riendeau, D.6
  • 55
    • 0035010184 scopus 로고    scopus 로고
    • A major role for VCAM-1, but not ICAM-1, in early atherosclerosis
    • Cybulsky M., Iiyama K., Li H., Zhu S., Chen M., Iiyama M., et al. A major role for VCAM-1, but not ICAM-1, in early atherosclerosis. J Clin Invest 107 (2001) 1255-1262
    • (2001) J Clin Invest , vol.107 , pp. 1255-1262
    • Cybulsky, M.1    Iiyama, K.2    Li, H.3    Zhu, S.4    Chen, M.5    Iiyama, M.6
  • 56
    • 0034598336 scopus 로고    scopus 로고
    • P-Selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E-deficient mice
    • Collins R.G., Velji R., Guevara N.V., Hicks M.J., Chan L., and Beaudet A.L. P-Selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E-deficient mice. J Exp Med 191 (2000) 189-194
    • (2000) J Exp Med , vol.191 , pp. 189-194
    • Collins, R.G.1    Velji, R.2    Guevara, N.V.3    Hicks, M.J.4    Chan, L.5    Beaudet, A.L.6
  • 57
    • 0032134003 scopus 로고    scopus 로고
    • Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein-deficient mice
    • Gu L., Okada Y., Clinton S.K., Gerard C., Sukhova G.K., Libby P., et al. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein-deficient mice. Mol Cell 2 (1998) 275-281
    • (1998) Mol Cell , vol.2 , pp. 275-281
    • Gu, L.1    Okada, Y.2    Clinton, S.K.3    Gerard, C.4    Sukhova, G.K.5    Libby, P.6
  • 58
    • 0034726705 scopus 로고    scopus 로고
    • Repression of TNF-alpha-induced E-selectin expression by PPAR activators: involvement of transcriptional repressor LRF-1/ATF3
    • Nawa T., Nawa M.T., Cai Y., Zhang C., Uchimura I., Narumi S., et al. Repression of TNF-alpha-induced E-selectin expression by PPAR activators: involvement of transcriptional repressor LRF-1/ATF3. Biochem Biophys Res Commun 275 (2000) 406-411
    • (2000) Biochem Biophys Res Commun , vol.275 , pp. 406-411
    • Nawa, T.1    Nawa, M.T.2    Cai, Y.3    Zhang, C.4    Uchimura, I.5    Narumi, S.6
  • 59
    • 0034805606 scopus 로고    scopus 로고
    • Dual function of troglitazone in ICAM-1 gene expression in human vascular endothelium
    • Chen N.G., and Han X. Dual function of troglitazone in ICAM-1 gene expression in human vascular endothelium. Biochem Biophys Res Commun 282 (2001) 717-722
    • (2001) Biochem Biophys Res Commun , vol.282 , pp. 717-722
    • Chen, N.G.1    Han, X.2
  • 60
    • 2942670612 scopus 로고    scopus 로고
    • PPARgamma agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway: role of diacylglycerol kinase
    • Verrier E., Wang L., Wadham C., Albanese N., Hahn C., Gamble J.R., et al. PPARgamma agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway: role of diacylglycerol kinase. Circ Res 94 (2004) 1515-1522
    • (2004) Circ Res , vol.94 , pp. 1515-1522
    • Verrier, E.1    Wang, L.2    Wadham, C.3    Albanese, N.4    Hahn, C.5    Gamble, J.R.6
  • 61
    • 16244399864 scopus 로고    scopus 로고
    • 15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) signals through retinoic acid receptor-related orphan receptor-alpha but not peroxisome proliferator-activated receptor-gamma in human vascular endothelial cells: the effect of 15d-PGJ2 on tumor necrosis factor-alpha-induced gene expression
    • Migita H., and Morser J. 15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) signals through retinoic acid receptor-related orphan receptor-alpha but not peroxisome proliferator-activated receptor-gamma in human vascular endothelial cells: the effect of 15d-PGJ2 on tumor necrosis factor-alpha-induced gene expression. Arterioscler Thromb Vasc Biol 25 (2005) 710-716
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 710-716
    • Migita, H.1    Morser, J.2
  • 62
    • 0037302090 scopus 로고    scopus 로고
    • Effects of the prostaglandin I2 analogue, beraprost sodium, on vascular cell adhesion molecule-1 expression in human vascular endothelial cells and circulating vascular cell adhesion molecule-1 level in patients with type 2 diabetes mellitus
    • Goya K., Otsuki M., Xu X., and Kasayama S. Effects of the prostaglandin I2 analogue, beraprost sodium, on vascular cell adhesion molecule-1 expression in human vascular endothelial cells and circulating vascular cell adhesion molecule-1 level in patients with type 2 diabetes mellitus. Metabolism 52 (2003) 192-198
    • (2003) Metabolism , vol.52 , pp. 192-198
    • Goya, K.1    Otsuki, M.2    Xu, X.3    Kasayama, S.4
  • 63
    • 0037168869 scopus 로고    scopus 로고
    • PPARalpha and PPARdelta activators inhibit cytokine-induced nuclear translocation of NF-kappaB and expression of VCAM-1 in EAhy926 endothelial cells
    • Rival Y., Beneteau N., Taillandier T., Pezet M., Dupont-Passelaigue E., Patoiseau J.F., et al. PPARalpha and PPARdelta activators inhibit cytokine-induced nuclear translocation of NF-kappaB and expression of VCAM-1 in EAhy926 endothelial cells. Eur J Pharmacol 435 (2002) 143-151
    • (2002) Eur J Pharmacol , vol.435 , pp. 143-151
    • Rival, Y.1    Beneteau, N.2    Taillandier, T.3    Pezet, M.4    Dupont-Passelaigue, E.5    Patoiseau, J.F.6
  • 64
    • 0036402996 scopus 로고    scopus 로고
    • 15-Deoxy-prostaglandin J(2) inhibits PDGF-A and -B chain expression in human vascular endothelial cells independent of PPAR gamma
    • Zhang J., Fu M., Zhao L., and Chen Y.E. 15-Deoxy-prostaglandin J(2) inhibits PDGF-A and -B chain expression in human vascular endothelial cells independent of PPAR gamma. Biochem Biophys Res Commun 298 (2002) 128-132
    • (2002) Biochem Biophys Res Commun , vol.298 , pp. 128-132
    • Zhang, J.1    Fu, M.2    Zhao, L.3    Chen, Y.E.4
  • 65
    • 0034660182 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma activators inhibit IFN-gamma-induced expression of the T cell-active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells
    • Marx N., Mach F., Sauty A., Leung J.H., Sarafi M.N., Ransohoff R.M., et al. Peroxisome proliferator-activated receptor-gamma activators inhibit IFN-gamma-induced expression of the T cell-active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells. J Immunol 164 (2000) 6503-6508
    • (2000) J Immunol , vol.164 , pp. 6503-6508
    • Marx, N.1    Mach, F.2    Sauty, A.3    Leung, J.H.4    Sarafi, M.N.5    Ransohoff, R.M.6
  • 66
    • 0037154549 scopus 로고    scopus 로고
    • PPARgamma but not PPARalpha ligands are potent repressors of major histocompatibility complex class II induction in atheroma-associated cells
    • Kwak B.R., Myit S., Mulhaupt F., Veillard N., Rufer N., Roosnek E., et al. PPARgamma but not PPARalpha ligands are potent repressors of major histocompatibility complex class II induction in atheroma-associated cells. Circ Res 90 (2002) 356-362
    • (2002) Circ Res , vol.90 , pp. 356-362
    • Kwak, B.R.1    Myit, S.2    Mulhaupt, F.3    Veillard, N.4    Rufer, N.5    Roosnek, E.6
  • 67
    • 0036714972 scopus 로고    scopus 로고
    • 15-deoxy-delta12,14-Prostaglandin J2 inhibits tissue factor expression in human macrophages and endothelial cells: evidence for ERK1/2 signaling pathway blockade
    • Eligini S., Banfi C., Brambilla M., Camera M., Barbieri S.S., Poma F., et al. 15-deoxy-delta12,14-Prostaglandin J2 inhibits tissue factor expression in human macrophages and endothelial cells: evidence for ERK1/2 signaling pathway blockade. Thromb Haemost 88 (2002) 524-532
    • (2002) Thromb Haemost , vol.88 , pp. 524-532
    • Eligini, S.1    Banfi, C.2    Brambilla, M.3    Camera, M.4    Barbieri, S.S.5    Poma, F.6
  • 68
    • 0036121601 scopus 로고    scopus 로고
    • 15 deoxy delta12,14 PGJ2 induces procoagulant activity in cultured human endothelial cells
    • Xie S., O'Regan D.J., Kakkar V.V., and Scully M.F. 15 deoxy delta12,14 PGJ2 induces procoagulant activity in cultured human endothelial cells. Thromb Haemost 87 (2002) 523-529
    • (2002) Thromb Haemost , vol.87 , pp. 523-529
    • Xie, S.1    O'Regan, D.J.2    Kakkar, V.V.3    Scully, M.F.4
  • 69
    • 0032587328 scopus 로고    scopus 로고
    • PPARgamma activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression: PPARgamma as a potential mediator in vascular disease
    • Marx N., Bourcier T., Sukhova G.K., Libby P., and Plutzky J. PPARgamma activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression: PPARgamma as a potential mediator in vascular disease. Arterioscler Thromb Vasc Biol 19 (1999) 546-551
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 546-551
    • Marx, N.1    Bourcier, T.2    Sukhova, G.K.3    Libby, P.4    Plutzky, J.5
  • 70
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis: the road ahead
    • Glass C.K., and Witztum J.L. Atherosclerosis: the road ahead. Cell (2001) 503-516
    • (2001) Cell , pp. 503-516
    • Glass, C.K.1    Witztum, J.L.2
  • 71
    • 0035928784 scopus 로고    scopus 로고
    • Overexpression of functionally coupled cyclooxygenase-2 and prostaglandin E synthase in symptomatic atherosclerotic plaques as a basis of prostaglandin E2-dependent plaque instability
    • Cipollone F., Prontera C., Pini B., Marini M., Fazia M., De Cesare D., et al. Overexpression of functionally coupled cyclooxygenase-2 and prostaglandin E synthase in symptomatic atherosclerotic plaques as a basis of prostaglandin E2-dependent plaque instability. Circulation 104 (2001) 921-927
    • (2001) Circulation , vol.104 , pp. 921-927
    • Cipollone, F.1    Prontera, C.2    Pini, B.3    Marini, M.4    Fazia, M.5    De Cesare, D.6
  • 72
    • 12144289317 scopus 로고    scopus 로고
    • Blockade of the angiotensin II type 1 receptor stabilizes atherosclerotic plaques in humans by inhibiting prostaglandin E2-dependent matrix metalloprotease activity
    • Cipollone F., Fazia M., Iezzi A., Pini B., Cuccurullo C., Zucchelli G.C., et al. Blockade of the angiotensin II type 1 receptor stabilizes atherosclerotic plaques in humans by inhibiting prostaglandin E2-dependent matrix metalloprotease activity. Circulation 109 (2004) 1482-1488
    • (2004) Circulation , vol.109 , pp. 1482-1488
    • Cipollone, F.1    Fazia, M.2    Iezzi, A.3    Pini, B.4    Cuccurullo, C.5    Zucchelli, G.C.6
  • 73
    • 0033528660 scopus 로고    scopus 로고
    • Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice
    • Moulton K.S., Heller E., Konerding M.A., Flynn E., Palinski W., and Folkman J. Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Circulation 99 (1999) 1726-1732
    • (1999) Circulation , vol.99 , pp. 1726-1732
    • Moulton, K.S.1    Heller, E.2    Konerding, M.A.3    Flynn, E.4    Palinski, W.5    Folkman, J.6
  • 74
    • 0033546190 scopus 로고    scopus 로고
    • Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2
    • Bishop-Bailey D., and Hla T. Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2. J Biol Chem 274 (1999) 17042-17048
    • (1999) J Biol Chem , vol.274 , pp. 17042-17048
    • Bishop-Bailey, D.1    Hla, T.2
  • 75
    • 0038001453 scopus 로고    scopus 로고
    • 15-deoxy-delta 12,14-prostaglandin J2 and laminar fluid shear stress stabilize c-IAP1 in vascular endothelial cells
    • Taba Y., Miyagi M., Miwa Y., Inoue H., Takahashi-Yanaga F., Morimoto S., et al. 15-deoxy-delta 12,14-prostaglandin J2 and laminar fluid shear stress stabilize c-IAP1 in vascular endothelial cells. Am J Physiol Heart Circ Physiol 285 (2003) H38-H46
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Taba, Y.1    Miyagi, M.2    Miwa, Y.3    Inoue, H.4    Takahashi-Yanaga, F.5    Morimoto, S.6
  • 76
    • 0036372456 scopus 로고    scopus 로고
    • Prostanoid signal integration and cross talk
    • Wise H., Wong Y.H., and Jones R.L. Prostanoid signal integration and cross talk. Neurosignals 11 (2002) 20-28
    • (2002) Neurosignals , vol.11 , pp. 20-28
    • Wise, H.1    Wong, Y.H.2    Jones, R.L.3
  • 77
    • 0029021148 scopus 로고
    • Hypertension in mice lacking the gene for endothelial nitric oxide synthase
    • Huang P.L., Huang Z., and Mashimo H. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 377 (1995) 239-242
    • (1995) Nature , vol.377 , pp. 239-242
    • Huang, P.L.1    Huang, Z.2    Mashimo, H.3
  • 78
    • 0030816051 scopus 로고    scopus 로고
    • Altered pain perception and inflammatory response in mice lacking prostacyclin receptor
    • Murata T., Ushikubi T., Matsuoka M., Hirata A., Yamasaki Y., Sugimoto A., et al. Altered pain perception and inflammatory response in mice lacking prostacyclin receptor. Nature 388 (1997) 678-682
    • (1997) Nature , vol.388 , pp. 678-682
    • Murata, T.1    Ushikubi, T.2    Matsuoka, M.3    Hirata, A.4    Yamasaki, Y.5    Sugimoto, A.6
  • 79
    • 0027161713 scopus 로고
    • Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension
    • Panza J.A., Casino P.R., Kilcoyne C.M., and Quyyumi A.A. Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension. Circulation 87 (1993) 1468-1474
    • (1993) Circulation , vol.87 , pp. 1468-1474
    • Panza, J.A.1    Casino, P.R.2    Kilcoyne, C.M.3    Quyyumi, A.A.4
  • 80
    • 24144448954 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms
    • Polikandriotis J.A., Mazzella L.J., Rupnow H.L., and Hart C.M. Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms. Arterioscler Thromb Vasc Biol 25 (2005) 1810-1816
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1810-1816
    • Polikandriotis, J.A.1    Mazzella, L.J.2    Rupnow, H.L.3    Hart, C.M.4
  • 82
  • 83
    • 0033520304 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway
    • Delerive P., Martin-Nizard F., Chinetti G., Trottein F., Fruchart J.C., Najib J., et al. Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway. Circ Res 85 (1999) 394-402
    • (1999) Circ Res , vol.85 , pp. 394-402
    • Delerive, P.1    Martin-Nizard, F.2    Chinetti, G.3    Trottein, F.4    Fruchart, J.C.5    Najib, J.6
  • 84
    • 0030115817 scopus 로고    scopus 로고
    • PGE2 and PGI2 inhibit ET-1 secretion from endothelial cells by stimulating particulate guanylate cyclase
    • Razandi M., Pedram A., Rubin T., and Levin E.R. PGE2 and PGI2 inhibit ET-1 secretion from endothelial cells by stimulating particulate guanylate cyclase. Am J Physiol 270 (1996) H1342-H1349
    • (1996) Am J Physiol , vol.270
    • Razandi, M.1    Pedram, A.2    Rubin, T.3    Levin, E.R.4
  • 85
    • 0032906087 scopus 로고    scopus 로고
    • Salt-sensitive hypertension and reduced fertility in mice lacking the rostaglandin EP2 receptor
    • Kennedy C., Zhang Y., Brandon S., Guan Y., Coffee K., Funk C.D., et al. Salt-sensitive hypertension and reduced fertility in mice lacking the rostaglandin EP2 receptor. Nat Med 5 (1999) 217-220
    • (1999) Nat Med , vol.5 , pp. 217-220
    • Kennedy, C.1    Zhang, Y.2    Brandon, S.3    Guan, Y.4    Coffee, K.5    Funk, C.D.6
  • 87
    • 0034796261 scopus 로고    scopus 로고
    • Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice
    • Sonoshita M., Takaku K., Sasaki N., Sugimoto Y., Ushikubi F., Narumiya S., et al. Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice. Nat Med 7 (2001) 1048-1051
    • (2001) Nat Med , vol.7 , pp. 1048-1051
    • Sonoshita, M.1    Takaku, K.2    Sasaki, N.3    Sugimoto, Y.4    Ushikubi, F.5    Narumiya, S.6
  • 88
    • 0141918838 scopus 로고    scopus 로고
    • Prostanoid receptor signaling relevant to tumor growth and angiogenesis
    • Majima M., Amano H., and Hayashi I. Prostanoid receptor signaling relevant to tumor growth and angiogenesis. Trends Pharmacol Sci 24 (2003) 524-529
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 524-529
    • Majima, M.1    Amano, H.2    Hayashi, I.3
  • 89
    • 0141679091 scopus 로고    scopus 로고
    • Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells
    • Salcedo R., Zhang X., Young H.A., Michael N., Wasserman K., Ma W.H., et al. Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells. Blood 102 (2003) 1966-1977
    • (2003) Blood , vol.102 , pp. 1966-1977
    • Salcedo, R.1    Zhang, X.2    Young, H.A.3    Michael, N.4    Wasserman, K.5    Ma, W.H.6
  • 90
    • 0035049227 scopus 로고    scopus 로고
    • Oxidized LDL regulates vascular endothelial growth factor expression in human macrophages and endothelial cells through activation of peroxisome proliferator-activated receptor-gamma
    • Inoue M., Itoh H., Tanaka T., Chun T.H., Doi K., Fukunaga Y., et al. Oxidized LDL regulates vascular endothelial growth factor expression in human macrophages and endothelial cells through activation of peroxisome proliferator-activated receptor-gamma. Arterioscler Thromb Vasc Biol 21 (2001) 560-566
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 560-566
    • Inoue, M.1    Itoh, H.2    Tanaka, T.3    Chun, T.H.4    Doi, K.5    Fukunaga, Y.6
  • 91
    • 0033605677 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo
    • Xin X., Yang S., Kowalski J., and Gerritsen M.E. Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo. J Biol Chem 274 (1999) 9116-9121
    • (1999) J Biol Chem , vol.274 , pp. 9116-9121
    • Xin, X.1    Yang, S.2    Kowalski, J.3    Gerritsen, M.E.4
  • 92
    • 2142701648 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma ligands inhibit choroidal neovascularization
    • Murata T., He S., Hangai M., Ishibashi T., Xi X.P., Kim S., et al. Peroxisome proliferator-activated receptor-gamma ligands inhibit choroidal neovascularization. Invest Ophthalmol Vis Sci 41 (2000) 2309-2317
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 2309-2317
    • Murata, T.1    He, S.2    Hangai, M.3    Ishibashi, T.4    Xi, X.P.5    Kim, S.6
  • 93
    • 20044376571 scopus 로고    scopus 로고
    • In vivo upregulation of CD95 and CD95L causes synergistic inhibition of angiogenesis by TSP1 peptide and metronomic doxorubicin treatment
    • Quesada A.J., Nelius T., Yap R., Zaichuk T.A., Alfranca A., Filleur S., et al. In vivo upregulation of CD95 and CD95L causes synergistic inhibition of angiogenesis by TSP1 peptide and metronomic doxorubicin treatment. Cell Death Differ 12 (2005) 649-658
    • (2005) Cell Death Differ , vol.12 , pp. 649-658
    • Quesada, A.J.1    Nelius, T.2    Yap, R.3    Zaichuk, T.A.4    Alfranca, A.5    Filleur, S.6
  • 94
    • 6344235259 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands improve the antitumor efficacy of thrombospondin peptide ABT510
    • Huang H., Campbell S.C., Bedford D.F., Nelius T., Veliceasa D., Shroff E.H., et al. Peroxisome proliferator-activated receptor gamma ligands improve the antitumor efficacy of thrombospondin peptide ABT510. Mol Cancer Res 2 (2004) 541-550
    • (2004) Mol Cancer Res , vol.2 , pp. 541-550
    • Huang, H.1    Campbell, S.C.2    Bedford, D.F.3    Nelius, T.4    Veliceasa, D.5    Shroff, E.H.6
  • 95
    • 0033567459 scopus 로고    scopus 로고
    • Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis
    • Daniel T.O., Liu H., Morrow J.D., Crews B.C., and Marnett L.J. Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis. Cancer Res 59 (1999) 4574-4577
    • (1999) Cancer Res , vol.59 , pp. 4574-4577
    • Daniel, T.O.1    Liu, H.2    Morrow, J.D.3    Crews, B.C.4    Marnett, L.J.5
  • 96
    • 0032407666 scopus 로고    scopus 로고
    • Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2
    • Thomas D.W., Mannon R.B., Mannon P.J., Latour A., Oliver J.A., Hoffman M., et al. Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2. J Clin Invest 102 (1998) 1994-2001
    • (1998) J Clin Invest , vol.102 , pp. 1994-2001
    • Thomas, D.W.1    Mannon, R.B.2    Mannon, P.J.3    Latour, A.4    Oliver, J.A.5    Hoffman, M.6
  • 97
    • 0030613757 scopus 로고    scopus 로고
    • The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth
    • Nguyen M., Camenisch T., Snouwaert J.N., Hicks E., Coffman T.M., Anderson P.W., et al. The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth. Nature 390 (1997) 78-81
    • (1997) Nature , vol.390 , pp. 78-81
    • Nguyen, M.1    Camenisch, T.2    Snouwaert, J.N.3    Hicks, E.4    Coffman, T.M.5    Anderson, P.W.6
  • 98
    • 0033213637 scopus 로고    scopus 로고
    • PPAR gamma is required for placental, cardiac, and adipose tissue development
    • Barak Y., Nelson M.C., Ong E.S., Jones Y.Z., Ruiz-Lozano P., Chien K.R., et al. PPAR gamma is required for placental, cardiac, and adipose tissue development. Mol Cell 4 (1999) 585-595
    • (1999) Mol Cell , vol.4 , pp. 585-595
    • Barak, Y.1    Nelson, M.C.2    Ong, E.S.3    Jones, Y.Z.4    Ruiz-Lozano, P.5    Chien, K.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.