Intracellular signaling pathway of FGF-2-modulated corneal endothelial cell migration during wound healing in vitro

Experimental Eye Research

Volumn 73, Issue 5, 2001, Pages 639-650

  Rieck, Peter W ^a   Cholidis, Symira ^a   Hartmann, Christian ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Cell culture; Corneal endothelial cells; Growth factors; Migration; Signal transduction

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ARACHIDONIC ACID; BASIC FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; GROWTH FACTOR; INDOMETACIN; NORDIHYDROGUAIARETIC ACID; PERTUSSIS TOXIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C;

ANIMAL CELL; ANIMAL TISSUE; ARACHIDONIC ACID METABOLISM; ARTICLE; CELL CULTURE; CELL MIGRATION; CONTROLLED STUDY; CORNEA CELL; ENDOTHELIUM CELL; NONHUMAN; PRIORITY JOURNAL; SECOND MESSENGER; SIGNAL TRANSDUCTION; WOUND HEALING;

EID: 0035659473     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.2001.1067     Document Type: Article

References (54)

1. In vivo binding of topically applied human bFGF on rabbit corneal epithelial wound
2. Autocrine angiotensin system regulation of bovine aortic endothelial cell migration and plasminogen activator involves modulation of proto-oncogene pp60c-src expression
3. Les signaux des FGF: Un mécanisme qui commence à être déchiffré
4. Two growth factor signaling pathways in fibroblasts distinguished by pertussis toxin
5. Phosphatidylinositol 3-kinase is required for insulin-like growth factor-I-induced vascular smooth muscle cell proliferation and migration
6. Primary structure of bovine brain acidic FGF
7. Signal transduction by bFGF, but not TGFβ1, involves arachidonic acid metabolism in endothelial cells
8. A heparin-binding angiogenic protein-basic fibroblast growth factor is stored within basement membrane
9. The effects of epidermal and fibroblast growth factors on the repair of corneal endothelial wounds in bovine corneas maintained in organ culture
10. Molecular and biological characterization of FGF, an angiogenic factor which also controls the proliferation and differentiation
11. Protein kinase C regulation of corneal endothelial cell proliferation and cell cycle
12. Fibroblast growth factor 2 uses distinct signaling pathways for cell proliferation and cell shape changes in corneal endothelial cells
13. Basic fibroblast growth factor stimulates corneal endothelial cell growth and endothelial wound healing of human corneas
14. Related fibroblast growth factor receptor genes exist in the human genome
15. Roles of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in stimulation of vascular smooth muscle cell migration and deoxyribonucleic acid synthesis by insulin-like growth factor-I
16. Corneal endothelial wound closure in vitro. Effects of EGF and/or indomethacin
17. Protein kinase C activation during corneal endothelial wound repair
18. 2subtype
19. 2synthesis
20. Fibroblast growth factor 2 uses PLC-gamma1 for cell proliferation and P13-kinase for alteration of cell shape and cell proliferation in corneal endothelial cells
21. Growth factors, signaling pathways, and the regulation of proliferation and differentiation in BC3H1 muscle cells. II. Two signaling pathways distinguished by pertussis toxin and a potential role for the ras oncogene
22. Ligand-affinity cloning and structure of a cell surface heparan sulfate proteoglycan that binds basic fibroblast growth factor
23. NGF activates similar intracellular signaling pathways in vascular smooth muscle cells as PDGF-BB but elicits different biological responses
24. Fibroblast growth factor receptor-1 mediates chemotaxis independently of direct SH-2-domain protein binding
25. Regeneration of cat corneal endothelium induced in vivo by fibroblast growth factor
26. Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor
27. 2is coupled to hormonally regulated release of arachidonic acid
28. Linking protein kinase C to cell-cycle control
29. Cellular migration and morphology in corneal endothelial wound repair
30. Anchoring proteins for protein kinase C, a means for isoenzyme selectivity
31. A tyrosine phosphorylated carboxy-terminal peptide of the FGF receptor (flg) is a binding site for the SH2 domain of phospholipase Cγ-1
32. Induction of angiogenesis in vitro by vanadate, an inhibitor of phosphotyrosine phosphatases
33. Colocalization of fibroblast growth factor binding sites with extracellular matrix components in normal and keratoconus corneas
34. Migration of retinal pigment epithelium cells in vitro is regulated by protein kinase C
35. Hepatocyte growth factor promotes migration of human hepatocellular carcinoma via phosphatidylinositol 3-kinase
36. Maintenance of corneal endothelial cell shape by prostaglandin E2. Effects of EGF and indomethacin
37. The molecular heterogeneity of protein kinase C and its implications for cellular regulation
38. Possible involvement of arachidonic acid metabolites in the synergistic action of endothelial mitogenesis by basic fibroblast growth factor and phorbol ester
39. Regulation of protein kinase C, a tale of lipids and proteins
40. The influence of basic fibroblast growth factor on cat corneal endothelial wound healing in vivo
41. Recombinant human basic fibroblast growth factor in three different wound models in rabbits. Corneal wound healing effect and pharmacology
42. Recombinant human bFGF stimulates corneal endothelial wound healing in rabbits
43. Role of exogenous/endogenous FGF-2 and TGFβ on human corneal endothelial cells proliferation in vitro
44. 2activity
45. Effects of human recombinant basic fibroblast growth factor on endothelial wound healing in organ culture of human cornea
46. Autocrine activities of basic fibroblast growth factor: Regulation of endothelial cell movement, plasminogen activator synthesis, and DNA-synthesis
47. The role of endogenous growth factors to support corneal endothelial migration in vitro
48. Basic fibroblast growth factor, expression in cultured cells derived from corneal endothelium and lens epithelium
49. Diversity of G proteins in signal transduction
50. Protein kinases
51. Endothelial wound repair in primate cornea
52. Specific binding of basic fibroblast growth factor to basement membrane-like structures and to purified heparan sulfate proteoglycan of the EHS tumor
53. Endothelial cell-derived basic fibroblast growth factor, synthesis and deposition into subendothelial extracellular matrix
54. Epidermal growth factor and its receptor, basic fibroblast growth factor, transforming growth factor beta-1, and interleukin-1 alpha messenger RNA production in human corneal endothelial cells