Activation of cellular invasion by trefoil peptides and src is mediated by cyclooxygenase- and thromboxane A2 receptor-dependent signaling pathways

FASEB Journal

Volumn 15, Issue 9, 2001, Pages 1517-1528

  Rodrigues, Sylvie ^a   Nguyen, Quang Dé ^a   Faivre, Sandrine ^a   Bruyneel, Erik ^b   Thim, Lars ^c   Westley, Bruce ^d   May, Felicity ^d   Flatau, Gilles ^e   Mareel, Marc ^b   Gespach, Christian ^a   Emami, Shahin ^a  

^a HÔPITAL SAINT ANTOINE   (France)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

^c NOVO NORDISK A S   (Denmark)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

^e INSERM   (France)

Author keywords

Cancer progression; Heterotrimeric G proteins; Inflammation; Phospholipase C; Rho like GTPases

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GUANOSINE TRIPHOSPHATASE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PHOSPHOLIPASE C INHIBITOR; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEIN TYROSINE KINASE; THROMBOXANE A2 RECEPTOR; THROMBOXANE A2 RECEPTOR BLOCKING AGENT; TREFOIL PEPTIDE;

ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INVASION; COLORECTAL CANCER; CONTROLLED STUDY; EPITHELIUM CELL; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; KIDNEY CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

CELL LINE, TRANSFORMED; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; GROWTH SUBSTANCES; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; INTESTINAL MUCOSA; ISOENZYMES; KIDNEY; MEMBRANE PROTEINS; MUCINS; MUSCLE PROTEINS; NEOPLASM INVASIVENESS; NEUROPEPTIDES; PEPTIDES; PHOSPHOLIPASE C; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEINS; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RECEPTORS, THROMBOXANE; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 17844368339     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.00-0802com     Document Type: Article

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