5-Lipoxygenase regulates malignant mesothelial cell survival: Involvement of vascular endothelial growth factor

FASEB Journal

Volumn 15, Issue 13, 2001, Pages 2326-2336

  Romano, Mario ^a,c   Catalano, Alfonso ^b   Nutini, Michele ^c   D'Urbano, Etrusca ^c   Crescenzi, Carlo ^c   Claria, Joan ^d   Libner, Roberta ^e   Davi, Giovanni ^c   Procopio, Antonio ^b  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^c UNIVERSITY OF CHIETI   (Italy)

^d HOSPITAL CLÍNIC   (Spain)

^e C Arrigo Children's Hospital   (Italy)

Author keywords

Angiogenesis; Apoptosis; Arachidonic acid; Eicosanoids; Mesothelioma

Indexed keywords

5 HYDROXYICOSATETRAENOIC ACID; ANTISENSE OLIGONUCLEOTIDE; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; COMPLEMENTARY DNA; LEUKOTRIENE B4; VASCULOTROPIN; VASCULOTROPIN ANTIBODY;

ANTIBODY DETECTION; APOPTOSIS; ARTICLE; CANCER CELL; CELL SURVIVAL; CONTROLLED STUDY; DNA SYNTHESIS; DRUG POTENCY; ENZYME REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOREGULATION; INHIBITION KINETICS; MESOTHELIUM; MESOTHELIUM CELL; NUCLEOSOME; PLEURA MESOTHELIOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; ARACHIDONATE 5-LIPOXYGENASE; ARACHIDONIC ACID; BENZOQUINONES; CELL DIVISION; CELL LINE; CELL SURVIVAL; DNA, ANTISENSE; ENDOTHELIAL GROWTH FACTORS; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GREEN FLUORESCENT PROTEINS; HUMANS; LIPOXYGENASE INHIBITORS; LUMINESCENT PROTEINS; LYMPHOKINES; MESOTHELIOMA; MUTATION; NORDIHYDROGUAIARETIC ACID; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; THYMIDINE; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TRITIUM; TUMOR CELLS, CULTURED; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0035162355     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.01-0150com     Document Type: Article

References (39)

1. Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: Evidence for a transcriptional effect
2. Δ716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)
3. Prostaglandin H synthases, nonsteroidal anti-inflammatory drugs, and colon cancer
4. Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors
5. Mammalian lipoxygenases: Molecular structures and functions
6. Lipoxin biosynthesis and its impact in inflammatory and vascular events
7. Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells
8. Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells
9. Arachidonate lipoxygenases are essential regulators of cell survival and apoptosis
10. Malignant pleural mesothelioma
11. Pathology of malignant mesothelioma
12. Asbestos fibres inhibit the in vitro activity of lymphokine-activated killer (LAK) cells from healthy individuals and patients with malignant mesothelioma
13. Circulating natural killer cells in retired asbestos cement workers
14. Simian virus 40-like DNA sequences in human pleural mesothelioma
15. A multi-institutional study confirms the presence and expression of simian virus 40 in human malignant mesotheliomas
16. Simian virus-40 large-T antigen binds p53 in human mesotheliomas
17. Human mesothelial cells are unusually susceptible to SV40-mediated transformation and asbestos co-carcinogenicity
18. Vascular endothelial growth factor is an autocrine growth factor in human malignant mesothelioma
19. Vascular endothelial growth factor levels and induction of permeability in malignant pleural effusions
20. Lipoxin generation by permeabilized human platelets
21. Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides
22. Determinants of 5-lipoxygenase nuclear localization using green fluorescent protein/5-lipoxygenase fusion proteins
23. Sp1 recognition sites in the proximal promoter of the human vascular endothelial growth factor gene are essential for platelet-derived growth factor-induced gene expression
24. Expression of platelet-derived growth factor (PDGF) and PDGF receptors in human malignant mesothelioma in vitro and in vivo
25. Angiogenic cytokines in mesothelioma: A study of VEGF, FGF-1 and -2, and TGF beta expression
26. Normal human mesothelial cells and mesothelioma cell lines express insulin-like growth factor I and associated molecules
27. Antisense oligonucleotides specific for transforming growth factor beta2 inhibit the growth of malignant mesothelioma both in vitro and in vivo
28. Characterization of the human 5-lipoxygenase gene promoter
29. Inhibition of fos-jun-DNA complex formation by dihydroguaiaretic acid and in vitro cytotoxic effects on cancer cells
30. Selective incorporation of (15S)-hydroxyeicosatetraenoic acid in phosphatidylinositol of human neutrophils: Agonist-induced deacylation and transformation of stored hydroxyeicosanoids
31. Lipoxin synthase activity of human platelet 12-Lipoxygenase
32. Lipid mediator networks in cell signaling: Update and impact of cytokines
33. Human mesothelioma samples overexpress both cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (NOS2): In vitro antiproliferative effects of a COX-2 inhibitor
34. Cyclooxygenase regulates angiogenesis induced by colon cancer cells
35. Host cyclooxygenase-2 modulates carcinoma growth
36. Eicosanoid regulation of angiogenesis: Role of endothelial arachidonate 12-lipoxygenase
37. Effects of high glucose on vascular endothelial growth factor expression in vascular smooth muscle cells
38. Prostaglandins induce vascular endothelial growth factor in a human monocytic cell line and rat lungs via cAMP
39. Prostaglandin E2 induces vascular endothelial growth factor and basic fibroblast growth factor mRNA expression in cultured rat Muller cells