Key role of 15-lipoxygenase/15-hydroxyeicosatetraenoic acid in pulmonary vascular remodeling and vascular angiogenesis associated with hypoxic pulmonary hypertension

Hypertension

Volumn 58, Issue 4, 2011, Pages 679-688

  Ma, Cui ^a   Li, Yaqian ^a   Ma, Jun ^a   Liu, Yun ^a   Li, Qian ^a   Niu, Shengpan ^a   Shen, Zhiying ^a   Zhang, Lei ^a   Pan, Zhenwei ^a   Zhu, Daling ^a,b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Bio pharmaceutical Key Laboratory of Heilongjiang Province   (China)

Author keywords

15 hydroxyeicosatetraenoic acid; angiogenesis; pulmonary hypertension; pulmonary vascular remodeling; ROCK

Indexed keywords

15 HYDROXYICOSATETRAENOIC ACID; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ARACHIDONATE 15 LIPOXYGENASE; BROXURIDINE; CINNAMYL 3,4 DIHYDROXY ALPHA CYANOCINNAMATE; LIPOXYGENASE INHIBITOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL MIGRATION; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG INHIBITION; ENDOTHELIUM CELL; HEART HYPERTROPHY; HEART SURGERY; HUMAN; HYPOXIA; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY ARTERY ENDOTHELIAL CELL; PULMONARY HYPERTENSION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TREATMENT OUTCOME;

ANIMALS; ANOXIA; ARACHIDONATE 15-LIPOXYGENASE; CATTLE; CELL CYCLE; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CHICK EMBRYO; CHORIOALLANTOIC MEMBRANE; ENDOTHELIUM, VASCULAR; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; HYPERTENSION, PULMONARY; MALE; MODELS, ANIMAL; MUSCLE, SMOOTH, VASCULAR; NEOVASCULARIZATION, PATHOLOGIC; PULMONARY ARTERY; RATS; RATS, WISTAR; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION;

EID: 80053574010     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.111.171561     Document Type: Article

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