Baicalein potently suppresses angiogenesis induced by vascular endothelial growth factor through the p53/Rb signaling pathway leading to G1/s cell cycle arrest

Experimental Biology and Medicine

Volumn 236, Issue 7, 2011, Pages 851-858

  Ling, Yun ^a   Chen, Yan ^a   Chen, Pu ^a   Hui, Hui ^a   Song, Xiuming ^a   Lu, Zhijian ^a   Li, Chenglin ^a   Lu, Na ^a   Guo, Qinglong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Angiogenesis; Baicalein; G1 s arrest; P53 Rb signals; VEGF

Indexed keywords

ANGIOGENESIS INHIBITOR; BAICALEIN; CYCLIN D; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN E; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P16; PROTEIN P21; PROTEIN P27; PROTEIN P53; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL MIGRATION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION;

ANGIOGENESIS INHIBITORS; ANIMALS; CELL CYCLE; CELLS, CULTURED; FLAVANONES; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

RATTUS;

EID: 79960666903     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2011.010395     Document Type: Article

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