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Volumn 35, Issue 9, 2016, Pages 909-923

Interplay between Fanconi anemia and homologous recombination pathways in genome integrity

Author keywords

DNA damage response; DNA repair; Fanconi anemia; genome stability; homologous recombination; replication stress

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; DNA; FANCI PROTEIN; FANCJ PROTEIN; FANCONI ANEMIA GROUP D2 PROTEIN; UNCLASSIFIED DRUG; DNA LIGASE; FANCONI ANEMIA PROTEIN;

EID: 84963657302     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201693860     Document Type: Review
Times cited : (151)

References (148)
  • 2
    • 0029861118 scopus 로고    scopus 로고
    • Fanconi's anemia and malignancies
    • Alter BP, (1996) Fanconi's anemia and malignancies. Am J Hematol 53: 99-110
    • (1996) Am J Hematol , vol.53 , pp. 99-110
    • Alter, B.P.1
  • 3
    • 33645836146 scopus 로고    scopus 로고
    • The association between FANCD1/BRCA2 mutations and leukaemia
    • Alter BP, (2006) The association between FANCD1/BRCA2 mutations and leukaemia. Br J Haematol 133: 446-448
    • (2006) Br J Haematol , vol.133 , pp. 446-448
    • Alter, B.P.1
  • 4
    • 84920115536 scopus 로고    scopus 로고
    • Telomere length in inherited bone marrow failure syndromes
    • Alter BP, Giri N, Savage SA, Rosenberg PS, (2015) Telomere length in inherited bone marrow failure syndromes. Haematologica 100: 49-54
    • (2015) Haematologica , vol.100 , pp. 49-54
    • Alter, B.P.1    Giri, N.2    Savage, S.A.3    Rosenberg, P.S.4
  • 6
    • 0033740880 scopus 로고    scopus 로고
    • Prevalence and penetrance of BRCA1 and BRCA2 mutations in a population-based series of breast cancer cases
    • Anglian Breast Cancer Study Group
    • Anglian Breast Cancer Study Group (2000) Prevalence and penetrance of BRCA1 and BRCA2 mutations in a population-based series of breast cancer cases. Br J Cancer 83: 1301-1308
    • (2000) Br J Cancer , vol.83 , pp. 1301-1308
  • 8
    • 0002457273 scopus 로고    scopus 로고
    • Fanconi Anemia
    • Scriver C. Beaudet A.L. Sly W.S. Valle D. Vogelstein B. Childs B. (eds), New York: McGraw-Hill Medical
    • Auerbach AD, Buchwald M, Joenje H, (2001) Fanconi Anemia. In Metabolic and Molecular Bases of Inherited Disease, Scriver C, Beaudet AL, Sly WS, Valle D, Vogelstein B, Childs B, (eds), pp 753-768. New York: McGraw-Hill Medical
    • (2001) Metabolic and Molecular Bases of Inherited Disease , pp. 753-768
    • Auerbach, A.D.1    Buchwald, M.2    Joenje, H.3
  • 9
    • 0024543636 scopus 로고
    • International Fanconi anemia registry: Relation of clinical symptoms to diepoxybutane sensitivity
    • Auerbach AD, Rogatko A, Schroeder-Kurth TM, (1989) International Fanconi anemia registry: relation of clinical symptoms to diepoxybutane sensitivity. Blood 73: 391-396
    • (1989) Blood , vol.73 , pp. 391-396
    • Auerbach, A.D.1    Rogatko, A.2    Schroeder-Kurth, T.M.3
  • 10
    • 0017118656 scopus 로고
    • Susceptibility of Fanconi's anaemia fibroblasts to chromosome damage by carcinogens
    • Auerbach AD, Wolman SR, (1976) Susceptibility of Fanconi's anaemia fibroblasts to chromosome damage by carcinogens. Nature 261: 494-496
    • (1976) Nature , vol.261 , pp. 494-496
    • Auerbach, A.D.1    Wolman, S.R.2
  • 11
    • 84885844201 scopus 로고    scopus 로고
    • DNA replication and homologous recombination factors: Acting together to maintain genome stability
    • Aze A, Zhou JC, Costa A, Costanzo V, (2013) DNA replication and homologous recombination factors: acting together to maintain genome stability. Chromosoma 122: 401-413
    • (2013) Chromosoma , vol.122 , pp. 401-413
    • Aze, A.1    Zhou, J.C.2    Costa, A.3    Costanzo, V.4
  • 16
    • 84866358168 scopus 로고    scopus 로고
    • The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance
    • Bouwman P, Jonkers J, (2012) The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance. Nat Rev Cancer 12: 587-598
    • (2012) Nat Rev Cancer , vol.12 , pp. 587-598
    • Bouwman, P.1    Jonkers, J.2
  • 17
    • 84942039168 scopus 로고    scopus 로고
    • Regulation of the Rev1-pol zeta complex during bypass of a DNA interstrand cross-link
    • Budzowska M, Graham TG, Sobeck A, Waga S, Walter JC, (2015) Regulation of the Rev1-pol zeta complex during bypass of a DNA interstrand cross-link. EMBO J 34: 1971-1985
    • (2015) EMBO J , vol.34 , pp. 1971-1985
    • Budzowska, M.1    Graham, T.G.2    Sobeck, A.3    Waga, S.4    Walter, J.C.5
  • 22
    • 67349227137 scopus 로고    scopus 로고
    • Replication stress induces sister-chromatid bridging at fragile site loci in mitosis
    • Chan KL, Palmai-Pallag T, Ying S, Hickson ID, (2009) Replication stress induces sister-chromatid bridging at fragile site loci in mitosis. Nat Cell Biol 11: 753-760
    • (2009) Nat Cell Biol , vol.11 , pp. 753-760
    • Chan, K.L.1    Palmai-Pallag, T.2    Ying, S.3    Hickson, I.D.4
  • 23
    • 84880534493 scopus 로고    scopus 로고
    • FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery
    • Chaudhury I, Sareen A, Raghunandan M, Sobeck A, (2013) FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery. Nucleic Acids Res 41: 6444-6459
    • (2013) Nucleic Acids Res , vol.41 , pp. 6444-6459
    • Chaudhury, I.1    Sareen, A.2    Raghunandan, M.3    Sobeck, A.4
  • 24
    • 84954386307 scopus 로고    scopus 로고
    • A novel role for non-ubiquitinated FANCD2 in response to hydroxyurea-induced DNA damage
    • Chen X, Bosques L, Sung P, Kupfer GM, (2015a) A novel role for non-ubiquitinated FANCD2 in response to hydroxyurea-induced DNA damage. Oncogene 35: 22-34
    • (2015) Oncogene , vol.35 , pp. 22-34
    • Chen, X.1    Bosques, L.2    Sung, P.3    Kupfer, G.M.4
  • 27
    • 0036699095 scopus 로고    scopus 로고
    • Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA
    • Cheung I, Schertzer M, Rose A, Lansdorp PM, (2002) Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA. Nat Genet 31: 405-409
    • (2002) Nat Genet , vol.31 , pp. 405-409
    • Cheung, I.1    Schertzer, M.2    Rose, A.3    Lansdorp, P.M.4
  • 32
    • 33749007676 scopus 로고    scopus 로고
    • Mouse models of BRCA1 and BRCA2 deficiency: Past lessons, current understanding and future prospects
    • Evers B, Jonkers J, (2006) Mouse models of BRCA1 and BRCA2 deficiency: past lessons, current understanding and future prospects. Oncogene 25: 5885-5897
    • (2006) Oncogene , vol.25 , pp. 5885-5897
    • Evers, B.1    Jonkers, J.2
  • 39
    • 55849133052 scopus 로고    scopus 로고
    • Remodeling of DNA replication structures by the branch point translocase FANCM
    • Gari K, Decaillet C, Delannoy M, Wu L, Constantinou A, (2008) Remodeling of DNA replication structures by the branch point translocase FANCM. Proc Natl Acad Sci USA 105: 16107-16112
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16107-16112
    • Gari, K.1    Decaillet, C.2    Delannoy, M.3    Wu, L.4    Constantinou, A.5
  • 40
    • 57349106091 scopus 로고    scopus 로고
    • Chromosomal instability syndromes are sensitive to poly ADP-ribose polymerase inhibitors
    • Gaymes TJ, Shall S, Farzaneh F, Mufti GJ, (2008) Chromosomal instability syndromes are sensitive to poly ADP-ribose polymerase inhibitors. Haematologica 93: 1886-1889
    • (2008) Haematologica , vol.93 , pp. 1886-1889
    • Gaymes, T.J.1    Shall, S.2    Farzaneh, F.3    Mufti, G.J.4
  • 43
    • 75949092280 scopus 로고    scopus 로고
    • BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control
    • Gong Z, Kim JE, Leung CC, Glover JN, Chen J, (2010) BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control. Mol Cell 37: 438-446
    • (2010) Mol Cell , vol.37 , pp. 438-446
    • Gong, Z.1    Kim, J.E.2    Leung, C.C.3    Glover, J.N.4    Chen, J.5
  • 44
    • 34948855936 scopus 로고    scopus 로고
    • FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein
    • Gupta R, Sharma S, Sommers JA, Kenny MK, Cantor SB, Brosh RM Jr, (2007) FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein. Blood 110: 2390-2398
    • (2007) Blood , vol.110 , pp. 2390-2398
    • Gupta, R.1    Sharma, S.2    Sommers, J.A.3    Kenny, M.K.4    Cantor, S.B.5    Brosh, R.M.6
  • 45
    • 84855427966 scopus 로고    scopus 로고
    • RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks
    • Hashimoto Y, Puddu F, Costanzo V, (2012) RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks. Nat Struct Mol Biol 19: 17-24
    • (2012) Nat Struct Mol Biol , vol.19 , pp. 17-24
    • Hashimoto, Y.1    Puddu, F.2    Costanzo, V.3
  • 48
    • 14644391577 scopus 로고    scopus 로고
    • The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability
    • Howlett NG, Taniguchi T, Durkin SG, D'Andrea AD, Glover TW, (2005) The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability. Hum Mol Genet 14: 693-701
    • (2005) Hum Mol Genet , vol.14 , pp. 693-701
    • Howlett, N.G.1    Taniguchi, T.2    Durkin, S.G.3    D'Andrea, A.D.4    Glover, T.W.5
  • 50
    • 77955505023 scopus 로고    scopus 로고
    • The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response
    • Huang M, Kim JM, Shiotani B, Yang K, Zou L, D'Andrea AD, (2010) The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response. Mol Cell 39: 259-268
    • (2010) Mol Cell , vol.39 , pp. 259-268
    • Huang, M.1    Kim, J.M.2    Shiotani, B.3    Yang, K.4    Zou, L.5    D'Andrea, A.D.6
  • 52
    • 74749095240 scopus 로고    scopus 로고
    • Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins
    • Ilves I, Petojevic T, Pesavento JJ, Botchan MR, (2010) Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins. Mol Cell 37: 247-258
    • (2010) Mol Cell , vol.37 , pp. 247-258
    • Ilves, I.1    Petojevic, T.2    Pesavento, J.J.3    Botchan, M.R.4
  • 53
    • 84876886904 scopus 로고    scopus 로고
    • Regulation of DNA damage responses by ubiquitin and SUMO
    • Jackson SP, Durocher D, (2013) Regulation of DNA damage responses by ubiquitin and SUMO. Mol Cell 49: 795-807
    • (2013) Mol Cell , vol.49 , pp. 795-807
    • Jackson, S.P.1    Durocher, D.2
  • 54
    • 84874968077 scopus 로고    scopus 로고
    • BRCA2 is epistatic to the RAD51 paralogs in response to DNA damage
    • Jensen RB, Ozes A, Kim T, Estep A, Kowalczykowski SC, (2013) BRCA2 is epistatic to the RAD51 paralogs in response to DNA damage. DNA Repair 12: 306-311
    • (2013) DNA Repair , vol.12 , pp. 306-311
    • Jensen, R.B.1    Ozes, A.2    Kim, T.3    Estep, A.4    Kowalczykowski, S.C.5
  • 55
    • 0035379611 scopus 로고    scopus 로고
    • The emerging genetic and molecular basis of Fanconi anaemia
    • Joenje H, Patel KJ, (2001) The emerging genetic and molecular basis of Fanconi anaemia. Nat Rev Genet 2: 446-459
    • (2001) Nat Rev Genet , vol.2 , pp. 446-459
    • Joenje, H.1    Patel, K.J.2
  • 56
    • 0035734285 scopus 로고    scopus 로고
    • Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
    • Jonkers J, Meuwissen R, van der Gulden H, Peterse H, van der Valk M, Berns A, (2001) Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Nat Genet 29: 418-425
    • (2001) Nat Genet , vol.29 , pp. 418-425
    • Jonkers, J.1    Meuwissen, R.2    Van Der Gulden, H.3    Peterse, H.4    Van Der Valk, M.5    Berns, A.6
  • 59
    • 77955889790 scopus 로고    scopus 로고
    • Expanded roles of the Fanconi anemia pathway in preserving genomic stability
    • Kee Y, D'Andrea AD, (2010) Expanded roles of the Fanconi anemia pathway in preserving genomic stability. Genes Dev 24: 1680-1694
    • (2010) Genes Dev , vol.24 , pp. 1680-1694
    • Kee, Y.1    D'Andrea, A.D.2
  • 61
    • 84863670930 scopus 로고    scopus 로고
    • Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway
    • Kim H, D'Andrea AD, (2012) Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway. Genes Dev 26: 1393-1408
    • (2012) Genes Dev , vol.26 , pp. 1393-1408
    • Kim, H.1    D'Andrea, A.D.2
  • 63
    • 84872082435 scopus 로고    scopus 로고
    • Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4
    • Kim Y, Spitz GS, Veturi U, Lach FP, Auerbach AD, Smogorzewska A, (2013) Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4. Blood 121: 54-63
    • (2013) Blood , vol.121 , pp. 54-63
    • Kim, Y.1    Spitz, G.S.2    Veturi, U.3    Lach, F.P.4    Auerbach, A.D.5    Smogorzewska, A.6
  • 64
    • 0142178215 scopus 로고    scopus 로고
    • Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2
    • King M-C, Marks J, Mandell J, (2003) Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science 302: 643-646
    • (2003) Science , vol.302 , pp. 643-646
    • King, M.-C.1    Marks, J.2    Mandell, J.3
  • 66
    • 84872578210 scopus 로고    scopus 로고
    • Fanconi anaemia and the repair of Watson and Crick DNA crosslinks
    • Kottemann MC, Smogorzewska A, (2013) Fanconi anaemia and the repair of Watson and Crick DNA crosslinks. Nature 493: 356-363
    • (2013) Nature , vol.493 , pp. 356-363
    • Kottemann, M.C.1    Smogorzewska, A.2
  • 67
    • 45449102827 scopus 로고    scopus 로고
    • Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. Elegans
    • Kruisselbrink E, Guryev V, Brouwer K, Pontier DB, Cuppen E, Tijsterman M, (2008) Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. elegans. Curr Biol 18: 900-905
    • (2008) Curr Biol , vol.18 , pp. 900-905
    • Kruisselbrink, E.1    Guryev, V.2    Brouwer, K.3    Pontier, D.B.4    Cuppen, E.5    Tijsterman, M.6
  • 69
    • 79960037006 scopus 로고    scopus 로고
    • Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice
    • Langevin F, Crossan GP, Rosado IV, Arends MJ, Patel KJ, (2011) Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice. Nature 475: 53-58
    • (2011) Nature , vol.475 , pp. 53-58
    • Langevin, F.1    Crossan, G.P.2    Rosado, I.V.3    Arends, M.J.4    Patel, K.J.5
  • 72
  • 73
    • 0347991859 scopus 로고    scopus 로고
    • Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein
    • Lomonosov M, Anand S, Sangrithi M, Davies R, Venkitaraman AR, (2003) Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein. Genes Dev 17: 3017-3022
    • (2003) Genes Dev , vol.17 , pp. 3017-3022
    • Lomonosov, M.1    Anand, S.2    Sangrithi, M.3    Davies, R.4    Venkitaraman, A.R.5
  • 75
    • 84920996478 scopus 로고    scopus 로고
    • BRCA1 promotes unloading of the CMG helicase from a stalled DNA replication fork
    • Long DT, Joukov V, Budzowska M, Walter JC, (2014) BRCA1 promotes unloading of the CMG helicase from a stalled DNA replication fork. Mol Cell 56: 174-185
    • (2014) Mol Cell , vol.56 , pp. 174-185
    • Long, D.T.1    Joukov, V.2    Budzowska, M.3    Walter, J.C.4
  • 76
    • 79959843168 scopus 로고    scopus 로고
    • Mechanism of RAD51-dependent DNA interstrand cross-link repair
    • Long DT, Raschle M, Joukov V, Walter JC, (2011) Mechanism of RAD51-dependent DNA interstrand cross-link repair. Science 333: 84-87
    • (2011) Science , vol.333 , pp. 84-87
    • Long, D.T.1    Raschle, M.2    Joukov, V.3    Walter, J.C.4
  • 78
    • 77149123028 scopus 로고    scopus 로고
    • FANCM regulates DNA chain elongation and is stabilized by S-phase checkpoint signalling
    • Luke-Glaser S, Luke B, Grossi S, Constantinou A, (2010) FANCM regulates DNA chain elongation and is stabilized by S-phase checkpoint signalling. EMBO J 29: 795-805
    • (2010) EMBO J , vol.29 , pp. 795-805
    • Luke-Glaser, S.1    Luke, B.2    Grossi, S.3    Constantinou, A.4
  • 80
    • 84949995795 scopus 로고    scopus 로고
    • FANCJ suppresses microsatellite instability and lymphomagenesis independent of the Fanconi anemia pathway
    • Matsuzaki K, Borel V, Adelman CA, Schindler D, Boulton SJ, (2015) FANCJ suppresses microsatellite instability and lymphomagenesis independent of the Fanconi anemia pathway. Genes Dev 29: 2532-2546
    • (2015) Genes Dev , vol.29 , pp. 2532-2546
    • Matsuzaki, K.1    Borel, V.2    Adelman, C.A.3    Schindler, D.4    Boulton, S.J.5
  • 85
    • 79951857925 scopus 로고    scopus 로고
    • DNA end resection-unraveling the tail
    • Mimitou EP, Symington LS, (2011) DNA end resection-unraveling the tail. DNA Repair 10: 344-348
    • (2011) DNA Repair , vol.10 , pp. 344-348
    • Mimitou, E.P.1    Symington, L.S.2
  • 87
    • 0035099044 scopus 로고    scopus 로고
    • BRCA2 is required for homology-directed repair of chromosomal breaks
    • Moynahan ME, Pierce AJ, Jasin M, (2001) BRCA2 is required for homology-directed repair of chromosomal breaks. Mol Cell 7: 263-272
    • (2001) Mol Cell , vol.7 , pp. 263-272
    • Moynahan, M.E.1    Pierce, A.J.2    Jasin, M.3
  • 88
    • 67349187702 scopus 로고    scopus 로고
    • The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities
    • Naim V, Rosselli F, (2009) The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities. Nat Cell Biol 11: 761-768
    • (2009) Nat Cell Biol , vol.11 , pp. 761-768
    • Naim, V.1    Rosselli, F.2
  • 93
    • 17644369692 scopus 로고    scopus 로고
    • Fanconi anemia complementation group D2 (FANCD2) functions independently of BRCA2- and RAD51-associated homologous recombination in response to DNA damage
    • Ohashi A, Zdzienicka MZ, Chen J, Couch FJ, (2005) Fanconi anemia complementation group D2 (FANCD2) functions independently of BRCA2- and RAD51-associated homologous recombination in response to DNA damage. J Biol Chem 280: 14877-14883
    • (2005) J Biol Chem , vol.280 , pp. 14877-14883
    • Ohashi, A.1    Zdzienicka, M.Z.2    Chen, J.3    Couch, F.J.4
  • 99
    • 84964789673 scopus 로고    scopus 로고
    • Breast cancer cells with deficiencies in BRCA1/BRCA2 show hypersensitivity to mitomycin C
    • Powell SN, Xia F, Zhang J, Feng Z, (2002) Breast cancer cells with deficiencies in BRCA1/BRCA2 show hypersensitivity to mitomycin C. Int J Radiat Oncol 54: 52
    • (2002) Int J Radiat Oncol , vol.54 , pp. 52
    • Powell, S.N.1    Xia, F.2    Zhang, J.3    Feng, Z.4
  • 105
    • 77950536222 scopus 로고    scopus 로고
    • FANCC suppresses short telomere-initiated telomere sister chromatid exchange
    • Rhee DB, Wang Y, Mizesko M, Zhou F, Haneline L, Liu Y, (2010) FANCC suppresses short telomere-initiated telomere sister chromatid exchange. Hum Mol Genet 19: 879-887
    • (2010) Hum Mol Genet , vol.19 , pp. 879-887
    • Rhee, D.B.1    Wang, Y.2    Mizesko, M.3    Zhou, F.4    Haneline, L.5    Liu, Y.6
  • 108
    • 84555196106 scopus 로고    scopus 로고
    • BRCA1 and BRCA2: Different roles in a common pathway of genome protection
    • Roy R, Chun J, Powell SN, (2012) BRCA1 and BRCA2: different roles in a common pathway of genome protection. Nat Rev Cancer 12: 68-78
    • (2012) Nat Rev Cancer , vol.12 , pp. 68-78
    • Roy, R.1    Chun, J.2    Powell, S.N.3
  • 109
    • 10744227178 scopus 로고    scopus 로고
    • Mutational analysis of the BRCA1-interacting genes ZNF350/ZBRK1 and BRIP1/BACH1 among BRCA1 and BRCA2-negative probands from breast-ovarian cancer families and among early-onset breast cancer cases and reference individuals
    • Rutter JL, Smith AM, Davila MR, Sigurdson AJ, Giusti RM, Pineda MA, Doody MM, Tucker MA, Greene MH, Zhang J, Struewing JP, (2003) Mutational analysis of the BRCA1-interacting genes ZNF350/ZBRK1 and BRIP1/BACH1 among BRCA1 and BRCA2-negative probands from breast-ovarian cancer families and among early-onset breast cancer cases and reference individuals. Hum Mutat 22: 121-128
    • (2003) Hum Mutat , vol.22 , pp. 121-128
    • Rutter, J.L.1    Smith, A.M.2    Davila, M.R.3    Sigurdson, A.J.4    Giusti, R.M.5    Pineda, M.A.6    Doody, M.M.7    Tucker, M.A.8    Greene, M.H.9    Zhang, J.10    Struewing, J.P.11
  • 113
    • 79955799175 scopus 로고    scopus 로고
    • Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11
    • Schlacher K, Christ N, Siaud N, Egashira A, Wu H, Jasin M, (2011) Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11. Cell 145: 529-542
    • (2011) Cell , vol.145 , pp. 529-542
    • Schlacher, K.1    Christ, N.2    Siaud, N.3    Egashira, A.4    Wu, H.5    Jasin, M.6
  • 114
    • 84863753191 scopus 로고    scopus 로고
    • A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2
    • Schlacher K, Wu H, Jasin M, (2012) A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2. Cancer Cell 22: 106-116
    • (2012) Cancer Cell , vol.22 , pp. 106-116
    • Schlacher, K.1    Wu, H.2    Jasin, M.3
  • 115
    • 77149135723 scopus 로고    scopus 로고
    • ATR activation and replication fork restart are defective in FANCM-deficient cells
    • Schwab RA, Blackford AN, Niedzwiedz W, (2010) ATR activation and replication fork restart are defective in FANCM-deficient cells. EMBO J 29: 806-818
    • (2010) EMBO J , vol.29 , pp. 806-818
    • Schwab, R.A.1    Blackford, A.N.2    Niedzwiedz, W.3
  • 118
    • 84876343734 scopus 로고    scopus 로고
    • FANCJ couples replication past natural fork barriers with maintenance of chromatin structure
    • Schwab RA, Nieminuszczy J, Shin-ya K, Niedzwiedz W, (2013) FANCJ couples replication past natural fork barriers with maintenance of chromatin structure. J Cell Biol 201: 33-48
    • (2013) J Cell Biol , vol.201 , pp. 33-48
    • Schwab, R.A.1    Nieminuszczy, J.2    Shin-Ya, K.3    Niedzwiedz, W.4
  • 121
    • 84887081781 scopus 로고    scopus 로고
    • Identification of proteins at active, stalled, and collapsed replication forks using isolation of proteins on nascent DNA (iPOND) coupled with mass spectrometry
    • Sirbu BM, McDonald WH, Dungrawala H, Badu-Nkansah A, Kavanaugh GM, Chen Y, Tabb DL, Cortez D, (2013) Identification of proteins at active, stalled, and collapsed replication forks using isolation of proteins on nascent DNA (iPOND) coupled with mass spectrometry. J Biol Chem 288: 31458-31467
    • (2013) J Biol Chem , vol.288 , pp. 31458-31467
    • Sirbu, B.M.1    McDonald, W.H.2    Dungrawala, H.3    Badu-Nkansah, A.4    Kavanaugh, G.M.5    Chen, Y.6    Tabb, D.L.7    Cortez, D.8
  • 124
    • 0026521238 scopus 로고
    • Cloning of cDNAs for Fanconi's anaemia by functional complementation
    • Strathdee CA, Gavish H, Shannon WR, Buchwald M, (1992) Cloning of cDNAs for Fanconi's anaemia by functional complementation. Nature 356: 763-767
    • (1992) Nature , vol.356 , pp. 763-767
    • Strathdee, C.A.1    Gavish, H.2    Shannon, W.R.3    Buchwald, M.4
  • 126
    • 81955162971 scopus 로고    scopus 로고
    • RAD51 paralogs: Roles in DNA damage signalling, recombinational repair and tumorigenesis
    • Suwaki N, Klare K, Tarsounas M, (2011) RAD51 paralogs: roles in DNA damage signalling, recombinational repair and tumorigenesis. Semin Cell Dev Biol 22: 898-905
    • (2011) Semin Cell Dev Biol , vol.22 , pp. 898-905
    • Suwaki, N.1    Klare, K.2    Tarsounas, M.3
  • 127
    • 84929945456 scopus 로고    scopus 로고
    • How homologous recombination maintains telomere integrity
    • Tacconi EM, Tarsounas M, (2015) How homologous recombination maintains telomere integrity. Chromosoma 124: 119-130
    • (2015) Chromosoma , vol.124 , pp. 119-130
    • Tacconi, E.M.1    Tarsounas, M.2
  • 130
    • 52049125947 scopus 로고    scopus 로고
    • Replication fork arrest, recombination and the maintenance of ribosomal DNA stability
    • Tsang E, Carr AM, (2008) Replication fork arrest, recombination and the maintenance of ribosomal DNA stability. DNA Repair (Amst) 7: 1613-1623
    • (2008) DNA Repair (Amst) , vol.7 , pp. 1613-1623
    • Tsang, E.1    Carr, A.M.2
  • 132
    • 63049108452 scopus 로고    scopus 로고
    • Linking the cellular functions of BRCA genes to cancer pathogenesis and treatment
    • Venkitaraman AR, (2009) Linking the cellular functions of BRCA genes to cancer pathogenesis and treatment. Annu Rev Pathol 4: 461-487
    • (2009) Annu Rev Pathol , vol.4 , pp. 461-487
    • Venkitaraman, A.R.1
  • 135
    • 2942705849 scopus 로고    scopus 로고
    • Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin
    • Wang X, Andreassen PR, D'Andrea AD, (2004) Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin. Mol Cell Biol 24: 5850-5862
    • (2004) Mol Cell Biol , vol.24 , pp. 5850-5862
    • Wang, X.1    Andreassen, P.R.2    D'Andrea, A.D.3
  • 137
    • 84920942368 scopus 로고    scopus 로고
    • SnapShot: Fanconi anemia and associated proteins
    • Wang AT, Smogorzewska A, (2015) SnapShot: Fanconi anemia and associated proteins. Cell 160: 354-354.e1
    • (2015) Cell , vol.160 , pp. 354-354e1
    • Wang, A.T.1    Smogorzewska, A.2
  • 139
    • 44949114282 scopus 로고    scopus 로고
    • FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability
    • Wu Y, Shin-ya K, Brosh RM Jr, (2008) FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability. Mol Cell Biol 28: 4116-4128
    • (2008) Mol Cell Biol , vol.28 , pp. 4116-4128
    • Wu, Y.1    Shin-Ya, K.2    Brosh, R.M.3
  • 143
  • 144
    • 84891301320 scopus 로고    scopus 로고
    • Causes and consequences of replication stress
    • Zeman MK, Cimprich KA, (2014) Causes and consequences of replication stress. Nat Cell Biol 16: 2-9
    • (2014) Nat Cell Biol , vol.16 , pp. 2-9
    • Zeman, M.K.1    Cimprich, K.A.2
  • 145
    • 78649334861 scopus 로고    scopus 로고
    • FANCJ/BRIP1 recruitment and regulation of FANCD2 in DNA damage responses
    • Zhang F, Fan Q, Ren K, Auerbach AD, Andreassen PR, (2010) FANCJ/BRIP1 recruitment and regulation of FANCD2 in DNA damage responses. Chromosoma 119: 637-649
    • (2010) Chromosoma , vol.119 , pp. 637-649
    • Zhang, F.1    Fan, Q.2    Ren, K.3    Auerbach, A.D.4    Andreassen, P.R.5
  • 146
    • 84902112143 scopus 로고    scopus 로고
    • Mechanism and regulation of incisions during DNA interstrand cross-link repair
    • Zhang J, Walter JC, (2014) Mechanism and regulation of incisions during DNA interstrand cross-link repair. DNA Repair 19: 135-142
    • (2014) DNA Repair , vol.19 , pp. 135-142
    • Zhang, J.1    Walter, J.C.2
  • 147
    • 78649319824 scopus 로고    scopus 로고
    • Screening RAD51C nucleotide alterations in patients with a family history of breast and ovarian cancer
    • Zheng Y, Zhang J, Hope K, Niu Q, Huo D, Olopade O, (2010) Screening RAD51C nucleotide alterations in patients with a family history of breast and ovarian cancer. Breast Cancer Res Treat 124: 857-861
    • (2010) Breast Cancer Res Treat , vol.124 , pp. 857-861
    • Zheng, Y.1    Zhang, J.2    Hope, K.3    Niu, Q.4    Huo, D.5    Olopade, O.6


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