Hematopoietic Dysfunction in a Mouse Model for Fanconi Anemia Group D1

Molecular Therapy

Volumn 14, Issue 4, 2006, Pages 525-535

  Navarro, Susana ^a   Meza, Nestor W ^a   Quintana Bustamante, Oscar ^a   Casado, José A ^a   Jacome, Ariana ^a   McAllister, Kimberly ^b   Puerto, Silvia ^c   Surrallés, Jordi ^c   Segovia, José C ^a   Bueren, Juan A ^a  

^a CIEMAT   (Spain)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Brca2; competitive repopulation ability; DNA repair; Fancd1; Fanconi anemia; genetic instability; hematopoiesis; hematopoietic stem cells; mitomycin C; self renewal

Indexed keywords

BRCA2 PROTEIN; DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CANCER SUSCEPTIBILITY; CELL COUNT; CELL POPULATION; CELL PROLIFERATION; CHROMOSOMAL INSTABILITY; CHROMOSOME MOSAICISM; CLINICAL OBSERVATION; COLONY FORMING CELL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MODEL; DISEASE SEVERITY; DNA REPAIR; DRUG RESEARCH; FANCONI ANEMIA; FEMALE; GENE MUTATION; GENE THERAPY; HEMATOLOGIC DISEASE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; INCIDENCE; IONIZING RADIATION; MALE; MOUSE; NONHUMAN; PHENOTYPE; RADIOSENSITIVITY; RECIPIENT; WILD TYPE;

ANIMALS; BONE MARROW CELLS; BRCA2 PROTEIN; CELL PROLIFERATION; CHROMOSOME ABERRATIONS; DISEASE MODELS, ANIMAL; FANCONI ANEMIA; GENE DELETION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC SYSTEM; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MITOMYCIN; MYELOID CELLS; PHENOTYPE;

EID: 33748043345     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2006.05.018     Document Type: Article

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