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Volumn 37, Issue 6, 2009, Pages 1740-1754

A role for monoubiquitinated FANCD2 at telomeres in ALT cells

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; FANCONI ANEMIA GROUP A PROTEIN; FANCONI ANEMIA GROUP D2 PROTEIN; FANCONI ANEMIA GROUP L PROTEIN; SMALL INTERFERING RNA; TELOMERASE; ATR PROTEIN, HUMAN; CELL CYCLE PROTEIN; PROTEIN SERINE THREONINE KINASE; TELOMERIC REPEAT BINDING FACTOR 1;

EID: 64549109258     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkn995     Document Type: Article
Times cited : (73)

References (66)
  • 1
    • 0037439356 scopus 로고    scopus 로고
    • Cancer in Fanconi anemia, 1927-2001
    • Alter,B.P. (2003) Cancer in Fanconi anemia, 1927-2001. Cancer, 97, 425-440.
    • (2003) Cancer , vol.97 , pp. 425-440
    • Alter, B.P.1
  • 2
    • 33744481750 scopus 로고    scopus 로고
    • Molecular pathogenesis of Fanconi anemia: Recent progress
    • Taniguchi,T. and D'Andrea,A.D. (2006) Molecular pathogenesis of Fanconi anemia: Recent progress. Blood, 107, 4223-4233.
    • (2006) Blood , vol.107 , pp. 4223-4233
    • Taniguchi, T.1    D'Andrea, A.D.2
  • 4
    • 25144492769 scopus 로고    scopus 로고
    • Unraveling the Fanconi anemia-DNA repair connection
    • Thompson,L.H. (2005) Unraveling the Fanconi anemia-DNA repair connection. Nat. Genet., 37, 921-922.
    • (2005) Nat. Genet , vol.37 , pp. 921-922
    • Thompson, L.H.1
  • 5
    • 34247577746 scopus 로고    scopus 로고
    • The Fanconi family adds a fraternal twin
    • Grompe,M. and van de Vrugt,H. (2007) The Fanconi family adds a fraternal twin. Dev. Cell, 12, 661-662.
    • (2007) Dev. Cell , vol.12 , pp. 661-662
    • Grompe, M.1    van de Vrugt, H.2
  • 10
    • 4043133287 scopus 로고    scopus 로고
    • ATR couples FANCD2 monoubiquitination to the DNA-damage response
    • Andreassen,P.R., D'Andrea,A.D. and Taniguchi,T. (2004) ATR couples FANCD2 monoubiquitination to the DNA-damage response. Genes Dev., 18, 1958-1963.
    • (2004) Genes Dev , vol.18 , pp. 1958-1963
    • Andreassen, P.R.1    D'Andrea, A.D.2    Taniguchi, T.3
  • 12
    • 0037178761 scopus 로고    scopus 로고
    • Connecting chromosomes, crisis, and cancer
    • Maser,R.S. and DePinho,R.A. (2002) Connecting chromosomes, crisis, and cancer. Science, 297, 565-569.
    • (2002) Science , vol.297 , pp. 565-569
    • Maser, R.S.1    DePinho, R.A.2
  • 14
    • 0037148281 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres in mammalian cells
    • Henson,J.D., Neumann,A.A., Yeager,T.R. and Reddel,R.R. (2002) Alternative lengthening of telomeres in mammalian cells. Oncogene, 21, 598-610.
    • (2002) Oncogene , vol.21 , pp. 598-610
    • Henson, J.D.1    Neumann, A.A.2    Yeager, T.R.3    Reddel, R.R.4
  • 16
    • 0036510162 scopus 로고    scopus 로고
    • Molecular characterization of inter-telomere and intratelomere mutations in human ALT cells
    • Varley,H., Pickett,H.A., Foxon,J.L., Reddel,R.R. and Royle,N.J. (2002) Molecular characterization of inter-telomere and intratelomere mutations in human ALT cells. Nat. Genet., 30, 301-305.
    • (2002) Nat. Genet , vol.30 , pp. 301-305
    • Varley, H.1    Pickett, H.A.2    Foxon, J.L.3    Reddel, R.R.4    Royle, N.J.5
  • 18
    • 1942538563 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres is characterized by high rates of telomeric exchange
    • Londono-Vallejo,J.A., Der-Sarkissian,H., Cazes,L., Bacchetti,S. and Reddel,R.R. (2004) Alternative lengthening of telomeres is characterized by high rates of telomeric exchange. Cancer Res., 64, 2324-2327.
    • (2004) Cancer Res , vol.64 , pp. 2324-2327
    • Londono-Vallejo, J.A.1    Der-Sarkissian, H.2    Cazes, L.3    Bacchetti, S.4    Reddel, R.R.5
  • 20
    • 0037224923 scopus 로고    scopus 로고
    • Telomere-based crisis: Functional differences between telomerase activation and ALT in tumor progression
    • Chang,S., Khoo,C.M., Naylor,M.L., Maser,R.S. and DePinho,R.A. (2003) Telomere-based crisis: Functional differences between telomerase activation and ALT in tumor progression. Genes Dev., 17, 88-100.
    • (2003) Genes Dev , vol.17 , pp. 88-100
    • Chang, S.1    Khoo, C.M.2    Naylor, M.L.3    Maser, R.S.4    DePinho, R.A.5
  • 21
    • 0034503110 scopus 로고    scopus 로고
    • ALTassociated PML bodies are present in viable cells and are enriched in cells in the G(2)/ M phase of the cell cycle
    • Grobelny,J.V., Godwin,A.K. and Broccoli,D. (2000) ALTassociated PML bodies are present in viable cells and are enriched in cells in the G(2)/ M phase of the cell cycle. J. Cell Sci., 113, 4577-4585.
    • (2000) J. Cell Sci , vol.113 , pp. 4577-4585
    • Grobelny, J.V.1    Godwin, A.K.2    Broccoli, D.3
  • 22
    • 0034730633 scopus 로고    scopus 로고
    • NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres
    • Wu,G., Lee,W.H. and Chen,P.L. (2000) NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres. J. Biol. Chem., 275, 30618-30622.
    • (2000) J. Biol. Chem , vol.275 , pp. 30618-30622
    • Wu, G.1    Lee, W.H.2    Chen, P.L.3
  • 24
    • 0037843426 scopus 로고    scopus 로고
    • Assembly of functional ALT-associated promyelocytic leukemia bodies requires Nijmegen Breakage Syndrome 1
    • Wu,G., Jiang,X., Lee,W.H. and Chen,P.L. (2003) Assembly of functional ALT-associated promyelocytic leukemia bodies requires Nijmegen Breakage Syndrome 1. Cancer Res., 63, 2589-2595.
    • (2003) Cancer Res , vol.63 , pp. 2589-2595
    • Wu, G.1    Jiang, X.2    Lee, W.H.3    Chen, P.L.4
  • 26
    • 0033199695 scopus 로고    scopus 로고
    • Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body
    • Yeager,T.R., Neumann,A.A., Englezou,A., Huschtscha,L.I., Noble,J.R. and Reddel,R.R. (1999) Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body. Cancer Res., 59, 4175-4179.
    • (1999) Cancer Res , vol.59 , pp. 4175-4179
    • Yeager, T.R.1    Neumann, A.A.2    Englezou, A.3    Huschtscha, L.I.4    Noble, J.R.5    Reddel, R.R.6
  • 27
    • 37549060645 scopus 로고    scopus 로고
    • Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres
    • Grudic,A., Jul-Larsen,A., Haring,S.J., Wold,M.S., Lonning,P.E., Bjerkvig,R. and Boe,S.O. (2007) Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres. Nucleic Acids Res., 35 7267-7278.
    • (2007) Nucleic Acids Res , vol.35 , pp. 7267-7278
    • Grudic, A.1    Jul-Larsen, A.2    Haring, S.J.3    Wold, M.S.4    Lonning, P.E.5    Bjerkvig, R.6    Boe, S.O.7
  • 28
    • 34447129654 scopus 로고    scopus 로고
    • The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins
    • Potts,P.R. and Yu,H. (2007) The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins. Nat. Struct. Mol. Biol., 14, 581-590.
    • (2007) Nat. Struct. Mol. Biol , vol.14 , pp. 581-590
    • Potts, P.R.1    Yu, H.2
  • 29
    • 0028171096 scopus 로고
    • Microtubule dependency of p34cdc2 inactivation and mitotic exit in mammalian cells
    • Andreassen,P.R. and Margolis,R.L. (1994) Microtubule dependency of p34cdc2 inactivation and mitotic exit in mammalian cells. J. Cell Biol., 127, 789-802.
    • (1994) J. Cell Biol , vol.127 , pp. 789-802
    • Andreassen, P.R.1    Margolis, R.L.2
  • 30
    • 14644391577 scopus 로고    scopus 로고
    • The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability
    • Howlett,N.G., Taniguchi,T., Durkin,S.G., D'Andrea,A.D. and Glover,T.W. (2005) The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability. Hum. Mol. Genet., 14, 693-701.
    • (2005) Hum. Mol. Genet , vol.14 , pp. 693-701
    • Howlett, N.G.1    Taniguchi, T.2    Durkin, S.G.3    D'Andrea, A.D.4    Glover, T.W.5
  • 32
    • 41149099102 scopus 로고    scopus 로고
    • A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis
    • Weber,K., Bartsch,U., Stocking,C. and Fehse,B. (2008) A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis. Mol. Ther., 16, 698-706.
    • (2008) Mol. Ther , vol.16 , pp. 698-706
    • Weber, K.1    Bartsch, U.2    Stocking, C.3    Fehse, B.4
  • 34
    • 3142699748 scopus 로고    scopus 로고
    • Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells
    • Bailey,S.M., Brenneman,M.A. and Goodwin,E.H. (2004) Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells. Nucleic Acids Res., 32, 3743-3751.
    • (2004) Nucleic Acids Res , vol.32 , pp. 3743-3751
    • Bailey, S.M.1    Brenneman, M.A.2    Goodwin, E.H.3
  • 35
    • 0031879115 scopus 로고    scopus 로고
    • Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry
    • Rufer,N., Dragowska,W., Thornbury,G., Roosnek,E. and Lansdorp,P.M. (1998) Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. Nature Biotech., 16, 743-747.
    • (1998) Nature Biotech , vol.16 , pp. 743-747
    • Rufer, N.1    Dragowska, W.2    Thornbury, G.3    Roosnek, E.4    Lansdorp, P.M.5
  • 36
    • 0342561644 scopus 로고    scopus 로고
    • Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
    • Zhu,X.D., Kuster,B., Mann,M., Petrini,J.H. and de Lange,T. (2000) Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres. Nat. Genet., 25, 347-352.
    • (2000) Nat. Genet , vol.25 , pp. 347-352
    • Zhu, X.D.1    Kuster, B.2    Mann, M.3    Petrini, J.H.4    de Lange, T.5
  • 39
    • 2442511752 scopus 로고    scopus 로고
    • Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)
    • Herbig,U., Jobling,W.A., Chen,B.P., Chen,D.J. and Sedivy,J.M. (2004) Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol. Cell, 14, 501-513.
    • (2004) Mol. Cell , vol.14 , pp. 501-513
    • Herbig, U.1    Jobling, W.A.2    Chen, B.P.3    Chen, D.J.4    Sedivy, J.M.5
  • 41
    • 22544466113 scopus 로고    scopus 로고
    • An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres
    • Wang,Y., Erdmann,N., Giannone,R.J., Wu,J., Gomez,M. and Liu,Y. (2005) An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres. Proc. Natl Acad. Sci. USA, 102, 10256-10260.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 10256-10260
    • Wang, Y.1    Erdmann, N.2    Giannone, R.J.3    Wu, J.4    Gomez, M.5    Liu, Y.6
  • 42
    • 33745474120 scopus 로고    scopus 로고
    • Break-induced replication and recombinational telomere elongation in yeast
    • McEachern,M.J. and Haber,J.E. (2006) Break-induced replication and recombinational telomere elongation in yeast. Annu. Rev. Biochem., 75, 111-135.
    • (2006) Annu. Rev. Biochem , vol.75 , pp. 111-135
    • McEachern, M.J.1    Haber, J.E.2
  • 43
    • 25144516017 scopus 로고    scopus 로고
    • Recombination at mammalian telomeres: An alternative mechanism for telomere protection and elongation
    • Tarsounas,M. and West,S.C. (2005) Recombination at mammalian telomeres: an alternative mechanism for telomere protection and elongation. Cell Cycle, 4, 672-674.
    • (2005) Cell Cycle , vol.4 , pp. 672-674
    • Tarsounas, M.1    West, S.C.2
  • 45
    • 2942637828 scopus 로고    scopus 로고
    • The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2
    • Opresko,P.L., Otterlei,M., Graakjaer,J., Bruheim,P., Dawut,L., Kolvraa,S., May,A., Seidman,M.M. and Bohr,V.A. (2004) The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2. Mol. Cell, 14, 763-774.
    • (2004) Mol. Cell , vol.14 , pp. 763-774
    • Opresko, P.L.1    Otterlei, M.2    Graakjaer, J.3    Bruheim, P.4    Dawut, L.5    Kolvraa, S.6    May, A.7    Seidman, M.M.8    Bohr, V.A.9
  • 46
    • 35748968799 scopus 로고    scopus 로고
    • Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres
    • Zhong,Z.H., Jiang,W.Q., Cesare,A.J., Neumann,A.A., Wadhwa,R. and Reddel,R.R. (2007) Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres. J. Biol. Chem., 282, 29314-29322.
    • (2007) J. Biol. Chem , vol.282 , pp. 29314-29322
    • Zhong, Z.H.1    Jiang, W.Q.2    Cesare, A.J.3    Neumann, A.A.4    Wadhwa, R.5    Reddel, R.R.6
  • 47
    • 2942623564 scopus 로고    scopus 로고
    • Localization of hRad9, hHus1, hRad1, and hRad17 and caffeine-sensitive DNA replication at the alternative lengthening of telomeres-associated promyelocytic leukemia body
    • Nabetani,A., Yokoyama,O. and Ishikawa,F. (2004) Localization of hRad9, hHus1, hRad1, and hRad17 and caffeine-sensitive DNA replication at the alternative lengthening of telomeres-associated promyelocytic leukemia body. J. Biol. Chem., 279, 25849-25857.
    • (2004) J. Biol. Chem , vol.279 , pp. 25849-25857
    • Nabetani, A.1    Yokoyama, O.2    Ishikawa, F.3
  • 48
    • 27644443332 scopus 로고    scopus 로고
    • Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway
    • Laud,P.R., Multani,A.S., Bailey,S.M., Wu,L., Ma,J., Kingsley,C., Lebel,M., Pathak,S., DePinho,R.A. and Chang,S. (2005) Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway. Genes Dev., 19, 2560-2570.
    • (2005) Genes Dev , vol.19 , pp. 2560-2570
    • Laud, P.R.1    Multani, A.S.2    Bailey, S.M.3    Wu, L.4    Ma, J.5    Kingsley, C.6    Lebel, M.7    Pathak, S.8    DePinho, R.A.9    Chang, S.10
  • 49
    • 1942437469 scopus 로고    scopus 로고
    • Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice
    • Erdmann,N., Liu,Y. and Harrington,L. (2004) Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice. Proc. Natl Acad. Sci. USA, 101, 6080-6085.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 6080-6085
    • Erdmann, N.1    Liu, Y.2    Harrington, L.3
  • 50
    • 0028007237 scopus 로고
    • Telomere dynamics in an immortal human cell line
    • Murnane,J.P., Sabatier,L., Marder,B.A. and Morgan,W.F. (1994) Telomere dynamics in an immortal human cell line. EMBO J., 13, 4953-4962.
    • (1994) EMBO J , vol.13 , pp. 4953-4962
    • Murnane, J.P.1    Sabatier, L.2    Marder, B.A.3    Morgan, W.F.4
  • 51
    • 34547647631 scopus 로고    scopus 로고
    • DNA damage induces alternative lengthening of telomeres (ALT) associated promyelocytic leukemia bodies that preferentially associate with linear telomeric DNA
    • Fasching,C.L., Neumann,A.A., Muntoni,A., Yeager,T.R. and Reddel,R.R. (2007) DNA damage induces alternative lengthening of telomeres (ALT) associated promyelocytic leukemia bodies that preferentially associate with linear telomeric DNA. Cancer Res., 67, 7072-7077.
    • (2007) Cancer Res , vol.67 , pp. 7072-7077
    • Fasching, C.L.1    Neumann, A.A.2    Muntoni, A.3    Yeager, T.R.4    Reddel, R.R.5
  • 52
    • 33750446640 scopus 로고    scopus 로고
    • POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination
    • He,H., Multani,A.S., Cosme-Blanco,W., Tahara,H., Ma,J., Pathak,S., Deng,Y. and Chang,S. (2006) POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination. EMBO J. 25, 5180-5190.
    • (2006) EMBO J , vol.25 , pp. 5180-5190
    • He, H.1    Multani, A.S.2    Cosme-Blanco, W.3    Tahara, H.4    Ma, J.5    Pathak, S.6    Deng, Y.7    Chang, S.8
  • 60
    • 33746758821 scopus 로고    scopus 로고
    • The Fanconi anemia/BRCA pathway: A coordinator of cross-link repair
    • Mirchandani,K.D. and D'Andrea,A.D. (2006) The Fanconi anemia/BRCA pathway: A coordinator of cross-link repair. Exp. Cell Res., 312, 2647-2653.
    • (2006) Exp. Cell Res , vol.312 , pp. 2647-2653
    • Mirchandani, K.D.1    D'Andrea, A.D.2
  • 62
    • 33746644257 scopus 로고    scopus 로고
    • Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination
    • Celli,G.B., Denchi,E.L. and de Lange,T. (2006) Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination. Nat. Cell Biol., 8, 885-890.
    • (2006) Nat. Cell Biol , vol.8 , pp. 885-890
    • Celli, G.B.1    Denchi, E.L.2    de Lange, T.3
  • 65
    • 0036223483 scopus 로고    scopus 로고
    • Radiosensitivity in Fanconi's anemia patients
    • Alter,B.P. (2002) Radiosensitivity in Fanconi's anemia patients. Radiother. Oncol., 62, 345-347.
    • (2002) Radiother. Oncol , vol.62 , pp. 345-347
    • Alter, B.P.1
  • 66
    • 0141682212 scopus 로고    scopus 로고
    • The evolving role of telomerase inhibitors in the treatment of cancer
    • Mokbel,K. (2003) The evolving role of telomerase inhibitors in the treatment of cancer. Curr. Med. Res. Opin., 19, 470-472.
    • (2003) Curr. Med. Res. Opin , vol.19 , pp. 470-472
    • Mokbel, K.1


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