Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles

Nature Genetics

Volumn 38, Issue 11, 2006, Pages 1239-1241

  Seal, Sheila ^a   Thompson, Deborah ^b   Renwick, Anthony ^a   Elliott, Anna ^a   Kelly, Patrick ^a   Barfoot, Rita ^a   Chagtai, Tasnim ^a   Jayatilake, Hiran ^a   Ahmed, Munaza ^a   Spanova, Katarina ^a   North, Bernard ^a   McGuffog, Lesley ^b   Evans, D Gareth ^c   Eccles, Diana ^d   Easton, Douglas F ^b   Stratton, Michael R ^a,e   Rahman, Nazneen ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c ST MARY S HOSPITAL   (United Kingdom)

^d PRINCESS ANNE HOSPITAL   (United Kingdom)

^e WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; BRIP1 ENZYME; HELICASE; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; BREAST CANCER; CANCER RISK; DNA REPAIR; DNA SEQUENCE; EXON; FAMILY HISTORY; FANCONI ANEMIA; FANCONI ANEMIA J GENE; GEL ELECTROPHORESIS; GENE MUTATION; GENETIC CODE; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; INTRON; MISSENSE MUTATION; ONCOGENE; PRIORITY JOURNAL;

ADULT; BREAST NEOPLASMS; CODON, NONSENSE; DNA-BINDING PROTEINS; FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE DETECTION; HUMANS; MIDDLE AGED; PEDIGREE; PENETRANCE; RNA HELICASES;

EID: 33750465216     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng1902     Document Type: Article

References (15)

1. Antoniou, A.C. & Easton, D.F. Genet. Epidemiol. 21, 1-18 (2001).
2. Cantor, S.B. et al. Cell 105, 149-160 (2001).
3. Cantor, S. et al. Proc. Natl. Acad. Sci. USA 101, 2357-2362 (2004).
4. Peng, M. et al. Oncogene 25, 2245-2253 (2006).
5. Cantor, S.B. & Andreassen, P.R. Cell Cycle 5, 164-167 (2006).
6. Meijers-Heijboer, H. et al. Nat. Genet. 31, 55-59 (2002).
7. Renwick, A. et al. Nat. Genet. 38, 873-875 (2006).
8. Levitus, M. et al. Nat. Genet. 37, 934-935 (2005).
9. Levran, O. et al. Nat. Genet. 37, 931-933 (2005).
10. Litman, R. et al. Cancer Cell 8, 255-265 (2005).
11. Howlett, N.G. et al. Science 297, 606-609 (2002).
12. Taniguchi, T. & D'Andrea, A.D. Blood 107, 4223-4233 (2006).
13. Swift, M. et al. J. Natl. Cancer Inst. 65, 863-867 (1980).
14. Seal, S. et al. Cancer Res. 63, 8596-8599 (2003).
15. Reid, S. et al. J. Med. Genet. 42, 147-151 (2005).