-
1
-
-
0023923035
-
Inhibition of DNA polymerase alpha by aphidicolin derivatives
-
Arabshahi L, Brown N, Khan N, Wright G (1988) Inhibition of DNA polymerase alpha by aphidicolin derivatives. Nucleic Acids Res 16: 5107-5113
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 5107-5113
-
-
Arabshahi, L.1
Brown, N.2
Khan, N.3
Wright, G.4
-
2
-
-
0017118656
-
Susceptibility of Fanconi's anaemia fibroblasts to chromosome damage by carcinogens
-
Auerbach AD, Wolman SR (1976) Susceptibility of Fanconi's anaemia fibroblasts to chromosome damage by carcinogens. Nature 261: 494-496
-
(1976)
Nature
, vol.261
, pp. 494-496
-
-
Auerbach, A.D.1
Wolman, S.R.2
-
3
-
-
32944458421
-
The human RNA surveillance factor UPF1 is required for S phase progression and genome stability
-
Azzalin CM, Lingner J (2006) The human RNA surveillance factor UPF1 is required for S phase progression and genome stability. Curr Biol 16: 433-439
-
(2006)
Curr Biol
, vol.16
, pp. 433-439
-
-
Azzalin, C.M.1
Lingner, J.2
-
4
-
-
36549040859
-
The selectivity of protein kinase inhibitors: A further update
-
Bain J, Plater L, Elliott M, Shpiro N, Hastie CJ, McLauchlan H, Klevernic I, Arthur JS, Alessi DR, Cohen P (2007) The selectivity of protein kinase inhibitors: a further update. Biochem J 408: 297-315
-
(2007)
Biochem J
, vol.408
, pp. 297-315
-
-
Bain, J.1
Plater, L.2
Elliott, M.3
Shpiro, N.4
Hastie, C.J.5
McLauchlan, H.6
Klevernic, I.7
Arthur, J.S.8
Alessi, D.R.9
Cohen, P.10
-
5
-
-
69449102249
-
Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M
-
Bakker ST, van de Vrugt HJ, Rooimans MA, Oostra AB, Steltenpool J, Delzenne-Goette E, van der Wal A, van der Valk M, Joenje H, Te Riele H, de Winter JP (2009) Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M. Hum Mol Genet 18: 3484-3495
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3484-3495
-
-
Bakker, S.T.1
Van De Vrugt, H.J.2
Rooimans, M.A.3
Oostra, A.B.4
Steltenpool, J.5
Delzenne-Goette, E.6
Van Der Wal, A.7
Van Der Valk, M.8
Joenje, H.9
Te Riele, H.10
De Winter, J.P.11
-
6
-
-
0042466524
-
DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1
-
Cobb JA, Bjergbaek L, Shimada K, Frei C, Gasser SM (2003) DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. EMBO J 22: 4325-4336
-
(2003)
EMBO J
, vol.22
, pp. 4325-4336
-
-
Cobb, J.A.1
Bjergbaek, L.2
Shimada, K.3
Frei, C.4
Gasser, S.M.5
-
7
-
-
34047115860
-
HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability
-
Collis SJ, Barber LJ, Clark AJ, Martin JS, Ward JD, Boulton SJ (2007) HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability. Nat Cell Biol 9: 391-401
-
(2007)
Nat Cell Biol
, vol.9
, pp. 391-401
-
-
Collis, S.J.1
Barber, L.J.2
Clark, A.J.3
Martin, J.S.4
Ward, J.D.5
Boulton, S.J.6
-
8
-
-
55049111236
-
FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the fanconi anemia core complex
-
Collis SJ, Ciccia A, Deans AJ, Horejsi Z, Martin JS, Maslen SL, Skehel JM, Elledge SJ, West SC, Boulton SJ (2008) FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the fanconi anemia core complex. Mol Cell 32: 313-324
-
(2008)
Mol Cell
, vol.32
, pp. 313-324
-
-
Collis, S.J.1
Ciccia, A.2
Deans, A.J.3
Horejsi, Z.4
Martin, J.S.5
Maslen, S.L.6
Skehel, J.M.7
Elledge, S.J.8
West, S.C.9
Boulton, S.J.10
-
9
-
-
0037436108
-
DNA damage-induced replication fork regression and processing in Escherichia coli
-
Courcelle J, Donaldson JR, Chow KH, Courcelle CT (2003) DNA damage-induced replication fork regression and processing in Escherichia coli. Science 299: 1064-1067
-
(2003)
Science
, vol.299
, pp. 1064-1067
-
-
Courcelle, J.1
Donaldson, J.R.2
Chow, K.H.3
Courcelle, C.T.4
-
10
-
-
40649097306
-
Activation of ubiquitin-dependent DNA damage bypass is mediated by replication protein a
-
Davies AA, Huttner D, Daigaku Y, Chen S, Ulrich HD (2008) Activation of ubiquitin-dependent DNA damage bypass is mediated by replication protein a. Mol Cell 29: 625-636
-
(2008)
Mol Cell
, vol.29
, pp. 625-636
-
-
Davies, A.A.1
Huttner, D.2
Daigaku, Y.3
Chen, S.4
Ulrich, H.D.5
-
12
-
-
0035105291
-
Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway
-
Garcia-Higuera I, Taniguchi T, Ganesan S, Meyn MS, Timmers C, Hejna J, Grompe M, D'Andrea AD (2001) Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol Cell 7: 249-262
-
(2001)
Mol Cell
, vol.7
, pp. 249-262
-
-
Garcia-Higuera, I.1
Taniguchi, T.2
Ganesan, S.3
Meyn, M.S.4
Timmers, C.5
Hejna, J.6
Grompe, M.7
D'Andrea, A.D.8
-
13
-
-
55849133052
-
Remodeling of DNA replication structures by the branch point translocase FANCM
-
Gari K, Decaillet C, Delannoy M, Wu L, Constantinou A (2008a) Remodeling of DNA replication structures by the branch point translocase FANCM. Proc Natl Acad Sci USA 105: 16107-16112
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 16107-16112
-
-
Gari, K.1
Decaillet, C.2
Delannoy, M.3
Wu, L.4
Constantinou, A.5
-
14
-
-
38349050087
-
The Fanconi anemia protein FANCM can promote branch migration of Holliday junctions and replication forks
-
Gari K, Decaillet C, Stasiak AZ, Stasiak A, Constantinou A (2008b) The Fanconi anemia protein FANCM can promote branch migration of Holliday junctions and replication forks. Mol Cell 29: 141-148
-
(2008)
Mol Cell
, vol.29
, pp. 141-148
-
-
Gari, K.1
Decaillet, C.2
Stasiak, A.Z.3
Stasiak, A.4
Constantinou, A.5
-
15
-
-
0022505598
-
The C-C (6-4) UV photoproduct is mutagenic in Escherichia coli
-
Glickman BW, Schaaper RM, Haseltine WA, Dunn RL, Brash DE (1986) The C-C (6-4) UV photoproduct is mutagenic in Escherichia coli. Proc Natl Acad Sci USA 83: 6945-6949
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 6945-6949
-
-
Glickman, B.W.1
Schaaper, R.M.2
Haseltine, W.A.3
Dunn, R.L.4
Brash, D.E.5
-
16
-
-
33845330910
-
Replisome assembly and the direct restart of stalled replication forks
-
Heller RC, Marians KJ (2006) Replisome assembly and the direct restart of stalled replication forks. Nat Rev Mol Cell Biol 7: 932-943
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 932-943
-
-
Heller, R.C.1
Marians, K.J.2
-
17
-
-
0038298811
-
XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes
-
Henry-Mowatt J, Jackson D, Masson JY, Johnson PA, Clements PM, Benson FE, Thompson LH, Takeda S, West SC, Caldecott KW (2003) XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes. Mol Cell 11: 1109-1117
-
(2003)
Mol Cell
, vol.11
, pp. 1109-1117
-
-
Henry-Mowatt, J.1
Jackson, D.2
Masson, J.Y.3
Johnson, P.A.4
Clements, P.M.5
Benson, F.E.6
Thompson, L.H.7
Takeda, S.8
West, S.C.9
Caldecott, K.W.10
-
18
-
-
65549153598
-
Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase
-
Indiani C, Langston LD, Yurieva O, Goodman MF, O'Donnell M (2009) Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase. Proc Natl Acad Sci USA 106: 6031-6038
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 6031-6038
-
-
Indiani, C.1
Langston, L.D.2
Yurieva, O.3
Goodman, M.F.4
O'Donnell, M.5
-
19
-
-
0032559794
-
Replicon clusters are stable units of chromosome structure: Evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells
-
Jackson DA, Pombo A (1998) Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells. J Cell Biol 140: 1285-1295
-
(1998)
J Cell Biol
, vol.140
, pp. 1285-1295
-
-
Jackson, D.A.1
Pombo, A.2
-
20
-
-
61849128915
-
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis
-
Kee Y, Kim JM, D'Andrea AD (2009) Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. Genes Dev 23: 555-560
-
(2009)
Genes Dev
, vol.23
, pp. 555-560
-
-
Kee, Y.1
Kim, J.M.2
D'Andrea, A.D.3
-
21
-
-
46749106037
-
Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24
-
Kim JM, Kee Y, Gurtan A, D'Andrea AD (2008) Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24. Blood 111: 5215-5222
-
(2008)
Blood
, vol.111
, pp. 5215-5222
-
-
Kim, J.M.1
Kee, Y.2
Gurtan, A.3
D'Andrea, A.D.4
-
22
-
-
0037228519
-
The protein kinase C inhibitor Go6976 is a potent inhibitor of DNA damage-induced S and G2 cell cycle checkpoints
-
Kohn EA, Yoo CJ, Eastman A (2003) The protein kinase C inhibitor Go6976 is a potent inhibitor of DNA damage-induced S and G2 cell cycle checkpoints. Cancer Res 63: 31-35
-
(2003)
Cancer Res
, vol.63
, pp. 31-35
-
-
Kohn, E.A.1
Yoo, C.J.2
Eastman, A.3
-
23
-
-
34447509295
-
Antitumour drugs impede DNA uncoiling by topoisomerase i
-
Koster DA, Palle K, Bot ES, Bjornsti MA, Dekker NH (2007) Antitumour drugs impede DNA uncoiling by topoisomerase I. Nature 448: 213-217
-
(2007)
Nature
, vol.448
, pp. 213-217
-
-
Koster, D.A.1
Palle, K.2
Bot, E.S.3
Bjornsti, M.A.4
Dekker, N.H.5
-
24
-
-
0029863952
-
Human DNA topoisomerase I-mediated cleavages stimulated by ultraviolet light-induced DNA damage
-
Lanza A, Tornaletti S, Rodolfo C, Scanavini MC, Pedrini AM (1996) Human DNA topoisomerase I-mediated cleavages stimulated by ultraviolet light-induced DNA damage. J Biol Chem 271: 6978-6986
-
(1996)
J Biol Chem
, vol.271
, pp. 6978-6986
-
-
Lanza, A.1
Tornaletti, S.2
Rodolfo, C.3
Scanavini, M.C.4
Pedrini, A.M.5
-
25
-
-
64049087591
-
Fork regression is an active helicase-driven pathway in bacteriophage T4
-
Long DT, Kreuzer KN (2009) Fork regression is an active helicase-driven pathway in bacteriophage T4. EMBO Rep 10: 394-399
-
(2009)
EMBO Rep
, vol.10
, pp. 394-399
-
-
Long, D.T.1
Kreuzer, K.N.2
-
26
-
-
29544437558
-
Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions
-
Lopes M, Foiani M, Sogo JM (2006) Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions. Mol Cell 21: 15-27
-
(2006)
Mol Cell
, vol.21
, pp. 15-27
-
-
Lopes, M.1
Foiani, M.2
Sogo, J.M.3
-
27
-
-
25144449181
-
A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M
-
Meetei AR, Medhurst AL, Ling C, Xue Y, Singh TR, Bier P, Steltenpool J, Stone S, Dokal I, Mathew CG, Hoatlin M, Joenje H, de Winter JP, Wang W (2005) A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M. Nat Genet 37: 958-963
-
(2005)
Nat Genet
, vol.37
, pp. 958-963
-
-
Meetei, A.R.1
Medhurst, A.L.2
Ling, C.3
Xue, Y.4
Singh, T.R.5
Bier, P.6
Steltenpool, J.7
Stone, S.8
Dokal, I.9
Mathew, C.G.10
Hoatlin, M.11
Joenje, H.12
De Winter, J.P.13
Wang, W.14
-
28
-
-
33749034730
-
Topoisomerase i inhibitors: Camptothecins and beyond
-
Pommier Y (2006) Topoisomerase I inhibitors: camptothecins and beyond. Nat Rev Cancer 6: 789-802
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 789-802
-
-
Pommier, Y.1
-
29
-
-
0035902590
-
Topological challenges to DNA replication: Conformations at the fork
-
Postow L, Crisona NJ, Peter BJ, Hardy CD, Cozzarelli NR (2001a) Topological challenges to DNA replication: conformations at the fork. Proc Natl Acad Sci USA 98: 8219-8226
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8219-8226
-
-
Postow, L.1
Crisona, N.J.2
Peter, B.J.3
Hardy, C.D.4
Cozzarelli, N.R.5
-
30
-
-
0035951787
-
Positive torsional strain causes the formation of a four-way junction at replication forks
-
Postow L, Ullsperger C, Keller RW, Bustamante C, Vologodskii AV, Cozzarelli NR (2001b) Positive torsional strain causes the formation of a four-way junction at replication forks. J Biol Chem 276: 2790-2796
-
(2001)
J Biol Chem
, vol.276
, pp. 2790-2796
-
-
Postow, L.1
Ullsperger, C.2
Keller, R.W.3
Bustamante, C.4
Vologodskii, A.V.5
Cozzarelli, N.R.6
-
32
-
-
67949085157
-
The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair
-
Rosado IV, Niedzwiedz W, Alpi AF, Patel KJ (2009) The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair. Nucleic Acids Res 37: 4360-4370
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 4360-4370
-
-
Rosado, I.V.1
Niedzwiedz, W.2
Alpi, A.F.3
Patel, K.J.4
-
33
-
-
0013772684
-
Spontaneous chromosome aberrations in familial panmyelopathy
-
Schroeder TM, Anschutz F, Knopp A (1964) Spontaneous chromosome aberrations in familial panmyelopathy. Humangenetik 1: 194-196
-
(1964)
Humangenetik
, vol.1
, pp. 194-196
-
-
Schroeder, T.M.1
Anschutz, F.2
Knopp, A.3
-
34
-
-
67649635974
-
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
-
Sfeir A, Kosiyatrakul ST, Hockemeyer D, MacRae SL, Karlseder J, Schildkraut CL, de Lange T (2009) Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication. Cell 138: 90-103
-
(2009)
Cell
, vol.138
, pp. 90-103
-
-
Sfeir, A.1
Kosiyatrakul, S.T.2
Hockemeyer, D.3
MacRae, S.L.4
Karlseder, J.5
Schildkraut, C.L.6
De Lange, T.7
-
35
-
-
67650569540
-
Impaired FANCD2 monoubiquitina-tion and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M
-
Singh TR, Bakker ST, Agarwal S, Jansen M, Grassman E, Godthelp BC, Ali AM, Du CH, Rooimans MA, Fan Q, Wahengbam K, Steltenpool J, Andreassen PR, Williams DA, Joenje H, de Winter JP, Meetei AR (2009) Impaired FANCD2 monoubiquitina-tion and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M. Blood 114: 174-180
-
(2009)
Blood
, vol.114
, pp. 174-180
-
-
Singh, T.R.1
Bakker, S.T.2
Agarwal, S.3
Jansen, M.4
Grassman, E.5
Godthelp, B.C.6
Ali, A.M.7
Du, C.H.8
Rooimans, M.A.9
Fan, Q.10
Wahengbam, K.11
Steltenpool, J.12
Andreassen, P.R.13
Williams, D.A.14
Joenje, H.15
De Winter, J.P.16
Meetei, A.R.17
-
36
-
-
34247110291
-
Identification of the FANCI protein, a mono-ubiquitinated FANCD2 paralog required for DNA repair
-
Smogorzewska A, Matsuoka S, Vinciguerra P, McDonald III ER, Hurov KE, Luo J, Ballif BA, Gygi SP, Hofmann K, D'Andrea AD, Elledge SJ (2007) Identification of the FANCI protein, a mono-ubiquitinated FANCD2 paralog required for DNA repair. Cell 129: 289-301
-
(2007)
Cell
, vol.129
, pp. 289-301
-
-
Smogorzewska, A.1
Matsuoka, S.2
Vinciguerra, P.3
McDonald Iii, E.R.4
Hurov, K.E.5
Luo, J.6
Ballif, B.A.7
Gygi, S.P.8
Hofmann, K.9
D'Andrea, A.D.10
Elledge, S.J.11
-
37
-
-
0037178740
-
Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
-
Sogo JM, Lopes M, Foiani M (2002) Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects. Science 297: 599-602
-
(2002)
Science
, vol.297
, pp. 599-602
-
-
Sogo, J.M.1
Lopes, M.2
Foiani, M.3
-
38
-
-
59449101071
-
PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA
-
Sugimura K, Takebayashi S, Taguchi H, Takeda S, Okumura K (2008) PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA. J Cell Biol 183: 1203-1212
-
(2008)
J Cell Biol
, vol.183
, pp. 1203-1212
-
-
Sugimura, K.1
Takebayashi, S.2
Taguchi, H.3
Takeda, S.4
Okumura, K.5
-
39
-
-
53149087431
-
The FANCM ortholog Fml1 promotes recombination at stalled replication forks and limits crossing over during DNA double-strand break repair
-
Sun W, Nandi S, Osman F, Ahn JS, Jakovleska J, Lorenz A, Whitby MC (2008) The FANCM ortholog Fml1 promotes recombination at stalled replication forks and limits crossing over during DNA double-strand break repair. Mol Cell 32: 118-128
-
(2008)
Mol Cell
, vol.32
, pp. 118-128
-
-
Sun, W.1
Nandi, S.2
Osman, F.3
Ahn, J.S.4
Jakovleska, J.5
Lorenz, A.6
Whitby, M.C.7
-
41
-
-
34249935010
-
Maintenance of fork integrity at damaged DNA and natural pause sites
-
Tourriere H, Pasero P (2007) Maintenance of fork integrity at damaged DNA and natural pause sites. DNA Repair (Amst) 6: 900-913
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 900-913
-
-
Tourriere, H.1
Pasero, P.2
-
42
-
-
0037484271
-
Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents
-
Xiao Z, Chen Z, Gunasekera AH, Sowin TJ, Rosenberg SH, Fesik S, Zhang H (2003) Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents. J Biol Chem 278: 21767-21773
-
(2003)
J Biol Chem
, vol.278
, pp. 21767-21773
-
-
Xiao, Z.1
Chen, Z.2
Gunasekera, A.H.3
Sowin, T.J.4
Rosenberg, S.H.5
Fesik, S.6
Zhang, H.7
-
43
-
-
44349174992
-
FANCM of the Fanconi anemia core complex is required for both monoubiquitination and DNA repair
-
Xue Y, Li Y, Guo R, Ling C, Wang W (2008) FANCM of the Fanconi anemia core complex is required for both monoubiquitination and DNA repair. Hum Mol Genet 17: 1641-1652
-
(2008)
Hum Mol Genet
, vol.17
, pp. 1641-1652
-
-
Xue, Y.1
Li, Y.2
Guo, R.3
Ling, C.4
Wang, W.5
-
44
-
-
55849133733
-
Identification of SCF ubiquitin ligase substrates by global protein stability profiling
-
Yen HC, Elledge SJ (2008) Identification of SCF ubiquitin ligase substrates by global protein stability profiling. Science 322: 923-929
-
(2008)
Science
, vol.322
, pp. 923-929
-
-
Yen, H.C.1
Elledge, S.J.2
-
45
-
-
24044476837
-
Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway
-
Zhang YW, Otterness DM, Chiang GG, Xie W, Liu YC, Mercurio F, Abraham RT (2005) Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway. Mol Cell 19: 607-618
-
(2005)
Mol Cell
, vol.19
, pp. 607-618
-
-
Zhang, Y.W.1
Otterness, D.M.2
Chiang, G.G.3
Xie, W.4
Liu, Y.C.5
Mercurio, F.6
Abraham, R.T.7
|