Deficiency of UBE2T, the E2Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia

Cell Reports

Volumn 12, Issue 1, 2015, Pages 35-41

  Rickman, Kimberly A ^a   Lach, Francis P ^a   Abhyankar, Avinash ^b   Donovan, Frank X ^c   Sanborn, Erica M ^a   Kennedy, Jennifer A ^a   Sougnez, Carrie ^d   Gabriel, Stacey B ^d   Elemento, Olivier ^e   Chandrasekharappa, Settara C ^c   Schindler, Detlev ^f   Auerbach, Arleen D ^a   Smogorzewska, Agata ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b NEW YORK GENOME CENTER   (United States)

^c NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

^f UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FANCONI ANEMIA GROUP D2 PROTEIN; FANCONI ANEMIA GROUP I PROTEIN; FANCONI ANEMIA PROTEIN; MITOMYCIN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN CONJUGATING ENZYME UBE2T; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; FANCD2 PROTEIN, HUMAN; FANCL PROTEIN, HUMAN; FANCONI ANEMIA GROUP L PROTEIN; PROTEIN BINDING; UBE2T PROTEIN, HUMAN;

ARTICLE; BONE MARROW DEPRESSION; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DNA CROSS LINKING; DNA REPAIR; ENZYME DEFICIENCY; FANCONI ANEMIA; FIBROBLAST; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; UBIQUITINATION; DEFICIENCY; GENE DELETION; GENETICS; HEK293 CELL LINE; METABOLISM;

FANCONI ANEMIA; FANCONI ANEMIA COMPLEMENTATION GROUP D2 PROTEIN; FANCONI ANEMIA COMPLEMENTATION GROUP L PROTEIN; FIBROBLASTS; GENE DELETION; HEK293 CELLS; HUMANS; PROTEIN BINDING; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINATION;

EID: 84937525461     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.06.014     Document Type: Article

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