-
1
-
-
18244384051
-
Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease
-
Adlard P.A., Perreau V.M., Pop V., Cotman C.W. Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease. J. Neurosci. 2005, 25:4217-4221.
-
(2005)
J. Neurosci.
, vol.25
, pp. 4217-4221
-
-
Adlard, P.A.1
Perreau, V.M.2
Pop, V.3
Cotman, C.W.4
-
2
-
-
79952610782
-
Metal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer's disease
-
Adlard P.A., Bica L., White A.R., Nurjono M., Filiz G., Crouch P.J., Donnelly P.S., Cappai R., Finkelstein D.I., Bush A.I. Metal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer's disease. PLoS One 2011, 6:e17669.
-
(2011)
PLoS One
, vol.6
, pp. e17669
-
-
Adlard, P.A.1
Bica, L.2
White, A.R.3
Nurjono, M.4
Filiz, G.5
Crouch, P.J.6
Donnelly, P.S.7
Cappai, R.8
Finkelstein, D.I.9
Bush, A.I.10
-
3
-
-
84926688499
-
Insulin improves memory and reduces chronic neuroinflammation in the hippocampus of young but not aged brains
-
Adzovic L., Lynn A.E., D'Angelo H.M., Crockett A.M., Kaercher R.M., Royer S.E., Hopp S.C., Wenk G.L. Insulin improves memory and reduces chronic neuroinflammation in the hippocampus of young but not aged brains. J. Neuroinflammation 2015, 12:63.
-
(2015)
J. Neuroinflammation
, vol.12
, pp. 63
-
-
Adzovic, L.1
Lynn, A.E.2
D'Angelo, H.M.3
Crockett, A.M.4
Kaercher, R.M.5
Royer, S.E.6
Hopp, S.C.7
Wenk, G.L.8
-
4
-
-
0001159822
-
Are new neurons formed in the brains of adult mammals?
-
Altman J. Are new neurons formed in the brains of adult mammals?. Science 1962, 135:1127-1128.
-
(1962)
Science
, vol.135
, pp. 1127-1128
-
-
Altman, J.1
-
5
-
-
41149170762
-
Physical exercise at midlife and risk of dementia three decades later: a population-based study of Swedish twins
-
Andel R., Crowe M., Pedersen N.L., Fratiglioni L., Johansson B., Gatz M. Physical exercise at midlife and risk of dementia three decades later: a population-based study of Swedish twins. J. Gerontol. Ser. A Biol. Sci. Med. Sci. 2008, 63:62-66.
-
(2008)
J. Gerontol. Ser. A Biol. Sci. Med. Sci.
, vol.63
, pp. 62-66
-
-
Andel, R.1
Crowe, M.2
Pedersen, N.L.3
Fratiglioni, L.4
Johansson, B.5
Gatz, M.6
-
6
-
-
4043147336
-
Environmental enrichment improves cognition in aged Alzheimer's transgenic mice despite stable beta-amyloid deposition
-
Arendash G.W., Garcia M.F., Costa D.A., Cracchiolo J.R., Wefes I.M., Potter H. Environmental enrichment improves cognition in aged Alzheimer's transgenic mice despite stable beta-amyloid deposition. Neuroreport 2004, 15:1751-1754.
-
(2004)
Neuroreport
, vol.15
, pp. 1751-1754
-
-
Arendash, G.W.1
Garcia, M.F.2
Costa, D.A.3
Cracchiolo, J.R.4
Wefes, I.M.5
Potter, H.6
-
7
-
-
84864237721
-
Early stage drug treatment that normalizes proinflammatory cytokine production attenuates synaptic dysfunction in a mouse model that exhibits age-dependent progression of Alzheimer's disease-related pathology
-
Bachstetter A.D., Norris C.M., Sompol P., Wilcock D.M., Goulding D., Neltner J.H., St Clair D., Watterson D.M., Van Eldik L.J. Early stage drug treatment that normalizes proinflammatory cytokine production attenuates synaptic dysfunction in a mouse model that exhibits age-dependent progression of Alzheimer's disease-related pathology. J. Neurosci. 2012, 32:10201-10210.
-
(2012)
J. Neurosci.
, vol.32
, pp. 10201-10210
-
-
Bachstetter, A.D.1
Norris, C.M.2
Sompol, P.3
Wilcock, D.M.4
Goulding, D.5
Neltner, J.H.6
St Clair, D.7
Watterson, D.M.8
Van Eldik, L.J.9
-
8
-
-
79958241817
-
Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology
-
Belarbi K., Burnouf S., Fernandez-Gomez F.J., Laurent C., Lestavel S., Figeac M., Sultan A., Troquier L., Leboucher A., Caillierez R., Grosjean M.E., Demeyer D., Obriot H., Brion I., Barbot B., Galas M.C., Staels B., Humez S., Sergeant N., Schraen-Maschke S., Muhr-Tailleux A., Hamdane M., Buee L., Blum D. Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology. Neurobiol. Dis. 2011, 43:486-494.
-
(2011)
Neurobiol. Dis.
, vol.43
, pp. 486-494
-
-
Belarbi, K.1
Burnouf, S.2
Fernandez-Gomez, F.J.3
Laurent, C.4
Lestavel, S.5
Figeac, M.6
Sultan, A.7
Troquier, L.8
Leboucher, A.9
Caillierez, R.10
Grosjean, M.E.11
Demeyer, D.12
Obriot, H.13
Brion, I.14
Barbot, B.15
Galas, M.C.16
Staels, B.17
Humez, S.18
Sergeant, N.19
Schraen-Maschke, S.20
Muhr-Tailleux, A.21
Hamdane, M.22
Buee, L.23
Blum, D.24
more..
-
9
-
-
47249123640
-
Intrahippocampal transplantation of transgenic neural precursor cells overexpressing interleukin-1 receptor antagonist blocks chronic isolation-induced impairment in memory and neurogenesis
-
Ben Menachem-Zidon O., Goshen I., Kreisel T., Ben Menahem Y., Reinhartz E., Ben Hur T., Yirmiya R. Intrahippocampal transplantation of transgenic neural precursor cells overexpressing interleukin-1 receptor antagonist blocks chronic isolation-induced impairment in memory and neurogenesis. Neuropsychopharmacology 2008, 33:2251-2262.
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 2251-2262
-
-
Ben Menachem-Zidon, O.1
Goshen, I.2
Kreisel, T.3
Ben Menahem, Y.4
Reinhartz, E.5
Ben Hur, T.6
Yirmiya, R.7
-
10
-
-
84890565652
-
Intra-hippocampal transplantation of neural precursor cells with transgenic over-expression of IL-1 receptor antagonist rescues memory and neurogenesis impairments in an Alzheimer's disease model
-
Ben-Menachem-Zidon O., Ben-Menahem Y., Ben-Hur T., Yirmiya R. Intra-hippocampal transplantation of neural precursor cells with transgenic over-expression of IL-1 receptor antagonist rescues memory and neurogenesis impairments in an Alzheimer's disease model. Neuropsychopharmacology 2014, 39:401-414.
-
(2014)
Neuropsychopharmacology
, vol.39
, pp. 401-414
-
-
Ben-Menachem-Zidon, O.1
Ben-Menahem, Y.2
Ben-Hur, T.3
Yirmiya, R.4
-
11
-
-
84961289175
-
Exercise but not (-)-epigallocatechin-3-gallate or beta-alanine enhances physical fitness, brain plasticity, and behavioral performance in mice
-
Bhattacharya T.K., Pence B.D., Ossyra J.M., Gibbons T.E., Perez S., McCusker R.H., Kelley K.W., Johnson R.W., Woods J.A., Rhodes J.S. Exercise but not (-)-epigallocatechin-3-gallate or beta-alanine enhances physical fitness, brain plasticity, and behavioral performance in mice. Physiol. Behav. 2015, 145:29-37.
-
(2015)
Physiol. Behav.
, vol.145
, pp. 29-37
-
-
Bhattacharya, T.K.1
Pence, B.D.2
Ossyra, J.M.3
Gibbons, T.E.4
Perez, S.5
McCusker, R.H.6
Kelley, K.W.7
Johnson, R.W.8
Woods, J.A.9
Rhodes, J.S.10
-
12
-
-
84862088615
-
Inhibition of microglial activation protects hippocampal neurogenesis and improves cognitive deficits in a transgenic mouse model for Alzheimer's disease
-
Biscaro B., Lindvall O., Tesco G., Ekdahl C.T., Nitsch R.M. Inhibition of microglial activation protects hippocampal neurogenesis and improves cognitive deficits in a transgenic mouse model for Alzheimer's disease. Neuro-degener. Dis. 2012, 9:187-198.
-
(2012)
Neuro-degener. Dis.
, vol.9
, pp. 187-198
-
-
Biscaro, B.1
Lindvall, O.2
Tesco, G.3
Ekdahl, C.T.4
Nitsch, R.M.5
-
13
-
-
0025180876
-
Learning causes synaptogenesis, whereas motor activity causes angiogenesis, in cerebellar cortex of adult rats
-
Black J.E., Isaacs K.R., Anderson B.J., Alcantara A.A., Greenough W.T. Learning causes synaptogenesis, whereas motor activity causes angiogenesis, in cerebellar cortex of adult rats. Proc. Natl. Acad. Sci. U. S. A. 1990, 87:5568-5572.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 5568-5572
-
-
Black, J.E.1
Isaacs, K.R.2
Anderson, B.J.3
Alcantara, A.A.4
Greenough, W.T.5
-
14
-
-
78149414428
-
Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting Abeta and tau pathologies in 3xTg-aD mice
-
Blanchard J., Wanka L., Tung Y.C., Cardenas-Aguayo Mdel C., LaFerla F.M., Iqbal K., Grundke-Iqbal I. Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting Abeta and tau pathologies in 3xTg-aD mice. Acta Neuropathol. (Berl.) 2010, 120:605-621.
-
(2010)
Acta Neuropathol. (Berl.)
, vol.120
, pp. 605-621
-
-
Blanchard, J.1
Wanka, L.2
Tung, Y.C.3
Cardenas-Aguayo Mdel, C.4
LaFerla, F.M.5
Iqbal, K.6
Grundke-Iqbal, I.7
-
15
-
-
84953210392
-
Exercise-induced neuroprotection of hippocampus in APP/PS1 transgenic mice via upregulation of mitochondrial 8-oxoguanine DNA glycosylase
-
Bo H., Kang W., Jiang N., Wang X., Zhang Y., Ji L.L. Exercise-induced neuroprotection of hippocampus in APP/PS1 transgenic mice via upregulation of mitochondrial 8-oxoguanine DNA glycosylase. Oxid. Med. Cell. Longev. 2014, 2014:834502.
-
(2014)
Oxid. Med. Cell. Longev.
, vol.2014
, pp. 834502
-
-
Bo, H.1
Kang, W.2
Jiang, N.3
Wang, X.4
Zhang, Y.5
Ji, L.L.6
-
16
-
-
84901036284
-
Impact of indomethacin on neuroinflammation and hippocampal neurogenesis in aged mice
-
Boehme M., Guenther M., Stahr A., Liebmann M., Jaenisch N., Witte O.W., Frahm C. Impact of indomethacin on neuroinflammation and hippocampal neurogenesis in aged mice. Neurosci. Lett. 2014, 572:7-12.
-
(2014)
Neurosci. Lett.
, vol.572
, pp. 7-12
-
-
Boehme, M.1
Guenther, M.2
Stahr, A.3
Liebmann, M.4
Jaenisch, N.5
Witte, O.W.6
Frahm, C.7
-
17
-
-
33748790666
-
Increased proliferation reflects glial and vascular-associated changes, but not neurogenesis in the presenile Alzheimer hippocampus
-
Boekhoorn K., Joels M., Lucassen P.J. Increased proliferation reflects glial and vascular-associated changes, but not neurogenesis in the presenile Alzheimer hippocampus. Neurobiol. Dis. 2006, 24:1-14.
-
(2006)
Neurobiol. Dis.
, vol.24
, pp. 1-14
-
-
Boekhoorn, K.1
Joels, M.2
Lucassen, P.J.3
-
18
-
-
84866030690
-
Hippocampal angiogenesis and progenitor cell proliferation are increased with antidepressant use in major depression
-
Boldrini M., Hen R., Underwood M.D., Rosoklija G.B., Dwork A.J., Mann J.J., Arango V. Hippocampal angiogenesis and progenitor cell proliferation are increased with antidepressant use in major depression. Biol. Psychiatry 2012, 72:562-571.
-
(2012)
Biol. Psychiatry
, vol.72
, pp. 562-571
-
-
Boldrini, M.1
Hen, R.2
Underwood, M.D.3
Rosoklija, G.B.4
Dwork, A.J.5
Mann, J.J.6
Arango, V.7
-
19
-
-
84902113351
-
Rescue of cognitive-aging by administration of a neurogenic and/or neurotrophic compound
-
Bolognin S., Buffelli M., Puolivali J., Iqbal K. Rescue of cognitive-aging by administration of a neurogenic and/or neurotrophic compound. Neurobiol. Aging 2014, 35:2134-2146.
-
(2014)
Neurobiol. Aging
, vol.35
, pp. 2134-2146
-
-
Bolognin, S.1
Buffelli, M.2
Puolivali, J.3
Iqbal, K.4
-
20
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
Borchelt D.R., Ratovitski T., van Lare J., Lee M.K., Gonzales V., Jenkins N.A., Copeland N.G., Price D.L., Sisodia S.S. Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 1997, 19:939-945.
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
van Lare, J.3
Lee, M.K.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Price, D.L.8
Sisodia, S.S.9
-
21
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak H., Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. (Berl.) 1991, 82:239-259.
-
(1991)
Acta Neuropathol. (Berl.)
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
22
-
-
77958484985
-
Physical exercise increases Notch activity, proliferation and cell cycle exit of type-3 progenitor cells in adult hippocampal neurogenesis
-
Brandt M.D., Maass A., Kempermann G., Storch A. Physical exercise increases Notch activity, proliferation and cell cycle exit of type-3 progenitor cells in adult hippocampal neurogenesis. Eur. J. Neurosci. 2010, 32:1256-1264.
-
(2010)
Eur. J. Neurosci.
, vol.32
, pp. 1256-1264
-
-
Brandt, M.D.1
Maass, A.2
Kempermann, G.3
Storch, A.4
-
23
-
-
70949107340
-
Inhibition of PI3K-Akt signaling blocks exercise-mediated enhancement of adult neurogenesis and synaptic plasticity in the dentate gyrus
-
Bruel-Jungerman E., Veyrac A., Dufour F., Horwood J., Laroche S., Davis S. Inhibition of PI3K-Akt signaling blocks exercise-mediated enhancement of adult neurogenesis and synaptic plasticity in the dentate gyrus. PLoS One 2009, 4:e7901.
-
(2009)
PLoS One
, vol.4
, pp. e7901
-
-
Bruel-Jungerman, E.1
Veyrac, A.2
Dufour, F.3
Horwood, J.4
Laroche, S.5
Davis, S.6
-
24
-
-
84899511194
-
Temporal features of adult neurogenesis: differences and similarities across mammalian species
-
Brus M., Keller M., Levy F. Temporal features of adult neurogenesis: differences and similarities across mammalian species. Front. Neurosci. 2013, 7:135.
-
(2013)
Front. Neurosci.
, vol.7
, pp. 135
-
-
Brus, M.1
Keller, M.2
Levy, F.3
-
25
-
-
84860726725
-
Total daily physical activity and the risk of AD and cognitive decline in older adults
-
Buchman A.S., Boyle P.A., Yu L., Shah R.C., Wilson R.S., Bennett D.A. Total daily physical activity and the risk of AD and cognitive decline in older adults. Neurology 2012, 78:1323-1329.
-
(2012)
Neurology
, vol.78
, pp. 1323-1329
-
-
Buchman, A.S.1
Boyle, P.A.2
Yu, L.3
Shah, R.C.4
Wilson, R.S.5
Bennett, D.A.6
-
26
-
-
51249090505
-
Glucocorticoid signaling and exercise-induced downregulation of the mineralocorticoid receptor in the induction of adult mouse dentate neurogenesis by treadmill running
-
Chang Y.T., Chen Y.C., Wu C.W., Yu L., Chen H.I., Jen C.J., Kuo Y.M. Glucocorticoid signaling and exercise-induced downregulation of the mineralocorticoid receptor in the induction of adult mouse dentate neurogenesis by treadmill running. Psychoneuroendocrinology 2008, 33:1173-1182.
-
(2008)
Psychoneuroendocrinology
, vol.33
, pp. 1173-1182
-
-
Chang, Y.T.1
Chen, Y.C.2
Wu, C.W.3
Yu, L.4
Chen, H.I.5
Jen, C.J.6
Kuo, Y.M.7
-
27
-
-
0035877756
-
Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695
-
Chishti M.A., Yang D.S., Janus C., Phinney A.L., Horne P., Pearson J., Strome R., Zuker N., Loukides J., French J., Turner S., Lozza G., Grilli M., Kunicki S., Morissette C., Paquette J., Gervais F., Bergeron C., Fraser P.E., Carlson G.A., George-Hyslop P.S., Westaway D. Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J. Biol. Chem. 2001, 276:21562-21570.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21562-21570
-
-
Chishti, M.A.1
Yang, D.S.2
Janus, C.3
Phinney, A.L.4
Horne, P.5
Pearson, J.6
Strome, R.7
Zuker, N.8
Loukides, J.9
French, J.10
Turner, S.11
Lozza, G.12
Grilli, M.13
Kunicki, S.14
Morissette, C.15
Paquette, J.16
Gervais, F.17
Bergeron, C.18
Fraser, P.E.19
Carlson, G.A.20
George-Hyslop, P.S.21
Westaway, D.22
more..
-
28
-
-
10744223642
-
Use of NSE/PS2m-transgenic mice in the study of the protective effect of exercise on Alzheimer's disease
-
Cho J.Y., Hwang D.Y., Kang T.S., Shin D.H., Hwang J.H., Lim C.H., Lee S.H., Lim H.J., Min S.H., Seo S.J., Song Y.S., Nam K.T., Lee K.S., Cho J.S., Kim Y.K. Use of NSE/PS2m-transgenic mice in the study of the protective effect of exercise on Alzheimer's disease. J. Sports Sci. 2003, 21:943-951.
-
(2003)
J. Sports Sci.
, vol.21
, pp. 943-951
-
-
Cho, J.Y.1
Hwang, D.Y.2
Kang, T.S.3
Shin, D.H.4
Hwang, J.H.5
Lim, C.H.6
Lee, S.H.7
Lim, H.J.8
Min, S.H.9
Seo, S.J.10
Song, Y.S.11
Nam, K.T.12
Lee, K.S.13
Cho, J.S.14
Kim, Y.K.15
-
29
-
-
84939572180
-
Treadmill running reverses cognitive declines due to Alzheimer disease
-
Cho J., Shin M.K., Kim D., Lee I., Kim S., Kang H. Treadmill running reverses cognitive declines due to Alzheimer disease. Med. Sci. Sports Exerc. 2015, 47:1814-1824.
-
(2015)
Med. Sci. Sports Exerc.
, vol.47
, pp. 1814-1824
-
-
Cho, J.1
Shin, M.K.2
Kim, D.3
Lee, I.4
Kim, S.5
Kang, H.6
-
30
-
-
84896307597
-
Dopaminergic manipulations and its effects on neurogenesis and motor function in a transgenic mouse model of Huntington's disease
-
Choi M.L., Begeti F., Oh J.H., Lee S.Y., O'Keeffe G.C., Clelland C.D., Tyers P., Cho Z.H., Kim Y.B., Barker R.A. Dopaminergic manipulations and its effects on neurogenesis and motor function in a transgenic mouse model of Huntington's disease. Neurobiol. Dis. 2014, 66:19-27.
-
(2014)
Neurobiol. Dis.
, vol.66
, pp. 19-27
-
-
Choi, M.L.1
Begeti, F.2
Oh, J.H.3
Lee, S.Y.4
O'Keeffe, G.C.5
Clelland, C.D.6
Tyers, P.7
Cho, Z.H.8
Kim, Y.B.9
Barker, R.A.10
-
31
-
-
84905493442
-
Neuritin attenuates cognitive function impairments in tg2576 mouse model of Alzheimer's disease
-
Choi Y., Lee K., Ryu J., Kim H.G., Jeong A.Y., Woo R.S., Lee J.H., Hyun J.W., Hahn S., Kim J.H., Kim H.S. Neuritin attenuates cognitive function impairments in tg2576 mouse model of Alzheimer's disease. PLoS One 2014, 9:e104121.
-
(2014)
PLoS One
, vol.9
, pp. e104121
-
-
Choi, Y.1
Lee, K.2
Ryu, J.3
Kim, H.G.4
Jeong, A.Y.5
Woo, R.S.6
Lee, J.H.7
Hyun, J.W.8
Hahn, S.9
Kim, J.H.10
Kim, H.S.11
-
32
-
-
50249153471
-
Intact neurogenesis is required for benefits of exercise on spatial memory but not motor performance or contextual fear conditioning in C57BL/6J mice
-
Clark P.J., Brzezinska W.J., Thomas M.W., Ryzhenko N.A., Toshkov S.A., Rhodes J.S. Intact neurogenesis is required for benefits of exercise on spatial memory but not motor performance or contextual fear conditioning in C57BL/6J mice. Neuroscience 2008, 155:1048-1058.
-
(2008)
Neuroscience
, vol.155
, pp. 1048-1058
-
-
Clark, P.J.1
Brzezinska, W.J.2
Thomas, M.W.3
Ryzhenko, N.A.4
Toshkov, S.A.5
Rhodes, J.S.6
-
33
-
-
70349467897
-
Functional analysis of neurovascular adaptations to exercise in the dentate gyrus of young adult mice associated with cognitive gain
-
Clark P.J., Brzezinska W.J., Puchalski E.K., Krone D.A., Rhodes J.S. Functional analysis of neurovascular adaptations to exercise in the dentate gyrus of young adult mice associated with cognitive gain. Hippocampus 2009, 19:937-950.
-
(2009)
Hippocampus
, vol.19
, pp. 937-950
-
-
Clark, P.J.1
Brzezinska, W.J.2
Puchalski, E.K.3
Krone, D.A.4
Rhodes, J.S.5
-
34
-
-
84955246060
-
Spatial learning and neurogenesis: effects of cessation of wheel running and survival of novel neurons by engagement in cognitive tasks
-
Clemente Motta-Teixeira L., Takada S.H., Machado-Nils A.V., Nogueira M.I., Xavier G.F. Spatial learning and neurogenesis: effects of cessation of wheel running and survival of novel neurons by engagement in cognitive tasks. Hippocampus 2015, 10.1002/hipo.22560.
-
(2015)
Hippocampus
-
-
Clemente Motta-Teixeira, L.1
Takada, S.H.2
Machado-Nils, A.V.3
Nogueira, M.I.4
Xavier, G.F.5
-
35
-
-
84893929527
-
Acute aerobic exercise increases brain-derived neurotrophic factor levels in elderly with Alzheimer's disease
-
Coelho F.G., Vital T.M., Stein A.M., Arantes F.J., Rueda A.V., Camarini R., Teodorov E., Santos-Galduroz R.F. Acute aerobic exercise increases brain-derived neurotrophic factor levels in elderly with Alzheimer's disease. J. Alzheimers Dis. 2014, 39:401-408.
-
(2014)
J. Alzheimers Dis.
, vol.39
, pp. 401-408
-
-
Coelho, F.G.1
Vital, T.M.2
Stein, A.M.3
Arantes, F.J.4
Rueda, A.V.5
Camarini, R.6
Teodorov, E.7
Santos-Galduroz, R.F.8
-
36
-
-
77956843852
-
Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis
-
Crews L., Adame A., Patrick C., Delaney A., Pham E., Rockenstein E., Hansen L., Masliah E. Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis. J. Neurosci. 2010, 30:12252-12262.
-
(2010)
J. Neurosci.
, vol.30
, pp. 12252-12262
-
-
Crews, L.1
Adame, A.2
Patrick, C.3
Delaney, A.4
Pham, E.5
Rockenstein, E.6
Hansen, L.7
Masliah, E.8
-
37
-
-
84865199264
-
Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study
-
Cribbs D.H., Berchtold N.C., Perreau V., Coleman P.D., Rogers J., Tenner A.J., Cotman C.W. Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study. J. Neuroinflammation 2012, 9:179.
-
(2012)
J. Neuroinflammation
, vol.9
, pp. 179
-
-
Cribbs, D.H.1
Berchtold, N.C.2
Perreau, V.3
Coleman, P.D.4
Rogers, J.5
Tenner, A.J.6
Cotman, C.W.7
-
38
-
-
79960126566
-
Learning increases the survival of newborn neurons provided that learning is difficult to achieve and successful
-
Curlik D.M., Shors T.J. Learning increases the survival of newborn neurons provided that learning is difficult to achieve and successful. J. Cogn. Neurosci. 2011, 23:2159-2170.
-
(2011)
J. Cogn. Neurosci.
, vol.23
, pp. 2159-2170
-
-
Curlik, D.M.1
Shors, T.J.2
-
39
-
-
84929997222
-
Dentate gyrus expression of nestin-immunoreactivity in patients with drug-resistant temporal lobe epilepsy and hippocampal sclerosis
-
D'Alessio L., Konopka H., Escobar E., Acuna A., Oddo S., Solis P., Seoane E., Kochen S. Dentate gyrus expression of nestin-immunoreactivity in patients with drug-resistant temporal lobe epilepsy and hippocampal sclerosis. Seizure 2015, 27:75-79.
-
(2015)
Seizure
, vol.27
, pp. 75-79
-
-
D'Alessio, L.1
Konopka, H.2
Escobar, E.3
Acuna, A.4
Oddo, S.5
Solis, P.6
Seoane, E.7
Kochen, S.8
-
40
-
-
77953505738
-
Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice
-
Demars M., Hu Y.S., Gadadhar A., Lazarov O. Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice. J. Neurosci. Res. 2010, 88:2103-2117.
-
(2010)
J. Neurosci. Res.
, vol.88
, pp. 2103-2117
-
-
Demars, M.1
Hu, Y.S.2
Gadadhar, A.3
Lazarov, O.4
-
41
-
-
84908118526
-
Inflammation early in life is a vulnerability factor for emotional behavior at adolescence and for lipopolysaccharide-induced spatial memory and neurogenesis alteration at adulthood
-
Dinel A.L., Joffre C., Trifilieff P., Aubert A., Foury A., Le Ruyet P., Laye S. Inflammation early in life is a vulnerability factor for emotional behavior at adolescence and for lipopolysaccharide-induced spatial memory and neurogenesis alteration at adulthood. J. Neuroinflammation 2014, 11:155.
-
(2014)
J. Neuroinflammation
, vol.11
, pp. 155
-
-
Dinel, A.L.1
Joffre, C.2
Trifilieff, P.3
Aubert, A.4
Foury, A.5
Le Ruyet, P.6
Laye, S.7
-
42
-
-
84958234083
-
Dietary approaches and supplements in the prevention of cognitive decline and Alzheimer's disease
-
Dominguez L.J., Barbagallo M. Dietary approaches and supplements in the prevention of cognitive decline and Alzheimer's disease. Curr. Pharm. Des. 2016, 22:688-700.
-
(2016)
Curr. Pharm. Des.
, vol.22
, pp. 688-700
-
-
Dominguez, L.J.1
Barbagallo, M.2
-
43
-
-
32544460592
-
Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease
-
Donovan M.H., Yazdani U., Norris R.D., Games D., German D.C., Eisch A.J. Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease. J. Comp. Neurol. 2006, 495:70-83.
-
(2006)
J. Comp. Neurol.
, vol.495
, pp. 70-83
-
-
Donovan, M.H.1
Yazdani, U.2
Norris, R.D.3
Games, D.4
German, D.C.5
Eisch, A.J.6
-
44
-
-
45849151100
-
Spatial relational memory requires hippocampal adult neurogenesis
-
Dupret D., Revest J.M., Koehl M., Ichas F., De Giorgi F., Costet P., Abrous D.N., Piazza P.V. Spatial relational memory requires hippocampal adult neurogenesis. PLoS One 2008, 3:e1959.
-
(2008)
PLoS One
, vol.3
, pp. e1959
-
-
Dupret, D.1
Revest, J.M.2
Koehl, M.3
Ichas, F.4
De Giorgi, F.5
Costet, P.6
Abrous, D.N.7
Piazza, P.V.8
-
45
-
-
0344742225
-
Inflammation is detrimental for neurogenesis in adult brain
-
Ekdahl C.T., Claasen J.-H., Bonde S., Kokaia Z., Lindvall O. Inflammation is detrimental for neurogenesis in adult brain. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:13632-13637.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 13632-13637
-
-
Ekdahl, C.T.1
Claasen, J.-H.2
Bonde, S.3
Kokaia, Z.4
Lindvall, O.5
-
46
-
-
44849096458
-
Neurogenesis and alterations of neural stem cells in mouse models of cerebral amyloidosis
-
Ermini F.V., Grathwohl S., Radde R., Yamaguchi M., Staufenbiel M., Palmer T.D., Jucker M. Neurogenesis and alterations of neural stem cells in mouse models of cerebral amyloidosis. Am. J. Pathol. 2008, 172:1520-1528.
-
(2008)
Am. J. Pathol.
, vol.172
, pp. 1520-1528
-
-
Ermini, F.V.1
Grathwohl, S.2
Radde, R.3
Yamaguchi, M.4
Staufenbiel, M.5
Palmer, T.D.6
Jucker, M.7
-
47
-
-
54949150630
-
The timing of differentiation of adult hippocampal neurons is crucial for spatial memory
-
Farioli-Vecchioli S., Saraulli D., Costanzi M., Pacioni S., Cina I., Aceti M., Micheli L., Bacci A., Cestari V., Tirone F. The timing of differentiation of adult hippocampal neurons is crucial for spatial memory. PLoS Biol. 2008, 6:e246.
-
(2008)
PLoS Biol.
, vol.6
, pp. e246
-
-
Farioli-Vecchioli, S.1
Saraulli, D.2
Costanzi, M.3
Pacioni, S.4
Cina, I.5
Aceti, M.6
Micheli, L.7
Bacci, A.8
Cestari, V.9
Tirone, F.10
-
48
-
-
81155137748
-
Short-term, moderate exercise is capable of inducing structural, BDNF-independent hippocampal plasticity
-
Ferreira A.F., Real C.C., Rodrigues A.C., Alves A.S., Britto L.R. Short-term, moderate exercise is capable of inducing structural, BDNF-independent hippocampal plasticity. Brain Res. 2011, 1425:111-122.
-
(2011)
Brain Res.
, vol.1425
, pp. 111-122
-
-
Ferreira, A.F.1
Real, C.C.2
Rodrigues, A.C.3
Alves, A.S.4
Britto, L.R.5
-
49
-
-
33947529793
-
Interleukin-6 in acute exercise and training: what is the biological relevance?
-
Fischer C.P. Interleukin-6 in acute exercise and training: what is the biological relevance?. Exerc. Immunol. Rev. 2006, 12:6-33.
-
(2006)
Exerc. Immunol. Rev.
, vol.12
, pp. 6-33
-
-
Fischer, C.P.1
-
50
-
-
70249097351
-
Function of tau protein in adult newborn neurons
-
Fuster-Matanzo A., de Barreda E.G., Dawson H.N., Vitek M.P., Avila J., Hernandez F. Function of tau protein in adult newborn neurons. FEBS Lett. 2009, 583:3063-3068.
-
(2009)
FEBS Lett.
, vol.583
, pp. 3063-3068
-
-
Fuster-Matanzo, A.1
de Barreda, E.G.2
Dawson, H.N.3
Vitek, M.P.4
Avila, J.5
Hernandez, F.6
-
51
-
-
84865160532
-
Tau protein and adult hippocampal neurogenesis
-
Fuster-Matanzo A., Llorens-Martin M., Jurado-Arjona J., Avila J., Hernandez F. Tau protein and adult hippocampal neurogenesis. Front. Neurosci. 2012, 6:104.
-
(2012)
Front. Neurosci.
, vol.6
, pp. 104
-
-
Fuster-Matanzo, A.1
Llorens-Martin, M.2
Jurado-Arjona, J.3
Avila, J.4
Hernandez, F.5
-
52
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
-
Games D., Adams D., Alessandrini R., Barbour R., Berthelette P., Blackwell C., Carr T., Clemens J., Donaldson T., Gillespie F., et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature 1995, 373:523-527.
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
-
53
-
-
84859485513
-
Melatonin plus physical exercise are highly neuroprotective in the 3xTg-AD mouse
-
Garcia-Mesa Y., Gimenez-Llort L., Lopez L.C., Venegas C., Cristofol R., Escames G., Acuna-Castroviejo D., Sanfeliu C. Melatonin plus physical exercise are highly neuroprotective in the 3xTg-AD mouse. Neurobiol. Aging 2012, 33(1124):e1113-1129.
-
(2012)
Neurobiol. Aging
, vol.33
, Issue.1124
, pp. e1113-1129
-
-
Garcia-Mesa, Y.1
Gimenez-Llort, L.2
Lopez, L.C.3
Venegas, C.4
Cristofol, R.5
Escames, G.6
Acuna-Castroviejo, D.7
Sanfeliu, C.8
-
54
-
-
84861923951
-
Voluntary wheel running in mice increases the rate of neurogenesis without affecting anxiety-related behaviour in single tests
-
Garrett L., Lie D.C., Hrabe de Angelis M., Wurst W., Holter S.M. Voluntary wheel running in mice increases the rate of neurogenesis without affecting anxiety-related behaviour in single tests. BMC Neurosci. 2012, 13:61.
-
(2012)
BMC Neurosci.
, vol.13
, pp. 61
-
-
Garrett, L.1
Lie, D.C.2
Hrabe de Angelis, M.3
Wurst, W.4
Holter, S.M.5
-
55
-
-
84874882726
-
Sustained interleukin-1beta overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model
-
Ghosh S., Wu M.D., Shaftel S.S., Kyrkanides S., LaFerla F.M., Olschowka J.A., O'Banion M.K. Sustained interleukin-1beta overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model. J. Neurosci. 2013, 33:5053-5064.
-
(2013)
J. Neurosci.
, vol.33
, pp. 5053-5064
-
-
Ghosh, S.1
Wu, M.D.2
Shaftel, S.S.3
Kyrkanides, S.4
LaFerla, F.M.5
Olschowka, J.A.6
O'Banion, M.K.7
-
56
-
-
84904350824
-
Voluntary wheel running, but not a diet containing (-)-epigallocatechin-3-gallate and beta-alanine, improves learning, memory and hippocampal neurogenesis in aged mice
-
Gibbons T.E., Pence B.D., Petr G., Ossyra J.M., Mach H.C., Bhattacharya T.K., Perez S., Martin S.A., McCusker R.H., Kelley K.W., Rhodes J.S., Johnson R.W., Woods J.A. Voluntary wheel running, but not a diet containing (-)-epigallocatechin-3-gallate and beta-alanine, improves learning, memory and hippocampal neurogenesis in aged mice. Behav. Brain Res. 2014, 272:131-140.
-
(2014)
Behav. Brain Res.
, vol.272
, pp. 131-140
-
-
Gibbons, T.E.1
Pence, B.D.2
Petr, G.3
Ossyra, J.M.4
Mach, H.C.5
Bhattacharya, T.K.6
Perez, S.7
Martin, S.A.8
McCusker, R.H.9
Kelley, K.W.10
Rhodes, J.S.11
Johnson, R.W.12
Woods, J.A.13
-
57
-
-
77953058601
-
Blockade of insulin-like growth factor-I has complex effects on structural plasticity in the hippocampus
-
Glasper E.R., Llorens-Martin M.V., Leuner B., Gould E., Trejo J.L. Blockade of insulin-like growth factor-I has complex effects on structural plasticity in the hippocampus. Hippocampus 2010, 20:706-712.
-
(2010)
Hippocampus
, vol.20
, pp. 706-712
-
-
Glasper, E.R.1
Llorens-Martin, M.V.2
Leuner, B.3
Gould, E.4
Trejo, J.L.5
-
58
-
-
80052078622
-
The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease
-
Gleeson M., Bishop N.C., Stensel D.J., Lindley M.R., Mastana S.S., Nimmo M.A. The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease. Nat. Rev. Immunol. 2011, 11:607-615.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 607-615
-
-
Gleeson, M.1
Bishop, N.C.2
Stensel, D.J.3
Lindley, M.R.4
Mastana, S.S.5
Nimmo, M.A.6
-
59
-
-
84978072759
-
Comparing three methods of computerised cognitive training for older adults with subclinical cognitive decline
-
Gooding A.L., Choi J., Fiszdon J.M., Wilkins K., Kirwin P.D., van Dyck C.H., Devanand D., Bell M.D., Rivera Mindt M. Comparing three methods of computerised cognitive training for older adults with subclinical cognitive decline. Neuropsychol. Rehabil. 2015, 1-12.
-
(2015)
Neuropsychol. Rehabil.
, pp. 1-12
-
-
Gooding, A.L.1
Choi, J.2
Fiszdon, J.M.3
Wilkins, K.4
Kirwin, P.D.5
van Dyck, C.H.6
Devanand, D.7
Bell, M.D.8
Rivera Mindt, M.9
-
60
-
-
78349309044
-
Young hippocampal neurons are critical for recent and remote spatial memory in adult mice
-
Goodman T., Trouche S., Massou I., Verret L., Zerwas M., Roullet P., Rampon C. Young hippocampal neurons are critical for recent and remote spatial memory in adult mice. Neuroscience 2010, 171:769-778.
-
(2010)
Neuroscience
, vol.171
, pp. 769-778
-
-
Goodman, T.1
Trouche, S.2
Massou, I.3
Verret, L.4
Zerwas, M.5
Roullet, P.6
Rampon, C.7
-
61
-
-
70349452132
-
Exercise enhances hippocampal-dependent learning in the rat: evidence for a BDNF-related mechanism
-
Griffin E.W., Bechara R.G., Birch A.M., Kelly A.M. Exercise enhances hippocampal-dependent learning in the rat: evidence for a BDNF-related mechanism. Hippocampus 2009, 19:973-980.
-
(2009)
Hippocampus
, vol.19
, pp. 973-980
-
-
Griffin, E.W.1
Bechara, R.G.2
Birch, A.M.3
Kelly, A.M.4
-
62
-
-
77956826478
-
Widespread deficits in adult neurogenesis precede plaque and tangle formation in the 3xTg mouse model of Alzheimer's disease
-
Hamilton L.K., Aumont A., Julien C., Vadnais A., Calon F., Fernandes K.J. Widespread deficits in adult neurogenesis precede plaque and tangle formation in the 3xTg mouse model of Alzheimer's disease. Eur. J. Neurosci. 2010, 32:905-920.
-
(2010)
Eur. J. Neurosci.
, vol.32
, pp. 905-920
-
-
Hamilton, L.K.1
Aumont, A.2
Julien, C.3
Vadnais, A.4
Calon, F.5
Fernandes, K.J.6
-
63
-
-
84908214258
-
Cognitively-based methods of enhancing and maintaining functioning in those at risk of Alzheimer's disease
-
Hampstead B.M., Mosti C.B., Swirsky-Sacchetti T. Cognitively-based methods of enhancing and maintaining functioning in those at risk of Alzheimer's disease. J. Alzheimers Dis. 2014, 42(Suppl. 4):S483-493.
-
(2014)
J. Alzheimers Dis.
, vol.42
, pp. S483-493
-
-
Hampstead, B.M.1
Mosti, C.B.2
Swirsky-Sacchetti, T.3
-
64
-
-
72649097241
-
Sustained hippocampal IL-1beta overexpression impairs contextual and spatial memory in transgenic mice
-
Hein A.M., Stasko M.R., Matousek S.B., Scott-McKean J.J., Maier S.F., Olschowka J.A., Costa A.C., O'Banion M.K. Sustained hippocampal IL-1beta overexpression impairs contextual and spatial memory in transgenic mice. Brain Behav. Immun. 2010, 24:243-253.
-
(2010)
Brain Behav. Immun.
, vol.24
, pp. 243-253
-
-
Hein, A.M.1
Stasko, M.R.2
Matousek, S.B.3
Scott-McKean, J.J.4
Maier, S.F.5
Olschowka, J.A.6
Costa, A.C.7
O'Banion, M.K.8
-
65
-
-
1242316182
-
Prominent decline of newborn cell proliferation, differentiation, and apoptosis in the aging dentate gyrus, in absence of an age-related hypothalamus-pituitary-adrenal axis activation
-
Heine V.M., Maslam S., Joels M., Lucassen P.J. Prominent decline of newborn cell proliferation, differentiation, and apoptosis in the aging dentate gyrus, in absence of an age-related hypothalamus-pituitary-adrenal axis activation. Neurobiol. Aging 2004, 25:361-375.
-
(2004)
Neurobiol. Aging
, vol.25
, pp. 361-375
-
-
Heine, V.M.1
Maslam, S.2
Joels, M.3
Lucassen, P.J.4
-
66
-
-
84926370173
-
Neuroinflammation in Alzheimer's disease
-
Heneka M.T., Carson M.J., El Khoury J., Landreth G.E., Brosseron F., Feinstein D.L., Jacobs A.H., Wyss-Coray T., Vitorica J., Ransohoff R.M., Herrup K., Frautschy S.A., Finsen B., Brown G.C., Verkhratsky A., Yamanaka K., Koistinaho J., Latz E., Halle A., Petzold G.C., Town T., Morgan D., Shinohara M.L., Perry V.H., Holmes C., Bazan N.G., Brooks D.J., Hunot S., Joseph B., Deigendesch N., Garaschuk O., Boddeke E., Dinarello C.A., Breitner J.C., Cole G.M., Golenbock D.T., Kummer M.P. Neuroinflammation in Alzheimer's disease. Lancet Neurol. 2015, 14:388-405.
-
(2015)
Lancet Neurol.
, vol.14
, pp. 388-405
-
-
Heneka, M.T.1
Carson, M.J.2
El Khoury, J.3
Landreth, G.E.4
Brosseron, F.5
Feinstein, D.L.6
Jacobs, A.H.7
Wyss-Coray, T.8
Vitorica, J.9
Ransohoff, R.M.10
Herrup, K.11
Frautschy, S.A.12
Finsen, B.13
Brown, G.C.14
Verkhratsky, A.15
Yamanaka, K.16
Koistinaho, J.17
Latz, E.18
Halle, A.19
Petzold, G.C.20
Town, T.21
Morgan, D.22
Shinohara, M.L.23
Perry, V.H.24
Holmes, C.25
Bazan, N.G.26
Brooks, D.J.27
Hunot, S.28
Joseph, B.29
Deigendesch, N.30
Garaschuk, O.31
Boddeke, E.32
Dinarello, C.A.33
Breitner, J.C.34
Cole, G.M.35
Golenbock, D.T.36
Kummer, M.P.37
more..
-
67
-
-
84929921146
-
Immune attack: the role of inflammation in Alzheimer disease
-
Heppner F.L., Ransohoff R.M., Becher B. Immune attack: the role of inflammation in Alzheimer disease. Nat. Rev. Neurosci. 2015, 16:358-372.
-
(2015)
Nat. Rev. Neurosci.
, vol.16
, pp. 358-372
-
-
Heppner, F.L.1
Ransohoff, R.M.2
Becher, B.3
-
68
-
-
51149120624
-
Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice
-
Hickman S.E., Allison E.K., El Khoury J. Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice. J. Neurosci. 2008, 28:8354-8360.
-
(2008)
J. Neurosci.
, vol.28
, pp. 8354-8360
-
-
Hickman, S.E.1
Allison, E.K.2
El Khoury, J.3
-
69
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
Holcomb L., Gordon M.N., McGowan E., Yu X., Benkovic S., Jantzen P., Wright K., Saad I., Mueller R., Morgan D., Sanders S., Zehr C., O'Campo K., Hardy J., Prada C.M., Eckman C., Younkin S., Hsiao K., Duff K. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nat. Med. 1998, 4:97-100.
-
(1998)
Nat. Med.
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
Wright, K.7
Saad, I.8
Mueller, R.9
Morgan, D.10
Sanders, S.11
Zehr, C.12
O'Campo, K.13
Hardy, J.14
Prada, C.M.15
Eckman, C.16
Younkin, S.17
Hsiao, K.18
Duff, K.19
-
70
-
-
77951812710
-
Essential role of tau phosphorylation in adult hippocampal neurogenesis
-
Hong X.P., Peng C.X., Wei W., Tian Q., Liu Y.H., Yao X.Q., Zhang Y., Cao F.Y., Wang Q., Wang J.Z. Essential role of tau phosphorylation in adult hippocampal neurogenesis. Hippocampus 2010, 20:1339-1349.
-
(2010)
Hippocampus
, vol.20
, pp. 1339-1349
-
-
Hong, X.P.1
Peng, C.X.2
Wei, W.3
Tian, Q.4
Liu, Y.H.5
Yao, X.Q.6
Zhang, Y.7
Cao, F.Y.8
Wang, Q.9
Wang, J.Z.10
-
71
-
-
13044287361
-
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
-
Hsia A.Y., Masliah E., McConlogue L., Yu G.Q., Tatsuno G., Hu K., Kholodenko D., Malenka R.C., Nicoll R.A., Mucke L. Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:3228-3233.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 3228-3233
-
-
Hsia, A.Y.1
Masliah, E.2
McConlogue, L.3
Yu, G.Q.4
Tatsuno, G.5
Hu, K.6
Kholodenko, D.7
Malenka, R.C.8
Nicoll, R.A.9
Mucke, L.10
-
72
-
-
0029742199
-
Correlative memory deficits, abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., Cole G. Correlative memory deficits, abeta elevation, and amyloid plaques in transgenic mice. Science 1996, 274:99-102.
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
73
-
-
84962420842
-
-
org/2015
-
http://www.worldalzreport2015, org/2015.
-
-
-
-
74
-
-
0036275638
-
Alterations in behavior amyloid beta-42, caspase-3, and Cox-2 in mutant PS2 transgenic mouse model of Alzheimer's disease
-
Hwang D.Y., Chae K.R., Kang T.S., Hwang J.H., Lim C.H., Kang H.K., Goo J.S., Lee M.R., Lim H.J., Min S.H., Cho J.Y., Hong J.T., Song C.W., Paik S.G., Cho J.S., Kim Y.K. Alterations in behavior amyloid beta-42, caspase-3, and Cox-2 in mutant PS2 transgenic mouse model of Alzheimer's disease. FASEB J. 2002, 16:805-813.
-
(2002)
FASEB J.
, vol.16
, pp. 805-813
-
-
Hwang, D.Y.1
Chae, K.R.2
Kang, T.S.3
Hwang, J.H.4
Lim, C.H.5
Kang, H.K.6
Goo, J.S.7
Lee, M.R.8
Lim, H.J.9
Min, S.H.10
Cho, J.Y.11
Hong, J.T.12
Song, C.W.13
Paik, S.G.14
Cho, J.S.15
Kim, Y.K.16
-
75
-
-
84893645323
-
Impairments in neurogenesis are not tightly linked to depressive behavior in a transgenic mouse model of Alzheimer's disease
-
Iascone D.M., Padidam S., Pyfer M.S., Zhang X., Zhao L., Chin J. Impairments in neurogenesis are not tightly linked to depressive behavior in a transgenic mouse model of Alzheimer's disease. PLoS One 2013, 8:e79651.
-
(2013)
PLoS One
, vol.8
, pp. e79651
-
-
Iascone, D.M.1
Padidam, S.2
Pyfer, M.S.3
Zhang, X.4
Zhao, L.5
Chin, J.6
-
76
-
-
77954512014
-
CHF5074, a novel gamma-secretase modulator, restores hippocampal neurogenesis potential and reverses contextual memory deficit in a transgenic mouse model of Alzheimer's disease
-
Imbimbo B.P., Giardino L., Sivilia S., Giuliani A., Gusciglio M., Pietrini V., Del Giudice E., D'Arrigo A., Leon A., Villetti G., Calza L. CHF5074, a novel gamma-secretase modulator, restores hippocampal neurogenesis potential and reverses contextual memory deficit in a transgenic mouse model of Alzheimer's disease. J. Alzheimers Dis. 2010, 20:159-173.
-
(2010)
J. Alzheimers Dis.
, vol.20
, pp. 159-173
-
-
Imbimbo, B.P.1
Giardino, L.2
Sivilia, S.3
Giuliani, A.4
Gusciglio, M.5
Pietrini, V.6
Del Giudice, E.7
D'Arrigo, A.8
Leon, A.9
Villetti, G.10
Calza, L.11
-
77
-
-
84925866263
-
Long-term mild exercise training enhances hippocampus-dependent memory in rats
-
Inoue K., Hanaoka Y., Nishijima T., Okamoto M., Chang H., Saito T., Soya H. Long-term mild exercise training enhances hippocampus-dependent memory in rats. Int. J. Sports Med. 2015, 36:280-285.
-
(2015)
Int. J. Sports Med.
, vol.36
, pp. 280-285
-
-
Inoue, K.1
Hanaoka, Y.2
Nishijima, T.3
Okamoto, M.4
Chang, H.5
Saito, T.6
Soya, H.7
-
78
-
-
84936863942
-
Long-term mild, rather than intense, exercise enhances adult hippocampal neurogenesis and greatly changes the transcriptomic profile of the hippocampus
-
Inoue K., Okamoto M., Shibato J., Lee M.C., Matsui T., Rakwal R., Soya H. Long-term mild, rather than intense, exercise enhances adult hippocampal neurogenesis and greatly changes the transcriptomic profile of the hippocampus. PLoS One 2015, 10:e0128720.
-
(2015)
PLoS One
, vol.10
, pp. e0128720
-
-
Inoue, K.1
Okamoto, M.2
Shibato, J.3
Lee, M.C.4
Matsui, T.5
Rakwal, R.6
Soya, H.7
-
79
-
-
0344305380
-
Environmental enrichment exacerbates amyloid plaque formation in a transgenic mouse model of Alzheimer disease
-
Jankowsky J.L., Xu G., Fromholt D., Gonzales V., Borchelt D.R. Environmental enrichment exacerbates amyloid plaque formation in a transgenic mouse model of Alzheimer disease. J. Neuropathol. Exp. Neurol. 2003, 62:1220-1227.
-
(2003)
J. Neuropathol. Exp. Neurol.
, vol.62
, pp. 1220-1227
-
-
Jankowsky, J.L.1
Xu, G.2
Fromholt, D.3
Gonzales, V.4
Borchelt, D.R.5
-
80
-
-
4444269849
-
Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice
-
Jin K., Galvan V., Xie L., Mao X.O., Gorostiza O.F., Bredesen D.E., Greenberg D.A. Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:13363-13367.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 13363-13367
-
-
Jin, K.1
Galvan, V.2
Xie, L.3
Mao, X.O.4
Gorostiza, O.F.5
Bredesen, D.E.6
Greenberg, D.A.7
-
81
-
-
0346458659
-
Increased hippocampal neurogenesis in Alzheimer's disease
-
Jin K., Peel A.L., Mao X.O., Xie L., Cottrell B.A., Henshall D.C., Greenberg D.A. Increased hippocampal neurogenesis in Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:343-347.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 343-347
-
-
Jin, K.1
Peel, A.L.2
Mao, X.O.3
Xie, L.4
Cottrell, B.A.5
Henshall, D.C.6
Greenberg, D.A.7
-
82
-
-
84920405563
-
Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models
-
Johansson J.U., Woodling N.S., Wang Q., Panchal M., Liang X., Trueba-Saiz A., Brown H.D., Mhatre S.D., Loui T., Andreasson K.I. Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models. J. Clin. Invest. 2015, 125:350-364.
-
(2015)
J. Clin. Invest.
, vol.125
, pp. 350-364
-
-
Johansson, J.U.1
Woodling, N.S.2
Wang, Q.3
Panchal, M.4
Liang, X.5
Trueba-Saiz, A.6
Brown, H.D.7
Mhatre, S.D.8
Loui, T.9
Andreasson, K.I.10
-
83
-
-
84938630567
-
Reducing Abeta load and tau phosphorylation: emerging perspective for treating Alzheimer's disease
-
Kalra J., Khan A. Reducing Abeta load and tau phosphorylation: emerging perspective for treating Alzheimer's disease. Eur. J. Pharmacol. 2015, 764:571-581.
-
(2015)
Eur. J. Pharmacol.
, vol.764
, pp. 571-581
-
-
Kalra, J.1
Khan, A.2
-
84
-
-
84937598818
-
FGF signaling is necessary for neurogenesis in young mice and sufficient to reverse its decline in old mice
-
Kang W., Hebert J.M. FGF signaling is necessary for neurogenesis in young mice and sufficient to reverse its decline in old mice. J. Neurosci. 2015, 35:10217-10223.
-
(2015)
J. Neurosci.
, vol.35
, pp. 10217-10223
-
-
Kang, W.1
Hebert, J.M.2
-
85
-
-
79960200124
-
Selective improvement of cognitive function in adult and aged APP/PS1 transgenic mice by continuous non-shock treadmill exercise
-
Ke H.C., Huang H.J., Liang K.C., Hsieh-Li H.M. Selective improvement of cognitive function in adult and aged APP/PS1 transgenic mice by continuous non-shock treadmill exercise. Brain Res. 2011, 1403:1-11.
-
(2011)
Brain Res.
, vol.1403
, pp. 1-11
-
-
Ke, H.C.1
Huang, H.J.2
Liang, K.C.3
Hsieh-Li, H.M.4
-
86
-
-
84929346606
-
Non-pharmacological approaches to cognitive enhancement
-
Kelly A.M. Non-pharmacological approaches to cognitive enhancement. Handb. Exp. Pharmacol. 2015, 228:417-439.
-
(2015)
Handb. Exp. Pharmacol.
, vol.228
, pp. 417-439
-
-
Kelly, A.M.1
-
87
-
-
76149113942
-
Effects of a physical training programme on cognitive function and walking efficiency in elderly persons with dementia
-
Kemoun G., Thibaud M., Roumagne N., Carette P., Albinet C., Toussaint L., Paccalin M., Dugue B. Effects of a physical training programme on cognitive function and walking efficiency in elderly persons with dementia. Dement. Geriatr. Cogn. Disord. 2010, 29:109-114.
-
(2010)
Dement. Geriatr. Cogn. Disord.
, vol.29
, pp. 109-114
-
-
Kemoun, G.1
Thibaud, M.2
Roumagne, N.3
Carette, P.4
Albinet, C.5
Toussaint, L.6
Paccalin, M.7
Dugue, B.8
-
88
-
-
0030937293
-
More hippocampal neurons in adult mice living in an enriched environment
-
Kempermann G., Kuhn H.G., Gage F.H. More hippocampal neurons in adult mice living in an enriched environment. Nature 1997, 386:493-495.
-
(1997)
Nature
, vol.386
, pp. 493-495
-
-
Kempermann, G.1
Kuhn, H.G.2
Gage, F.H.3
-
89
-
-
77955814637
-
CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer's disease-like pathogenesis in APP + PS1 bigenic mice
-
Kiyota T., Okuyama S., Swan R.J., Jacobsen M.T., Gendelman H.E., Ikezu T. CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer's disease-like pathogenesis in APP + PS1 bigenic mice. FASEB J. 2010, 24:3093-3102.
-
(2010)
FASEB J.
, vol.24
, pp. 3093-3102
-
-
Kiyota, T.1
Okuyama, S.2
Swan, R.J.3
Jacobsen, M.T.4
Gendelman, H.E.5
Ikezu, T.6
-
90
-
-
84855166859
-
Running is the neurogenic and neurotrophic stimulus in environmental enrichment
-
Kobilo T., Liu Q.R., Gandhi K., Mughal M., Shaham Y., van Praag H. Running is the neurogenic and neurotrophic stimulus in environmental enrichment. Learn. Mem. 2011, 18:605-609.
-
(2011)
Learn. Mem.
, vol.18
, pp. 605-609
-
-
Kobilo, T.1
Liu, Q.R.2
Gandhi, K.3
Mughal, M.4
Shaham, Y.5
van Praag, H.6
-
91
-
-
84870740056
-
Neurogenesis, inflammation and behavior
-
Kohman R.A., Rhodes J.S. Neurogenesis, inflammation and behavior. Brain Behav. Immun. 2013, 27:22-32.
-
(2013)
Brain Behav. Immun.
, vol.27
, pp. 22-32
-
-
Kohman, R.A.1
Rhodes, J.S.2
-
92
-
-
84929281851
-
Human tau expression reduces adult neurogenesis in a mouse model of tauopathy
-
Komuro Y., Xu G., Bhaskar K., Lamb B.T. Human tau expression reduces adult neurogenesis in a mouse model of tauopathy. Neurobiol. Aging 2015, 36:2034-2042.
-
(2015)
Neurobiol. Aging
, vol.36
, pp. 2034-2042
-
-
Komuro, Y.1
Xu, G.2
Bhaskar, K.3
Lamb, B.T.4
-
93
-
-
38649092266
-
IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress
-
Koo J.W., Duman R.S. IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:751-756.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 751-756
-
-
Koo, J.W.1
Duman, R.S.2
-
94
-
-
84939811954
-
Neuroprotective effects of treadmill exercise on BDNF and PI3-K/Akt signaling pathway in the cortex of transgenic mice model of Alzheimer's disease
-
Koo J.H., Kwon I.S., Kang E.B., Lee C.K., Lee N.H., Kwon M.G., Cho I.H., Cho J.Y. Neuroprotective effects of treadmill exercise on BDNF and PI3-K/Akt signaling pathway in the cortex of transgenic mice model of Alzheimer's disease. J. Exerc. Nutr. Biochem. 2013, 17:151-160.
-
(2013)
J. Exerc. Nutr. Biochem.
, vol.17
, pp. 151-160
-
-
Koo, J.H.1
Kwon, I.S.2
Kang, E.B.3
Lee, C.K.4
Lee, N.H.5
Kwon, M.G.6
Cho, I.H.7
Cho, J.Y.8
-
95
-
-
84884676997
-
Modifications of hippocampal circuits and early disruption of adult neurogenesis in the tg2576 mouse model of Alzheimer's disease
-
Krezymon A., Richetin K., Halley H., Roybon L., Lassalle J.M., Frances B., Verret L., Rampon C. Modifications of hippocampal circuits and early disruption of adult neurogenesis in the tg2576 mouse model of Alzheimer's disease. PLoS One 2013, 8:e76497.
-
(2013)
PLoS One
, vol.8
, pp. e76497
-
-
Krezymon, A.1
Richetin, K.2
Halley, H.3
Roybon, L.4
Lassalle, J.M.5
Frances, B.6
Verret, L.7
Rampon, C.8
-
96
-
-
33748188974
-
Physical exercise prevents age-related decline in precursor cell activity in the mouse dentate gyrus
-
Kronenberg G., Bick-Sander A., Bunk E., Wolf C., Ehninger D., Kempermann G. Physical exercise prevents age-related decline in precursor cell activity in the mouse dentate gyrus. Neurobiol. Aging 2006, 27:1505-1513.
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 1505-1513
-
-
Kronenberg, G.1
Bick-Sander, A.2
Bunk, E.3
Wolf, C.4
Ehninger, D.5
Kempermann, G.6
-
97
-
-
84862693569
-
Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice
-
Krstic D., Madhusudan A., Doehner J., Vogel P., Notter T., Imhof C., Manalastas A., Hilfiker M., Pfister S., Schwerdel C., Riether C., Meyer U., Knuesel I. Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice. J. Neuroinflammation 2012, 9:151.
-
(2012)
J. Neuroinflammation
, vol.9
, pp. 151
-
-
Krstic, D.1
Madhusudan, A.2
Doehner, J.3
Vogel, P.4
Notter, T.5
Imhof, C.6
Manalastas, A.7
Hilfiker, M.8
Pfister, S.9
Schwerdel, C.10
Riether, C.11
Meyer, U.12
Knuesel, I.13
-
98
-
-
0029863342
-
Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation
-
Kuhn H.G., Dickinson-Anson H., Gage F.H. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J. Neurosci. 1996, 16:2027-2033.
-
(1996)
J. Neurosci.
, vol.16
, pp. 2027-2033
-
-
Kuhn, H.G.1
Dickinson-Anson, H.2
Gage, F.H.3
-
99
-
-
33644800309
-
Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older
-
Larson E.B., Wang L., Bowen J.D., McCormick W.C., Teri L., Crane P., Kukull W. Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older. Ann. Intern. Med. 2006, 144:73-81.
-
(2006)
Ann. Intern. Med.
, vol.144
, pp. 73-81
-
-
Larson, E.B.1
Wang, L.2
Bowen, J.D.3
McCormick, W.C.4
Teri, L.5
Crane, P.6
Kukull, W.7
-
100
-
-
84916600279
-
Non-pharmacological strategies to delay cognitive decline
-
Lautenschlager N.T., Anstey K.J., Kurz A.F. Non-pharmacological strategies to delay cognitive decline. Maturitas 2014, 79:170-173.
-
(2014)
Maturitas
, vol.79
, pp. 170-173
-
-
Lautenschlager, N.T.1
Anstey, K.J.2
Kurz, A.F.3
-
101
-
-
20044377403
-
Environmental enrichment reduces abeta levels and amyloid deposition in transgenic mice
-
Lazarov O., Robinson J., Tang Y.P., Hairston I.S., Korade-Mirnics Z., Lee V.M., Hersh L.B., Sapolsky R.M., Mirnics K., Sisodia S.S. Environmental enrichment reduces abeta levels and amyloid deposition in transgenic mice. Cell 2005, 120:701-713.
-
(2005)
Cell
, vol.120
, pp. 701-713
-
-
Lazarov, O.1
Robinson, J.2
Tang, Y.P.3
Hairston, I.S.4
Korade-Mirnics, Z.5
Lee, V.M.6
Hersh, L.B.7
Sapolsky, R.M.8
Mirnics, K.9
Sisodia, S.S.10
-
102
-
-
84938057068
-
Icariin decreases both APP and Abeta levels and increases neurogenesis in the brain of Tg2576 mice
-
Li F., Dong H.X., Gong Q.H., Wu Q., Jin F., Shi J.S. Icariin decreases both APP and Abeta levels and increases neurogenesis in the brain of Tg2576 mice. Neuroscience 2015, 304:29-35.
-
(2015)
Neuroscience
, vol.304
, pp. 29-35
-
-
Li, F.1
Dong, H.X.2
Gong, Q.H.3
Wu, Q.4
Jin, F.5
Shi, J.S.6
-
103
-
-
84921297509
-
Running exercise delays neurodegeneration in amygdala and hippocampus of Alzheimer's disease (APP/PS1) transgenic mice
-
Lin T.W., Shih Y.H., Chen S.J., Lien C.H., Chang C.Y., Huang T.Y., Chen S.H., Jen C.J., Kuo Y.M. Running exercise delays neurodegeneration in amygdala and hippocampus of Alzheimer's disease (APP/PS1) transgenic mice. Neurobiol. Learn. Mem. 2015, 118:189-197.
-
(2015)
Neurobiol. Learn. Mem.
, vol.118
, pp. 189-197
-
-
Lin, T.W.1
Shih, Y.H.2
Chen, S.J.3
Lien, C.H.4
Chang, C.Y.5
Huang, T.Y.6
Chen, S.H.7
Jen, C.J.8
Kuo, Y.M.9
-
104
-
-
79151472357
-
Treadmill exercise prevents decline in spatial learning and memory in APP/PS1 transgenic mice through improvement of hippocampal long-term potentiation
-
Liu H.L., Zhao G., Cai K., Zhao H.H., Shi L.D. Treadmill exercise prevents decline in spatial learning and memory in APP/PS1 transgenic mice through improvement of hippocampal long-term potentiation. Behav. Brain Res. 2011, 218:308-314.
-
(2011)
Behav. Brain Res.
, vol.218
, pp. 308-314
-
-
Liu, H.L.1
Zhao, G.2
Cai, K.3
Zhao, H.H.4
Shi, L.D.5
-
105
-
-
84883691894
-
Long-term treadmill exercise inhibits the progression of Alzheimer's disease-like neuropathology in the hippocampus of APP/PS1 transgenic mice
-
Liu H.L., Zhao G., Zhang H., Shi L.D. Long-term treadmill exercise inhibits the progression of Alzheimer's disease-like neuropathology in the hippocampus of APP/PS1 transgenic mice. Behav. Brain Res. 2013, 256:261-272.
-
(2013)
Behav. Brain Res.
, vol.256
, pp. 261-272
-
-
Liu, H.L.1
Zhao, G.2
Zhang, H.3
Shi, L.D.4
-
106
-
-
85006299250
-
Peripherally triggered and GSK-3beta-driven brain inflammation differentially skew adult hippocampal neurogenesis, behavioral pattern separation and microglial activation in response to ibuprofen
-
Llorens-Martin M., Jurado-Arjona J., Fuster-Matanzo A., Hernandez F., Rabano A., Avila J. Peripherally triggered and GSK-3beta-driven brain inflammation differentially skew adult hippocampal neurogenesis, behavioral pattern separation and microglial activation in response to ibuprofen. Transl. Psychiatry 2014, 4:e463.
-
(2014)
Transl. Psychiatry
, vol.4
, pp. e463
-
-
Llorens-Martin, M.1
Jurado-Arjona, J.2
Fuster-Matanzo, A.3
Hernandez, F.4
Rabano, A.5
Avila, J.6
-
107
-
-
84873701571
-
Treadmill exercise induces age-related changes in aversive memory, neuroinflammatory and epigenetic processes in the rat hippocampus
-
Lovatel G.A., Elsner V.R., Bertoldi K., Vanzella C., Moyses Fdos S., Vizuete A., Spindler C., Cechinel L.R., Netto C.A., Muotri A.R., Siqueira I.R. Treadmill exercise induces age-related changes in aversive memory, neuroinflammatory and epigenetic processes in the rat hippocampus. Neurobiol. Learn. Mem. 2013, 101:94-102.
-
(2013)
Neurobiol. Learn. Mem.
, vol.101
, pp. 94-102
-
-
Lovatel, G.A.1
Elsner, V.R.2
Bertoldi, K.3
Vanzella, C.4
Moyses Fdos, S.5
Vizuete, A.6
Spindler, C.7
Cechinel, L.R.8
Netto, C.A.9
Muotri, A.R.10
Siqueira, I.R.11
-
108
-
-
84940759126
-
Regulation of adult neurogenesis and plasticity by (Early) stress, glucocorticoids, and inflammation
-
Lucassen P.J., Oomen C.A., Naninck E.F., Fitzsimons C.P., van Dam A.M., Czeh B., Korosi A. Regulation of adult neurogenesis and plasticity by (Early) stress, glucocorticoids, and inflammation. Cold Spring Harbor Perspect. Biol. 2015, 7:a021303.
-
(2015)
Cold Spring Harbor Perspect. Biol.
, vol.7
, pp. a021303
-
-
Lucassen, P.J.1
Oomen, C.A.2
Naninck, E.F.3
Fitzsimons, C.P.4
van Dam, A.M.5
Czeh, B.6
Korosi, A.7
-
110
-
-
84860901234
-
Running throughout middle-age improves memory function, hippocampal neurogenesis, and BDNF levels in female C57BL/6J mice
-
Marlatt M.W., Potter M.C., Lucassen P.J., van Praag H. Running throughout middle-age improves memory function, hippocampal neurogenesis, and BDNF levels in female C57BL/6J mice. Dev. Neurobiol. 2012, 72:943-952.
-
(2012)
Dev. Neurobiol.
, vol.72
, pp. 943-952
-
-
Marlatt, M.W.1
Potter, M.C.2
Lucassen, P.J.3
van Praag, H.4
-
111
-
-
84885435490
-
Prolonged running, not fluoxetine treatment, increases neurogenesis, but does not alter neuropathology, in the 3xTg mouse model of Alzheimer's disease
-
Marlatt M.W., Potter M.C., Bayer T.A., van Praag H., Lucassen P.J. Prolonged running, not fluoxetine treatment, increases neurogenesis, but does not alter neuropathology, in the 3xTg mouse model of Alzheimer's disease. Curr. Top. Behav. Nneurosci. 2013, 15:313-340.
-
(2013)
Curr. Top. Behav. Nneurosci.
, vol.15
, pp. 313-340
-
-
Marlatt, M.W.1
Potter, M.C.2
Bayer, T.A.3
van Praag, H.4
Lucassen, P.J.5
-
112
-
-
84924390130
-
TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus
-
Matsuda T., Murao N., Katano Y., Juliandi B., Kohyama J., Akira S., Kawai T., Nakashima K. TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus. Nat. Commun. 2015, 6:6514.
-
(2015)
Nat. Commun.
, vol.6
, pp. 6514
-
-
Matsuda, T.1
Murao, N.2
Katano, Y.3
Juliandi, B.4
Kohyama, J.5
Akira, S.6
Kawai, T.7
Nakashima, K.8
-
113
-
-
84947080762
-
Neuro-immune dysfunction during brain aging: new insights in microglial cell regulation
-
Matt S.M., Johnson R.W. Neuro-immune dysfunction during brain aging: new insights in microglial cell regulation. Curr. Opin. Pharmacol. 2016, 26:96-101.
-
(2016)
Curr. Opin. Pharmacol.
, vol.26
, pp. 96-101
-
-
Matt, S.M.1
Johnson, R.W.2
-
114
-
-
84885456046
-
The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy
-
McGeer P.L., McGeer E.G. The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy. Acta Neuropathol. (Berl.) 2013, 126:479-497.
-
(2013)
Acta Neuropathol. (Berl.)
, vol.126
, pp. 479-497
-
-
McGeer, P.L.1
McGeer, E.G.2
-
115
-
-
84907483716
-
The current state of the neurogenic theory of depression and anxiety
-
Miller B.R., Hen R. The current state of the neurogenic theory of depression and anxiety. Curr. Opin. Neurobiol. 2015, 30:51-58.
-
(2015)
Curr. Opin. Neurobiol.
, vol.30
, pp. 51-58
-
-
Miller, B.R.1
Hen, R.2
-
116
-
-
84903371932
-
Age-associated dysregulation of microglial activation is coupled with enhanced blood-brain barrier permeability and pathology in APP/PS1 mice
-
Minogue A.M., Jones R.S., Kelly R.J., McDonald C.L., Connor T.J., Lynch M.A. Age-associated dysregulation of microglial activation is coupled with enhanced blood-brain barrier permeability and pathology in APP/PS1 mice. Neurobiol. Aging 2014, 35:1442-1452.
-
(2014)
Neurobiol. Aging
, vol.35
, pp. 1442-1452
-
-
Minogue, A.M.1
Jones, R.S.2
Kelly, R.J.3
McDonald, C.L.4
Connor, T.J.5
Lynch, M.A.6
-
117
-
-
69349090064
-
Age effects on the regulation of adult hippocampal neurogenesis by physical activity and environmental enrichment in the APP23 mouse model of Alzheimer disease
-
Mirochnic S., Wolf S., Staufenbiel M., Kempermann G. Age effects on the regulation of adult hippocampal neurogenesis by physical activity and environmental enrichment in the APP23 mouse model of Alzheimer disease. Hippocampus 2009, 19:1008-1018.
-
(2009)
Hippocampus
, vol.19
, pp. 1008-1018
-
-
Mirochnic, S.1
Wolf, S.2
Staufenbiel, M.3
Kempermann, G.4
-
118
-
-
84958160282
-
Gene expression in the aging human brain: an overview
-
Mohan A., Mather K.A., Thalamuthu A., Baune B.T., Sachdev P.S. Gene expression in the aging human brain: an overview. Curr. Opin. Psychiatry 2016, 29:159-167.
-
(2016)
Curr. Opin. Psychiatry
, vol.29
, pp. 159-167
-
-
Mohan, A.1
Mather, K.A.2
Thalamuthu, A.3
Baune, B.T.4
Sachdev, P.S.5
-
119
-
-
0345189366
-
Inflammatory blockade restores adult hippocampal neurogenesis
-
Monje M.L., Toda H., Palmer T.D. Inflammatory blockade restores adult hippocampal neurogenesis. Science (New York, N. Y.) 2003, 302:1760-1765.
-
(2003)
Science (New York, N. Y.)
, vol.302
, pp. 1760-1765
-
-
Monje, M.L.1
Toda, H.2
Palmer, T.D.3
-
120
-
-
84902298760
-
Impaired hippocampal neurogenesis and its enhancement with ghrelin in 5XFAD mice
-
Moon M., Cha M.Y., Mook-Jung I. Impaired hippocampal neurogenesis and its enhancement with ghrelin in 5XFAD mice. J. Alzheimers Dis. 2014, 41:233-241.
-
(2014)
J. Alzheimers Dis.
, vol.41
, pp. 233-241
-
-
Moon, M.1
Cha, M.Y.2
Mook-Jung, I.3
-
121
-
-
84947556460
-
A spectrum of exercise training reduces soluble Abeta in a dose-dependent manner in a mouse model of Alzheimer's disease
-
Moore K.M., Girens R.E., Larson S.K., Jones M.R., Restivo J.L., Holtzman D.M., Cirrito J.R., Yuede C.M., Zimmerman S.D., Timson B.F. A spectrum of exercise training reduces soluble Abeta in a dose-dependent manner in a mouse model of Alzheimer's disease. Neurobiol. Dis. 2015, 85:218-224.
-
(2015)
Neurobiol. Dis.
, vol.85
, pp. 218-224
-
-
Moore, K.M.1
Girens, R.E.2
Larson, S.K.3
Jones, M.R.4
Restivo, J.L.5
Holtzman, D.M.6
Cirrito, J.R.7
Yuede, C.M.8
Zimmerman, S.D.9
Timson, B.F.10
-
122
-
-
0034213718
-
High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation
-
Mucke L., Masliah E., Yu G.Q., Mallory M., Rockenstein E.M., Tatsuno G., Hu K., Kholodenko D., Johnson-Wood K., McConlogue L. High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J. Neurosci. 2000, 20:4050-4058.
-
(2000)
J. Neurosci.
, vol.20
, pp. 4050-4058
-
-
Mucke, L.1
Masliah, E.2
Yu, G.Q.3
Mallory, M.4
Rockenstein, E.M.5
Tatsuno, G.6
Hu, K.7
Kholodenko, D.8
Johnson-Wood, K.9
McConlogue, L.10
-
123
-
-
84864024224
-
Aerobic exercise is the critical variable in an enriched environment that increases hippocampal neurogenesis and water maze learning in male C57BL/6J mice
-
Mustroph M.L., Chen S., Desai S.C., Cay E.B., DeYoung E.K., Rhodes J.S. Aerobic exercise is the critical variable in an enriched environment that increases hippocampal neurogenesis and water maze learning in male C57BL/6J mice. Neuroscience 2012, 219:62-71.
-
(2012)
Neuroscience
, vol.219
, pp. 62-71
-
-
Mustroph, M.L.1
Chen, S.2
Desai, S.C.3
Cay, E.B.4
DeYoung, E.K.5
Rhodes, J.S.6
-
124
-
-
0037427384
-
Astrocytes accumulate A beta 42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains
-
Nagele R.G., D'Andrea M.R., Lee H., Venkataraman V., Wang H.Y. Astrocytes accumulate A beta 42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains. Brain Res. 2003, 971:197-209.
-
(2003)
Brain Res.
, vol.971
, pp. 197-209
-
-
Nagele, R.G.1
D'Andrea, M.R.2
Lee, H.3
Venkataraman, V.4
Wang, H.Y.5
-
125
-
-
17644413209
-
Extended voluntary running inhibits exercise-induced adult hippocampal progenitor proliferation in the spontaneously hypertensive rat
-
Naylor A.S., Persson A.I., Eriksson P.S., Jonsdottir I.H., Thorlin T. Extended voluntary running inhibits exercise-induced adult hippocampal progenitor proliferation in the spontaneously hypertensive rat. J. Neurophysiol. 2005, 93:2406-2414.
-
(2005)
J. Neurophysiol.
, vol.93
, pp. 2406-2414
-
-
Naylor, A.S.1
Persson, A.I.2
Eriksson, P.S.3
Jonsdottir, I.H.4
Thorlin, T.5
-
126
-
-
34848862114
-
Three weeks of running wheel exposure improves cognitive performance in the aged Tg2576 mouse
-
Nichol K.E., Parachikova A.I., Cotman C.W. Three weeks of running wheel exposure improves cognitive performance in the aged Tg2576 mouse. Behav. Brain Res. 2007, 184:124-132.
-
(2007)
Behav. Brain Res.
, vol.184
, pp. 124-132
-
-
Nichol, K.E.1
Parachikova, A.I.2
Cotman, C.W.3
-
127
-
-
84871798259
-
Suppression of adult neurogenesis impairs population coding of similar contexts in hippocampal CA3 region
-
Niibori Y., Yu T.S., Epp J.R., Akers K.G., Josselyn S.A., Frankland P.W. Suppression of adult neurogenesis impairs population coding of similar contexts in hippocampal CA3 region. Nat. Commun. 2012, 3:1253.
-
(2012)
Nat. Commun.
, vol.3
, pp. 1253
-
-
Niibori, Y.1
Yu, T.S.2
Epp, J.R.3
Akers, K.G.4
Josselyn, S.A.5
Frankland, P.W.6
-
128
-
-
84888188543
-
Inflammation and immune system activation in aging: a mathematical approach
-
Nikas J.B. Inflammation and immune system activation in aging: a mathematical approach. Sci. Rep. 2013, 3:3254.
-
(2013)
Sci. Rep.
, vol.3
, pp. 3254
-
-
Nikas, J.B.1
-
129
-
-
33749521100
-
Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation
-
Oakley H., Cole S.L., Logan S., Maus E., Shao P., Craft J., Guillozet-Bongaarts A., Ohno M., Disterhoft J., Van Eldik L., Berry R., Vassar R. Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation. J. Neurosci. 2006, 26:10129-10140.
-
(2006)
J. Neurosci.
, vol.26
, pp. 10129-10140
-
-
Oakley, H.1
Cole, S.L.2
Logan, S.3
Maus, E.4
Shao, P.5
Craft, J.6
Guillozet-Bongaarts, A.7
Ohno, M.8
Disterhoft, J.9
Van Eldik, L.10
Berry, R.11
Vassar, R.12
-
130
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction
-
Oddo S., Caccamo A., Shepherd J.D., Murphy M.P., Golde T.E., Kayed R., Metherate R., Mattson M.P., Akbari Y., LaFerla F.M. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 2003, 39:409-421.
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
LaFerla, F.M.10
-
131
-
-
84906501534
-
Adult hippocampal neurogenesis and its role in cognition
-
Oomen C.A., Bekinschtein P., Kent B.A., Saksida L.M., Bussey T.J. Adult hippocampal neurogenesis and its role in cognition. Wiley Interdiscip. Rev. Cogn. Sci. 2014, 5:573-587.
-
(2014)
Wiley Interdiscip. Rev. Cogn. Sci.
, vol.5
, pp. 573-587
-
-
Oomen, C.A.1
Bekinschtein, P.2
Kent, B.A.3
Saksida, L.M.4
Bussey, T.J.5
-
133
-
-
40849112965
-
Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition
-
Parachikova A., Nichol K.E., Cotman C.W. Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition. Neurobiol. Dis. 2008, 30:121-129.
-
(2008)
Neurobiol. Dis.
, vol.30
, pp. 121-129
-
-
Parachikova, A.1
Nichol, K.E.2
Cotman, C.W.3
-
134
-
-
0021270573
-
Neurons generated in the adult brain are recruited into functional circuits
-
Paton J.A., Nottebohm F.N. Neurons generated in the adult brain are recruited into functional circuits. Science 1984, 225:1046-1048.
-
(1984)
Science
, vol.225
, pp. 1046-1048
-
-
Paton, J.A.1
Nottebohm, F.N.2
-
135
-
-
84888244437
-
Long-term exercise is needed to enhance synaptic plasticity in the hippocampus
-
Patten A.R., Sickmann H., Hryciw B.N., Kucharsky T., Parton R., Kernick A., Christie B.R. Long-term exercise is needed to enhance synaptic plasticity in the hippocampus. Learn. Mem. 2013, 20:642-647.
-
(2013)
Learn. Mem.
, vol.20
, pp. 642-647
-
-
Patten, A.R.1
Sickmann, H.2
Hryciw, B.N.3
Kucharsky, T.4
Parton, R.5
Kernick, A.6
Christie, B.R.7
-
136
-
-
34248375311
-
An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus
-
Pereira A.C., Huddleston D.E., Brickman A.M., Sosunov A.A., Hen R., McKhann G.M., Sloan R., Gage F.H., Brown T.R., Small S.A. An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:5638-5643.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 5638-5643
-
-
Pereira, A.C.1
Huddleston, D.E.2
Brickman, A.M.3
Sosunov, A.A.4
Hen, R.5
McKhann, G.M.6
Sloan, R.7
Gage, F.H.8
Brown, T.R.9
Small, S.A.10
-
137
-
-
84861691381
-
Neurogenic abnormalities in Alzheimer's disease differ between stages of neurogenesis and are partly related to cholinergic pathology
-
Perry E.K., Johnson M., Ekonomou A., Perry R.H., Ballard C., Attems J. Neurogenic abnormalities in Alzheimer's disease differ between stages of neurogenesis and are partly related to cholinergic pathology. Neurobiol. Dis. 2012, 47:155-162.
-
(2012)
Neurobiol. Dis.
, vol.47
, pp. 155-162
-
-
Perry, E.K.1
Johnson, M.2
Ekonomou, A.3
Perry, R.H.4
Ballard, C.5
Attems, J.6
-
138
-
-
84881546426
-
Impact of N-tau on adult hippocampal neurogenesis, anxiety, and memory
-
Pristera A., Saraulli D., Farioli-Vecchioli S., Strimpakos G., Costanzi M., di Certo M.G., Cannas S., Ciotti M.T., Tirone F., Mattei E., Cestari V., Canu N. Impact of N-tau on adult hippocampal neurogenesis, anxiety, and memory. Neurobiol. Aging 2013, 34:2551-2563.
-
(2013)
Neurobiol. Aging
, vol.34
, pp. 2551-2563
-
-
Pristera, A.1
Saraulli, D.2
Farioli-Vecchioli, S.3
Strimpakos, G.4
Costanzi, M.5
di Certo, M.G.6
Cannas, S.7
Ciotti, M.T.8
Tirone, F.9
Mattei, E.10
Cestari, V.11
Canu, N.12
-
139
-
-
84954091440
-
Mindfulness in the maintenance of cognitive capacities in Alzheimer's disease: a randomized clinical trial
-
Quintana-Hernandez D.J., Miro-Barrachina M.T., Ibanez-Fernandez I.J., Pino A.S., Quintana-Montesdeoca M.P., Rodriguez-de Vera B., Morales-Casanova D., Perez-Vieitez Mdel C., Rodriguez-Garcia J., Bravo-Caraduje N. Mindfulness in the maintenance of cognitive capacities in Alzheimer's disease: a randomized clinical trial. J. Alzheimers Dis. 2015, 50:217-232.
-
(2015)
J. Alzheimers Dis.
, vol.50
, pp. 217-232
-
-
Quintana-Hernandez, D.J.1
Miro-Barrachina, M.T.2
Ibanez-Fernandez, I.J.3
Pino, A.S.4
Quintana-Montesdeoca, M.P.5
Rodriguez-de Vera, B.6
Morales-Casanova, D.7
Perez-Vieitez Mdel, C.8
Rodriguez-Garcia, J.9
Bravo-Caraduje, N.10
-
140
-
-
33751229947
-
The window and mechanisms of major age-related decline in the production of new neurons within the dentate gyrus of the hippocampus
-
Rao M.S., Hattiangady B., Shetty A.K. The window and mechanisms of major age-related decline in the production of new neurons within the dentate gyrus of the hippocampus. Aging Cell 2006, 5:545-558.
-
(2006)
Aging Cell
, vol.5
, pp. 545-558
-
-
Rao, M.S.1
Hattiangady, B.2
Shetty, A.K.3
-
141
-
-
43249111260
-
Physical activity and dementia risk in the elderly: findings from a prospective Italian study
-
Ravaglia G., Forti P., Lucicesare A., Pisacane N., Rietti E., Bianchin M., Dalmonte E. Physical activity and dementia risk in the elderly: findings from a prospective Italian study. Neurology 2008, 70:1786-1794.
-
(2008)
Neurology
, vol.70
, pp. 1786-1794
-
-
Ravaglia, G.1
Forti, P.2
Lucicesare, A.3
Pisacane, N.4
Rietti, E.5
Bianchin, M.6
Dalmonte, E.7
-
142
-
-
31144475277
-
Exercise-induced changes in dendritic structure and complexity in the adult hippocampal dentate gyrus
-
Redila V.A., Christie B.R. Exercise-induced changes in dendritic structure and complexity in the adult hippocampal dentate gyrus. Neuroscience 2006, 137:1299-1307.
-
(2006)
Neuroscience
, vol.137
, pp. 1299-1307
-
-
Redila, V.A.1
Christie, B.R.2
-
143
-
-
84949183854
-
Improved cardiorespiratory fitness is associated with increased cortical thickness in mild cognitive impairment
-
Reiter K., Nielson K.A., Smith T.J., Weiss L.R., Alfini A.J., Smith J.C. Improved cardiorespiratory fitness is associated with increased cortical thickness in mild cognitive impairment. J. Int. Neuropsychol. Soc.: JINS 2015, 21:757-767.
-
(2015)
J. Int. Neuropsychol. Soc.: JINS
, vol.21
, pp. 757-767
-
-
Reiter, K.1
Nielson, K.A.2
Smith, T.J.3
Weiss, L.R.4
Alfini, A.J.5
Smith, J.C.6
-
144
-
-
84894180246
-
Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain
-
Revilla S., Sunol C., Garcia-Mesa Y., Gimenez-Llort L., Sanfeliu C., Cristofol R. Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain. Neuropharmacology 2014, 81:55-63.
-
(2014)
Neuropharmacology
, vol.81
, pp. 55-63
-
-
Revilla, S.1
Sunol, C.2
Garcia-Mesa, Y.3
Gimenez-Llort, L.4
Sanfeliu, C.5
Cristofol, R.6
-
145
-
-
0035889404
-
Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta (1-42)
-
Rockenstein E., Mallory M., Mante M., Sisk A., Masliaha E. Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta (1-42). J. Neurosci. Res. 2001, 66:573-582.
-
(2001)
J. Neurosci. Res.
, vol.66
, pp. 573-582
-
-
Rockenstein, E.1
Mallory, M.2
Mante, M.3
Sisk, A.4
Masliaha, E.5
-
146
-
-
51849123324
-
Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease
-
Rodriguez J.J., Jones V.C., Tabuchi M., Allan S.M., Knight E.M., LaFerla F.M., Oddo S., Verkhratsky A. Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease. PLoS One 2008, 3:e2935.
-
(2008)
PLoS One
, vol.3
, pp. e2935
-
-
Rodriguez, J.J.1
Jones, V.C.2
Tabuchi, M.3
Allan, S.M.4
Knight, E.M.5
LaFerla, F.M.6
Oddo, S.7
Verkhratsky, A.8
-
147
-
-
77949491472
-
Increase in the density of resting microglia precedes neuritic plaque formation and microglial activation in a transgenic model of Alzheimer's disease
-
Rodriguez J.J., Witton J., Olabarria M., Noristani H.N., Verkhratsky A. Increase in the density of resting microglia precedes neuritic plaque formation and microglial activation in a transgenic model of Alzheimer's disease. Cell Death Dis. 2010, 1:e1.
-
(2010)
Cell Death Dis.
, vol.1
, pp. e1
-
-
Rodriguez, J.J.1
Witton, J.2
Olabarria, M.3
Noristani, H.N.4
Verkhratsky, A.5
-
148
-
-
80054060635
-
Voluntary running and environmental enrichment restores impaired hippocampal neurogenesis in a triple transgenic mouse model of Alzheimer's disease
-
Rodriguez J.J., Noristani H.N., Olabarria M., Fletcher J., Somerville T.D., Yeh C.Y., Verkhratsky A. Voluntary running and environmental enrichment restores impaired hippocampal neurogenesis in a triple transgenic mouse model of Alzheimer's disease. Curr. Alzheimer Res. 2011, 8:707-717.
-
(2011)
Curr. Alzheimer Res.
, vol.8
, pp. 707-717
-
-
Rodriguez, J.J.1
Noristani, H.N.2
Olabarria, M.3
Fletcher, J.4
Somerville, T.D.5
Yeh, C.Y.6
Verkhratsky, A.7
-
149
-
-
33644516288
-
Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms
-
Sastre M., Klockgether T., Heneka M.T. Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms. Int. J. Dev. Neurosci. 2006, 24:167-176.
-
(2006)
Int. J. Dev. Neurosci.
, vol.24
, pp. 167-176
-
-
Sastre, M.1
Klockgether, T.2
Heneka, M.T.3
-
150
-
-
33751213392
-
Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus
-
Saxe M.D., Battaglia F., Wang J.-W.W., Malleret G., David D.J., Monckton J.E., Garcia A.D., Sofroniew M.V., Kandel E.R., Santarelli L., Hen R., Drew M.R. Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:17501-17506.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 17501-17506
-
-
Saxe, M.D.1
Battaglia, F.2
Wang, J.-W.W.3
Malleret, G.4
David, D.J.5
Monckton, J.E.6
Garcia, A.D.7
Sofroniew, M.V.8
Kandel, E.R.9
Santarelli, L.10
Hen, R.11
Drew, M.R.12
-
151
-
-
33746652117
-
Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits
-
Schindowski K., Bretteville A., Leroy K., Begard S., Brion J.P., Hamdane M., Buee L. Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits. Am. J. Pathol. 2006, 169:599-616.
-
(2006)
Am. J. Pathol.
, vol.169
, pp. 599-616
-
-
Schindowski, K.1
Bretteville, A.2
Leroy, K.3
Begard, S.4
Brion, J.P.5
Hamdane, M.6
Buee, L.7
-
152
-
-
34347387536
-
Tau-4R suppresses proliferation and promotes neuronal differentiation in the hippocampus of tau knockin/knockout mice
-
Sennvik K., Boekhoorn K., Lasrado R., Terwel D., Verhaeghe S., Korr H., Schmitz C., Tomiyama T., Mori H., Krugers H., Joels M., Ramakers G.J., Lucassen P.J., Van Leuven F. Tau-4R suppresses proliferation and promotes neuronal differentiation in the hippocampus of tau knockin/knockout mice. FASEB J. 2007, 21:2149-2161.
-
(2007)
FASEB J.
, vol.21
, pp. 2149-2161
-
-
Sennvik, K.1
Boekhoorn, K.2
Lasrado, R.3
Terwel, D.4
Verhaeghe, S.5
Korr, H.6
Schmitz, C.7
Tomiyama, T.8
Mori, H.9
Krugers, H.10
Joels, M.11
Ramakers, G.J.12
Lucassen, P.J.13
Van Leuven, F.14
-
153
-
-
84948712806
-
Involvement of inflammation in Alzheimer's disease pathogenesis and therapeutic potential of anti-inflammatory agents
-
Shadfar S., Hwang C.J., Lim M.S., Choi D.Y., Hong J.T. Involvement of inflammation in Alzheimer's disease pathogenesis and therapeutic potential of anti-inflammatory agents. Arch. Pharmacal Res. 2015, 38:2106-2119.
-
(2015)
Arch. Pharmacal Res.
, vol.38
, pp. 2106-2119
-
-
Shadfar, S.1
Hwang, C.J.2
Lim, M.S.3
Choi, D.Y.4
Hong, J.T.5
-
154
-
-
0035868717
-
Neurogenesis in the adult is involved in the formation of trace memories
-
Shors T.J., Miesegaes G., Beylin A., Zhao M., Rydel T., Gould E. Neurogenesis in the adult is involved in the formation of trace memories. Nature 2001, 410:372-376.
-
(2001)
Nature
, vol.410
, pp. 372-376
-
-
Shors, T.J.1
Miesegaes, G.2
Beylin, A.3
Zhao, M.4
Rydel, T.5
Gould, E.6
-
155
-
-
84892450175
-
Targeting neurogenesis ameliorates danger assessment in a mouse model of Alzheimer's disease
-
Shruster A., Offen D. Targeting neurogenesis ameliorates danger assessment in a mouse model of Alzheimer's disease. Behav. Brain Res. 2014, 261:193-201.
-
(2014)
Behav. Brain Res.
, vol.261
, pp. 193-201
-
-
Shruster, A.1
Offen, D.2
-
156
-
-
11844289586
-
A role for adult neurogenesis in spatial long-term memory
-
Snyder J.S., Hong N.S., McDonald R.J., Wojtowicz J.M. A role for adult neurogenesis in spatial long-term memory. Neuroscience 2005, 130:843-852.
-
(2005)
Neuroscience
, vol.130
, pp. 843-852
-
-
Snyder, J.S.1
Hong, N.S.2
McDonald, R.J.3
Wojtowicz, J.M.4
-
157
-
-
84878831768
-
Dynamics of hippocampal neurogenesis in adult humans
-
Spalding K.L., Bergmann O., Alkass K., Bernard S., Salehpour M., Huttner H.B., Boström E., Westerlund I., Vial C., Buchholz B.A., Possnert G., Mash D.C., Druid H., Frisén J. Dynamics of hippocampal neurogenesis in adult humans. Cell 2013, 153:1219-1227.
-
(2013)
Cell
, vol.153
, pp. 1219-1227
-
-
Spalding, K.L.1
Bergmann, O.2
Alkass, K.3
Bernard, S.4
Salehpour, M.5
Huttner, H.B.6
Boström, E.7
Westerlund, I.8
Vial, C.9
Buchholz, B.A.10
Possnert, G.11
Mash, D.C.12
Druid, H.13
Frisén, J.14
-
158
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
-
Sturchler-Pierrat C., Abramowski D., Duke M., Wiederhold K.H., Mistl C., Rothacher S., Ledermann B., Burki K., Frey P., Paganetti P.A., Waridel C., Calhoun M.E., Jucker M., Probst A., Staufenbiel M., Sommer B. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc. Natl. Acad. Sci. U. S. A. 1997, 94:13287-13292.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramowski, D.2
Duke, M.3
Wiederhold, K.H.4
Mistl, C.5
Rothacher, S.6
Ledermann, B.7
Burki, K.8
Frey, P.9
Paganetti, P.A.10
Waridel, C.11
Calhoun, M.E.12
Jucker, M.13
Probst, A.14
Staufenbiel, M.15
Sommer, B.16
-
159
-
-
37349128902
-
Decreased proliferation of hippocampal progenitor cells in APPswe/PS1dE9 transgenic mice
-
Taniuchi N., Niidome T., Goto Y., Akaike A., Kihara T., Sugimoto H. Decreased proliferation of hippocampal progenitor cells in APPswe/PS1dE9 transgenic mice. Neuroreport 2007, 18:1801-1805.
-
(2007)
Neuroreport
, vol.18
, pp. 1801-1805
-
-
Taniuchi, N.1
Niidome, T.2
Goto, Y.3
Akaike, A.4
Kihara, T.5
Sugimoto, H.6
-
160
-
-
84955677869
-
Voluntary running attenuates memory loss, decreases neuropathological changes and induces neurogenesis in a mouse model of Alzheimer's disease
-
Tapia-Rojas C., Aranguiz F., Varela-Nallar L., Inestrosa N.C. Voluntary running attenuates memory loss, decreases neuropathological changes and induces neurogenesis in a mouse model of Alzheimer's disease. Brain Pathol. (Zurich, Switzerland) 2016, 26:62-74.
-
(2016)
Brain Pathol. (Zurich, Switzerland)
, vol.26
, pp. 62-74
-
-
Tapia-Rojas, C.1
Aranguiz, F.2
Varela-Nallar, L.3
Inestrosa, N.C.4
-
161
-
-
0141740742
-
Intrathecal inflammation precedes development of Alzheimer's disease
-
Tarkowski E., Andreasen N., Tarkowski A., Blennow K. Intrathecal inflammation precedes development of Alzheimer's disease. J. Neurol. Neurosurg. Psychiatry 2003, 74:1200-1205.
-
(2003)
J. Neurol. Neurosurg. Psychiatry
, vol.74
, pp. 1200-1205
-
-
Tarkowski, E.1
Andreasen, N.2
Tarkowski, A.3
Blennow, K.4
-
162
-
-
34547824397
-
EGb 761 enhances adult hippocampal neurogenesis and phosphorylation of CREB in transgenic mouse model of Alzheimer's disease
-
Tchantchou F., Xu Y., Wu Y., Christen Y., Luo Y. EGb 761 enhances adult hippocampal neurogenesis and phosphorylation of CREB in transgenic mouse model of Alzheimer's disease. FASEB J. 2007, 21:2400-2408.
-
(2007)
FASEB J.
, vol.21
, pp. 2400-2408
-
-
Tchantchou, F.1
Xu, Y.2
Wu, Y.3
Christen, Y.4
Luo, Y.5
-
163
-
-
78650309919
-
Treadmill exercise represses neuronal cell death in an aged transgenic mouse model of Alzheimer's disease
-
Um H.S., Kang E.B., Koo J.H., Kim H.T., Jin L., Kim E.J., Yang C.H., An G.Y., Cho I.H., Cho J.Y. Treadmill exercise represses neuronal cell death in an aged transgenic mouse model of Alzheimer's disease. Neurosci. Res. 2011, 69:161-173.
-
(2011)
Neurosci. Res.
, vol.69
, pp. 161-173
-
-
Um, H.S.1
Kang, E.B.2
Koo, J.H.3
Kim, H.T.4
Jin, L.5
Kim, E.J.6
Yang, C.H.7
An, G.Y.8
Cho, I.H.9
Cho, J.Y.10
-
164
-
-
79951789939
-
Short-term environmental enrichment rescues adult neurogenesis and memory deficits in APP(Sw,Ind) transgenic mice
-
Valero J., Espana J., Parra-Damas A., Martin E., Rodriguez-Alvarez J., Saura C.A. Short-term environmental enrichment rescues adult neurogenesis and memory deficits in APP(Sw,Ind) transgenic mice. PLoS One 2011, 6:e16832.
-
(2011)
PLoS One
, vol.6
, pp. e16832
-
-
Valero, J.1
Espana, J.2
Parra-Damas, A.3
Martin, E.4
Rodriguez-Alvarez, J.5
Saura, C.A.6
-
165
-
-
2342442488
-
Cognitive and behavioural effects of music-based exercises in patients with dementia
-
Van de Winckel A., Feys H., De Weerdt W., Dom R. Cognitive and behavioural effects of music-based exercises in patients with dementia. Clin. Rehabil. 2004, 18:253-260.
-
(2004)
Clin. Rehabil.
, vol.18
, pp. 253-260
-
-
Van de Winckel, A.1
Feys, H.2
De Weerdt, W.3
Dom, R.4
-
166
-
-
67949114536
-
Physical exercise leads to rapid adaptations in hippocampal vasculature: temporal dynamics and relationship to cell proliferation and neurogenesis
-
Van der Borght K., Kobor-Nyakas D.E., Klauke K., Eggen B.J., Nyakas C., Van der Zee E.A., Meerlo P. Physical exercise leads to rapid adaptations in hippocampal vasculature: temporal dynamics and relationship to cell proliferation and neurogenesis. Hippocampus 2009, 19:928-936.
-
(2009)
Hippocampus
, vol.19
, pp. 928-936
-
-
Van der Borght, K.1
Kobor-Nyakas, D.E.2
Klauke, K.3
Eggen, B.J.4
Nyakas, C.5
Van der Zee, E.A.6
Meerlo, P.7
-
167
-
-
80054905928
-
Six-month walking program changes cognitive and ADL performance in patients with Alzheimer
-
Venturelli M., Scarsini R., Schena F. Six-month walking program changes cognitive and ADL performance in patients with Alzheimer. Am. J. Alzheimer's Dis. Other Demen. 2011, 26:381-388.
-
(2011)
Am. J. Alzheimer's Dis. Other Demen.
, vol.26
, pp. 381-388
-
-
Venturelli, M.1
Scarsini, R.2
Schena, F.3
-
168
-
-
84969791903
-
Vulnerability of calbindin, calretinin and parvalbumin in a transgenic/knock-in APPswe/PS1dE9 mouse model of Alzheimer disease together with disruption of hippocampal neurogenesis
-
Verdaguer E., Brox S., Petrov D., Olloquequi J., Romero R., de Lemos M.L., Camins A., Auladell C. Vulnerability of calbindin, calretinin and parvalbumin in a transgenic/knock-in APPswe/PS1dE9 mouse model of Alzheimer disease together with disruption of hippocampal neurogenesis. Exp. Gerontol. 2015, 69:176-188.
-
(2015)
Exp. Gerontol.
, vol.69
, pp. 176-188
-
-
Verdaguer, E.1
Brox, S.2
Petrov, D.3
Olloquequi, J.4
Romero, R.5
de Lemos, M.L.6
Camins, A.7
Auladell, C.8
-
169
-
-
36749010157
-
Mature astrocytes in the adult human neocortex express the early neuronal marker doublecortin
-
Verwer R.W., Sluiter A.A., Balesar R.A., Baayen J.C., Noske D.P., Dirven C.M., Wouda J., van Dam A.M., Lucassen P.J., Swaab D.F. Mature astrocytes in the adult human neocortex express the early neuronal marker doublecortin. Brain: A J. Neurol. 2007, 130:3321-3335.
-
(2007)
Brain: A J. Neurol.
, vol.130
, pp. 3321-3335
-
-
Verwer, R.W.1
Sluiter, A.A.2
Balesar, R.A.3
Baayen, J.C.4
Noske, D.P.5
Dirven, C.M.6
Wouda, J.7
van Dam, A.M.8
Lucassen, P.J.9
Swaab, D.F.10
-
170
-
-
84905491643
-
Neurologic impairment following closed head injury predicts post-traumatic neurogenesis
-
Villasana L.E., Westbrook G.L., Schnell E. Neurologic impairment following closed head injury predicts post-traumatic neurogenesis. Exp. Neurol. 2014, 261:156-162.
-
(2014)
Exp. Neurol.
, vol.261
, pp. 156-162
-
-
Villasana, L.E.1
Westbrook, G.L.2
Schnell, E.3
-
171
-
-
84857051992
-
A community-based exercise programme to improve functional ability in people with Alzheimer's disease: a randomized controlled trial
-
Vreugdenhil A., Cannell J., Davies A., Razay G. A community-based exercise programme to improve functional ability in people with Alzheimer's disease: a randomized controlled trial. Scand. J. Caring Sci. 2012, 26:12-19.
-
(2012)
Scand. J. Caring Sci.
, vol.26
, pp. 12-19
-
-
Vreugdenhil, A.1
Cannell, J.2
Davies, A.3
Razay, G.4
-
172
-
-
84921489093
-
Beneficial effects of dietary EGCG and voluntary exercise on behavior in an Alzheimer's disease mouse model
-
Walker J.M., Klakotskaia D., Ajit D., Weisman G.A., Wood W.G., Sun G.Y., Serfozo P., Simonyi A., Schachtman T.R. Beneficial effects of dietary EGCG and voluntary exercise on behavior in an Alzheimer's disease mouse model. J. Alzheimers Dis. 2015, 44:561-572.
-
(2015)
J. Alzheimers Dis.
, vol.44
, pp. 561-572
-
-
Walker, J.M.1
Klakotskaia, D.2
Ajit, D.3
Weisman, G.A.4
Wood, W.G.5
Sun, G.Y.6
Serfozo, P.7
Simonyi, A.8
Schachtman, T.R.9
-
173
-
-
33645096734
-
Inhibition of neurogenesis interferes with hippocampus-dependent memory function
-
Winocur G., Wojtowicz J.M., Sekeres M., Snyder J.S., Wang S. Inhibition of neurogenesis interferes with hippocampus-dependent memory function. Hippocampus 2006, 16:296-304.
-
(2006)
Hippocampus
, vol.16
, pp. 296-304
-
-
Winocur, G.1
Wojtowicz, J.M.2
Sekeres, M.3
Snyder, J.S.4
Wang, S.5
-
174
-
-
84887468128
-
Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway
-
Wrann C.D., White J.P., Salogiannis J., Laznik-Bogoslavski D., Wu J., Ma D., Lin J.D., Greenberg M.E., Spiegelman B.M. Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway. Cell Metab. 2013, 18:649-659.
-
(2013)
Cell Metab.
, vol.18
, pp. 649-659
-
-
Wrann, C.D.1
White, J.P.2
Salogiannis, J.3
Laznik-Bogoslavski, D.4
Wu, J.5
Ma, D.6
Lin, J.D.7
Greenberg, M.E.8
Spiegelman, B.M.9
-
175
-
-
57349113992
-
2008: Exercise enhances the proliferation of neural stem cells and neurite growth and survival of neuronal progenitor cells in dentate gyrus of middle-aged mice
-
Wu C.W., Chang Y.T., Yu L., Chen H.I., Jen C.J., Wu S.Y., Lo C.P., Kuo Y.M. 2008: Exercise enhances the proliferation of neural stem cells and neurite growth and survival of neuronal progenitor cells in dentate gyrus of middle-aged mice. J. Appl. Physiol. 1985, 105:1585-1594.
-
(1985)
J. Appl. Physiol.
, vol.105
, pp. 1585-1594
-
-
Wu, C.W.1
Chang, Y.T.2
Yu, L.3
Chen, H.I.4
Jen, C.J.5
Wu, S.Y.6
Lo, C.P.7
Kuo, Y.M.8
-
176
-
-
84884816645
-
Aerobic exercise combined with antioxidative treatment does not counteract moderate- or mid-stage Alzheimer-like pathophysiology of APP/PS1 mice
-
Xu Z.Q., Zhang L.Q., Wang Q., Marshall C., Xiao N., Gao J.Y., Wu T., Ding J., Hu G., Xiao M. Aerobic exercise combined with antioxidative treatment does not counteract moderate- or mid-stage Alzheimer-like pathophysiology of APP/PS1 mice. CNS Neurosci. Ther. 2013, 19:795-803.
-
(2013)
CNS Neurosci. Ther.
, vol.19
, pp. 795-803
-
-
Xu, Z.Q.1
Zhang, L.Q.2
Wang, Q.3
Marshall, C.4
Xiao, N.5
Gao, J.Y.6
Wu, T.7
Ding, J.8
Hu, G.9
Xiao, M.10
-
177
-
-
84900001780
-
Physical exercise-induced adult neurogenesis: a good strategy to prevent cognitive decline in neurodegenerative diseases?
-
Yau S.Y., Gil-Mohapel J., Christie B.R., So K.F. Physical exercise-induced adult neurogenesis: a good strategy to prevent cognitive decline in neurodegenerative diseases?. BioMed. Res. Int. 2014, 2014:403120.
-
(2014)
BioMed. Res. Int.
, vol.2014
, pp. 403120
-
-
Yau, S.Y.1
Gil-Mohapel, J.2
Christie, B.R.3
So, K.F.4
-
178
-
-
71849113134
-
Increased hippocampal neurogenesis in the progressive stage of Alzheimer's disease phenotype in an APP/PS1 double transgenic mouse model
-
Yu Y., He J., Zhang Y., Luo H., Zhu S., Yang Y., Zhao T., Wu J., Huang Y., Kong J., Tan Q., Li X.M. Increased hippocampal neurogenesis in the progressive stage of Alzheimer's disease phenotype in an APP/PS1 double transgenic mouse model. Hippocampus 2009, 19:1247-1253.
-
(2009)
Hippocampus
, vol.19
, pp. 1247-1253
-
-
Yu, Y.1
He, J.2
Zhang, Y.3
Luo, H.4
Zhu, S.5
Yang, Y.6
Zhao, T.7
Wu, J.8
Huang, Y.9
Kong, J.10
Tan, Q.11
Li, X.M.12
-
179
-
-
36049023544
-
Inflammation, obesity, and the metabolic syndrome
-
Yudkin J.S. Inflammation, obesity, and the metabolic syndrome. Horm. Metab. Res. 2007, 39:707-709.
-
(2007)
Horm. Metab. Res.
, vol.39
, pp. 707-709
-
-
Yudkin, J.S.1
-
180
-
-
68149150846
-
Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease
-
Yuede C.M., Zimmerman S.D., Dong H., Kling M.J., Bero A.W., Holtzman D.M., Timson B.F., Csernansky J.G. Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease. Neurobiol. Dis. 2009, 35:426-432.
-
(2009)
Neurobiol. Dis.
, vol.35
, pp. 426-432
-
-
Yuede, C.M.1
Zimmerman, S.D.2
Dong, H.3
Kling, M.J.4
Bero, A.W.5
Holtzman, D.M.6
Timson, B.F.7
Csernansky, J.G.8
-
181
-
-
84871612985
-
Enhanced expression of glia maturation factor correlates with glial activation in the brain of triple transgenic Alzheimer's disease mice
-
Zaheer S., Thangavel R., Wu Y., Khan M.M., Kempuraj D., Zaheer A. Enhanced expression of glia maturation factor correlates with glial activation in the brain of triple transgenic Alzheimer's disease mice. Neurochem. Res. 2013, 38:218-225.
-
(2013)
Neurochem. Res.
, vol.38
, pp. 218-225
-
-
Zaheer, S.1
Thangavel, R.2
Wu, Y.3
Khan, M.M.4
Kempuraj, D.5
Zaheer, A.6
-
182
-
-
84887612242
-
Benefits of multimodal exercise intervention for postural control and frontal cognitive functions in individuals with Alzheimer's disease: a controlled trial
-
de Andrade L.P., Gobbi L.T., Coelho F.G., Christofoletti G., Costa J.L., Stella F. Benefits of multimodal exercise intervention for postural control and frontal cognitive functions in individuals with Alzheimer's disease: a controlled trial. J. Am. Geriatr. Soc. 2013, 61:1919-1926.
-
(2013)
J. Am. Geriatr. Soc.
, vol.61
, pp. 1919-1926
-
-
de Andrade, L.P.1
Gobbi, L.T.2
Coelho, F.G.3
Christofoletti, G.4
Costa, J.L.5
Stella, F.6
-
183
-
-
0033539607
-
Running enhances neurogenesis, learning, and long-term potentiation in mice
-
van Praag H., Christie B.R., Sejnowski T.J., Gage F.H. Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:13427-13431.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 13427-13431
-
-
van Praag, H.1
Christie, B.R.2
Sejnowski, T.J.3
Gage, F.H.4
-
184
-
-
0033360314
-
Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
-
van Praag H., Kempermann G., Gage F.H. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat. Neurosci. 1999, 2:266-270.
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 266-270
-
-
van Praag, H.1
Kempermann, G.2
Gage, F.H.3
-
186
-
-
84929459427
-
Treadmill exercise enhances synaptic plasticity, but does not alter beta-amyloid deposition in hippocampi of aged APP/PS1 transgenic mice
-
Zhao G., Liu H.L., Zhang H., Tong X.J. Treadmill exercise enhances synaptic plasticity, but does not alter beta-amyloid deposition in hippocampi of aged APP/PS1 transgenic mice. Neuroscience 2015, 298:357-366.
-
(2015)
Neuroscience
, vol.298
, pp. 357-366
-
-
Zhao, G.1
Liu, H.L.2
Zhang, H.3
Tong, X.J.4
|