Human tau expression reduces adult neurogenesis in a mouse model of tauopathy

Neurobiology of Aging

Volumn 36, Issue 6, 2015, Pages 2034-2042

  Komuro, Yutaro ^a   Xu, Guixiang ^a   Bhaskar, Kiran ^b   Lamb, Bruce T ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

Adult neurogenesis; HTau; MAPT; Mouse; Tau; Tauopathy

Indexed keywords

TAU PROTEIN; MAPT PROTEIN, HUMAN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN REGION; CELL PROLIFERATION; CONTROLLED STUDY; DENTATE GYRUS; DISEASE COURSE; HIPPOCAMPUS; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SUBVENTRICULAR ZONE; TAUOPATHY; ANIMAL; CELL CULTURE; CYTOLOGY; DISEASE MODEL; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROTEINOSIS; TRANSGENIC MOUSE;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HIPPOCAMPUS; HUMANS; MICE, KNOCKOUT; MICE, TRANSGENIC; NEUROGENESIS; NEURONS; PHOSPHORYLATION; PROTEIN AGGREGATION, PATHOLOGICAL; TAU PROTEINS; TAUOPATHIES;

EID: 84929281851     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2015.03.002     Document Type: Article

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