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Volumn 15, Issue 11, 2004, Pages 1751-1754

Environmental enrichment improves cognition in aged Alzheimer's transgenic mice despite stable β-amyloid deposition

Author keywords

Amyloid deposition; Alzheimer's disease; APPsw transgenic mice; Cognitive performance; Discriminant function analysis; Environmental enrichment

Indexed keywords

AMYLOID BETA PROTEIN;

EID: 4043147336     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.wnr.0000137183.68847.4e     Document Type: Article
Times cited : (204)

References (18)
  • 1
    • 0037010310 scopus 로고    scopus 로고
    • Effects of enriched environments with different durations and starting times on learning capacity during aging in rats assessed by a refined procedure of the Hebb-Williams maze task
    • Kobayashi S, Ohashi Y and Ando S. Effects of enriched environments with different durations and starting times on learning capacity during aging in rats assessed by a refined procedure of the Hebb-Williams maze task. J Neurosci Res 2002; 70:340-346.
    • (2002) J Neurosci Res , vol.70 , pp. 340-346
    • Kobayashi, S.1    Ohashi, Y.2    Ando, S.3
  • 2
    • 0034910779 scopus 로고    scopus 로고
    • Environmental enrichment: Effects on spatial memory and hippocampal CREB immunoreactivity
    • Williams B, Luo Y, Ward C, Redd K, Gibson R, Kuczaj S et al. Environmental enrichment: effects on spatial memory and hippocampal CREB immunoreactivity. Physiol Behav 2001; 73:649-658.
    • (2001) Physiol Behav , vol.73 , pp. 649-658
    • Williams, B.1    Luo, Y.2    Ward, C.3    Redd, K.4    Gibson, R.5    Kuczaj, S.6
  • 3
    • 0036325981 scopus 로고    scopus 로고
    • Neuroplasticity in old age: Sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment
    • Kempermann G, Gast D and Gage FH. Neuroplasticity in old age: sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment. Ann Neurol 2002; 52:135-143.
    • (2002) Ann Neurol , vol.52 , pp. 135-143
    • Kempermann, G.1    Gast, D.2    Gage, F.H.3
  • 5
    • 0033914032 scopus 로고    scopus 로고
    • Long-term environmental enrichment leads to regional increases in neurotrophin levels in rat brain
    • Ickes B, Pham T, Sanders L, Albeck D, Mohammed A and Granhom A. Long-term environmental enrichment leads to regional increases in neurotrophin levels in rat brain. Exp Neurol 2000; 164:45-52.
    • (2000) Exp Neurol , vol.164 , pp. 45-52
    • Ickes, B.1    Pham, T.2    Sanders, L.3    Albeck, D.4    Mohammed, A.5    Granhom, A.6
  • 7
    • 0035853155 scopus 로고    scopus 로고
    • Patients with Alzheimer's disease have reduced activities in midlife compared with healthy control-group members
    • Friedland R, Fritsh T, Smyth K, Koss E, Lerner A, Chen C-H et al. Patients with Alzheimer's disease have reduced activities in midlife compared with healthy control-group members. Proc Natl Acad Sci USA 2001; 98:3440-3445.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3440-3445
    • Friedland, R.1    Fritsh, T.2    Smyth, K.3    Koss, E.4    Lerner, A.5    Chen, C.-H.6
  • 8
    • 0032910570 scopus 로고    scopus 로고
    • Are sex and educational level independent predictors of dementia and Alzheimer's disease? Incidence data from the PAQUID project
    • Letenneur L, Gilleron V, Commenges D, Helmer C, Orgogozo J and Dartigues J. Are sex and educational level independent predictors of dementia and Alzheimer's disease? Incidence data from the PAQUID project. J Neurol Neurosurg Psychiatry 1999; 66:177-183.
    • (1999) J Neurol Neurosurg Psychiatry , vol.66 , pp. 177-183
    • Letenneur, L.1    Gilleron, V.2    Commenges, D.3    Helmer, C.4    Orgogozo, J.5    Dartigues, J.6
  • 9
    • 0035111689 scopus 로고    scopus 로고
    • Cognitive intervention in Alzheimer disease: A randomized placebo-controlled study
    • Davis R, Massman P and Doody R. Cognitive intervention in Alzheimer disease: a randomized placebo-controlled study. Alzheimer Dis Assoc Disorders 2001; 15:1-9.
    • (2001) Alzheimer Dis Assoc Disorders , vol.15 , pp. 1-9
    • Davis, R.1    Massman, P.2    Doody, R.3
  • 11
    • 3042858051 scopus 로고    scopus 로고
    • Cognitive rehabilitation of mildly impaired Alzheimer's disease patients on cholinesterase inhibitors
    • in press
    • Loewenstein DA, Acavedo A, Czaja S and Duara R. Cognitive rehabilitation of mildly impaired Alzheimer's disease patients on cholinesterase inhibitors. Am J Geriatr Psychiatry 2004 (in press).
    • (2004) Am J Geriatr Psychiatry
    • Loewenstein, D.A.1    Acavedo, A.2    Czaja, S.3    Duara, R.4
  • 12
    • 0035830686 scopus 로고    scopus 로고
    • Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precurson protein and presenilin-1 transgenes
    • Arendash GW, King DL, Gordon MN, Morgan D, Hatcher JM, Hope CE et al. Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precurson protein and presenilin-1 transgenes. Brain Res 2001; 891:42-53.
    • (2001) Brain Res , vol.891 , pp. 42-53
    • Arendash, G.W.1    King, D.L.2    Gordon, M.N.3    Morgan, D.4    Hatcher, J.M.5    Hope, C.E.6
  • 13
    • 0035282790 scopus 로고    scopus 로고
    • α-1-Antichymotrypsin promotes β-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease
    • Nilsson LNG, Bales KR, DiCarlo G, Gordon MN, Morgan D, Paul SM et al. α-1-Antichymotrypsin promotes β-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease. J Neurosci 2001; 21:1444-1451.
    • (2001) J Neurosci , vol.21 , pp. 1444-1451
    • Nilsson, L.N.G.1    Bales, K.R.2    DiCarlo, G.3    Gordon, M.N.4    Morgan, D.5    Paul, S.M.6
  • 14
    • 84984755327 scopus 로고    scopus 로고
    • Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
    • Morgan D, Diamond D, Gottschall PE, Ugen KE, Dickey C, Hardy J et al. Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 2000; 408:982-985.
    • (2000) Nature , vol.408 , pp. 982-985
    • Morgan, D.1    Diamond, D.2    Gottschall, P.E.3    Ugen, K.E.4    Dickey, C.5    Hardy, J.6
  • 15
    • 0037736704 scopus 로고    scopus 로고
    • Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model
    • Joseph JA, Denisova NA, Arendash GW, Gordon M, Diamond D, Shukitt-Hale B et al. Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr Neurosci 2003; 6:153-162.
    • (2003) Nutr Neurosci , vol.6 , pp. 153-162
    • Joseph, J.A.1    Denisova, N.A.2    Arendash, G.W.3    Gordon, M.4    Diamond, D.5    Shukitt-Hale, B.6
  • 16
    • 4043104729 scopus 로고    scopus 로고
    • Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation
    • (in press) doi: 10.1016j.neurobiolaging.2003.12.011
    • Nilsson LNG, Arendash GW, Leighty RE, Costa DA, Low MA, Garcia MF et al. Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation. Neurobiol Aging 2004 (in press) doi: 10.1016j.neurobiolaging.2003.12. 011.
    • (2004) Neurobiol Aging
    • Nilsson, L.N.G.1    Arendash, G.W.2    Leighty, R.E.3    Costa, D.A.4    Low, M.A.5    Garcia, M.F.6
  • 17
    • 2442587216 scopus 로고    scopus 로고
    • Multi-metric behavioral comparison of APPsw and P301L models for Alzheimer's disease; linkage of poorer cognitive performance to tau pathology in forebrain
    • Arendash GW, Lewis J, Leighty R, McGowan E, Cracchiolo J, Hutton M et al. Multi-metric behavioral comparison of APPsw and P301L models for Alzheimer's disease; linkage of poorer cognitive performance to tau pathology in forebrain. Brain Res 2004; 1012:29-41.
    • (2004) Brain Res , vol.1012 , pp. 29-41
    • Arendash, G.W.1    Lewis, J.2    Leighty, R.3    McGowan, E.4    Cracchiolo, J.5    Hutton, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.