-
1
-
-
84858702953
-
The ageing cortical synapse: Hallmarks and implications for cognitive decline
-
Morrison, J. H. & Baxter, M. G. The ageing cortical synapse: hallmarks and implications for cognitive decline. Nat. Rev. Neurosci. 13, 240-250 (2012).
-
(2012)
Nat. Rev. Neurosci.
, vol.13
, pp. 240-250
-
-
Morrison, J.H.1
Baxter, M.G.2
-
2
-
-
77950229880
-
Neural mechanisms of ageing and cognitive decline
-
Bishop, N. A., Lu, T. & Yankner, B. A. Neural mechanisms of ageing and cognitive decline. Nature 464, 529-535 (2010).
-
(2010)
Nature
, vol.464
, pp. 529-535
-
-
Bishop, N.A.1
Lu, T.2
Yankner, B.A.3
-
3
-
-
0037242125
-
Aging and the human neocortex
-
DOI 10.1016/S0531-5565(02)00151-1, PII S0531556502001511
-
Pakkenberg, B. et al. Aging and the human neocortex. Exp. Gerontol. 38, 95-99 (2003). (Pubitemid 36110503)
-
(2003)
Experimental Gerontology
, vol.38
, Issue.1-2
, pp. 95-99
-
-
Pakkenberg, B.1
Pelvig, D.2
Marner, L.3
Bundgaard, M.J.4
Gundersen, H.J.G.5
Nyengaard, J.R.6
Regeur, L.7
-
4
-
-
78650911563
-
Genomic and proteomic strategies to identify novel targets potentially involved in learning and memory
-
Benoit, C. E., Rowe, W. B., Menard, C., Sarret, P. & Quirion, R. Genomic and proteomic strategies to identify novel targets potentially involved in learning and memory. Trends Pharmacol. Sci. 32, 43-52 (2011).
-
(2011)
Trends Pharmacol. Sci.
, vol.32
, pp. 43-52
-
-
Benoit, C.E.1
Rowe, W.B.2
Menard, C.3
Sarret, P.4
Quirion, R.5
-
5
-
-
55749105400
-
Gene expression changes in the course of normal brain aging are sexually dimorphic
-
Berchtold, N. C. et al.Gene expression changes in the course of normal brain aging are sexually dimorphic. Proc. Natl. Acad. Sci. USA 105, 15605-15610 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 15605-15610
-
-
Berchtold, N.C.1
-
6
-
-
80755142832
-
Mathematical prognostic biomarker models for treatment response and survival in epithelial ovarian cancer
-
Nikas, J. B., Boylan, K. L., Skubitz, A. P. & Low, W. C. Mathematical prognostic biomarker models for treatment response and survival in epithelial ovarian cancer. Cancer Inform. 10, 233-247 (2011).
-
(2011)
Cancer Inform.
, vol.10
, pp. 233-247
-
-
Nikas, J.B.1
Boylan, K.L.2
Skubitz, A.P.3
Low, W.C.4
-
7
-
-
84863903537
-
Prognosis of treatment response (pathological complete response) in breast cancer
-
Nikas, J. B., Low, W. C. & Burgio, P. A. Prognosis of treatment response (pathological complete response) in breast cancer. Biomark. Insights 7, 59-70 (2012).
-
(2012)
Biomark. Insights
, vol.7
, pp. 59-70
-
-
Nikas, J.B.1
Low, W.C.2
Burgio, P.A.3
-
8
-
-
33644783812
-
Regional and cellular gene expression changes in human Huntington's disease brain
-
DOI 10.1093/hmg/ddl013
-
Hodges, A. et al. Regional and cellular gene expression changes in human Huntington's disease brain. Hum. Mol. Genet. 15, 965-977 (2006). (Pubitemid 43338237)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.6
, pp. 965-977
-
-
Hodges, A.1
Strand, A.D.2
Aragaki, A.K.3
Kuhn, A.4
Sengstag, T.5
Hughes, G.6
Elliston, L.A.7
Hartog, C.8
Goldstein, D.R.9
Thu, D.10
Hollingsworth, Z.R.11
Collin, F.12
Synek, B.13
Holmans, P.A.14
Young, A.B.15
Wexler, N.S.16
Delorenzi, M.17
Kooperberg, C.18
Augood, S.J.19
Faull, R.L.M.20
Olson, J.M.21
Jones, L.22
Luthi-Carter, R.23
more..
-
9
-
-
0026447529
-
Complement activation by beta-amyloid in Alzheimer disease
-
Rogers, J. et al. Complement activation by beta-amyloid in Alzheimer disease. Proc. Natl. Acad. Sci. U.S.A. 89, 10016-10020 (1992).
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 10016-10020
-
-
Rogers, J.1
-
10
-
-
38949125934
-
Identification of arthritis-related gene clusters by microarray analysis of two independent mouse models for rheumatoid arthritis
-
Fujikado, N., Saijo, S. & Iwakura, Y. Identification of arthritis-related gene clusters by microarray analysis of two independent mouse models for rheumatoid arthritis. Arthritis Res. Ther. 8, R100 (2006).
-
(2006)
Arthritis Res. Ther.
, vol.8
-
-
Fujikado, N.1
Saijo, S.2
Iwakura, Y.3
-
11
-
-
14544288232
-
2A receptor antagonists in Parkinson's disease
-
DOI 10.1016/j.pharmthera.2004.10.007
-
Xu, K., Bastia, E. & Schwarzschild, M. Therapeutic potential of adenosine A(2A) receptor antagonists in Parkinson's disease. Pharmacol. Ther. 105, 267-310 (2005). (Pubitemid 40297894)
-
(2005)
Pharmacology and Therapeutics
, vol.105
, Issue.3
, pp. 267-310
-
-
Xu, K.1
Bastia, E.2
Schwarzschild, M.3
-
12
-
-
0036882256
-
3 adenosine receptors in human astrocytoma cells: Agonist-mediated desensitization, internalization, and down-regulation
-
DOI 10.1124/mol.62.6.1373
-
Trincavelli, M. L. et al. A3 adenosine receptors in human astrocytoma cells: agonist-mediated desensitization, internalization, and down-regulation. Mol. Pharmacol. 62, 1373-1384 (2002). (Pubitemid 35403832)
-
(2002)
Molecular Pharmacology
, vol.62
, Issue.6
, pp. 1373-1384
-
-
Trincavelli, M.L.1
Tuscano, D.2
Marroni, M.3
Falleni, A.4
Gremigni, V.5
Ceruti, S.6
Abbracchio, M.P.7
Jacobson, K.A.8
Cattabeni, F.9
Martini, C.10
-
13
-
-
25844526181
-
Gene expression in Huntington's disease skeletal muscle: A potential biomarker
-
DOI 10.1093/hmg/ddi192
-
Strand, A. D. et al. Gene expression in Huntington's disease skeletal muscle: a potential biomarker. Hum. Mol. Genet. 14, 1863-1876 (2005). (Pubitemid 41418057)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.13
, pp. 1863-1876
-
-
Strand, A.D.1
Aragaki, A.K.2
Shaw, D.3
Bird, T.4
Holton, J.5
Turner, C.6
Tapscott, S.J.7
Tabrizi, S.J.8
Schapira, A.H.9
Kooperberg, C.10
Olson, J.M.11
-
14
-
-
33751020244
-
The future of genomic profiling of neurological diseases using blood
-
DOI 10.1001/archneur.63.11.1529
-
Sharp, F. R. et al. The future of genomic profiling of neurological diseases using blood. Arch. Neurol. 63, 1529-1536 (2006). (Pubitemid 44748794)
-
(2006)
Archives of Neurology
, vol.63
, Issue.11
, pp. 1529-1536
-
-
Sharp, F.R.1
Xu, H.2
Lit, L.3
Walker, W.4
Apperson, M.5
Gilbert, D.L.6
Glauser, T.A.7
Wong, B.8
Hershey, A.9
Liu, D.-Z.10
Pinter, J.11
Zhan, X.12
Liu, X.13
Ran, R.14
-
15
-
-
33845303956
-
Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis
-
DOI 10.1172/JCI28756
-
Rangel-Moreno, J. et al. Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis. J. Clin. Invest. 116, 3183-3194 (2006). (Pubitemid 44878632)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.12
, pp. 3183-3194
-
-
Rangel-Moreno, J.1
Hartson, L.2
Navarro, C.3
Gaxiola, M.4
Selman, M.5
Randall, T.D.6
-
16
-
-
0037222114
-
Primary mediastinal B-cell lymphoma: High frequency of BCL-6 mutations and consistent expression of the transcription factors OCT-2, BOB.1, and PU.1 in the absence of immunoglobulins
-
Pileri, S. A. et al. Primary mediastinal B-cell lymphoma: high frequency of BCL-6 mutations and consistent expression of the transcription factors OCT-2, BOB.1, and PU.1 in the absence of immunoglobulins. Am. J. Pathol. 162, 243-253 (2003). (Pubitemid 36042006)
-
(2003)
American Journal of Pathology
, vol.162
, Issue.1
, pp. 243-253
-
-
Pileri, S.A.1
Gaidano, G.2
Zinzani, P.L.3
Falini, B.4
Gaulard, P.5
Zucca, E.6
Pieri, F.7
Berra, E.8
Sabattini, E.9
Ascani, S.10
Piccioli, M.11
Johnson, P.W.M.12
Giardini, R.13
Pescarmona, E.14
Novero, D.15
Piccaluga, P.P.16
Marafioti, T.17
Alonso, M.A.18
Cavalli, F.19
-
17
-
-
33846536952
-
Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus
-
Li, Y. et al. Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus. J. Immunol. 178, 1938-1947 (2007). (Pubitemid 46154667)
-
(2007)
Journal of Immunology
, vol.178
, Issue.3
, pp. 1938-1947
-
-
Li, Y.1
Harada, T.2
Juang, Y.-T.3
Kyttaris, V.C.4
Wang, Y.5
Zidanic, M.6
Tung, K.7
Tsokos, G.C.8
-
18
-
-
84877616476
-
MicroRNA regulate immunological pathways in T-cells in immune thrombocytopenia (ITP)
-
Jemas, M., Nookaew, I., Wadenvik, H. & Olsson, B. MicroRNA regulate immunological pathways in T-cells in immune thrombocytopenia (ITP) Blood 121, 2095-2098 (2013).
-
(2013)
Blood
, vol.121
, pp. 2095-2098
-
-
Jemas, M.1
Nookaew, I.2
Wadenvik, H.3
Olsson, B.4
-
19
-
-
0030728056
-
CD44 expression is aberrant in benign Schwann cell tumors possessing mutations in the neurofibromatosis type 2, but not type 1, gene
-
Sherman, L. et al. CD44 expression is aberrant in benign Schwann cell tumors possessing mutations in the neurofibromatosis type 2, but not type 1, gene. Cancer Res. 57, 4889-4897 (1997). (Pubitemid 27468999)
-
(1997)
Cancer Research
, vol.57
, Issue.21
, pp. 4889-4897
-
-
Sherman, L.1
Jacoby, L.B.2
Lampe, J.3
Pelton, P.4
Aguzzi, A.5
Herrlich, P.6
Ponta, H.7
-
20
-
-
19944419885
-
Expression profile of immune response genes in patients with Severe Acute Respiratory Syndrome
-
Reghunathan, R. et al. Expression profile of immune response genes in patients with Severe Acute Respiratory Syndrome. BMC Immunol. 6, 2
-
BMC Immunol.
, vol.6
, pp. 2
-
-
Reghunathan, R.1
-
21
-
-
33750488768
-
Complement regulates inhalation tolerance at the dendritic cell/T cell interface
-
DOI 10.1016/j.molimm.2006.06.016, PII S0161589006002197
-
Kohl, J. & Wills-Karp, M. Complement regulates inhalation tolerance at the dendritic cell/T cell interface. Mol. Immunol. 44, 44-56 (2007). (Pubitemid 44647103)
-
(2007)
Molecular Immunology
, vol.44
, Issue.1-3
, pp. 44-56
-
-
Kohl, J.1
Wills-Karp, M.2
-
22
-
-
77951836633
-
Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis
-
Baranzini, S. E. et al. Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis. Nature 464, 1351-1356 (2010).
-
(2010)
Nature
, vol.464
, pp. 1351-1356
-
-
Baranzini, S.E.1
-
24
-
-
0037444212
-
CDNA microarray analysis of individual Duchenne muscular dystrophy patients
-
Nogutsi, S. et al. cDNA microarray analysis of individual Duchenne muscular dystrophy patients. Hum. Mol. Genet. 12, 595-600 (2003).
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 595-600
-
-
Nogutsi, S.1
-
25
-
-
0036850422
-
Immune response gene expression increases in the aging murine hippocampus
-
DOI 10.1016/S0165-5728(02)00317-X, PII S016557280200317X
-
Terao, A. et al. Immune response gene expression increases in the aging murine hippocampus. J. Neuroimmunol. 132, 99-112 (2002). (Pubitemid 35333331)
-
(2002)
Journal of Neuroimmunology
, vol.132
, Issue.1-2
, pp. 99-112
-
-
Terao, A.1
Apte-Deshpande, A.2
Dousman, L.3
Morairty, S.4
Eynon, B.P.5
Kilduff, T.S.6
Freund, Y.R.7
-
26
-
-
0036132452
-
Gene expression profiling of aging using DNA microarrays
-
DOI 10.1016/S0047-6374(01)00344-X, PII S004763740100344X
-
Weindruch, R., Kayo, T., Lee, C. K. & Prolla, T. A. Gene expression profiling of aging using DNA microarrays. Mech. Ageing Dev. 123, 177-193 (2002). (Pubitemid 33097564)
-
(2002)
Mechanisms of Ageing and Development
, vol.123
, Issue.2-3
, pp. 177-193
-
-
Weindruch, R.1
Kayo, T.2
Lee, C.-K.3
Prolla, T.A.4
-
27
-
-
77953218064
-
Synaptic correlates of increased cognitive vulnerability with aging: Peripheral immune challenge and aging interact to disrupt theta-burst late-phase long-term potentiation in hippocampal area CA1
-
Chapman, T. R., Barrientos, R. M., Ahrendsen, J. T., Maier, S. F. & Patterson, S. L. Synaptic correlates of increased cognitive vulnerability with aging: peripheral immune challenge and aging interact to disrupt theta-burst late-phase long-term potentiation in hippocampal area CA1. J. Neurosci. 30, 7598-7603 (2010).
-
(2010)
J. Neurosci.
, vol.30
, pp. 7598-7603
-
-
Chapman, T.R.1
Barrientos, R.M.2
Ahrendsen, J.T.3
Maier, S.F.4
Patterson, S.L.5
-
28
-
-
77953483260
-
Age-related neuroinflammatory changes negatively impact on neuronal function
-
Lynch, M. A. Age-related neuroinflammatory changes negatively impact on neuronal function. Front. Aging Neurosci. 1(6), (2010).
-
(2010)
Front. Aging Neurosci.
, vol.1
, pp. 6
-
-
Lynch, M.A.1
-
29
-
-
84862835163
-
Neuroinflammation and synaptic loss
-
Rao, J. S., Kellom, M., Kim, H. W. & Rapoport, S. I. Neuroinflammation and synaptic loss. Neurochem. Res. 37, 903-910 (2012).
-
(2012)
Neurochem. Res.
, vol.37
, pp. 903-910
-
-
Rao, J.S.1
Kellom, M.2
Kim, H.W.3
Rapoport, S.I.4
-
30
-
-
0034279244
-
Circuitspecific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats
-
Smith, T. D., Adams, M. M., Gallagher, M.,Morrison, J. H. & Rapp, P. R. Circuitspecific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats. J. Neurosci. 20, 6587-6593 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 6587-6593
-
-
Smith, T.D.1
Adams, M.M.2
Gallagher, M.3
Morrison, J.H.4
Rapp, P.R.5
-
31
-
-
3042631024
-
Gene regulation and DNA damage in the ageing human brain
-
DOI 10.1038/nature02661
-
Lu, T. et al. Gene regulation and DNA damage in the ageing human brain. Nature 429, 883-891 (2004). (Pubitemid 38843301)
-
(2004)
Nature
, vol.429
, Issue.6994
, pp. 883-891
-
-
Lu, T.1
Pan, Y.2
Kao, S.-Y.3
Li, C.4
Kohane, I.5
Chan, J.6
Yankner, B.A.7
-
32
-
-
0000847978
-
Gene-expression profile of the ageing brain in mice
-
DOI 10.1038/77046
-
Lee, C. K., Weindruch, R. & Prolla, T. A. Gene-expression profile of the ageing brain in mice. Nat. Genet. 25, 294-297 (2000). (Pubitemid 30437315)
-
(2000)
Nature Genetics
, vol.25
, Issue.3
, pp. 294-297
-
-
Lee, C.-K.1
Weindruch, R.2
Prolla, T.A.3
-
34
-
-
1242338796
-
Aging, spatial learning, and total synapse number in the rat CA1 stratum radiatum
-
DOI 10.1016/j.neurobiolaging.2003.12.001
-
Geinisman, Y. et al. Aging, spatial learning, and total synapse number in the rat CA1 stratum radiatum. Neurobiol. Aging 25, 407-416 (2004). (Pubitemid 38220975)
-
(2004)
Neurobiology of Aging
, vol.25
, Issue.3
, pp. 407-416
-
-
Geinisman, Y.1
Ganeshina, O.2
Yoshida, R.3
Berry, R.W.4
Disterhoft, J.F.5
Gallagher, M.6
-
35
-
-
43149102747
-
Protective effects of NSAIDs on the development of Alzheimer disease
-
DOI 10.1212/01.wnl.0000311269.57716.63, PII 0000611420080506000006
-
Vlad, S. C., Miller, D. R., Kowall, N. W. & Felson, D. T. Protective effects of NSAIDs on the development of Alzheimer disease. Neurology 70, 1672-1677 (2008). (Pubitemid 351644133)
-
(2008)
Neurology
, vol.70
, Issue.19
, pp. 1672-1677
-
-
Vlad, S.C.1
Miller, D.R.2
Kowall, N.W.3
Felson, D.T.4
-
36
-
-
44949084672
-
Relation of NSAIDs to incident AD, change in cognitive function, and AD pathology
-
Arvanitakis, Z. et al. Relation of NSAIDs to incident AD, change in cognitive function, and AD pathology. Neurology 70, 2219-2225 (2008).
-
(2008)
Neurology
, vol.70
, pp. 2219-2225
-
-
Arvanitakis, Z.1
-
37
-
-
84872088087
-
Variant of TREM2 associated with the risk of Alzheimer's disease
-
Jonsson, T. et al.Variant of TREM2 associated with the risk of Alzheimer's disease. N. Engl. J. Med. 368, 107-116 (2013).
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 107-116
-
-
Jonsson, T.1
-
38
-
-
77957902250
-
Comparison of analytical mathematical approaches for identifying key nuclear magnetic resonance spectroscopy biomarkers in the diagnosis and assessment of clinical change of diseases
-
Nikas, J. B., Keene, C. D. & Low, W. C. Comparison of analytical mathematical approaches for identifying key nuclear magnetic resonance spectroscopy biomarkers in the diagnosis and assessment of clinical change of diseases. J. Comp. Neurol. 518, 4091-4112 (2010).
-
(2010)
J. Comp. Neurol.
, vol.518
, pp. 4091-4112
-
-
Nikas, J.B.1
Keene, C.D.2
Low, W.C.3
-
39
-
-
79952980163
-
ROC-supervised principal component analysis in connection with the diagnosis of diseases
-
Nikas, J. B. & Low, W. C. ROC-supervised principal component analysis in connection with the diagnosis of diseases. Am. J. Transl. Res. 3, 180-196 (2011).
-
(2011)
Am. J. Transl. Res.
, vol.3
, pp. 180-196
-
-
Nikas, J.B.1
Low, W.C.2
-
40
-
-
80655127860
-
Application of clustering analyses to the diagnosis of Huntington disease in mice and other diseases with well-defined group boundaries
-
Nikas, J. B. & Low, W. C. Application of clustering analyses to the diagnosis of Huntington disease in mice and other diseases with well-defined group boundaries. Comput. Methods Programs Biomed. 104, e133-e147 (2011).
-
(2011)
Comput. Methods Programs Biomed.
, vol.104
-
-
Nikas, J.B.1
Low, W.C.2
-
41
-
-
84856768568
-
Linear Discriminant Functions in Connection with the micro-RNA Diagnosis of Colon Cancer
-
Nikas, J. B. & Low,W. C. Linear Discriminant Functions in Connection with the micro-RNA Diagnosis of Colon Cancer. Cancer Inform. 11, 1-14 (2012).
-
(2012)
Cancer Inform.
, vol.11
, pp. 1-14
-
-
Nikas, J.B.1
Loww, C.2
-
42
-
-
84874188583
-
APOBEC3B is an enzymatic source of mutation in breast cancer
-
Burns, M. B. et al. APOBEC3B is an enzymatic source of mutation in breast cancer. Nature 494, 366-370 (2013).
-
(2013)
Nature
, vol.494
, pp. 366-370
-
-
Burns, M.B.1
-
43
-
-
0032542897
-
What's wrong with Bonferroni adjustments
-
Perneger, T. V. What's wrong with Bonferroni adjustments. BMJ 316, 1236-1238 (1998). (Pubitemid 28171344)
-
(1998)
British Medical Journal
, vol.316
, Issue.7139
, pp. 1236-1238
-
-
Perneger, T.V.1
-
44
-
-
3342943178
-
Do multiple outcomemeasures require p-value adjustment?
-
Feise, R. J. Do multiple outcomemeasures require p-value adjustment? BMC Med. Res. Methodol. 2, 8 (2002).
-
(2002)
BMC Med. Res. Methodol.
, vol.2
, pp. 8
-
-
Feise, R.J.1
-
46
-
-
0031236925
-
Asymptotic statistical theory of overtraining and cross-validation
-
PII S1045922797060517
-
Amari, S., Murata, N., Muller, K.-R., Finke, M. & Yang, H. H. Asymptotic Statistical Theory of Overtraining and Cross-Validation. IEEE Trans. Neural Networks 8, 985-996 (1997). (Pubitemid 127763330)
-
(1997)
IEEE Transactions on Neural Networks
, vol.8
, Issue.5
, pp. 985-996
-
-
Amari, S.-I.1
Murata, N.2
Muller, K.-R.3
Finke, M.4
Yang, H.H.5
|