-
1
-
-
84901410479
-
Mitochondria as signaling organelles
-
Chandel NS. 2014. Mitochondria as signaling organelles. BMC Biol. 12:34
-
(2014)
BMC Biol.
, vol.12
, pp. 34
-
-
Chandel, N.S.1
-
2
-
-
84895546187
-
Mitochondrial quality control and communications with the nucleus are important in maintaining mitochondrial function and cell health
-
Kotiadis VN, Duchen MR, Osellame LD. 2014. Mitochondrial quality control and communications with the nucleus are important in maintaining mitochondrial function and cell health. Biochim. Biophys. Acta 1840:1254-65
-
(2014)
Biochim. Biophys. Acta
, vol.1840
, pp. 1254-1265
-
-
Kotiadis, V.N.1
Duchen, M.R.2
Osellame, L.D.3
-
3
-
-
84887456534
-
Role of endothelial cell metabolism in vessel sprouting
-
De Bock K, Georgiadou M, Carmeliet P. 2013. Role of endothelial cell metabolism in vessel sprouting. Cell Metab. 18:634-47
-
(2013)
Cell Metab.
, vol.18
, pp. 634-647
-
-
De Bock, K.1
Georgiadou, M.2
Carmeliet, P.3
-
6
-
-
84858376953
-
Mitochondria: In sickness and in health
-
Nunnari J, Suomalainen A. 2012. Mitochondria: in sickness and in health. Cell 148:1145-59
-
(2012)
Cell
, vol.148
, pp. 1145-1159
-
-
Nunnari, J.1
Suomalainen, A.2
-
7
-
-
43249112094
-
ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis
-
Ishikawa K, Takenaga K, Akimoto M, Koshikawa N, Yamaguchi A, et al. 2008. ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis. Science 320:661-64
-
(2008)
Science
, vol.320
, pp. 661-664
-
-
Ishikawa, K.1
Takenaga, K.2
Akimoto, M.3
Koshikawa, N.4
Yamaguchi, A.5
-
8
-
-
77951736264
-
Vascular oxidative stress: The common link in hypertensive and diabetic vascular disease
-
Cohen RA, Tong X. 2010. Vascular oxidative stress: The common link in hypertensive and diabetic vascular disease. J. Cardiovasc. Pharmacol. 55:308-16
-
(2010)
J. Cardiovasc. Pharmacol.
, vol.55
, pp. 308-316
-
-
Cohen, R.A.1
Tong, X.2
-
11
-
-
84873848690
-
Myocardial ischemia-reperfusion injury: A neglected therapeutic target
-
Hausenloy DJ, YellonDM. 2013. Myocardial ischemia-reperfusion injury: A neglected therapeutic target. J. Clin. Investig. 123:92-100
-
(2013)
J. Clin. Investig.
, vol.123
, pp. 92-100
-
-
Hausenloy, D.J.1
Yellon, D.M.2
-
12
-
-
84872486948
-
Molecular mechanisms of ischemia-reperfusion injury in brain: Pivotal role of the mitochondrial membrane potential in reactive oxygen species generation
-
Sanderson TH, Reynolds CA, Kumar R, Przyklenk K, Huttemann M. 2013. Molecular mechanisms of ischemia-reperfusion injury in brain: pivotal role of the mitochondrial membrane potential in reactive oxygen species generation. Mol. Neurobiol. 47:9-23
-
(2013)
Mol. Neurobiol.
, vol.47
, pp. 9-23
-
-
Sanderson, T.H.1
Reynolds, C.A.2
Kumar, R.3
Przyklenk, K.4
Huttemann, M.5
-
14
-
-
84859708101
-
The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation
-
McGill MR, Sharpe MR, Williams CD, Taha M, Curry SC, Jaeschke H. 2012. The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation. J. Clin. Investig. 122:1574-83
-
(2012)
J. Clin. Investig.
, vol.122
, pp. 1574-1583
-
-
McGill, M.R.1
Sharpe, M.R.2
Williams, C.D.3
Taha, M.4
Curry, S.C.5
Jaeschke, H.6
-
15
-
-
84924676959
-
Pleurotus ostreatus opposes mitochondrial dysfunction and oxidative stress in acetaminophen-induced hepato-renal injury
-
Naguib YM, Azmy RM, Samaka RM, Salem MF. 2014. Pleurotus ostreatus opposes mitochondrial dysfunction and oxidative stress in acetaminophen-induced hepato-renal injury. BMC Complement. Altern. Med. 14:494
-
(2014)
BMC Complement. Altern. Med.
, vol.14
, pp. 494
-
-
Naguib, Y.M.1
Azmy, R.M.2
Samaka, R.M.3
Salem, M.F.4
-
16
-
-
84895544715
-
Mitochondrial dysfunction and complications associated with diabetes
-
Blake R, Trounce IA. 2014. Mitochondrial dysfunction and complications associated with diabetes. Biochim. Biophys. Acta 1840:1404-12
-
(2014)
Biochim. Biophys. Acta
, vol.1840
, pp. 1404-1412
-
-
Blake, R.1
Trounce, I.A.2
-
17
-
-
71749121998
-
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology
-
Moreira PI, Carvalho C, Zhu X, Smith MA, Perry G. 2010. Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochim. Biophys. Acta 1802:2-10
-
(2010)
Biochim. Biophys. Acta
, vol.1802
, pp. 2-10
-
-
Moreira, P.I.1
Carvalho, C.2
Zhu, X.3
Smith, M.A.4
Perry, G.5
-
19
-
-
84875679362
-
Mitochondria targeted therapeutic approaches in Parkinson's and Huntington's diseases
-
Chaturvedi RK, Beal MF. 2013. Mitochondria targeted therapeutic approaches in Parkinson's and Huntington's diseases. Mol. Cell Neurosci. 55:101-14
-
(2013)
Mol. Cell Neurosci.
, vol.55
, pp. 101-114
-
-
Chaturvedi, R.K.1
Beal, M.F.2
-
21
-
-
39149106144
-
Mitochondrial metabolism, redox signaling, and fusion: A mitochondria-ROS-HIF-1alpha-Kv1. 5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer
-
Archer SL, Gomberg-Maitland M, Maitland ML, Rich S, Garcia JG, Weir EK. 2008. Mitochondrial metabolism, redox signaling, and fusion: A mitochondria-ROS-HIF-1alpha-Kv1. 5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer. Am. J. Physiol. Heart Circ. Physiol. 294:H570-78
-
(2008)
Am. J. Physiol. Heart Circ. Physiol.
, vol.294
, pp. H570-H578
-
-
Archer, S.L.1
Gomberg-Maitland, M.2
Maitland, M.L.3
Rich, S.4
Garcia, J.G.5
Weir, E.K.6
-
23
-
-
34648837687
-
Induction of mitochondrial biogenesis is amaladaptive mechanism inmitochondrial cardiomyopathies
-
Sebastiani M, Giordano C, Nediani C, Travaglini C, Borchi E, et al. 2007. Induction of mitochondrial biogenesis is amaladaptive mechanism inmitochondrial cardiomyopathies. J. Am. Coll. Cardiol. 50:1362-69
-
(2007)
J. Am. Coll. Cardiol.
, vol.50
, pp. 1362-1369
-
-
Sebastiani, M.1
Giordano, C.2
Nediani, C.3
Travaglini, C.4
Borchi, E.5
-
24
-
-
77955487488
-
The science of stroke: Mechanisms in search of treatments
-
Moskowitz MA, Lo EH, Iadecola C. 2010. The science of stroke: mechanisms in search of treatments. Neuron 67:181-98
-
(2010)
Neuron
, vol.67
, pp. 181-198
-
-
Moskowitz, M.A.1
Lo, E.H.2
Iadecola, C.3
-
25
-
-
84902322007
-
Mitochondrial reactive oxygen species: A double edged sword in ischemia/reperfusion versus preconditioning
-
Kalogeris T, Bao Y, Korthuis RJ. 2014. Mitochondrial reactive oxygen species: A double edged sword in ischemia/reperfusion versus preconditioning. Redox Biol. 2:702-14
-
(2014)
Redox Biol.
, vol.2
, pp. 702-714
-
-
Kalogeris, T.1
Bao, Y.2
Korthuis, R.J.3
-
26
-
-
69149086632
-
To prevent, protect and save the ischemic heart: Antioxidants revisited
-
Andreadou I, Iliodromitis EK, Farmakis D, Kremastinos DT. 2009. To prevent, protect and save the ischemic heart: Antioxidants revisited. Expert Opin. Ther. Targets 13:945-56
-
(2009)
Expert Opin. Ther. Targets
, vol.13
, pp. 945-956
-
-
Andreadou, I.1
Iliodromitis, E.K.2
Farmakis, D.3
Kremastinos, D.T.4
-
27
-
-
21744450416
-
Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury
-
Adlam VJ, Harrison JC, Porteous CM, James AM, Smith RA, et al. 2005. Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury. FASEB J. 19:1088-95
-
(2005)
FASEB J.
, vol.19
, pp. 1088-1095
-
-
Adlam, V.J.1
Harrison, J.C.2
Porteous, C.M.3
James, A.M.4
Smith, R.A.5
-
28
-
-
85046915361
-
N-acetylcysteine, reactive oxygen species and beyond
-
Sun SY. 2010. N-acetylcysteine, reactive oxygen species and beyond. Cancer Biol. Ther. 9:109-10
-
(2010)
Cancer Biol. Ther.
, vol.9
, pp. 109-110
-
-
Sun, S.Y.1
-
30
-
-
83355166870
-
Cyclosporine-A as a neuroprotective agent against stroke: Its translation from laboratory research to clinical application
-
Osman MM, Lulic D, Glover L, Stahl CE, Lau T, et al. 2011. Cyclosporine-A as a neuroprotective agent against stroke: its translation from laboratory research to clinical application. Neuropeptides 45:359-68
-
(2011)
Neuropeptides
, vol.45
, pp. 359-368
-
-
Osman, M.M.1
Lulic, D.2
Glover, L.3
Stahl, C.E.4
Lau, T.5
-
31
-
-
84857950728
-
Cyclosporine A-induced oxidative stress in human renal mesangial cells: A role for ERK 1/2 MAPK signaling
-
O'Connell S, Tuite N, Slattery C, Ryan MP, McMorrow T. 2012. Cyclosporine A-induced oxidative stress in human renal mesangial cells: A role for ERK 1/2 MAPK signaling. Toxicol. Sci. 126:101-13
-
(2012)
Toxicol. Sci.
, vol.126
, pp. 101-113
-
-
O'Connell, S.1
Tuite, N.2
Slattery, C.3
Ryan, M.P.4
McMorrow, T.5
-
32
-
-
84896352484
-
Aerobic interval training protects against myocardial infarction-induced oxidative injury by enhancing antioxidase system and mitochondrial biosynthesis
-
Jiang HK, Miao Y, Wang YH, Zhao M, Feng ZH, et al. 2014. Aerobic interval training protects against myocardial infarction-induced oxidative injury by enhancing antioxidase system and mitochondrial biosynthesis. Clin. Exp. Pharmacol. Physiol. 41:192-201
-
(2014)
Clin. Exp. Pharmacol. Physiol.
, vol.41
, pp. 192-201
-
-
Jiang, H.K.1
Miao, Y.2
Wang, Y.H.3
Zhao, M.4
Feng, Z.H.5
-
33
-
-
23244452012
-
Overexpression of mitochondrial transcription factor A ameliorates mitochondrial deficiencies and cardiac failure after myocardial infarction
-
Ikeuchi M, Matsusaka H, Kang D, Matsushima S, Ide T, et al. 2005. Overexpression of mitochondrial transcription factor A ameliorates mitochondrial deficiencies and cardiac failure after myocardial infarction. Circulation 112:683-90
-
(2005)
Circulation
, vol.112
, pp. 683-690
-
-
Ikeuchi, M.1
Matsusaka, H.2
Kang, D.3
Matsushima, S.4
Ide, T.5
-
34
-
-
77954829313
-
Overexpression of mitochondrial transcription factor A (TFAM) ameliorates delayed neuronal death due to transient forebrain ischemia in mice
-
Hokari M, Kuroda S, Kinugawa S, Ide T, Tsutsui H, Iwasaki Y. 2010. Overexpression of mitochondrial transcription factor A (TFAM) ameliorates delayed neuronal death due to transient forebrain ischemia in mice. Neuropathology 30:401-7
-
(2010)
Neuropathology
, vol.30
, pp. 401-407
-
-
Hokari, M.1
Kuroda, S.2
Kinugawa, S.3
Ide, T.4
Tsutsui, H.5
Iwasaki, Y.6
-
35
-
-
84904969665
-
Formoterol restores mitochondrial and renal function after ischemia-reperfusion injury
-
Jesinkey SR, Funk JA, Stallons LJ, Wills LP,Megyesi JK, et al. 2014. Formoterol restores mitochondrial and renal function after ischemia-reperfusion injury. J. Am. Soc. Nephrol. 25:1157-62
-
(2014)
J. Am. Soc. Nephrol.
, vol.25
, pp. 1157-1162
-
-
Jesinkey, S.R.1
Funk, J.A.2
Stallons, L.J.3
Wills, L.P.4
Megyesi, J.K.5
-
36
-
-
84887985169
-
CGMP-selective phosphodiesterase inhibitors stimulatemitochondrial biogenesis and promote recovery from acute kidney injury
-
Whitaker RM, Wills LP, Stallons LJ, Schnellmann RG. 2013. cGMP-selective phosphodiesterase inhibitors stimulatemitochondrial biogenesis and promote recovery from acute kidney injury. J. Pharmacol. Exp. Ther. 347:626-34
-
(2013)
J. Pharmacol. Exp. Ther.
, vol.347
, pp. 626-634
-
-
Whitaker, R.M.1
Wills, L.P.2
Stallons, L.J.3
Schnellmann, R.G.4
-
37
-
-
84905058536
-
Agonism of the 5-hydroxytryptamine 1F receptor promotes mitochondrial biogenesis and recovery from acute kidney injury
-
Garrett SM,Whitaker RM, Beeson CC, Schnellmann RG. 2014. Agonism of the 5-hydroxytryptamine 1F receptor promotes mitochondrial biogenesis and recovery from acute kidney injury. J. Pharmacol. Exp. Ther. 350:257-64
-
(2014)
J. Pharmacol. Exp. Ther.
, vol.350
, pp. 257-264
-
-
Garrett, S.M.1
Whitaker, R.M.2
Beeson, C.C.3
Schnellmann, R.G.4
-
38
-
-
84887624033
-
Induction of mitochondrial biogenesis protects against caspase-dependent and caspase-independent apoptosis in L6 myoblasts
-
Dam AD, Mitchell AS, Quadrilatero J. 2013. Induction of mitochondrial biogenesis protects against caspase-dependent and caspase-independent apoptosis in L6 myoblasts. Biochim. Biophys. Acta 1833:3426-35
-
(2013)
Biochim. Biophys. Acta
, vol.1833
, pp. 3426-3435
-
-
Dam, A.D.1
Mitchell, A.S.2
Quadrilatero, J.3
-
39
-
-
84894038619
-
Mitochondrial dysfunction in the pathophysiology of renal diseases
-
Che R, Yuan Y, Huang S, Zhang A. 2014. Mitochondrial dysfunction in the pathophysiology of renal diseases. Am. J. Physiol. Ren. Physiol. 306:F367-78
-
(2014)
Am. J. Physiol. Ren. Physiol.
, vol.306
, pp. F367-F378
-
-
Che, R.1
Yuan, Y.2
Huang, S.3
Zhang, A.4
-
40
-
-
79955664111
-
Mitochondrial protein quality control during biogenesis and aging
-
Baker BM, Haynes CM. 2011. Mitochondrial protein quality control during biogenesis and aging. Trends Biochem. Sci. 36:254-61
-
(2011)
Trends Biochem. Sci.
, vol.36
, pp. 254-261
-
-
Baker, B.M.1
Haynes, C.M.2
-
41
-
-
84897390686
-
Mitochondrial protein quality control in health and disease
-
BakerMJ, Palmer CS, Stojanovski D. 2014. Mitochondrial protein quality control in health and disease. Br. J. Pharmacol. 171:1870-89
-
(2014)
Br. J. Pharmacol.
, vol.171
, pp. 1870-1889
-
-
Baker, M.J.1
Palmer, C.S.2
Stojanovski, D.3
-
42
-
-
37049004489
-
Mitochondria in the aetiology and pathogenesis of Parkinson's disease
-
Schapira AH. 2008. Mitochondria in the aetiology and pathogenesis of Parkinson's disease. Lancet Neurol. 7:97-109
-
(2008)
Lancet Neurol.
, vol.7
, pp. 97-109
-
-
Schapira, A.H.1
-
43
-
-
84873476695
-
Animal models of Parkinson's disease: Limits and relevance to neuroprotection studies
-
Bezard E, Yue Z, Kirik D, Spillantini MG. 2013. Animal models of Parkinson's disease: limits and relevance to neuroprotection studies. Mov. Disord. 28:61-70
-
(2013)
Mov. Disord.
, vol.28
, pp. 61-70
-
-
Bezard, E.1
Yue, Z.2
Kirik, D.3
Spillantini, M.G.4
-
44
-
-
0033759168
-
The roles of dopamine oxidative stress and dopamine receptor signaling in aging and age-related neurodegeneration
-
Luo Y, Roth GS. 2000. The roles of dopamine oxidative stress and dopamine receptor signaling in aging and age-related neurodegeneration. Antioxid. Redox Signal. 2:449-60
-
(2000)
Antioxid. Redox Signal.
, vol.2
, pp. 449-460
-
-
Luo, Y.1
Roth, G.S.2
-
45
-
-
77958072667
-
PGC-1, a potential therapeutic target for early intervention in Parkinson's disease
-
Zheng B, Liao Z, Locascio JJ, Lesniak KA, Roderick SS, et al. 2010. PGC-1, a potential therapeutic target for early intervention in Parkinson's disease. Sci. Transl. Med. 2:52ra73
-
(2010)
Sci. Transl. Med.
, vol.2
, pp. 52ra73
-
-
Zheng, B.1
Liao, Z.2
Locascio, J.J.3
Lesniak, K.A.4
Roderick, S.S.5
-
46
-
-
84908647976
-
Promise of neurorestoration and mitochondrial biogenesis in Parkinson's disease with multi target drugs: An alternative to stem cell therapy
-
Youdim MB, Oh YJ. 2013. Promise of neurorestoration and mitochondrial biogenesis in Parkinson's disease with multi target drugs: An alternative to stem cell therapy. Exp. Neurobiol. 22:167-72
-
(2013)
Exp. Neurobiol.
, vol.22
, pp. 167-172
-
-
Youdim, M.B.1
Oh, Y.J.2
-
47
-
-
79957960940
-
Metabolic control ofmitochondrial biogenesis through the PGC-1 family regulatory network
-
Scarpulla RC. 2011. Metabolic control ofmitochondrial biogenesis through the PGC-1 family regulatory network. Biochim. Biophys. Acta 1813:1269-78
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 1269-1278
-
-
Scarpulla, R.C.1
-
48
-
-
84939883815
-
PPAR and PGC-1 as therapeutic targets in Parkinson's
-
Corona JC, Duchen MR. 2015. PPAR and PGC-1 as therapeutic targets in Parkinson's. Neurochem. Res. 40:308-16
-
(2015)
Neurochem. Res.
, vol.40
, pp. 308-316
-
-
Corona, J.C.1
Duchen, M.R.2
-
49
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, et al. 2006. Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127:397-408
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
-
50
-
-
84890263516
-
The protective role of AMP-activated protein kinase in alpha-synuclein neurotoxicity in vitro
-
DulovicM, Jovanovic M, XilouriM, Stefanis L, Harhaji-Trajkovic L, et al. 2014. The protective role of AMP-activated protein kinase in alpha-synuclein neurotoxicity in vitro. Neurobiol. Dis. 63:1-11
-
(2014)
Neurobiol. Dis.
, vol.63
, pp. 1-11
-
-
Dulovic, M.1
Jovanovic, M.2
Xilouri, M.3
Stefanis, L.4
Harhaji-Trajkovic, L.5
-
51
-
-
84895555916
-
The role of mitochondria in the aetiology of insulin resistance and type 2 diabetes
-
Martin SD, McGee SL. 2014. The role of mitochondria in the aetiology of insulin resistance and type 2 diabetes. Biochim. Biophys. Acta 1840:1303-12
-
(2014)
Biochim. Biophys. Acta
, vol.1840
, pp. 1303-1312
-
-
Martin, S.D.1
McGee, S.L.2
-
52
-
-
0038054341
-
PGC-1-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, et al. 2003. PGC-1-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat. Genet. 34:267-73
-
(2003)
Nat. Genet.
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
Subramanian, A.4
Sihag, S.5
-
53
-
-
84858152480
-
Oxidative stress, glutathione status, sirtuin and cellular stress response in type 2 diabetes
-
Calabrese V, Cornelius C, Leso V, Trovato-Salinaro A, Ventimiglia B, et al. 2012. Oxidative stress, glutathione status, sirtuin and cellular stress response in type 2 diabetes. Biochim. Biophys. Acta 1822:729-36
-
(2012)
Biochim. Biophys. Acta
, vol.1822
, pp. 729-736
-
-
Calabrese, V.1
Cornelius, C.2
Leso, V.3
Trovato-Salinaro, A.4
Ventimiglia, B.5
-
54
-
-
84901913666
-
Opposing effects of glucose on stroke and reperfusion injury: Acidosis, oxidative stress, and energy metabolism
-
Robbins NM, Swanson RA. 2014. Opposing effects of glucose on stroke and reperfusion injury: Acidosis, oxidative stress, and energy metabolism. Stroke 45:1881-86
-
(2014)
Stroke
, vol.45
, pp. 1881-1886
-
-
Robbins, N.M.1
Swanson, R.A.2
-
55
-
-
84857662455
-
Acute hyperglycemia in patients with acute myocardial infarction
-
Ishihara M. 2012. Acute hyperglycemia in patients with acute myocardial infarction. Circ. J. 76:563-71
-
(2012)
Circ. J.
, vol.76
, pp. 563-571
-
-
Ishihara, M.1
-
58
-
-
33644749330
-
Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells
-
Kukidome D, Nishikawa T, Sonoda K, Imoto K, Fujisawa K, et al. 2006. Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells. Diabetes 55:120-27
-
(2006)
Diabetes
, vol.55
, pp. 120-127
-
-
Kukidome, D.1
Nishikawa, T.2
Sonoda, K.3
Imoto, K.4
Fujisawa, K.5
-
59
-
-
80055050942
-
Screening for active small molecules inmitochondrial complex i deficient patient's fibroblasts, reveals AICAR as themost beneficial compound
-
Golubitzky A, Dan P, Weissman S, Link G, Wikstrom JD, Saada A. 2011. Screening for active small molecules inmitochondrial complex I deficient patient's fibroblasts, reveals AICAR as themost beneficial compound. PLOS ONE 6:e26883
-
(2011)
PLOS ONE
, vol.6
, pp. e26883
-
-
Golubitzky, A.1
Dan, P.2
Weissman, S.3
Link, G.4
Wikstrom, J.D.5
Saada, A.6
-
60
-
-
84897418338
-
Turn up the power-pharmacological activation of mitochondrial biogenesis in mouse models
-
Komen JC, Thorburn DR. 2014. Turn up the power-pharmacological activation of mitochondrial biogenesis in mouse models. Br. J. Pharmacol. 171:1818-36
-
(2014)
Br. J. Pharmacol.
, vol.171
, pp. 1818-1836
-
-
Komen, J.C.1
Thorburn, D.R.2
-
61
-
-
67349276169
-
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
-
Canto C, Gerhart-Hines Z, Feige JN, Lagouge M, Noriega L, et al. 2009. AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature 458:1056-60
-
(2009)
Nature
, vol.458
, pp. 1056-1060
-
-
Canto, C.1
Gerhart-Hines, Z.2
Feige, J.N.3
Lagouge, M.4
Noriega, L.5
-
62
-
-
84887466140
-
AMPKdysregulation promotes diabetes-related reduction of superoxide and mitochondrial function
-
Dugan LL, YouYH, Ali SS, Diamond-Stanic M, Miyamoto S, et al. 2013. AMPKdysregulation promotes diabetes-related reduction of superoxide and mitochondrial function. J. Clin. Investig. 123:4888-99
-
(2013)
J. Clin. Investig.
, vol.123
, pp. 4888-4899
-
-
Dugan, L.L.1
You, Y.H.2
Ali, S.S.3
Diamond-Stanic, M.4
Miyamoto, S.5
-
63
-
-
67650091375
-
Resveratrol induces mitochondrial biogenesis in endothelial cells
-
Csiszar A, Labinskyy N, Pinto JT, Ballabh P, Zhang H, et al. 2009. Resveratrol induces mitochondrial biogenesis in endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 297:H13-20
-
(2009)
Am. J. Physiol. Heart Circ. Physiol.
, vol.297
, pp. H13-20
-
-
Csiszar, A.1
Labinskyy, N.2
Pinto, J.T.3
Ballabh, P.4
Zhang, H.5
-
64
-
-
84874925761
-
Sirtuin 1-mediated effects of exercise and resveratrol on mitochondrial biogenesis
-
Menzies KJ, Singh K, Saleem A, Hood DA. 2013. Sirtuin 1-mediated effects of exercise and resveratrol on mitochondrial biogenesis. J. Biol. Chem. 288:6968-79
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 6968-6979
-
-
Menzies, K.J.1
Singh, K.2
Saleem, A.3
Hood, D.A.4
-
65
-
-
84921927792
-
Resveratrol preserves mitochondrial function, stimulates mitochondrial biogenesis, and attenuates oxidative stress in regulatory T cells of mice fed a high-fat diet
-
WangB, Sun J,MaY,WuG,Tian Y, et al. 2014. Resveratrol preserves mitochondrial function, stimulates mitochondrial biogenesis, and attenuates oxidative stress in regulatory T cells of mice fed a high-fat diet. J. Food Sci. 79:H1823-31
-
(2014)
J. Food Sci.
, vol.79
, pp. H1823-H1831
-
-
Wang, B.1
Sun, J.2
Ma, Y.3
Wu, G.4
Tian, Y.5
-
66
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1
-
Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, et al. 2006. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1. Cell 127:1109-22
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
-
67
-
-
77951049870
-
SRT1720 induces mitochondrial biogenesis and rescues mitochondrial function after oxidant injury in renal proximal tubule cells
-
Funk JA, Odejinmi S, Schnellmann RG. 2010. SRT1720 induces mitochondrial biogenesis and rescues mitochondrial function after oxidant injury in renal proximal tubule cells. J. Pharmacol. Exp. Ther. 333:593-601
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.333
, pp. 593-601
-
-
Funk, J.A.1
Odejinmi, S.2
Schnellmann, R.G.3
-
68
-
-
84859909860
-
SRT1720 improves survival and healthspan of obese mice
-
Minor RK, Baur JA, Gomes AP, Ward TM, Csiszar A, et al. 2011. SRT1720 improves survival and healthspan of obese mice. Sci. Rep. 1:70
-
(2011)
Sci. Rep.
, vol.1
, pp. 70
-
-
Minor, R.K.1
Baur, J.A.2
Gomes, A.P.3
Ward, T.M.4
Csiszar, A.5
-
69
-
-
84888203219
-
Accelerated recovery of renal mitochondrial and tubule homeostasis with SIRT1/PGC-1 activation following ischemia-reperfusion injury
-
Funk JA, Schnellmann RG. 2013. Accelerated recovery of renal mitochondrial and tubule homeostasis with SIRT1/PGC-1 activation following ischemia-reperfusion injury. Toxicol. Appl. Pharmacol. 273:345-54
-
(2013)
Toxicol. Appl. Pharmacol.
, vol.273
, pp. 345-354
-
-
Funk, J.A.1
Schnellmann, R.G.2
-
70
-
-
84862499070
-
The2-adrenoceptor agonist formoterol stimulates mitochondrial biogenesis
-
Wills LP, Trager RE, Beeson GC, Lindsey CC, Peterson YK, et al. 2012. The2-adrenoceptor agonist formoterol stimulates mitochondrial biogenesis. J. Pharmacol. Exp. Ther. 342:106-18
-
(2012)
J. Pharmacol. Exp. Ther.
, vol.342
, pp. 106-118
-
-
Wills, L.P.1
Trager, R.E.2
Beeson, G.C.3
Lindsey, C.C.4
Peterson, Y.K.5
-
71
-
-
76749130118
-
5-Hydroxytryptamine receptor stimulation of mitochondrial biogenesis
-
Rasbach KA, Funk JA, Jayavelu T, Green PT, Schnellmann RG. 2010. 5-Hydroxytryptamine receptor stimulation of mitochondrial biogenesis. J. Pharmacol. Exp. Ther. 332:632-39
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.332
, pp. 632-639
-
-
Rasbach, K.A.1
Funk, J.A.2
Jayavelu, T.3
Green, P.T.4
Schnellmann, R.G.5
-
72
-
-
50949092455
-
Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through endothelial nitric oxide synthase expression in white adipocytes
-
Tedesco L, Valerio A, Cervino C, Cardile A, Pagano C, et al. 2008. Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through endothelial nitric oxide synthase expression in white adipocytes. Diabetes 57:2028-36
-
(2008)
Diabetes
, vol.57
, pp. 2028-2036
-
-
Tedesco, L.1
Valerio, A.2
Cervino, C.3
Cardile, A.4
Pagano, C.5
-
73
-
-
84861746412
-
Use of clinically available PPAR agonists for heart failure; Do the risks outweigh the potential benefits
-
Sarma S. 2012. Use of clinically available PPAR agonists for heart failure; do the risks outweigh the potential benefits? Curr. Mol. Pharmacol. 5:255-63
-
(2012)
Curr. Mol. Pharmacol.
, vol.5
, pp. 255-263
-
-
Sarma, S.1
-
74
-
-
84655176686
-
Enhancing the metabolic substrate: PPAR-agonists in heart failure
-
Sarma S, Ardehali H, Gheorghiade M. 2012. Enhancing the metabolic substrate: PPAR-agonists in heart failure. Heart Fail. Rev. 17:35-43
-
(2012)
Heart Fail. Rev.
, vol.17
, pp. 35-43
-
-
Sarma, S.1
Ardehali, H.2
Gheorghiade, M.3
-
75
-
-
84859801219
-
Role of the PPAR-agonist fenofibrate in severe pediatric burn
-
Elijah IE, Borsheim E, Maybauer DM, Finnerty CC, Herndon DN, Maybauer MO. 2012. Role of the PPAR-agonist fenofibrate in severe pediatric burn. Burns 38:481-86
-
(2012)
Burns
, vol.38
, pp. 481-486
-
-
Elijah, I.E.1
Borsheim, E.2
Maybauer, D.M.3
Finnerty, C.C.4
Herndon, D.N.5
Maybauer, M.O.6
-
76
-
-
84894825487
-
Therapeutic effects of fenofibrate on diabetic peripheral neuropathy by improving endothelial and neural survival in db/db mice
-
Cho YR, Lim JH, Kim MY, Kim TW, Hong BY, et al. 2014. Therapeutic effects of fenofibrate on diabetic peripheral neuropathy by improving endothelial and neural survival in db/db mice. PLOS ONE 9:e83204
-
(2014)
PLOS ONE
, vol.9
, pp. e83204
-
-
Cho, Y.R.1
Lim, J.H.2
Kim, M.Y.3
Kim, T.W.4
Hong, B.Y.5
-
77
-
-
84875297293
-
Peroxisome proliferator activated receptor ligands as anticancer drugs targeting mitochondrial metabolism
-
Grabacka M, Pierzchalska M, Reiss K. 2013. Peroxisome proliferator activated receptor ligands as anticancer drugs targeting mitochondrial metabolism. Curr. Pharm. Biotechnol. 14:342-56
-
(2013)
Curr. Pharm. Biotechnol.
, vol.14
, pp. 342-356
-
-
Grabacka, M.1
Pierzchalska, M.2
Reiss, K.3
-
78
-
-
17844385363
-
Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue in vivo
-
Bogacka I, Xie H, Bray GA, Smith SR. 2005. Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue in vivo. Diabetes 54:1392-99
-
(2005)
Diabetes
, vol.54
, pp. 1392-1399
-
-
Bogacka, I.1
Xie, H.2
Bray, G.A.3
Smith, S.R.4
-
79
-
-
80455174540
-
Rosiglitazone-induced mitochondrial biogenesis in white adipose tissue is independent of peroxisome proliferator-activated receptor-coactivator-1
-
Pardo R, Enguix N, Lasheras J, Feliu JE, Kralli A, Villena JA. 2011. Rosiglitazone-induced mitochondrial biogenesis in white adipose tissue is independent of peroxisome proliferator-activated receptor-coactivator-1. PLOS ONE 6:e26989
-
(2011)
PLOS ONE
, vol.6
, pp. e26989
-
-
Pardo, R.1
Enguix, N.2
Lasheras, J.3
Feliu, J.E.4
Kralli, A.5
Villena, J.A.6
-
80
-
-
67650547953
-
PPAR agonism activates fatty acid oxidation via PGC-1 but does not increase mitochondrial gene expression and function
-
Kleiner S, Nguyen-Tran V, Bare O, Huang X, Spiegelman B, Wu Z. 2009. PPAR agonism activates fatty acid oxidation via PGC-1 but does not increase mitochondrial gene expression and function. J. Biol. Chem. 284:18624-33
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 18624-18633
-
-
Kleiner, S.1
Nguyen-Tran, V.2
Bare, O.3
Huang, X.4
Spiegelman, B.5
Wu, Z.6
-
81
-
-
0036142565
-
Glucocorticoid hormone stimulates mitochondrial biogenesis specifically in skeletal muscle
-
Weber K, Bruck P, Mikes Z, Kupper JH, Klingenspor M, Wiesner RJ. 2002. Glucocorticoid hormone stimulates mitochondrial biogenesis specifically in skeletal muscle. Endocrinology 143:177-84
-
(2002)
Endocrinology
, vol.143
, pp. 177-184
-
-
Weber, K.1
Bruck, P.2
Mikes, Z.3
Kupper, J.H.4
Klingenspor, M.5
Wiesner, R.J.6
-
82
-
-
79956219272
-
Dexamethasone decreases cholestatic liver injury via inhibition of intrinsic pathway with simultaneous enhancement of mitochondrial biogenesis
-
TiaoMM,LinTK, Chen JB,LiouCW,WangPW,et al. 2011. Dexamethasone decreases cholestatic liver injury via inhibition of intrinsic pathway with simultaneous enhancement of mitochondrial biogenesis. Steroids 76:660-66
-
(2011)
Steroids
, vol.76
, pp. 660-666
-
-
Tiao, M.M.1
Lin, T.K.2
Chen, J.B.3
Liou, C.W.4
Wang, P.W.5
-
83
-
-
84856855686
-
Effects of type 5-phosphodiesterase inhibition on energy metabolism and mitochondrial biogenesis in human adipose tissue ex vivo
-
De Toni L, Strapazzon G, Gianesello L, Caretta N, Pilon C, et al. 2011. Effects of type 5-phosphodiesterase inhibition on energy metabolism and mitochondrial biogenesis in human adipose tissue ex vivo. J. Endocrinol. Investig. 34:738-41
-
(2011)
J. Endocrinol. Investig.
, vol.34
, pp. 738-741
-
-
De Toni, L.1
Strapazzon, G.2
Gianesello, L.3
Caretta, N.4
Pilon, C.5
-
84
-
-
9344220484
-
Mitochondrial biogenesis byNOyields functionally active mitochondria in mammals
-
Nisoli E, Falcone S, Tonello C, Cozzi V, Palomba L, et al. 2004. Mitochondrial biogenesis byNOyields functionally active mitochondria in mammals. PNAS 101:16507-12
-
(2004)
PNAS
, vol.101
, pp. 16507-16512
-
-
Nisoli, E.1
Falcone, S.2
Tonello, C.3
Cozzi, V.4
Palomba, L.5
-
85
-
-
33749442351
-
TNF-downregulateseNOSexpression and mitochondrial biogenesis in fat and muscle of obese rodents
-
ValerioA, Cardile A, Cozzi V, Bracale R, Tedesco L, et al. 2006. TNF-downregulateseNOSexpression and mitochondrial biogenesis in fat and muscle of obese rodents. J. Clin. Investig. 116:2791-98
-
(2006)
J. Clin. Investig.
, vol.116
, pp. 2791-2798
-
-
Valerio, A.1
Cardile, A.2
Cozzi, V.3
Bracale, R.4
Tedesco, L.5
-
86
-
-
84904963071
-
Exercise training induces mitochondrial biogenesis and glucose uptake in subcutaneous adipose tissue through eNOS-dependent mechanisms
-
Trevellin E, Scorzeto M, Olivieri M, Granzotto M, Valerio A, et al. 2014. Exercise training induces mitochondrial biogenesis and glucose uptake in subcutaneous adipose tissue through eNOS-dependent mechanisms. Diabetes 63:2800-11
-
(2014)
Diabetes
, vol.63
, pp. 2800-2811
-
-
Trevellin, E.1
Scorzeto, M.2
Olivieri, M.3
Granzotto, M.4
Valerio, A.5
-
87
-
-
84899551597
-
Exercise training boosts eNOSdependent mitochondrial biogenesis in mouse heart: Role in adaptation of glucose metabolism
-
Vettor R, Valerio A, Ragni M, Trevellin E, Granzotto M, et al. 2014. Exercise training boosts eNOSdependent mitochondrial biogenesis in mouse heart: role in adaptation of glucose metabolism. Am. J. Physiol. Endocrinol. Metab. 306:E519-28
-
(2014)
Am. J. Physiol. Endocrinol. Metab.
, vol.306
, pp. E519-E528
-
-
Vettor, R.1
Valerio, A.2
Ragni, M.3
Trevellin, E.4
Granzotto, M.5
-
88
-
-
84858266346
-
Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: Role of hydrogen sulfide
-
Salloum FN, Das A, Samidurai A, Hoke NN, Chau VQ, et al. 2012. Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: role of hydrogen sulfide. Am. J. Physiol. Heart Circ. Physiol. 302:H1347-54
-
(2012)
Am. J. Physiol. Heart Circ. Physiol.
, vol.302
, pp. H1347-H1354
-
-
Salloum, F.N.1
Das, A.2
Samidurai, A.3
Hoke, N.N.4
Chau, V.Q.5
-
89
-
-
84883144236
-
The soluble guanylate cyclase activator BAY 58-2667 protects against morbidity and mortality in endotoxic shock by recoupling organ systems
-
Vandendriessche B, Rogge E, Goossens V, Vandenabeele P, Stasch JP, et al. 2013. The soluble guanylate cyclase activator BAY 58-2667 protects against morbidity and mortality in endotoxic shock by recoupling organ systems. PLOS ONE 8:e72155
-
(2013)
PLOS ONE
, vol.8
, pp. e72155
-
-
Vandendriessche, B.1
Rogge, E.2
Goossens, V.3
Vandenabeele, P.4
Stasch, J.P.5
-
90
-
-
73249127018
-
Natriuretic peptides/cGMP/cGMP-dependent protein kinase cascades promotemuscle mitochondrial biogenesis and prevent obesity
-
Miyashita K, Itoh H, Tsujimoto H, Tamura N, Fukunaga Y, et al. 2009. Natriuretic peptides/cGMP/cGMP-dependent protein kinase cascades promotemuscle mitochondrial biogenesis and prevent obesity. Diabetes 58:2880-92
-
(2009)
Diabetes
, vol.58
, pp. 2880-2892
-
-
Miyashita, K.1
Itoh, H.2
Tsujimoto, H.3
Tamura, N.4
Fukunaga, Y.5
-
91
-
-
84870492539
-
Natriuretic peptides enhance the oxidative capacity of human skeletal muscle
-
Engeli S, Birkenfeld AL, Badin PM, Bourlier V, Louche K, et al. 2012. Natriuretic peptides enhance the oxidative capacity of human skeletal muscle. J. Clin. Investig. 122:4675-79
-
(2012)
J. Clin. Investig.
, vol.122
, pp. 4675-4679
-
-
Engeli, S.1
Birkenfeld, A.L.2
Badin, P.M.3
Bourlier, V.4
Louche, K.5
-
92
-
-
84863229962
-
Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes
-
Bordicchia M, Liu D, Amri EZ, Ailhaud G, Dessi-Fulgheri P, et al. 2012. Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes. J. Clin. Investig. 122:1022-36
-
(2012)
J. Clin. Investig.
, vol.122
, pp. 1022-1036
-
-
Bordicchia, M.1
Liu, D.2
Amri, E.Z.3
Ailhaud, G.4
Dessi-Fulgheri, P.5
-
93
-
-
84878665072
-
Green tea polyphenols stimulate mitochondrial biogenesis and improve renal function after chronic cyclosporin a treatment in rats
-
Rehman H, Krishnasamy Y, Haque K, Thurman RG, Lemasters JJ, et al. 2014. Green tea polyphenols stimulate mitochondrial biogenesis and improve renal function after chronic cyclosporin a treatment in rats. PLOS ONE 8:e65029
-
(2014)
PLOS ONE
, vol.8
, pp. e65029
-
-
Rehman, H.1
Krishnasamy, Y.2
Haque, K.3
Thurman, R.G.4
Lemasters, J.J.5
-
94
-
-
79551501886
-
Lipoamide or lipoic acid stimulates mitochondrial biogenesis in 3T3-L1 adipocytes via the endothelial NO synthase-cGMP-protein kinase G signalling pathway
-
ShenW,Hao J, Feng Z, Tian C, Chen W, et al. 2011. Lipoamide or lipoic acid stimulates mitochondrial biogenesis in 3T3-L1 adipocytes via the endothelial NO synthase-cGMP-protein kinase G signalling pathway. Br. J. Pharmacol. 162:1213-24
-
(2011)
Br. J. Pharmacol.
, vol.162
, pp. 1213-1224
-
-
Shen, W.1
Hao, J.2
Feng, Z.3
Tian, C.4
Chen, W.5
-
97
-
-
84888875316
-
Quercetin induces mitochondrial biogenesis through activation of HO-1 in HepG2 cells
-
Rayamajhi N, Kim SK,GoH, Joe Y, Callaway Z, et al. 2013. Quercetin induces mitochondrial biogenesis through activation of HO-1 in HepG2 cells. Oxid. Med. Cell Longev. 2013:154279
-
(2013)
Oxid. Med. Cell Longev.
, vol.2013
, pp. 154279
-
-
Rayamajhi, N.1
Kim, S.K.2
Go, H.3
Joe, Y.4
Callaway, Z.5
-
98
-
-
78650034461
-
Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin
-
Thomas RR, Khan SM, Portell FR, Smigrodzki RM, Bennett JP Jr. 2011. Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin. Mitochondrion 11:108-18
-
(2011)
Mitochondrion
, vol.11
, pp. 108-118
-
-
Thomas, R.R.1
Khan, S.M.2
Portell, F.R.3
Smigrodzki, R.M.4
Bennett, J.P.5
-
99
-
-
84872577068
-
RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice
-
Thomas RR, Khan SM, Smigrodzki RM, Onyango IG, Dennis J, et al. 2012. RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice. Aging 4:620-35
-
(2012)
Aging
, vol.4
, pp. 620-635
-
-
Thomas, R.R.1
Khan, S.M.2
Smigrodzki, R.M.3
Onyango, I.G.4
Dennis, J.5
-
100
-
-
84861752822
-
Mitochondrial gene therapy improves respiration, biogenesis, and transcription in G11778A Leber's hereditary optic neuropathy and T8993G Leigh's syndrome cells
-
Iyer S, Bergquist K, Young K, Gnaiger E, Rao RR, Bennett JP Jr. 2012. Mitochondrial gene therapy improves respiration, biogenesis, and transcription in G11778A Leber's hereditary optic neuropathy and T8993G Leigh's syndrome cells. Hum. Gene Ther. 23:647-57
-
(2012)
Hum. Gene Ther.
, vol.23
, pp. 647-657
-
-
Iyer, S.1
Bergquist, K.2
Young, K.3
Gnaiger, E.4
Rao, R.R.5
Bennett, J.P.6
-
101
-
-
80053035284
-
AMP-activated protein kinase: An energy sensor that regulates all aspects of cell function
-
Hardie DG. 2011. AMP-activated protein kinase: An energy sensor that regulates all aspects of cell function. Genes Dev. 25:1895-908
-
(2011)
Genes Dev.
, vol.25
, pp. 1895-1908
-
-
Hardie, D.G.1
-
102
-
-
48449094498
-
AMPK and PPAR? Agonists are exercise mimetics
-
Narkar VA, Downes M, Yu RT, Embler E, Wang YX, et al. 2008. AMPK and PPAR? agonists are exercise mimetics. Cell 134:405-15
-
(2008)
Cell
, vol.134
, pp. 405-415
-
-
Narkar, V.A.1
Downes, M.2
Yu, R.T.3
Embler, E.4
Wang, Y.X.5
-
103
-
-
0032881635
-
Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR
-
Russell RR 3rd, Bergeron R, Shulman GI, Young LH. 1999. Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR. Am. J. Physiol. 277:H643-49
-
(1999)
Am. J. Physiol.
, vol.277
, pp. H643-H649
-
-
Russell, R.R.1
Bergeron, R.2
Shulman, G.I.3
Young, L.H.4
-
104
-
-
84863228208
-
AMPK activator AICAR ameliorates ischaemia reperfusion injury in the rat kidney
-
Lempiainen J, Finckenberg P, Levijoki J, Mervaala E. 2012. AMPK activator AICAR ameliorates ischaemia reperfusion injury in the rat kidney. Br. J. Pharmacol. 166:1905-15
-
(2012)
Br. J. Pharmacol.
, vol.166
, pp. 1905-1915
-
-
Lempiainen, J.1
Finckenberg, P.2
Levijoki, J.3
Mervaala, E.4
-
105
-
-
20144386698
-
Long-term AICAR administration and exercise prevents diabetes in ZDF rats
-
Pold R, Jensen LS, Jessen N, Buhl ES, Schmitz O, et al. 2005. Long-term AICAR administration and exercise prevents diabetes in ZDF rats. Diabetes 54:928-34
-
(2005)
Diabetes
, vol.54
, pp. 928-934
-
-
Pold, R.1
Jensen, L.S.2
Jessen, N.3
Buhl, E.S.4
Schmitz, O.5
-
106
-
-
84961291233
-
Sirtuin 3-dependent mitochondrial dynamic improvements protect against acute kidney injury
-
Morigi M, Perico L, Rota C, Longaretti L, Conti S, et al. 2015. Sirtuin 3-dependent mitochondrial dynamic improvements protect against acute kidney injury. J. Clin. Investig. 125:715-26
-
(2015)
J. Clin. Investig.
, vol.125
, pp. 715-726
-
-
Morigi, M.1
Perico, L.2
Rota, C.3
Longaretti, L.4
Conti, S.5
-
107
-
-
64549127790
-
PGC-1, SIRT1 and AMPK, an energy sensing network that controls energy expenditure
-
Canto C, Auwerx J. 2009. PGC-1, SIRT1 and AMPK, an energy sensing network that controls energy expenditure. Curr. Opin. Lipidol. 20:98-105
-
(2009)
Curr. Opin. Lipidol.
, vol.20
, pp. 98-105
-
-
Canto, C.1
Auwerx, J.2
-
108
-
-
77955088481
-
Resveratrol as a therapeutic agent for neurodegenerative diseases
-
Sun AY, Wang Q, Simonyi A, Sun GY. 2010. Resveratrol as a therapeutic agent for neurodegenerative diseases. Mol. Neurobiol. 41:375-83
-
(2010)
Mol. Neurobiol.
, vol.41
, pp. 375-383
-
-
Sun, A.Y.1
Wang, Q.2
Simonyi, A.3
Sun, G.Y.4
-
109
-
-
84897429184
-
Effect of resveratrol on mitochondrial function: Implications in parkin-associated familiar Parkinson's disease
-
Ferretta A, Gaballo A, Tanzarella P, Piccoli C, Capitanio N, et al. 2014. Effect of resveratrol on mitochondrial function: implications in parkin-associated familiar Parkinson's disease. Biochim. Biophys. Acta 1842:902-15
-
(2014)
Biochim. Biophys. Acta
, vol.1842
, pp. 902-915
-
-
Ferretta, A.1
Gaballo, A.2
Tanzarella, P.3
Piccoli, C.4
Capitanio, N.5
-
110
-
-
80053937926
-
Neuroprotective andmetabolic effects of resveratrol: Therapeutic implications for Huntington's disease and other neurodegenerative disorders
-
Pasinetti GM,Wang J,Marambaud P, Ferruzzi M, Gregor P, et al. 2011. Neuroprotective andmetabolic effects of resveratrol: Therapeutic implications for Huntington's disease and other neurodegenerative disorders. Exp. Neurol. 232:1-6
-
(2011)
Exp. Neurol.
, vol.232
, pp. 1-6
-
-
Pasinetti, G.M.1
Wang, J.2
Marambaud, P.3
Ferruzzi, M.4
Gregor, P.5
-
112
-
-
84874523611
-
Resveratrol reverses remodeling in hearts with large, old myocardial infarctions through enhanced autophagy-activating AMP kinase pathway
-
KanamoriH, TakemuraG, Goto K, Tsujimoto A, Ogino A, et al. 2013. Resveratrol reverses remodeling in hearts with large, old myocardial infarctions through enhanced autophagy-activating AMP kinase pathway. Am. J. Pathol. 182:701-13
-
(2013)
Am. J. Pathol.
, vol.182
, pp. 701-713
-
-
Kanamori, H.1
Takemura, G.2
Goto, K.3
Tsujimoto, A.4
Ogino, A.5
-
113
-
-
60949087943
-
Long-term resveratrol administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats
-
Rivera L, Moron R, Zarzuelo A, Galisteo M. 2009. Long-term resveratrol administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats. Biochem. Pharmacol. 77:1053-63
-
(2009)
Biochem. Pharmacol.
, vol.77
, pp. 1053-1063
-
-
Rivera, L.1
Moron, R.2
Zarzuelo, A.3
Galisteo, M.4
-
114
-
-
78149281050
-
Resveratrol: A relevant pharmacological approach for the treatment of metabolic syndrome
-
Beaudeux JL, Nivet-Antoine V, Giral P. 2010. Resveratrol: A relevant pharmacological approach for the treatment of metabolic syndrome? Curr. Opin. Clin. Nutr. Metab. Care 13:729-36
-
(2010)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.13
, pp. 729-736
-
-
Beaudeux, J.L.1
Nivet-Antoine, V.2
Giral, P.3
-
115
-
-
80052910300
-
Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients
-
Brasnyo P,Molnar GA, MohasM,Marko L, Laczy B, et al. 2011. Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients. Br. J. Nutr. 106:383-89
-
(2011)
Br. J. Nutr.
, vol.106
, pp. 383-389
-
-
Brasnyo, P.1
Molnar, G.A.2
Mohas, M.3
Marko, L.4
Laczy, B.5
-
116
-
-
36749087548
-
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
-
Milne JC, Lambert PD, Schenk S, Carney DP, Smith JJ, et al. 2007. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 450:712-16
-
(2007)
Nature
, vol.450
, pp. 712-716
-
-
Milne, J.C.1
Lambert, P.D.2
Schenk, S.3
Carney, D.P.4
Smith, J.J.5
-
117
-
-
33646538121
-
SIRT1 stimulation by polyphenols is affected by their stability and metabolism
-
de Boer VC, de Goffau MC, Arts IC, Hollman PC, Keijer J. 2006. SIRT1 stimulation by polyphenols is affected by their stability and metabolism. Mech. Ageing Dev. 127:618-27
-
(2006)
Mech. Ageing Dev.
, vol.127
, pp. 618-627
-
-
De Boer, V.C.1
De Goffau, M.C.2
Arts, I.C.3
Hollman, P.C.4
Keijer, J.5
-
118
-
-
84861161546
-
SIRT3 is a mitochondrial tumor suppressor: A scientific tale that connects aberrant cellular ROS, theWarburg effect, and carcinogenesis
-
Haigis MC, Deng CX, Finley LW, Kim HS, Gius D. 2012. SIRT3 is a mitochondrial tumor suppressor: A scientific tale that connects aberrant cellular ROS, theWarburg effect, and carcinogenesis. Cancer Res. 72:2468-72
-
(2012)
Cancer Res.
, vol.72
, pp. 2468-2472
-
-
Haigis, M.C.1
Deng, C.X.2
Finley, L.W.3
Kim, H.S.4
Gius, D.5
-
119
-
-
0037326196
-
Peroxisome proliferator-activated receptor-coactivator 1 (PGC-1): Transcriptional coactivator and metabolic regulator
-
Puigserver P, Spiegelman BM. 2003. Peroxisome proliferator-activated receptor-coactivator 1 (PGC-1): transcriptional coactivator and metabolic regulator. Endocr. Rev. 24:78-90
-
(2003)
Endocr. Rev.
, vol.24
, pp. 78-90
-
-
Puigserver, P.1
Spiegelman, B.M.2
-
120
-
-
84856995221
-
Clenbuterol, a2-adrenergic agonist, reciprocally alters PGC-1? and RIP140 and reduces fatty acid and pyruvate oxidation in rat skeletal muscle
-
Hoshino D, Yoshida Y, Holloway GP, Lally J, Hatta H, Bonen A. 2012. Clenbuterol, a2-adrenergic agonist, reciprocally alters PGC-1? and RIP140 and reduces fatty acid and pyruvate oxidation in rat skeletal muscle. Am. J. Physiol. Regul. Integr. Comp. Physiol. 302:R373-84
-
(2012)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.302
, pp. R373-R384
-
-
Hoshino, D.1
Yoshida, Y.2
Holloway, G.P.3
Lally, J.4
Hatta, H.5
Bonen, A.6
-
121
-
-
84883488733
-
2-adrenoceptor agonists in the regulation of mitochondrial biogenesis
-
Peterson YK, Cameron RB, Wills LP, Trager RE, Lindsey CC, et al. 2013. 2-adrenoceptor agonists in the regulation of mitochondrial biogenesis. Bioorg. Med. Chem. Lett. 23:5376-81
-
(2013)
Bioorg. Med. Chem. Lett.
, vol.23
, pp. 5376-5381
-
-
Peterson, Y.K.1
Cameron, R.B.2
Wills, L.P.3
Trager, R.E.4
Lindsey, C.C.5
-
122
-
-
26844558334
-
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
-
Nisoli E, Tonello C, Cardile A, Cozzi V, Bracale R, et al. 2005. Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science 310:314-17
-
(2005)
Science
, vol.310
, pp. 314-317
-
-
Nisoli, E.1
Tonello, C.2
Cardile, A.3
Cozzi, V.4
Bracale, R.5
-
123
-
-
0347579845
-
Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide
-
Nisoli E, ClementiE, Paolucci C, Cozzi V, Tonello C, et al. 2003. Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide. Science 299:896-99
-
(2003)
Science
, vol.299
, pp. 896-899
-
-
Nisoli, E.1
Clementi, E.2
Paolucci, C.3
Cozzi, V.4
Tonello, C.5
-
124
-
-
33746841367
-
Nitric oxide and mitochondrial biogenesis
-
Nisoli E, Carruba MO. 2006. Nitric oxide and mitochondrial biogenesis. J. Cell Sci. 119:2855-62
-
(2006)
J. Cell Sci.
, vol.119
, pp. 2855-2862
-
-
Nisoli, E.1
Carruba, M.O.2
-
125
-
-
69349091599
-
PPAR stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss
-
Miglio G, Rosa AC,Rattazzi L, CollinoM, LombardiG, Fantozzi R. 2009. PPAR-stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss. Neurochem. Int. 55:496-504
-
(2009)
Neurochem. Int.
, vol.55
, pp. 496-504
-
-
Miglio, G.1
Rosa, A.C.2
Rattazzi, L.3
Collino, M.4
Lombardi, G.5
Fantozzi, R.6
-
126
-
-
79955763790
-
Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPAR, and HO-1
-
Wu QQ, Wang Y, SenitkoM,Meyer C, Wigley WC, et al. 2011. Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPAR, and HO-1. Am. J. Physiol. Ren. Physiol. 300:F1180-92
-
(2011)
Am. J. Physiol. Ren. Physiol.
, vol.300
, pp. F1180-F1192
-
-
Wu, Q.Q.1
Wang, Y.2
Senitko, M.3
Meyer, C.4
Wigley, W.C.5
-
127
-
-
84900558337
-
Explicit role of peroxisome proliferator-activated receptor-in gallic acid-mediated protection against ischemia-reperfusion-induced acute kidney injury in rats
-
Singh JP, Singh AP, Bhatti R. 2014. Explicit role of peroxisome proliferator-activated receptor-in gallic acid-mediated protection against ischemia-reperfusion-induced acute kidney injury in rats. J. Surg. Res. 187:631-39
-
(2014)
J. Surg. Res.
, vol.187
, pp. 631-639
-
-
Singh, J.P.1
Singh, A.P.2
Bhatti, R.3
-
128
-
-
84859464827
-
Persistent disruption of mitochondrial homeostasis after acute kidney injury
-
Funk JA, Schnellmann RG. 2012. Persistent disruption of mitochondrial homeostasis after acute kidney injury. Am. J. Physiol. Ren. Physiol. 302:F853-64
-
(2012)
Am. J. Physiol. Ren. Physiol.
, vol.302
, pp. F853-F864
-
-
Funk, J.A.1
Schnellmann, R.G.2
-
129
-
-
84890230244
-
Suppressed mitochondrial biogenesis in folic acidinduced acute kidney injury and early fibrosis
-
Stallons LJ, Whitaker RM, Schnellmann RG. 2014. Suppressed mitochondrial biogenesis in folic acidinduced acute kidney injury and early fibrosis. Toxicol. Lett. 224:326-32
-
(2014)
Toxicol. Lett.
, vol.224
, pp. 326-332
-
-
Stallons, L.J.1
Whitaker, R.M.2
Schnellmann, R.G.3
-
130
-
-
84921311514
-
Suppression of mitochondrial biogenesis through toll-like receptor 4-dependent mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling in endotoxin-induced acute kidney injury
-
Smith JA, Stallons LJ, Collier JB, Chavin KD, Schnellmann RG. 2015. Suppression of mitochondrial biogenesis through toll-like receptor 4-dependent mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling in endotoxin-induced acute kidney injury. J. Pharmacol. Exp. Ther. 352:346-57
-
(2015)
J. Pharmacol. Exp. Ther.
, vol.352
, pp. 346-357
-
-
Smith, J.A.1
Stallons, L.J.2
Collier, J.B.3
Chavin, K.D.4
Schnellmann, R.G.5
-
131
-
-
34347391646
-
Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone
-
Rong JX, Qiu Y, Hansen MK, Zhu L, Zhang V, et al. 2007. Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone. Diabetes 56:1751-60
-
(2007)
Diabetes
, vol.56
, pp. 1751-1760
-
-
Rong, J.X.1
Qiu, Y.2
Hansen, M.K.3
Zhu, L.4
Zhang, V.5
-
132
-
-
84900330082
-
Mitochondrial aging and age-related dysfunction of mitochondria
-
Chistiakov DA, Sobenin IA, Revin VV, Orekhov AN, Bobryshev YV. 2014. Mitochondrial aging and age-related dysfunction of mitochondria. Biomed. Res. Int. 2014:238463
-
(2014)
Biomed. Res. Int.
, vol.2014
, pp. 238463
-
-
Chistiakov, D.A.1
Sobenin, I.A.2
Revin, V.V.3
Orekhov, A.N.4
Bobryshev, Y.V.5
-
133
-
-
84863952749
-
Age-associated declines in mitochondrial biogenesis and protein quality control factors are minimized by exercise training
-
Koltai E, Hart N, Taylor AW, Goto S, Ngo JK, et al. 2012. Age-associated declines in mitochondrial biogenesis and protein quality control factors are minimized by exercise training. Am. J. Physiol. Regul. Integr. Comp. Physiol. 303:R127-34
-
(2012)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.303
, pp. R127-R134
-
-
Koltai, E.1
Hart, N.2
Taylor, A.W.3
Goto, S.4
Ngo, J.K.5
-
134
-
-
60149110303
-
TNF-reduces PGC-1-expression through NF-B and p38MAPK leading to increased glucose oxidation in a human cardiac cell model
-
Palomer X, Alvarez-Guardia D, Rodriguez-Calvo R, Coll T, Laguna JC, et al. 2009. TNF-reduces PGC-1-expression through NF-B and p38MAPK leading to increased glucose oxidation in a human cardiac cell model. Cardiovasc. Res. 81:703-12
-
(2009)
Cardiovasc. Res.
, vol.81
, pp. 703-712
-
-
Palomer, X.1
Alvarez-Guardia, D.2
Rodriguez-Calvo, R.3
Coll, T.4
Laguna, J.C.5
-
135
-
-
79955542142
-
Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression
-
Piantadosi CA, Withers CM, Bartz RR, MacGarvey NC, Fu P, et al. 2011. Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression. J. Biol. Chem. 286:16374-85
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 16374-16385
-
-
Piantadosi, C.A.1
Withers, C.M.2
Bartz, R.R.3
MacGarvey, N.C.4
Fu, P.5
-
136
-
-
77950275298
-
Circulating mitochondrial DAMPs cause inflammatory responses to injury
-
Zhang Q, Raoof M, Chen Y, Sumi Y, Sursal T, et al. 2010. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature 464:104-7
-
(2010)
Nature
, vol.464
, pp. 104-107
-
-
Zhang, Q.1
Raoof, M.2
Chen, Y.3
Sumi, Y.4
Sursal, T.5
-
137
-
-
84869101137
-
TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis
-
Ye L, Kleiner S, Wu J, Sah R, Gupta RK, et al. 2012. TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis. Cell 151:96-110
-
(2012)
Cell
, vol.151
, pp. 96-110
-
-
Ye, L.1
Kleiner, S.2
Wu, J.3
Sah, R.4
Gupta, R.K.5
-
138
-
-
42449092519
-
Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1-and oxidative phosphorylation
-
Arany Z,Wagner BK, Ma Y, Chinsomboon J, Laznik D, Spiegelman BM. 2008. Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1-and oxidative phosphorylation. PNAS 105:4721-26
-
(2008)
PNAS
, vol.105
, pp. 4721-4726
-
-
Arany, Z.1
Wagner, B.K.2
Ma, Y.3
Chinsomboon, J.4
Laznik, D.5
Spiegelman, B.M.6
-
139
-
-
77954177589
-
A high-throughput respirometric assay for mitochondrial biogenesis and toxicity
-
Beeson CC, Beeson GC, Schnellmann RG. 2010. A high-throughput respirometric assay for mitochondrial biogenesis and toxicity. Anal. Biochem. 404:75-81
-
(2010)
Anal. Biochem.
, vol.404
, pp. 75-81
-
-
Beeson, C.C.1
Beeson, G.C.2
Schnellmann, R.G.3
-
140
-
-
84884144226
-
High-throughput respirometric assay identifies predictive toxicophore of mitochondrial injury
-
Wills LP, Beeson GC, Trager RE, Lindsey CC, Beeson CC, et al. 2013. High-throughput respirometric assay identifies predictive toxicophore of mitochondrial injury. Toxicol. Appl. Pharmacol. 272:490-502
-
(2013)
Toxicol. Appl. Pharmacol.
, vol.272
, pp. 490-502
-
-
Wills, L.P.1
Beeson, G.C.2
Trager, R.E.3
Lindsey, C.C.4
Beeson, C.C.5
-
141
-
-
77952236126
-
Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury
-
Ong SB, Subrayan S, Lim SY, YellonDM, Davidson SM,Hausenloy DJ. 2010. Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury. Circulation 121:2012-22
-
(2010)
Circulation
, vol.121
, pp. 2012-2022
-
-
Ong, S.B.1
Subrayan, S.2
Lim, S.Y.3
Yellon, D.M.4
Davidson, S.M.5
Hausenloy, D.J.6
-
142
-
-
4444270915
-
Dysregulation ofHSG triggers vascular proliferative disorders
-
Chen KH, Guo X, Ma D, Guo Y, Li Q, et al. 2004. Dysregulation ofHSG triggers vascular proliferative disorders. Nat. Cell Biol. 6:872-83
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 872-883
-
-
Chen, K.H.1
Guo, X.2
Ma, D.3
Guo, Y.4
Li, Q.5
-
143
-
-
84904755670
-
Overexpression of mitofusin 2 inhibits reactive astrogliosis proliferation in vitro
-
Liu T, Xue CC, Shi YL, Bai XJ, Li ZF, Yi CL. 2014. Overexpression of mitofusin 2 inhibits reactive astrogliosis proliferation in vitro. Neurosci. Lett. 579:24-29
-
(2014)
Neurosci. Lett.
, vol.579
, pp. 24-29
-
-
Liu, T.1
Xue, C.C.2
Shi, Y.L.3
Bai, X.J.4
Li, Z.F.5
Yi, C.L.6
-
144
-
-
0030889792
-
Protective effect of captopril on ischemic myocardium
-
YanagishitaT,TomitaM, Itoh S,Mukae S, ArataH, et al. 1997. Protective effect of captopril on ischemic myocardium. Jpn. Circ. J. 61:161-69
-
(1997)
Jpn. Circ. J.
, vol.61
, pp. 161-169
-
-
Yanagishita, T.1
Tomita, M.2
Itoh, S.3
Mukae, S.4
Arata, H.5
-
145
-
-
84881232428
-
Randomized-controlled trial of minocycline for spinal cord injury shows promise
-
Monaco EA 3rd, Weiner GM, Friedlander RM. 2013. Randomized-controlled trial of minocycline for spinal cord injury shows promise. Neurosurgery 72:N17-19
-
(2013)
Neurosurgery
, vol.72
, pp. N17-19
-
-
Monaco, E.A.1
Weiner, G.M.2
Friedlander, R.M.3
|