CGMP-selective phosphodiesterase inhibitors stimulate mitochondrial biogenesis and promote recovery from acute kidney injury

Journal of Pharmacology and Experimental Therapeutics

Volumn 347, Issue 3, 2013, Pages 626-634

  Whitaker, Ryan M ^b   Wills, Lauren P ^b   Stallons, L Jay ^b   Schnellmann, Rick G ^a,b  

^a RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO CYCLIC AMP; 8 BROMO CYCLIC GMP; CILOSTAMIDE; CYCLIC GMP; FOLIC ACID; MITOCHONDRIAL DNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHODIESTERASE III; PHOSPHODIESTERASE III INHIBITOR; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; PHOSPHODIESTERASE V; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL; TREQUINSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE DOSAGE; GENE EXPRESSION; IN VIVO STUDY; KIDNEY CORTEX; KIDNEY INJURY; KIDNEY TUBULE CELL; MITOCHONDRIAL BIOGENESIS; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL GENE; MITOCHONDRION; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RABBIT;

3',5'-CYCLIC-AMP PHOSPHODIESTERASES; ACUTE KIDNEY INJURY; ADENOSINE TRIPHOSPHATE; ANIMALS; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLIC ACID; GENE EXPRESSION; HEMATINICS; KIDNEY CORTEX; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; OXYGEN CONSUMPTION; PHOSPHODIESTERASE 3 INHIBITORS; PHOSPHODIESTERASE 4 INHIBITORS; PHOSPHODIESTERASE 5 INHIBITORS; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; PURINES; RABBITS; REAL-TIME POLYMERASE CHAIN REACTION; SULFONES; UNCOUPLING AGENTS;

EID: 84887985169     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.113.208017     Document Type: Article

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