Lipoamide or lipoic acid stimulates mitochondrial biogenesis in 3T3-L1 adipocytes via the endothelial NO synthase-cGMP-protein kinase G signalling pathway

British Journal of Pharmacology

Volumn 162, Issue 5, 2011, Pages 1213-1224

  Shen, Weili ^a   Hao, Jiejie ^b   Feng, Zhihui ^c   Tian, Chuan ^c   Chen, Weijun ^d   Packer, Lester ^e   Shi, Xianglin ^f   Zang, Weijin ^g   Liu, Jiankang ^d,h  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b OCEAN UNIVERSITY OF CHINA   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d INSTITUTE OF TROPICAL BIOSCIENCE AND BIOTECHNOLOGY   (China)

^e UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^f UNIVERSITY OF KENTUCKY   (United States)

^g MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^h XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

lipoamide; lipoic acid; mitochondria; mitochondrial transcription factor A (TFAM); nuclear respiratory factor 1 (NRF1); peroxisome proliferator activated receptor co activator 1 (PGC 1 )

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; AMIDE; CARNITINE PALMITOYLTRANSFERASE I; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; KT 5823; MESSENGER RNA; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; NUCLEAR RESPIRATORY FACTOR 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SMALL INTERFERING RNA; THIOCTAMIDE; THIOCTIC ACID; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; BIOGENESIS; CELL VOLUME; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; GENE DOSAGE; GENE EXPRESSION; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; BASE SEQUENCE; CARNITINE O-PALMITOYLTRANSFERASE; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; DNA PRIMERS; DNA, MITOCHONDRIAL; HYPOGLYCEMIC AGENTS; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NITRIC OXIDE SYNTHASE TYPE III; OXYGEN CONSUMPTION; PPAR ALPHA; PPAR GAMMA; RNA, MESSENGER; SIGNAL TRANSDUCTION; THIOCTIC ACID;

EID: 79551501886     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.01134.x     Document Type: Article

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