Mitochondrial gene therapy improves respiration, biogenesis, and transcription in G11778A leber's hereditary optic neuropathy and T8993G leigh's syndrome cells

Human Gene Therapy

Volumn 23, Issue 6, 2012, Pages 647-657

  Iyer, Shilpa ^a   Bergquist, Kristen ^b   Young, Kisha ^b   Gnaiger, Erich ^c   Rao, Raj R ^d   Bennett, James P ^b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^d Virginia Commonwealth University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; TRANSCRIPTION FACTOR NRF1;

ARTICLE; BIOGENESIS; CELL BASED GENE THERAPY; GENE DOSAGE; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; LEBER HEREDITARY OPTIC NEUROPATHY; LEIGH DISEASE; MITOCHONDRIAL DNA REPLICATION; MITOCHONDRIAL GENE; MITOCHONDRIAL RESPIRATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; TRANSCRIPTION REGULATION; TRANSLATION INITIATION;

EID: 84861752822     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2011.177     Document Type: Article

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