-
1
-
-
84901310586
-
Mechanisms and functions of inflammasomes
-
LamkanfiM, Dixit VM. Mechanisms and functions of inflammasomes. Cell (2014) 157(5):1013-22. doi: 10.1016/j.cell.2014.04.007.
-
(2014)
Cell
, vol.157
, Issue.5
, pp. 1013-1022
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
2
-
-
79956299492
-
Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1beta activation and severe autoinflammation in mice
-
Chae JJ, Cho YH, Lee GS, Cheng J, Liu PP, Feigenbaum L, et al. Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1beta activation and severe autoinflammation in mice. Immunity (2011) 34(5):755-68. doi:10.1016/j.immuni.2011.02.020.
-
(2011)
Immunity
, vol.34
, Issue.5
, pp. 755-768
-
-
Chae, J.J.1
Cho, Y.H.2
Lee, G.S.3
Cheng, J.4
Liu, P.P.5
Feigenbaum, L.6
-
3
-
-
34547138176
-
The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing
-
Papin S, Cuenin S, Agostini L, Martinon F, Werner S, Beer HD, et al. The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing. Cell Death Differ (2007) 14(8):1457-66. doi:10.1038/sj.cdd.4402142.
-
(2007)
Cell Death Differ
, vol.14
, Issue.8
, pp. 1457-1466
-
-
Papin, S.1
Cuenin, S.2
Agostini, L.3
Martinon, F.4
Werner, S.5
Beer, H.D.6
-
4
-
-
84927724336
-
Initiation and perpetuation of NLRP3 inflammasome activation and assembly
-
Elliott EI, Sutterwala FS. Initiation and perpetuation of NLRP3 inflammasome activation and assembly. Immunol Rev (2015) 265(1):35-52. doi:10.1111/imr.12286.
-
(2015)
Immunol Rev
, vol.265
, Issue.1
, pp. 35-52
-
-
Elliott, E.I.1
Sutterwala, F.S.2
-
5
-
-
84905660109
-
Emerging concepts about NAIP/NLRC4 inflammasomes
-
Lage SL, Longo C, Branco LM, da Costa TB, Buzzo Cde L, Bortoluci KR. Emerging concepts about NAIP/NLRC4 inflammasomes. Front Immunol (2014) 5:309. doi:10.3389/fimmu.2014.00309.
-
(2014)
Front Immunol
, vol.5
, pp. 309
-
-
Lage, S.L.1
Longo, C.2
Branco, L.M.3
da Costa, T.B.4
Buzzo Cde, L.5
Bortoluci, K.R.6
-
6
-
-
84921498910
-
The NAIP/NLRC4 inflammasomes
-
Vance RE. The NAIP/NLRC4 inflammasomes. Curr Opin Immunol (2015) 32:84-9. doi:10.1016/j.coi.2015.01.010.
-
(2015)
Curr Opin Immunol
, vol.32
, pp. 84-89
-
-
Vance, R.E.1
-
7
-
-
84927774890
-
The NAIP-NLRC4 inflammasome in innate immune detection of bacterial flagellin and type III secretion apparatus
-
Zhao Y, Shao F. The NAIP-NLRC4 inflammasome in innate immune detection of bacterial flagellin and type III secretion apparatus. Immunol Rev (2015) 265(1):85-102. doi:10.1111/imr.12293.
-
(2015)
Immunol Rev
, vol.265
, Issue.1
, pp. 85-102
-
-
Zhao, Y.1
Shao, F.2
-
8
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
Kayagaki N, Warming S, LamkanfiM, Vande Walle L, Louie S, Dong J, et al. Non-canonical inflammasome activation targets caspase-11. Nature (2011) 479(7371):117-21. doi:10.1038/nature10558.
-
(2011)
Nature
, vol.479
, Issue.7371
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande Walle, L.4
Louie, S.5
Dong, J.6
-
9
-
-
84883775365
-
Noncanonical inflammasome activation by intracellular LPS independent of TLR4
-
Kayagaki N, Wong MT, Stowe IB, Ramani SR, Gonzalez LC, Akashi-Takamura S, et al. Noncanonical inflammasome activation by intracellular LPS independent of TLR4. Science (2013) 341(6151):1246-9. doi:10.1126/science.1240248.
-
(2013)
Science
, vol.341
, Issue.6151
, pp. 1246-1249
-
-
Kayagaki, N.1
Wong, M.T.2
Stowe, I.B.3
Ramani, S.R.4
Gonzalez, L.C.5
Akashi-Takamura, S.6
-
10
-
-
84874189388
-
Caspase-11 protects against bacteria that escape the vacuole
-
Aachoui Y, Leaf IA, Hagar JA, Fontana MF, Campos CG, Zak DE, et al. Caspase-11 protects against bacteria that escape the vacuole. Science (2013) 339(6122):975-8. doi:10.1126/science.1230751.
-
(2013)
Science
, vol.339
, Issue.6122
, pp. 975-978
-
-
Aachoui, Y.1
Leaf, I.A.2
Hagar, J.A.3
Fontana, M.F.4
Campos, C.G.5
Zak, D.E.6
-
11
-
-
84883790050
-
Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock
-
Hagar JA, Powell DA, Aachoui Y, Ernst RK, Miao EA. Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock. Science (2013) 341(6151):1250-3. doi:10.1126/science.1240988.
-
(2013)
Science
, vol.341
, Issue.6151
, pp. 1250-1253
-
-
Hagar, J.A.1
Powell, D.A.2
Aachoui, Y.3
Ernst, R.K.4
Miao, E.A.5
-
12
-
-
84906571225
-
Inflammatory caspases are innate immune receptors for intracellular LPS
-
Shi J, Zhao Y, Wang Y, Gao W, Ding J, Li P, et al. Inflammatory caspases are innate immune receptors for intracellular LPS. Nature (2014) 514(7521):187-92. doi:10.1038/nature13683.
-
(2014)
Nature
, vol.514
, Issue.7521
, pp. 187-192
-
-
Shi, J.1
Zhao, Y.2
Wang, Y.3
Gao, W.4
Ding, J.5
Li, P.6
-
13
-
-
84921461716
-
Non-canonical activation of inflammatory caspases by cytosolic LPS in innate immunity
-
Yang J, Zhao Y, Shao F. Non-canonical activation of inflammatory caspases by cytosolic LPS in innate immunity. Curr Opin Immunol (2015) 32:78-83. doi:10.1016/j.coi.2015.01.007.
-
(2015)
Curr Opin Immunol
, vol.32
, pp. 78-83
-
-
Yang, J.1
Zhao, Y.2
Shao, F.3
-
14
-
-
84927732727
-
Caspase-11: arming the guards against bacterial infection
-
Stowe I, Lee B, Kayagaki N. Caspase-11: arming the guards against bacterial infection. Immunol Rev (2015) 265(1):75-84. doi:10.1111/imr.12292.
-
(2015)
Immunol Rev
, vol.265
, Issue.1
, pp. 75-84
-
-
Stowe, I.1
Lee, B.2
Kayagaki, N.3
-
15
-
-
0013922581
-
The pathogenesis of the lethal effect of anthrax toxin in the rat
-
Beall FA, Dalldorf FG. The pathogenesis of the lethal effect of anthrax toxin in the rat. J Infect Dis (1966) 116(3):377-89. doi:10.1093/infdis/116.3.377.
-
(1966)
J Infect Dis
, vol.116
, Issue.3
, pp. 377-389
-
-
Beall, F.A.1
Dalldorf, F.G.2
-
16
-
-
85047692288
-
Bacillus anthracis lethal toxin induces TNF-alpha-independent hypoxia-mediated toxicity in mice
-
Moayeri M, Haines D, Young HA, Leppla SH. Bacillus anthracis lethal toxin induces TNF-alpha-independent hypoxia-mediated toxicity in mice. J Clin Invest (2003) 112(5):670-82. doi:10.1172/JCI17991.
-
(2003)
J Clin Invest
, vol.112
, Issue.5
, pp. 670-682
-
-
Moayeri, M.1
Haines, D.2
Young, H.A.3
Leppla, S.H.4
-
17
-
-
20344391159
-
Anthrax lethal factor inhibition
-
Shoop WL, Xiong Y, Wiltsie J, Woods A, Guo J, Pivnichny JV, et al. Anthrax lethal factor inhibition. Proc Natl Acad Sci U S A (2005) 102(22):7958-63. doi:10.1073/pnas.0502159102.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.22
, pp. 7958-7963
-
-
Shoop, W.L.1
Xiong, Y.2
Wiltsie, J.3
Woods, A.4
Guo, J.5
Pivnichny, J.V.6
-
18
-
-
84901589119
-
Anthrax lethal and edema toxins in anthrax pathogenesis
-
Liu S, Moayeri M, Leppla SH. Anthrax lethal and edema toxins in anthrax pathogenesis. Trends Microbiol (2014) 22(6):317-25. doi:10.1016/j.tim.2014.02.012.
-
(2014)
Trends Microbiol
, vol.22
, Issue.6
, pp. 317-325
-
-
Liu, S.1
Moayeri, M.2
Leppla, S.H.3
-
19
-
-
84861214708
-
Anthrax lethal factor cleavage of NLRP1 is required for activation of the inflammasome
-
Levinsohn JL, Newman ZL, Hellmich KA, Fattah R, Getz MA, Liu S, et al. Anthrax lethal factor cleavage of NLRP1 is required for activation of the inflammasome. PLoS Pathog (2012) 8(3):e1002638. doi:10.1371/journal.ppat.1002638.
-
(2012)
PLoS Pathog
, vol.8
, Issue.3
-
-
Levinsohn, J.L.1
Newman, Z.L.2
Hellmich, K.A.3
Fattah, R.4
Getz, M.A.5
Liu, S.6
-
20
-
-
84869073837
-
Anthrax lethal factor cleaves mouse NLRP1B in both toxin-sensitive and toxin-resistant macrophages
-
Hellmich KA, Levinsohn JL, Fattah R, Newman ZL, Maier N, Sastalla I, et al. Anthrax lethal factor cleaves mouse NLRP1B in both toxin-sensitive and toxin-resistant macrophages. PLoS One (2012) 7(11):e49741. doi:10.1371/journal.pone.0049741.
-
(2012)
PLoS One
, vol.7
, Issue.11
-
-
Hellmich, K.A.1
Levinsohn, J.L.2
Fattah, R.3
Newman, Z.L.4
Maier, N.5
Sastalla, I.6
-
21
-
-
77954056386
-
Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1
-
Newman ZL, Printz MP, Liu S, Crown D, Breen L, Miller-Randolph S, et al. Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1. PLoS Pathog (2010) 6(5):e1000906. doi:10.1371/journal.ppat.1000906.
-
(2010)
PLoS Pathog
, vol.6
, Issue.5
-
-
Newman, Z.L.1
Printz, M.P.2
Liu, S.3
Crown, D.4
Breen, L.5
Miller-Randolph, S.6
-
22
-
-
84879508269
-
Direct proteolytic cleavage of NLRP1B Is necessary and sufficient for inflammasome activation by anthrax lethal factor
-
Chavarria-Smith J, Vance RE. Direct proteolytic cleavage of NLRP1B Is necessary and sufficient for inflammasome activation by anthrax lethal factor. PLoS Pathog (2013) 9(6):e1003452. doi:10.1371/journal.ppat.1003452.
-
(2013)
PLoS Pathog
, vol.9
, Issue.6
-
-
Chavarria-Smith, J.1
Vance, R.E.2
-
23
-
-
77955425957
-
Anthrax lethal toxin activates the inflammasome in sensitive rat macrophages
-
Newman ZL, Crown D, Leppla SH, Moayeri M. Anthrax lethal toxin activates the inflammasome in sensitive rat macrophages. Biochem Biophys Res Commun (2010) 398(4):785-9. doi:10.1016/j.bbrc.2010.07.039.
-
(2010)
Biochem Biophys Res Commun
, vol.398
, Issue.4
, pp. 785-789
-
-
Newman, Z.L.1
Crown, D.2
Leppla, S.H.3
Moayeri, M.4
-
24
-
-
31744441475
-
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
-
Boyden ED, Dietrich WF. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat Genet (2006) 38(2):240-4. doi:10.1038/ng1724.
-
(2006)
Nat Genet
, vol.38
, Issue.2
, pp. 240-244
-
-
Boyden, E.D.1
Dietrich, W.F.2
-
25
-
-
84875075579
-
Transcriptional analysis of the three NLRP1 paralogs in mice
-
Sastalla I, Crown D, Masters SL, McKenzie A, Leppla SH, Moayeri M. Transcriptional analysis of the three NLRP1 paralogs in mice. BMC Genomics (2013) 14:188. doi:10.1186/1471-2164-14-188.
-
(2013)
BMC Genomics
, vol.14
, pp. 188
-
-
Sastalla, I.1
Crown, D.2
Masters, S.L.3
McKenzie, A.4
Leppla, S.H.5
Moayeri, M.6
-
26
-
-
38049119726
-
Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome
-
Wickliffe KE, Leppla SH, Moayeri M. Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome. Cell Microbiol (2008) 10(2):332-43. doi:10.1111/j.1462-5822.2007.01044.x.
-
(2008)
Cell Microbiol
, vol.10
, Issue.2
, pp. 332-343
-
-
Wickliffe, K.E.1
Leppla, S.H.2
Moayeri, M.3
-
27
-
-
36349019887
-
Proteasomes control caspase-1 activation in anthrax lethal toxin-mediated cell killing
-
Squires RC, Muehlbauer SM, Brojatsch J. Proteasomes control caspase-1 activation in anthrax lethal toxin-mediated cell killing. J Biol Chem (2007) 282(47):34260-7. doi:10.1074/jbc. M705687200.
-
(2007)
J Biol Chem
, vol.282
, Issue.47
, pp. 34260-34267
-
-
Squires, R.C.1
Muehlbauer, S.M.2
Brojatsch, J.3
-
28
-
-
41949127121
-
Anthrax lethal toxin and salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
-
Fink SL, Bergsbaken T, Cookson BT. Anthrax lethal toxin and salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms. Proc Natl Acad Sci U S A (2008) 105(11):4312-7. doi:10.1073/pnas.0707370105.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.11
, pp. 4312-4317
-
-
Fink, S.L.1
Bergsbaken, T.2
Cookson, B.T.3
-
29
-
-
78650210802
-
Differential requirement for caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing
-
Broz P, von Moltke J, Jones JW, Vance RE, Monack DM. Differential requirement for caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing. Cell Host Microbe (2010) 8(6):471-83. doi:10.1016/j.chom.2010.11.007.
-
(2010)
Cell Host Microbe
, vol.8
, Issue.6
, pp. 471-483
-
-
Broz, P.1
von Moltke, J.2
Jones, J.W.3
Vance, R.E.4
Monack, D.M.5
-
30
-
-
84893835896
-
Activation of the NLRP1B inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation
-
Van Opdenbosch N, Gurung P, Vande Walle L, Fossoul A, Kanneganti TD, LamkanfiM. Activation of the NLRP1B inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation. Nat Commun (2014) 5:3209. doi:10.1038/ncomms4209.
-
(2014)
Nat Commun
, vol.5
, pp. 3209
-
-
Van Opdenbosch, N.1
Gurung, P.2
Vande Walle, L.3
Fossoul, A.4
Kanneganti, T.D.5
Lamkanfi, M.6
-
31
-
-
84914132432
-
Caspase-1 autoproteolysis is differentially required for NLRP1B and NLRP3 inflammasome function
-
Guey B, Bodnar M, Manie SN, Tardivel A, Petrilli V. Caspase-1 autoproteolysis is differentially required for NLRP1B and NLRP3 inflammasome function. Proc Natl Acad Sci U S A (2014) 111(48):17254-9. doi:10.1073/pnas.1415756111.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.48
, pp. 17254-17259
-
-
Guey, B.1
Bodnar, M.2
Manie, S.N.3
Tardivel, A.4
Petrilli, V.5
-
32
-
-
78651258397
-
Inflammasome sensor NLRP1B-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment
-
Moayeri M, Crown D, Newman ZL, Okugawa S, Eckhaus M, Cataisson C, et al. Inflammasome sensor NLRP1B-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment. PLoS Pathog (2010) 6(12):e1001222. doi:10.1371/journal.ppat.1001222.
-
(2010)
PLoS Pathog
, vol.6
, Issue.12
-
-
Moayeri, M.1
Crown, D.2
Newman, Z.L.3
Okugawa, S.4
Eckhaus, M.5
Cataisson, C.6
-
33
-
-
73949099407
-
Cutting edge: resistance to Bacillus anthracis infection mediated by a lethal toxin sensitive allele of NALP1B/NLRP1B
-
Terra JK, Cote CK, France B, Jenkins AL, Bozue JA, Welkos SL, et al. Cutting edge: resistance to Bacillus anthracis infection mediated by a lethal toxin sensitive allele of NALP1B/NLRP1B. J Immunol (2010) 184(1):17-20. doi:10.4049/jimmunol.0903114.
-
(2010)
J Immunol
, vol.184
, Issue.1
, pp. 17-20
-
-
Terra, J.K.1
Cote, C.K.2
France, B.3
Jenkins, A.L.4
Bozue, J.A.5
Welkos, S.L.6
-
34
-
-
84867063450
-
Rapid induction of inflammatory lipid mediators by the inflammasome in vivo
-
von Moltke J, Trinidad NJ, Moayeri M, Kintzer AF, Wang SB, van Rooijen N, et al. Rapid induction of inflammatory lipid mediators by the inflammasome in vivo. Nature (2012) 490(7418):107-11. doi:10.1038/nature11351.
-
(2012)
Nature
, vol.490
, Issue.7418
, pp. 107-111
-
-
von Moltke, J.1
Trinidad, N.J.2
Moayeri, M.3
Kintzer, A.F.4
Wang, S.B.5
van Rooijen, N.6
-
35
-
-
84859430681
-
Anthrax and the inflammasome
-
Moayeri M, Sastalla I, Leppla SH. Anthrax and the inflammasome. Microbes Infect (2012) 14(5):392-400. doi:10.1016/j.micinf.2011.12.005.
-
(2012)
Microbes Infect
, vol.14
, Issue.5
, pp. 392-400
-
-
Moayeri, M.1
Sastalla, I.2
Leppla, S.H.3
-
36
-
-
84897430736
-
Inflammasome sensor NLRP1 controls rat macrophage susceptibility to Toxoplasma gondii
-
Cirelli KM, Gorfu G, Hassan MA, Printz M, Crown D, Leppla SH, et al. Inflammasome sensor NLRP1 controls rat macrophage susceptibility to Toxoplasma gondii. PLoS Pathog (2014) 10(3):e1003927. doi:10.1371/journal.ppat.1003927.
-
(2014)
PLoS Pathog
, vol.10
, Issue.3
-
-
Cirelli, K.M.1
Gorfu, G.2
Hassan, M.A.3
Printz, M.4
Crown, D.5
Leppla, S.H.6
-
37
-
-
84890831999
-
NLRP1 is an inflammasome sensor for Toxoplasma gondii
-
Ewald SE, Chavarria-Smith J, Boothroyd JC. NLRP1 is an inflammasome sensor for Toxoplasma gondii. Infect Immun (2014) 82(1):460-8. doi:10.1128/IAI.01170-13.
-
(2014)
Infect Immun
, vol.82
, Issue.1
, pp. 460-468
-
-
Ewald, S.E.1
Chavarria-Smith, J.2
Boothroyd, J.C.3
-
38
-
-
84903369192
-
Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii
-
Gorfu G, Cirelli KM, Melo MB, Mayer-Barber K, Crown D, Koller BH, et al. Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii. mBio (2014) 5(1):e1113-7. doi:10.1128/mBio.01117-13.
-
(2014)
mBio
, vol.5
, Issue.1
, pp. e1113-e1117
-
-
Gorfu, G.1
Cirelli, K.M.2
Melo, M.B.3
Mayer-Barber, K.4
Crown, D.5
Koller, B.H.6
-
39
-
-
84901367888
-
A highly conserved toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage
-
Cavailles P, Flori P, Papapietro O, Bisanz C, Lagrange D, Pilloux L, et al. A highly conserved toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage. PLoS Pathog (2014) 10(4):e1004005. doi:10.1371/journal.ppat.1004005.
-
(2014)
PLoS Pathog
, vol.10
, Issue.4
-
-
Cavailles, P.1
Flori, P.2
Papapietro, O.3
Bisanz, C.4
Lagrange, D.5
Pilloux, L.6
-
40
-
-
0028175838
-
Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity
-
Perregaux D, Gabel CA. Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. J Biol Chem (1994) 269(21):15195-203.
-
(1994)
J Biol Chem
, vol.269
, Issue.21
, pp. 15195-15203
-
-
Perregaux, D.1
Gabel, C.A.2
-
41
-
-
0028989337
-
Potassium-inhibited processing of IL-1 beta in human monocytes
-
Walev I, Reske K, Palmer M, Valeva A, Bhakdi S. Potassium-inhibited processing of IL-1 beta in human monocytes. EMBO J (1995) 14(8):1607-14.
-
(1995)
EMBO J
, vol.14
, Issue.8
, pp. 1607-1614
-
-
Walev, I.1
Reske, K.2
Palmer, M.3
Valeva, A.4
Bhakdi, S.5
-
42
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, Roose-Girma M, et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature (2006) 440(7081):228-32. doi:10.1038/nature04515.
-
(2006)
Nature
, vol.440
, Issue.7081
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
-
43
-
-
33646017449
-
Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes
-
Ozoren N, Masumoto J, Franchi L, Kanneganti TD, Body-Malapel M, Erturk I, et al. Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes. J Immunol (2006) 176(7):4337-42. doi:10.4049/jimmunol.176.7.4337.
-
(2006)
J Immunol
, vol.176
, Issue.7
, pp. 4337-4342
-
-
Ozoren, N.1
Masumoto, J.2
Franchi, L.3
Kanneganti, T.D.4
Body-Malapel, M.5
Erturk, I.6
-
44
-
-
33748598700
-
Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival
-
Gurcel L, Abrami L, Girardin S, Tschopp J, van der Goot FG. Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell (2006) 126(6):1135-45. doi:10.1016/j.cell.2006.07.033.
-
(2006)
Cell
, vol.126
, Issue.6
, pp. 1135-1145
-
-
Gurcel, L.1
Abrami, L.2
Girardin, S.3
Tschopp, J.4
van der Goot, F.G.5
-
45
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
Petrilli V, Papin S, Dostert C, Mayor A, Martinon F, Tschopp J. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ (2007) 14(9):1583-9. doi:10.1038/sj.cdd.4402195.
-
(2007)
Cell Death Differ
, vol.14
, Issue.9
, pp. 1583-1589
-
-
Petrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
46
-
-
84879596906
-
K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter
-
Munoz-Planillo R, Kuffa P, Martinez-Colon G, Smith BL, Rajendiran TM, Nunez G. K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. Immunity (2013) 38(6):1142-53. doi:10.1016/j.immuni.2013.05.016.
-
(2013)
Immunity
, vol.38
, Issue.6
, pp. 1142-1153
-
-
Munoz-Planillo, R.1
Kuffa, P.2
Martinez-Colon, G.3
Smith, B.L.4
Rajendiran, T.M.5
Nunez, G.6
-
47
-
-
0026596550
-
Streptococcal toxic shock syndrome: synthesis of tumor necrosis factor and interleukin-1 by monocytes stimulated with pyrogenic exotoxin A and streptolysin O
-
Hackett SP, Stevens DL. Streptococcal toxic shock syndrome: synthesis of tumor necrosis factor and interleukin-1 by monocytes stimulated with pyrogenic exotoxin A and streptolysin O. J Infect Dis (1992) 165(5):879-85. doi:10.1093/infdis/165.5.879.
-
(1992)
J Infect Dis
, vol.165
, Issue.5
, pp. 879-885
-
-
Hackett, S.P.1
Stevens, D.L.2
-
48
-
-
0028176663
-
Pneumolysin stimulates production of tumor necrosis factor alpha and interleukin-1 beta by human mononuclear phagocytes
-
Houldsworth S, Andrew PW, Mitchell TJ. Pneumolysin stimulates production of tumor necrosis factor alpha and interleukin-1 beta by human mononuclear phagocytes. Infect Immun (1994) 62(4):1501-3.
-
(1994)
Infect Immun
, vol.62
, Issue.4
, pp. 1501-1503
-
-
Houldsworth, S.1
Andrew, P.W.2
Mitchell, T.J.3
-
49
-
-
70350726375
-
Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner
-
Chu J, Thomas LM, Watkins SC, Franchi L, Nunez G, Salter RD. Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner. J Leukoc Biol (2009) 86(5):1227-38. doi:10.1189/jlb.0309164.
-
(2009)
J Leukoc Biol
, vol.86
, Issue.5
, pp. 1227-1238
-
-
Chu, J.1
Thomas, L.M.2
Watkins, S.C.3
Franchi, L.4
Nunez, G.5
Salter, R.D.6
-
50
-
-
79959431647
-
K+ efflux is required for histone H3 dephosphorylation by Listeria monocytogenes listeriolysin O and other pore-forming toxins
-
Hamon MA, Cossart P. K+ efflux is required for histone H3 dephosphorylation by Listeria monocytogenes listeriolysin O and other pore-forming toxins. Infect Immun (2011) 79(7):2839-46. doi:10.1128/IAI.01243-10.
-
(2011)
Infect Immun
, vol.79
, Issue.7
, pp. 2839-2846
-
-
Hamon, M.A.1
Cossart, P.2
-
51
-
-
79251515144
-
Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4
-
McNeela EA, Burke A, Neill DR, Baxter C, Fernandes VE, Ferreira D, et al. Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4. PLoS Pathog (2010) 6(11):e1001191. doi:10.1371/journal.ppat.1001191.
-
(2010)
PLoS Pathog
, vol.6
, Issue.11
-
-
McNeela, E.A.1
Burke, A.2
Neill, D.R.3
Baxter, C.4
Fernandes, V.E.5
Ferreira, D.6
-
52
-
-
79960408020
-
The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia
-
Witzenrath M, Pache F, Lorenz D, Koppe U, Gutbier B, Tabeling C, et al. The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia. J Immunol (2011) 187(1):434-40. doi:10.4049/jimmunol.1003143.
-
(2011)
J Immunol
, vol.187
, Issue.1
, pp. 434-440
-
-
Witzenrath, M.1
Pache, F.2
Lorenz, D.3
Koppe, U.4
Gutbier, B.5
Tabeling, C.6
-
53
-
-
81455154929
-
The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release
-
Hoegen T, Tremel N, Klein M, Angele B, Wagner H, Kirschning C, et al. The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release. J Immunol (2011) 187(10):5440-51. doi:10.4049/jimmunol.1100790.
-
(2011)
J Immunol
, vol.187
, Issue.10
, pp. 5440-5451
-
-
Hoegen, T.1
Tremel, N.2
Klein, M.3
Angele, B.4
Wagner, H.5
Kirschning, C.6
-
54
-
-
84856020851
-
Streptococcus pneumoniae stimulates a STING-and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs
-
Koppe U, Hogner K, Doehn JM, Muller HC, Witzenrath M, Gutbier B, et al. Streptococcus pneumoniae stimulates a STING-and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs. J Immunol (2012) 188(2):811-7. doi:10.4049/jimmunol.1004143.
-
(2012)
J Immunol
, vol.188
, Issue.2
, pp. 811-817
-
-
Koppe, U.1
Hogner, K.2
Doehn, J.M.3
Muller, H.C.4
Witzenrath, M.5
Gutbier, B.6
-
55
-
-
84926195671
-
A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury
-
Whidbey C, Vornhagen J, Gendrin C, Boldenow E, Samson JM, Doering K, et al. A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury. EMBO Mol Med (2015) 7(4):488-505. doi:10.15252/emmm.201404883.
-
(2015)
EMBO Mol Med
, vol.7
, Issue.4
, pp. 488-505
-
-
Whidbey, C.1
Vornhagen, J.2
Gendrin, C.3
Boldenow, E.4
Samson, J.M.5
Doering, K.6
-
56
-
-
84856901248
-
Activation of the NLRP3 inflammasome by group B streptococci
-
Costa A, Gupta R, Signorino G, Malara A, Cardile F, Biondo C, et al. Activation of the NLRP3 inflammasome by group B streptococci. J Immunol (2012) 188(4):1953-60. doi:10.4049/jimmunol.1102543.
-
(2012)
J Immunol
, vol.188
, Issue.4
, pp. 1953-1960
-
-
Costa, A.1
Gupta, R.2
Signorino, G.3
Malara, A.4
Cardile, F.5
Biondo, C.6
-
57
-
-
84901020681
-
RNA and beta-hemolysin of group B Streptococcus induce interleukin-1beta (IL-1beta) by activating NLRP3 inflammasomes in mouse macrophages
-
Gupta R, Ghosh S, Monks B, DeOliveira RB, Tzeng TC, Kalantari P, et al. RNA and beta-hemolysin of group B Streptococcus induce interleukin-1beta (IL-1beta) by activating NLRP3 inflammasomes in mouse macrophages. J Biol Chem (2014) 289(20):13701-5. doi:10.1074/jbc. C114.548982.
-
(2014)
J Biol Chem
, vol.289
, Issue.20
, pp. 13701-13705
-
-
Gupta, R.1
Ghosh, S.2
Monks, B.3
DeOliveira, R.B.4
Tzeng, T.C.5
Kalantari, P.6
-
58
-
-
77749270973
-
Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2x7 receptor
-
Harder J, Franchi L, Munoz-Planillo R, Park JH, Reimer T, Nunez G. Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2x7 receptor. J Immunol (2009) 183(9):5823-9. doi:10.4049/jimmunol.0900444.
-
(2009)
J Immunol
, vol.183
, Issue.9
, pp. 5823-5829
-
-
Harder, J.1
Franchi, L.2
Munoz-Planillo, R.3
Park, J.H.4
Reimer, T.5
Nunez, G.6
-
59
-
-
84878981253
-
Reduction of streptolysin O (SLO) pore-forming activity enhances inflammasome activation
-
Keyel PA, Roth R, Yokoyama WM, Heuser JE, Salter RD. Reduction of streptolysin O (SLO) pore-forming activity enhances inflammasome activation. Toxins (Basel) (2013) 5(6):1105-18. doi:10.3390/toxins5061105.
-
(2013)
Toxins (Basel)
, vol.5
, Issue.6
, pp. 1105-1118
-
-
Keyel, P.A.1
Roth, R.2
Yokoyama, W.M.3
Heuser, J.E.4
Salter, R.D.5
-
60
-
-
70449360107
-
Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells
-
Craven RR, Gao X, Allen IC, Gris D, Bubeck Wardenburg J, McElvania-Tekippe E, et al. Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. PLoS One (2009) 4(10):e7446. doi:10.1371/journal.pone.0007446.
-
(2009)
PLoS One
, vol.4
, Issue.10
-
-
Craven, R.R.1
Gao, X.2
Allen, I.C.3
Gris, D.4
Bubeck Wardenburg, J.5
McElvania-Tekippe, E.6
-
61
-
-
84856910671
-
Staphylococcus aureus alpha-hemolysin mediates virulence in a murine model of severe pneumonia through activation of the NLRP3 inflammasome
-
Kebaier C, Chamberland RR, Allen IC, Gao X, Broglie PM, Hall JD, et al. Staphylococcus aureus alpha-hemolysin mediates virulence in a murine model of severe pneumonia through activation of the NLRP3 inflammasome. J Infect Dis (2012) 205(5):807-17. doi:10.1093/infdis/jir846.
-
(2012)
J Infect Dis
, vol.205
, Issue.5
, pp. 807-817
-
-
Kebaier, C.1
Chamberland, R.R.2
Allen, I.C.3
Gao, X.4
Broglie, P.M.5
Hall, J.D.6
-
62
-
-
84870824875
-
Neutrophil-derived IL-1beta is sufficient for abscess formation in immunity against Staphylococcus aureus in mice
-
Cho JS, Guo Y, Ramos RI, Hebroni F, Plaisier SB, Xuan C, et al. Neutrophil-derived IL-1beta is sufficient for abscess formation in immunity against Staphylococcus aureus in mice. PLoS Pathog (2012) 8(11):e1003047. doi:10.1371/journal.ppat.1003047.
-
(2012)
PLoS Pathog
, vol.8
, Issue.11
-
-
Cho, J.S.1
Guo, Y.2
Ramos, R.I.3
Hebroni, F.4
Plaisier, S.B.5
Xuan, C.6
-
63
-
-
84904039705
-
Impaired NLRP3 inflammasome expression and function in atopic dermatitis due to Th2 milieu
-
Niebuhr M, Baumert K, Heratizadeh A, Satzger I, Werfel T. Impaired NLRP3 inflammasome expression and function in atopic dermatitis due to Th2 milieu. Allergy (2014) 69(8):1058-67. doi:10.1111/all.12428.
-
(2014)
Allergy
, vol.69
, Issue.8
, pp. 1058-1067
-
-
Niebuhr, M.1
Baumert, K.2
Heratizadeh, A.3
Satzger, I.4
Werfel, T.5
-
64
-
-
1842458394
-
IL-1 and TNF-alpha play a pivotal role in the host immune response in a mouse model of Staphylococcus aureus-induced experimental brain abscess
-
Kielian T, Bearden ED, Baldwin AC, Esen N. IL-1 and TNF-alpha play a pivotal role in the host immune response in a mouse model of Staphylococcus aureus-induced experimental brain abscess. J Neuropathol Exp Neurol (2004) 63(4):381-96.
-
(2004)
J Neuropathol Exp Neurol
, vol.63
, Issue.4
, pp. 381-396
-
-
Kielian, T.1
Bearden, E.D.2
Baldwin, A.C.3
Esen, N.4
-
65
-
-
80054795572
-
Inflammasome activation and IL-1beta/IL-18 processing are influenced by distinct pathways in microglia
-
Hanamsagar R, Torres V, Kielian T. Inflammasome activation and IL-1beta/IL-18 processing are influenced by distinct pathways in microglia. J Neurochem (2011) 119(4):736-48. doi:10.1111/j.1471-4159.2011.07481.x.
-
(2011)
J Neurochem
, vol.119
, Issue.4
, pp. 736-748
-
-
Hanamsagar, R.1
Torres, V.2
Kielian, T.3
-
66
-
-
84904054033
-
Phenol-soluble modulins-critical determinants of staphylococcal virulence
-
Cheung GY, Joo HS, Chatterjee SS, Otto M. Phenol-soluble modulins-critical determinants of staphylococcal virulence. FEMS Microbiol Rev (2014) 38(4):698-719. doi:10.1111/1574-6976.12057.
-
(2014)
FEMS Microbiol Rev
, vol.38
, Issue.4
, pp. 698-719
-
-
Cheung, G.Y.1
Joo, H.S.2
Chatterjee, S.S.3
Otto, M.4
-
67
-
-
84939484873
-
Staphylococcus aureus phenol soluble modulins stimulate the release of pro-inflammatory cytokines from keratinocytes and are required for induction of skin inflammation
-
Syed AK, Reed TJ, Clark KL, Boles BR, Kahlenberg JM. Staphylococcus aureus phenol soluble modulins stimulate the release of pro-inflammatory cytokines from keratinocytes and are required for induction of skin inflammation. Infect Immun (2015) 83(9):3428-37. doi:10.1128/IAI.00401-15.
-
(2015)
Infect Immun
, vol.83
, Issue.9
, pp. 3428-3437
-
-
Syed, A.K.1
Reed, T.J.2
Clark, K.L.3
Boles, B.R.4
Kahlenberg, J.M.5
-
68
-
-
84868314254
-
Staphylococcus aureus panton-valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome
-
Holzinger D, Gieldon L, Mysore V, Nippe N, Taxman DJ, Duncan JA, et al. Staphylococcus aureus panton-valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome. J Leukoc Biol (2012) 92(5):1069-81. doi:10.1189/jlb.0112014.
-
(2012)
J Leukoc Biol
, vol.92
, Issue.5
, pp. 1069-1081
-
-
Holzinger, D.1
Gieldon, L.2
Mysore, V.3
Nippe, N.4
Taxman, D.J.5
Duncan, J.A.6
-
69
-
-
84936769144
-
Staphylococcus aureus leukocidin A/B (LukaB) kills human monocytes via host NLRP3 and ASC when extracellular, but not intracellular
-
Melehani JH, James DB, DuMont AL, Torres VJ, Duncan JA. Staphylococcus aureus leukocidin A/B (LukaB) kills human monocytes via host NLRP3 and ASC when extracellular, but not intracellular. PLoS Pathog (2015) 11(6):e1004970. doi:10.1371/journal.ppat.1004970.
-
(2015)
PLoS Pathog
, vol.11
, Issue.6
-
-
Melehani, J.H.1
James, D.B.2
DuMont, A.L.3
Torres, V.J.4
Duncan, J.A.5
-
70
-
-
70349334298
-
A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the NLRP3 inflammasome
-
Munoz-Planillo R, Franchi L, Miller LS, Nunez G. A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the NLRP3 inflammasome. J Immunol (2009) 183(6):3942-8. doi:10.4049/jimmunol.0900729.
-
(2009)
J Immunol
, vol.183
, Issue.6
, pp. 3942-3948
-
-
Munoz-Planillo, R.1
Franchi, L.2
Miller, L.S.3
Nunez, G.4
-
71
-
-
84929494277
-
Toxin-induced necroptosis is a major mechanism of Staphylococcus aureus lung damage
-
Kitur K, Parker D, Nieto P, Ahn DS, Cohen TS, Chung S, et al. Toxin-induced necroptosis is a major mechanism of Staphylococcus aureus lung damage. PLoS Pathog (2015) 11(4):e1004820. doi:10.1371/journal.ppat.1004820.
-
(2015)
PLoS Pathog
, vol.11
, Issue.4
-
-
Kitur, K.1
Parker, D.2
Nieto, P.3
Ahn, D.S.4
Cohen, T.S.5
Chung, S.6
-
72
-
-
84857404572
-
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation
-
Vince JE, Wong WW, Gentle I, Lawlor KE, Allam R, O'Reilly L, et al. Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation. Immunity (2012) 36(2):215-27. doi:10.1016/j.immuni.2012.01.012.
-
(2012)
Immunity
, vol.36
, Issue.2
, pp. 215-227
-
-
Vince, J.E.1
Wong, W.W.2
Gentle, I.3
Lawlor, K.E.4
Allam, R.5
O'Reilly, L.6
-
73
-
-
84911192502
-
RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway
-
Wang X, Jiang W, Yan Y, Gong T, Han J, Tian Z, et al. RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway. Nat Immunol (2014) 15(12):1126-33. doi:10.1038/ni.3015.
-
(2014)
Nat Immunol
, vol.15
, Issue.12
, pp. 1126-1133
-
-
Wang, X.1
Jiang, W.2
Yan, Y.3
Gong, T.4
Han, J.5
Tian, Z.6
-
74
-
-
84903480849
-
XIAP restricts TNF-and RIP3-dependent cell death and inflammasome activation
-
Yabal M, Muller N, Adler H, Knies N, Gross CJ, Damgaard RB, et al. XIAP restricts TNF-and RIP3-dependent cell death and inflammasome activation. Cell Rep (2014) 7(6):1796-808. doi:10.1016/j.celrep.2014.05.008.
-
(2014)
Cell Rep
, vol.7
, Issue.6
, pp. 1796-1808
-
-
Yabal, M.1
Muller, N.2
Adler, H.3
Knies, N.4
Gross, C.J.5
Damgaard, R.B.6
-
75
-
-
84901045151
-
Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death
-
Weng D, Marty-Roix R, Ganesan S, Proulx MK, Vladimer GI, Kaiser WJ, et al. Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death. Proc Natl Acad Sci U S A (2014) 111(20):7391-6. doi:10.1073/pnas.1403477111.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.20
, pp. 7391-7396
-
-
Weng, D.1
Marty-Roix, R.2
Ganesan, S.3
Proulx, M.K.4
Vladimer, G.I.5
Kaiser, W.J.6
-
76
-
-
84870258151
-
Enterohemorrhagic Escherichia coli specific enterohemolysin induced IL-1beta in human macrophages and EHEC-induced IL-1beta required activation of NLRP3 inflammasome
-
Zhang X, Cheng Y, Xiong Y, Ye C, Zheng H, Sun H, et al. Enterohemorrhagic Escherichia coli specific enterohemolysin induced IL-1beta in human macrophages and EHEC-induced IL-1beta required activation of NLRP3 inflammasome. PLoS One (2012) 7(11):e50288. doi:10.1371/journal.pone.0050288.
-
(2012)
PLoS One
, vol.7
, Issue.11
-
-
Zhang, X.1
Cheng, Y.2
Xiong, Y.3
Ye, C.4
Zheng, H.5
Sun, H.6
-
77
-
-
84953287497
-
Strain-and host species-specific inflammasome activation, IL-1beta release, and cell death in macrophages infected with uropathogenic Escherichia coli
-
Schaale K, Peters KM, Murthy AM, Fritzsche AK, Phan MD, Totsika M, et al. Strain-and host species-specific inflammasome activation, IL-1beta release, and cell death in macrophages infected with uropathogenic Escherichia coli. Mucosal Immunol (2015). doi:10.1038/mi.2015.44.
-
(2015)
Mucosal Immunol
-
-
Schaale, K.1
Peters, K.M.2
Murthy, A.M.3
Fritzsche, A.K.4
Phan, M.D.5
Totsika, M.6
-
78
-
-
77954521853
-
Pathogenic Vibrio activate NLRP3 inflammasome via cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-Kappa B signaling
-
Toma C, Higa N, Koizumi Y, Nakasone N, Ogura Y, McCoy AJ, et al. Pathogenic Vibrio activate NLRP3 inflammasome via cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-Kappa B signaling. J Immunol (2010) 184(9):5287-97. doi:10.4049/jimmunol.0903536.
-
(2010)
J Immunol
, vol.184
, Issue.9
, pp. 5287-5297
-
-
Toma, C.1
Higa, N.2
Koizumi, Y.3
Nakasone, N.4
Ogura, Y.5
McCoy, A.J.6
-
79
-
-
84875070662
-
Vibrio parahaemolyticus effector proteins suppress inflammasome activation by interfering with host autophagy signaling
-
Higa N, Toma C, Koizumi Y, Nakasone N, Nohara T, Masumoto J, et al. Vibrio parahaemolyticus effector proteins suppress inflammasome activation by interfering with host autophagy signaling. PLoS Pathog (2013) 9(1):e1003142. doi:10.1371/journal.ppat.1003142.
-
(2013)
PLoS Pathog
, vol.9
, Issue.1
-
-
Higa, N.1
Toma, C.2
Koizumi, Y.3
Nakasone, N.4
Nohara, T.5
Masumoto, J.6
-
80
-
-
84931271488
-
A critical role for hemolysin in Vibrio fluvialis-induced IL-1beta secretion mediated by the NLRP3 inflammasome in macrophages
-
Song L, Huang Y, Zhao M, Wang Z, Wang S, Sun H, et al. A critical role for hemolysin in Vibrio fluvialis-induced IL-1beta secretion mediated by the NLRP3 inflammasome in macrophages. Front Microbiol (2015) 6:510. doi:10.3389/fmicb.2015.00510.
-
(2015)
Front Microbiol
, vol.6
, pp. 510
-
-
Song, L.1
Huang, Y.2
Zhao, M.3
Wang, Z.4
Wang, S.5
Sun, H.6
-
81
-
-
77952325015
-
Trichothecene mycotoxins activate inflammatory response in human macrophages
-
Kankkunen P, Rintahaka J, Aalto A, Leino M, Majuri ML, Alenius H, et al. Trichothecene mycotoxins activate inflammatory response in human macrophages. J Immunol (2009) 182(10):6418-25. doi:10.4049/jimmunol.0803309.
-
(2009)
J Immunol
, vol.182
, Issue.10
, pp. 6418-6425
-
-
Kankkunen, P.1
Rintahaka, J.2
Aalto, A.3
Leino, M.4
Majuri, M.L.5
Alenius, H.6
-
82
-
-
84866156921
-
Encephalomyocarditis virus viroporin 2B activates NLRP3 inflammasome
-
Ito M, Yanagi Y, Ichinohe T. Encephalomyocarditis virus viroporin 2B activates NLRP3 inflammasome. PLoS Pathog (2012) 8(8):e1002857. doi:10.1371/journal.ppat.1002857.
-
(2012)
PLoS Pathog
, vol.8
, Issue.8
-
-
Ito, M.1
Yanagi, Y.2
Ichinohe, T.3
-
83
-
-
84873178376
-
Role of the inflammasome in defense against venoms
-
Palm NW, Medzhitov R. Role of the inflammasome in defense against venoms. Proc Natl Acad Sci U S A (2013) 110(5):1809-14. doi:10.1073/pnas.1221476110.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.5
, pp. 1809-1814
-
-
Palm, N.W.1
Medzhitov, R.2
-
84
-
-
84899802969
-
Host-derived, pore-forming toxin-like protein and trefoil factor complex protects the host against microbial infection
-
Xiang Y, Yan C, Guo X, Zhou K, Li S, Gao Q, et al. Host-derived, pore-forming toxin-like protein and trefoil factor complex protects the host against microbial infection. Proc Natl Acad Sci U S A (2014) 111(18):6702-7. doi:10.1073/pnas.1321317111.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.18
, pp. 6702-6707
-
-
Xiang, Y.1
Yan, C.2
Guo, X.3
Zhou, K.4
Li, S.5
Gao, Q.6
-
85
-
-
79959213985
-
Bacterial protein toxins that modify host regulatory GTPases
-
Aktories K. Bacterial protein toxins that modify host regulatory GTPases. Nat Rev Microbiol (2011) 9(7):487-98. doi:10.1038/nrmicro2592.
-
(2011)
Nat Rev Microbiol
, vol.9
, Issue.7
, pp. 487-498
-
-
Aktories, K.1
-
86
-
-
84876282419
-
Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1
-
Keestra AM, Winter MG, Auburger JJ, Frassle SP, Xavier MN, Winter SE, et al. Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1. Nature (2013) 496(7444):233-7. doi:10.1038/nature12025.
-
(2013)
Nature
, vol.496
, Issue.7444
, pp. 233-237
-
-
Keestra, A.M.1
Winter, M.G.2
Auburger, J.J.3
Frassle, S.P.4
Xavier, M.N.5
Winter, S.E.6
-
87
-
-
84907270863
-
Innate immune sensing of bacterial modifications of Rho GtPases by the Pyrin inflammasome
-
Xu H, Yang J, Gao W, Li L, Li P, Zhang L, et al. Innate immune sensing of bacterial modifications of Rho GtPases by the Pyrin inflammasome. Nature (2014) 513(7517):237-41. doi:10.1038/nature13449.
-
(2014)
Nature
, vol.513
, Issue.7517
, pp. 237-241
-
-
Xu, H.1
Yang, J.2
Gao, W.3
Li, L.4
Li, P.5
Zhang, L.6
-
88
-
-
0030745449
-
Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever
-
The International Fmf Consortium. Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever. Cell (1997) 90(4):797-807. doi:10.1016/S0092-8674(00)80539-5.
-
(1997)
Cell
, vol.90
, Issue.4
, pp. 797-807
-
-
-
89
-
-
16944365196
-
A candidate gene for familial Mediterranean fever
-
French FMF Consortium. A candidate gene for familial Mediterranean fever. Nat Genet (1997) 17(1):25-31. doi:10.1038/ng0997-25.
-
(1997)
Nat Genet
, vol.17
, Issue.1
, pp. 25-31
-
-
-
90
-
-
77955482224
-
Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome
-
Ng J, Hirota SA, Gross O, Li Y, Ulke-Lemee A, Potentier MS, et al. Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome. Gastroenterology (2010) 139(2):.e1-3. doi:10.1053/j.gastro.2010.04.005.
-
(2010)
Gastroenterology
, vol.139
, Issue.2
, pp. e1-e3
-
-
Ng, J.1
Hirota, S.A.2
Gross, O.3
Li, Y.4
Ulke-Lemee, A.5
Potentier, M.S.6
-
91
-
-
84901651706
-
The inflammasome Pyrin contributes to pertussis toxin-induced IL-1beta synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis
-
Dumas A, Amiable N, de Rivero Vaccari JP, Chae JJ, Keane RW, Lacroix S, et al. The inflammasome Pyrin contributes to pertussis toxin-induced IL-1beta synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis. PLoS Pathog (2014) 10(5):e1004150. doi:10.1371/journal.ppat.1004150.
-
(2014)
PLoS Pathog
, vol.10
, Issue.5
-
-
Dumas, A.1
Amiable, N.2
de Rivero Vaccari, J.P.3
Chae, J.J.4
Keane, R.W.5
Lacroix, S.6
-
92
-
-
84906490272
-
Blockade of the PI-3K signalling pathway by the Aggregatibacter actinomycetemcomitans cytolethal distending toxin induces macrophages to synthesize and secrete pro-inflammatory cytokines
-
Shenker BJ, Walker LP, Zekavat A, Dlakic M, Boesze-Battaglia K. Blockade of the PI-3K signalling pathway by the Aggregatibacter actinomycetemcomitans cytolethal distending toxin induces macrophages to synthesize and secrete pro-inflammatory cytokines. Cell Microbiol (2014) 16(9):1391-404. doi:10.1111/cmi.12299.
-
(2014)
Cell Microbiol
, vol.16
, Issue.9
, pp. 1391-1404
-
-
Shenker, B.J.1
Walker, L.P.2
Zekavat, A.3
Dlakic, M.4
Boesze-Battaglia, K.5
-
93
-
-
84925372815
-
Aggregatibacter actinomycetemcomitans cytolethal distending toxin activates the NLRP3 inflammasome in human macrophages, leading to the release of proinflammatory cytokines
-
Shenker BJ, Ojcius DM, Walker LP, Zekavat A, Scuron MD, Boesze-Battaglia K. Aggregatibacter actinomycetemcomitans cytolethal distending toxin activates the NLRP3 inflammasome in human macrophages, leading to the release of proinflammatory cytokines. Infect Immun (2015) 83(4):1487-96. doi:10.1128/IAI.03132-14.
-
(2015)
Infect Immun
, vol.83
, Issue.4
, pp. 1487-1496
-
-
Shenker, B.J.1
Ojcius, D.M.2
Walker, L.P.3
Zekavat, A.4
Scuron, M.D.5
Boesze-Battaglia, K.6
-
94
-
-
84908424472
-
Shigella Ipah7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages
-
Suzuki S, Mimuro H, Kim M, Ogawa M, Ashida H, Toyotome T, et al. Shigella Ipah7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages. Proc Natl Acad Sci U S A (2014) 111(40):E4254-63. doi:10.1073/pnas.1324021111.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.40
, pp. E4254-E4263
-
-
Suzuki, S.1
Mimuro, H.2
Kim, M.3
Ogawa, M.4
Ashida, H.5
Toyotome, T.6
-
95
-
-
70249139539
-
Pulmonary inflammation triggered by ricin toxin requires macrophages and IL-1 signaling
-
Lindauer ML, Wong J, Iwakura Y, Magun BE. Pulmonary inflammation triggered by ricin toxin requires macrophages and IL-1 signaling. J Immunol (2009) 183(2):1419-26. doi:10.4049/jimmunol.0901119.
-
(2009)
J Immunol
, vol.183
, Issue.2
, pp. 1419-1426
-
-
Lindauer, M.L.1
Wong, J.2
Iwakura, Y.3
Magun, B.E.4
-
96
-
-
84857866006
-
Ricin and Shiga toxins: effects on host cell signal transduction
-
Jandhyala DM, Thorpe CM, Magun B. Ricin and Shiga toxins: effects on host cell signal transduction. Curr Top Microbiol Immunol (2012) 357:41-65. doi:10.1007/82_2011_181.
-
(2012)
Curr Top Microbiol Immunol
, vol.357
, pp. 41-65
-
-
Jandhyala, D.M.1
Thorpe, C.M.2
Magun, B.3
-
97
-
-
79952076264
-
Ricin toxin activates the NALP3 inflammasome
-
Lindauer M, Wong J, Magun B. Ricin toxin activates the NALP3 inflammasome. Toxins (Basel) (2010) 2(6):1500-14. doi:10.3390/toxins2061500.
-
(2010)
Toxins (Basel)
, vol.2
, Issue.6
, pp. 1500-1514
-
-
Lindauer, M.1
Wong, J.2
Magun, B.3
-
98
-
-
77956397771
-
Inflammasome activation by adenylate cyclase toxin directs Th17 responses and protection against Bordetella pertussis
-
Dunne A, Ross PJ, Pospisilova E, Masin J, Meaney A, Sutton CE, et al. Inflammasome activation by adenylate cyclase toxin directs Th17 responses and protection against Bordetella pertussis. J Immunol (2010) 185(3):1711-9. doi:10.4049/jimmunol.1000105.
-
(2010)
J Immunol
, vol.185
, Issue.3
, pp. 1711-1719
-
-
Dunne, A.1
Ross, P.J.2
Pospisilova, E.3
Masin, J.4
Meaney, A.5
Sutton, C.E.6
-
99
-
-
84872154844
-
The mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signaling
-
Desel C, Werninghaus K, Ritter M, Jozefowski K, Wenzel J, Russkamp N, et al. The mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signaling. PLoS One (2013) 8(1):e53531. doi:10.1371/journal.pone.0053531.
-
(2013)
PLoS One
, vol.8
, Issue.1
-
-
Desel, C.1
Werninghaus, K.2
Ritter, M.3
Jozefowski, K.4
Wenzel, J.5
Russkamp, N.6
-
100
-
-
79956215858
-
Escherichia coli heat-labile enterotoxin promotes protective Th17 responses against infection by driving innate IL-1 and IL-23 production
-
Brereton CF, Sutton CE, Ross PJ, Iwakura Y, Pizza M, Rappuoli R, et al. Escherichia coli heat-labile enterotoxin promotes protective Th17 responses against infection by driving innate IL-1 and IL-23 production. J Immunol (2011) 186(10):5896-906. doi:10.4049/jimmunol.1003789.
-
(2011)
J Immunol
, vol.186
, Issue.10
, pp. 5896-5906
-
-
Brereton, C.F.1
Sutton, C.E.2
Ross, P.J.3
Iwakura, Y.4
Pizza, M.5
Rappuoli, R.6
-
101
-
-
84927646951
-
Cholera toxin, and the related nontoxic adjuvants mmCT and dmLT, promote human Th17 responses via cyclic AMP-protein kinase A and inflammasome-dependent IL-1 signaling
-
Larena M, Holmgren J, Lebens M, Terrinoni M, Lundgren A. Cholera toxin, and the related nontoxic adjuvants mmCT and dmLT, promote human Th17 responses via cyclic AMP-protein kinase A and inflammasome-dependent IL-1 signaling. J Immunol (2015) 194(8):3829-39. doi:10.4049/jimmunol.1401633.
-
(2015)
J Immunol
, vol.194
, Issue.8
, pp. 3829-3839
-
-
Larena, M.1
Holmgren, J.2
Lebens, M.3
Terrinoni, M.4
Lundgren, A.5
-
102
-
-
84878022309
-
Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome
-
Shenderov K, Barber DL, Mayer-Barber KD, Gurcha SS, Jankovic D, Feng CG, et al. Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome. J Immunol (2013) 190(11):5722-30. doi:10.4049/jimmunol.1203343.
-
(2013)
J Immunol
, vol.190
, Issue.11
, pp. 5722-5730
-
-
Shenderov, K.1
Barber, D.L.2
Mayer-Barber, K.D.3
Gurcha, S.S.4
Jankovic, D.5
Feng, C.G.6
-
103
-
-
84931567250
-
The inflammasome: learning from bacterial evasion strategies
-
Shin S, Brodsky IE. The inflammasome: learning from bacterial evasion strategies. Semin Immunol (2015) 27(2):102-10. doi:10.1016/j.smim.2015.03.006.
-
(2015)
Semin Immunol
, vol.27
, Issue.2
, pp. 102-110
-
-
Shin, S.1
Brodsky, I.E.2
|