A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury

EMBO Molecular Medicine

Volumn 7, Issue 4, 2015, Pages 488-505

  Whidbey, Christopher ^a   Vornhagen, Jay ^a   Gendrin, Claire ^a   Boldenow, Erica ^a   Samson, Jenny Mae ^a   Doering, Kenji ^a   Ngo, Lisa ^a   Ezekwe, Ejiofor A D ^b   Gundlach, Jens H ^a   Elovitz, Michal A ^c   Liggitt, Denny ^d   Duncan, Joseph A ^b   Adams Waldorf, Kristina M ^d   Rajagopal, Lakshmi ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Cell death; Group B streptococcus; Hemolytic pigment; Inflammasome; Preterm birth

Indexed keywords

CRYOPYRIN; INTERLEUKIN 1BETA CONVERTING ENZYME; PIGMENT; BACTERIAL TOXIN; MEMBRANE LIPID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOLYSIS; ERYTHROCYTE; FEMALE; FETAL INJURY; HEMOLYSIS; HOST CELL; HUMAN; HUMAN CELL; INJURY; LIPID BILAYER; MACROPHAGE; MALE; MEMBRANE PERMEABILITY; NONHUMAN; POTASSIUM CELL LEVEL; POTASSIUM TRANSPORT; PREMATURE LABOR; PRIORITY JOURNAL; STREPTOCOCCUS AGALACTIAE; ANIMAL; CELL MEMBRANE PERMEABILITY; FETUS DISEASE; IMMUNOLOGY; KNOCKOUT MOUSE; MICROBIOLOGY; MOUSE; PATHOGENICITY; PATHOLOGY; PYROPTOSIS; STREPTOCOCCUS INFECTION; TUMOR CELL LINE;

ANIMALS; BACTERIAL TOXINS; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; FEMALE; FETAL DISEASES; HUMANS; MALE; MEMBRANE LIPIDS; MICE; MICE, KNOCKOUT; PYROPTOSIS; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS AGALACTIAE;

EID: 84926195671     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201404883     Document Type: Article

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