-
1
-
-
1642285783
-
NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
DOI 10.1016/S1074-7613(04)00046-9, PII S1074761304000469
-
Agostini L., Martinon F., Burns K., McDermott M. F., Hawkins P. N., and, Tschopp J., (2004) NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20, 319-325. (Pubitemid 38388233)
-
(2004)
Immunity
, vol.20
, Issue.3
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
2
-
-
0036899758
-
De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): A new member of the expanding family of pyrin-associated autoinflammatory diseases
-
DOI 10.1002/art.10688
-
Aksentijevich I., Nowak M., Mallah M., et al. (2002) De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases. Arthritis Rheum. 46, 3340-3348. (Pubitemid 35453546)
-
(2002)
Arthritis and Rheumatism
, vol.46
, Issue.12
, pp. 3340-3348
-
-
Aksentijevich, I.1
Nowak, M.2
Mallah, M.3
Chae, J.J.4
Watford, W.T.5
Hofmann, S.R.6
Stein, L.7
Russo, R.8
Goldsmith, D.9
Dent, P.10
Rosenberg, H.F.11
Austin, F.12
Remmers, E.F.13
Balow Jr., J.E.14
Rosenzweig, S.15
Komarow, H.16
Shoham, N.G.17
Wood, G.18
Jones, J.19
Mangra, N.20
Carrero, H.21
Adams, B.S.22
Moore, T.L.23
Schikler, K.24
Hoffman, H.25
Lovell, D.J.26
Lipnick, R.27
Barron, K.28
O'Shea, J.J.29
Kastner, D.L.30
Goldbach-Mansky, R.31
more..
-
3
-
-
0347363607
-
ATP-induced ATP release from astrocytes
-
Anderson C. M., Bergher J. P., and, Swanson R. A., (2004) ATP-induced ATP release from astrocytes. J. Neurochem. 88, 246-256. (Pubitemid 38030227)
-
(2004)
Journal of Neurochemistry
, vol.88
, Issue.1
, pp. 246-256
-
-
Anderson, C.M.1
Bergher, J.P.2
Swanson, R.A.3
-
4
-
-
0025865829
-
The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration
-
Andersson P. B., Perry V. H., and, Gordon S., (1991) The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration. Neuroscience 42, 201-214.
-
(1991)
Neuroscience
, vol.42
, pp. 201-214
-
-
Andersson, P.B.1
Perry, V.H.2
Gordon, S.3
-
5
-
-
10444241090
-
Clinical and genetic heterogeneity among Spanish patients with recurrent autoinflammatory syndromes associated with the CIAS1/PYPAF1/NALP3 gene
-
DOI 10.1002/art.20633
-
Arostegui J. I., Aldea A., Modesto C., et al. (2004) Clinical and genetic heterogeneity among Spanish patients with recurrent autoinflammatory syndromes associated with the CIAS1/PYPAF1/NALP3 gene. Arthritis Rheum. 50, 4045-4050. (Pubitemid 39643954)
-
(2004)
Arthritis and Rheumatism
, vol.50
, Issue.12
, pp. 4045-4050
-
-
Arostegui, J.I.1
Aldea, A.2
Modesto, C.3
Rua, M.J.4
Arguelles, F.5
Gonzalez-Ensenat, M.A.6
Ramos, E.7
Rius, J.8
Plaza, S.9
Vives, J.10
Yague, J.11
-
6
-
-
77950543908
-
A somatic NLRP3 mutation as a cause of a sporadic case of chronic infantile neurologic, cutaneous, articular syndrome/neonatal-onset multisystem inflammatory disease: Novel evidence of the role of low-level mosaicism as the pathophysiologic mechanism underlying mendelian inherited diseases
-
Arostegui J. I., Lopez Saldana M. D., Pascal M., et al. (2010) A somatic NLRP3 mutation as a cause of a sporadic case of chronic infantile neurologic, cutaneous, articular syndrome/neonatal-onset multisystem inflammatory disease: Novel evidence of the role of low-level mosaicism as the pathophysiologic mechanism underlying mendelian inherited diseases. Arthritis Rheum. 62, 1158-1166.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 1158-1166
-
-
Arostegui, J.I.1
Lopez Saldana, M.D.2
Pascal, M.3
-
7
-
-
69949175486
-
Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors
-
Babelova A., Moreth K., Tsalastra-Greul W., et al. (2009) Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J. Biol. Chem. 284, 24035-24048.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 24035-24048
-
-
Babelova, A.1
Moreth, K.2
Tsalastra-Greul, W.3
-
8
-
-
0025787798
-
Alpha-toxin of Staphylococcus aureus
-
Bhakdi S., and, Tranum-Jensen J., (1991) Alpha-toxin of Staphylococcus aureus. Microbiol. Rev. 55, 733-751. (Pubitemid 21895174)
-
(1991)
Microbiological Reviews
, vol.55
, Issue.4
, pp. 733-751
-
-
Bhakdi, S.1
Tranum-Jensen, J.2
-
9
-
-
69549119940
-
Molecular mechanisms involved in inflammasome activation
-
Bryant C., and, Fitzgerald K. A., (2009) Molecular mechanisms involved in inflammasome activation. Trends Cell Biol. 19, 455-464.
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 455-464
-
-
Bryant, C.1
Fitzgerald, K.A.2
-
10
-
-
0032053941
-
2 receptors
-
DOI 10.1002/(SICI)1098-1136(199804)22:4<360::AID-GLIA5>3.0.CO;2-7
-
Chen W. C., and, Chen C. C., (1998) ATP-induced arachidonic acid release in cultured astrocytes is mediated by Gi protein coupled P2Y1 and P2Y2 receptors. Glia 22, 360-370. (Pubitemid 28129713)
-
(1998)
GLIA
, vol.22
, Issue.4
, pp. 360-370
-
-
Chen, W.C.1
Chen, C.-C.2
-
11
-
-
70350726375
-
Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner
-
Chu J., Thomas L. M., Watkins S. C., Franchi L., Nunez G., and, Salter R. D., (2009) Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner. J. Leukoc. Biol. 86, 1227-1238.
-
(2009)
J. Leukoc. Biol.
, vol.86
, pp. 1227-1238
-
-
Chu, J.1
Thomas, L.M.2
Watkins, S.C.3
Franchi, L.4
Nunez, G.5
Salter, R.D.6
-
12
-
-
70449360107
-
Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells
-
Craven R. R., Gao X., Allen I. C., Gris D., Bubeck Wardenburg J., McElvania-Tekippe E., Ting J. P., and, Duncan J. A., (2009) Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. PLoS ONE 4, e7446.
-
(2009)
PLoS ONE
, vol.4
-
-
Craven, R.R.1
Gao, X.2
Allen, I.C.3
Gris, D.4
Bubeck Wardenburg, J.5
McElvania-Tekippe, E.6
Ting, J.P.7
Duncan, J.A.8
-
13
-
-
34047261260
-
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
-
DOI 10.1074/jbc.M608083200
-
Cruz C. M., Rinna A., Forman H. J., Ventura A. L., Persechini P. M., and, Ojcius D. M., (2007) ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. J. Biol. Chem. 282, 2871-2879. (Pubitemid 47084344)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.5
, pp. 2871-2879
-
-
Cruz, C.M.1
Rinna, A.2
Forman, H.J.3
Ventura, A.L.M.4
Persechini, P.M.5
Ojcius, D.M.6
-
14
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
DOI 10.1126/science.1156995
-
Dostert C., Petrilli V., Van Bruggen R., Steele C., Mossman B. T., and, Tschopp J., (2008) Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320, 674-677. (Pubitemid 351928351)
-
(2008)
Science
, vol.320
, Issue.5876
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
15
-
-
78751680161
-
Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis
-
Dumont A. L., Nygaard T. K., Watkins R. L., Smith A., Kozhaya L., Kreiswirth B. N., Shopsin B., Unutmaz D., Voyich J. M., and, Torres V. J., (2011) Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis. Mol. Microbiol. 79, 814-825.
-
(2011)
Mol. Microbiol.
, vol.79
, pp. 814-825
-
-
Dumont, A.L.1
Nygaard, T.K.2
Watkins, R.L.3
Smith, A.4
Kozhaya, L.5
Kreiswirth, B.N.6
Shopsin, B.7
Unutmaz, D.8
Voyich, J.M.9
Torres, V.J.10
-
16
-
-
70449448992
-
Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome
-
Duncan J. A., Gao X., Huang M. T., O'Connor B. P., Thomas C. E., Willingham S. B., Bergstralh D. T., Jarvis G. A., Sparling P. F., and, Ting J. P., (2009) Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome. J. Immunol. 182, 6460-6469.
-
(2009)
J. Immunol.
, vol.182
, pp. 6460-6469
-
-
Duncan, J.A.1
Gao, X.2
Huang, M.T.3
O'Connor, B.P.4
Thomas, C.E.5
Willingham, S.B.6
Bergstralh, D.T.7
Jarvis, G.A.8
Sparling, P.F.9
Ting, J.P.10
-
17
-
-
33646860198
-
Central role for MyD88 in the responses of microglia to pathogen-associated molecular patterns
-
Esen N., and, Kielian T., (2006) Central role for MyD88 in the responses of microglia to pathogen-associated molecular patterns. J. Immunol. 176, 6802-6811. (Pubitemid 43787863)
-
(2006)
Journal of Immunology
, vol.176
, Issue.11
, pp. 6802-6811
-
-
Esen, N.1
Kielian, T.2
-
19
-
-
0942287664
-
Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus
-
DOI 10.1046/j.1471-4159.2003.02202.x
-
Esen N., Tanga F. Y., DeLeo J. A., and, Kielian T., (2004) Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus. J. Neurochem. 88, 746-758. (Pubitemid 38140218)
-
(2004)
Journal of Neurochemistry
, vol.88
, Issue.3
, pp. 746-758
-
-
Esen, N.1
Tanga, F.Y.2
DeLeo, J.A.3
Kielian, T.4
-
20
-
-
34547101484
-
+ for caspase-1 activation induced by intracellular and extracellular bacteria
-
DOI 10.1074/jbc.M610762200
-
Franchi L., Kanneganti T. D., Dubyak G. R., and, Nunez G., (2007) Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria. J. Biol. Chem. 282, 18810-18818. (Pubitemid 47100181)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.26
, pp. 18810-18818
-
-
Franchi, L.1
Kanneganti, T.-D.2
Dubyak, G.R.3
Nunez, G.4
-
21
-
-
70449519526
-
MyD88 expression by CNS-resident cells is pivotal for eliciting protective immunity in brain abscesses
-
Garg S., Nichols J. R., Esen N., et al. (2009) MyD88 expression by CNS-resident cells is pivotal for eliciting protective immunity in brain abscesses. ASN Neuro 1, e00007.
-
(2009)
ASN Neuro
, vol.1
-
-
Garg, S.1
Nichols, J.R.2
Esen, N.3
-
22
-
-
65649140025
-
Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis
-
Gasse P., Riteau N., Charron S., et al. (2009) Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. Am. J. Respir. Crit. Care Med. 179, 903-913.
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.179
, pp. 903-913
-
-
Gasse, P.1
Riteau, N.2
Charron, S.3
-
23
-
-
33745737686
-
Pharmacology of P2X channels
-
DOI 10.1007/s00424-006-0070-9
-
Gever J. R., Cockayne D. A., Dillon M. P., Burnstock G., and, Ford A. P., (2006) Pharmacology of P2X channels. Pflugers Arch. 452, 513-537. (Pubitemid 44015088)
-
(2006)
Pflugers Archiv European Journal of Physiology
, vol.452
, Issue.5
, pp. 513-537
-
-
Gever, J.R.1
Cockayne, D.A.2
Dillon, M.P.3
Burnstock, G.4
Ford, A.P.D.W.5
-
24
-
-
0032476021
-
Characterization of a novel structural member, LukE-LukD, of the bi-component staphylococcal leucotoxins family
-
DOI 10.1016/S0014-5793(98)01130-2, PII S0014579398011302
-
Gravet A., Colin D. A., Keller D., Girardot R., Monteil H., and, Prevost G., (1998) Characterization of a novel structural member, LukE-LukD, of the bi-component staphylococcal leucotoxins family. FEBS Lett. 436, 202-208. (Pubitemid 28468556)
-
(1998)
FEBS Letters
, vol.436
, Issue.2
, pp. 202-208
-
-
Gravet, A.1
Colin, D.A.2
Keller, D.3
Giradot, R.4
Monteil, H.5
Prevost, G.6
-
25
-
-
0034177562
-
Survival of Staphylococcus aureus inside neutrophils contributes to infection
-
Gresham H. D., Lowrance J. H., Caver T. E., Wilson B. S., Cheung A. L., and, Lindberg F. P., (2000) Survival of Staphylococcus aureus inside neutrophils contributes to infection. J. Immunol. 164, 3713-3722. (Pubitemid 30169827)
-
(2000)
Journal of Immunology
, vol.164
, Issue.7
, pp. 3713-3722
-
-
Gresham, H.D.1
Lowrance, J.H.2
Caver, T.E.3
Wilson, B.S.4
Cheung, A.L.5
Lindberg, F.P.6
-
26
-
-
77955475968
-
NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses
-
Gris D., Ye Z., Iocca H. A., Wen H., Craven R. R., Gris P., Huang M., Schneider M., Miller S. D., and, Ting J. P., (2010) NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. J. Immunol. 185, 974-981.
-
(2010)
J. Immunol.
, vol.185
, pp. 974-981
-
-
Gris, D.1
Ye, Z.2
Iocca, H.A.3
Wen, H.4
Craven, R.R.5
Gris, P.6
Huang, M.7
Schneider, M.8
Miller, S.D.9
Ting, J.P.10
-
27
-
-
47349083019
-
Microglia and astrocyte activation by toll-like receptor ligands: Modulation by PPAR-gamma agonists
-
Gurley C., Nichols J., Liu S., Phulwani N. K., Esen N., and, Kielian T., (2008) Microglia and astrocyte activation by toll-like receptor ligands: modulation by PPAR-gamma agonists. PPAR Res. 2008, 453120.
-
(2008)
PPAR Res.
, vol.2008
, pp. 453120
-
-
Gurley, C.1
Nichols, J.2
Liu, S.3
Phulwani, N.K.4
Esen, N.5
Kielian, T.6
-
28
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
Halle A., Hornung V., Petzold G. C., Stewart C. R., Monks B. G., Reinheckel T., Fitzgerald K. A., Latz E., Moore K. J., and, Golenbock D. T., (2008) The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat. Immunol. 9, 857-865.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
Fitzgerald, K.A.7
Latz, E.8
Moore, K.J.9
Golenbock, D.T.10
-
29
-
-
0035179970
-
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
-
DOI 10.1038/ng756
-
Hoffman H. M., Mueller J. L., Broide D. H., Wanderer A. A., and, Kolodner R. D., (2001) Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat. Genet. 29, 301-305. (Pubitemid 33096455)
-
(2001)
Nature Genetics
, vol.29
, Issue.3
, pp. 301-305
-
-
Hoffman, H.M.1
Mueller, J.L.2
Broide, D.H.3
Wanderer, A.A.4
Kolodner, R.D.5
-
30
-
-
78649396261
-
The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18
-
Jha S., Srivastava S. Y., Brickey W. J., Iocca H., Toews A., Morrison J. P., Chen V. S., Gris D., Matsushima G. K., and, Ting J. P., (2010) The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18. J. Neurosci. 30, 15811-15820.
-
(2010)
J. Neurosci.
, vol.30
, pp. 15811-15820
-
-
Jha, S.1
Srivastava, S.Y.2
Brickey, W.J.3
Iocca, H.4
Toews, A.5
Morrison, J.P.6
Chen, V.S.7
Gris, D.8
Matsushima, G.K.9
Ting, J.P.10
-
31
-
-
3042515270
-
Prevalence of antimicrobial resistance in bacteria isolated from central nervous system specimens as reported by U.S. hospital laboratories from 2000 to 2002
-
Jones M. E., Draghi D. C., Karlowsky J. A., Sahm D. F., and, Bradley J. S., (2004) Prevalence of antimicrobial resistance in bacteria isolated from central nervous system specimens as reported by U.S. hospital laboratories from 2000 to 2002. Ann. Clin. Microbiol. Antimicrob. 3, 3.
-
(2004)
Ann. Clin. Microbiol. Antimicrob.
, vol.3
, pp. 3
-
-
Jones, M.E.1
Draghi, D.C.2
Karlowsky, J.A.3
Sahm, D.F.4
Bradley, J.S.5
-
32
-
-
77953464750
-
(1,3)-beta-glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages
-
Kankkunen P., Teirila L., Rintahaka J., Alenius H., Wolff H., and, Matikainen S., (2010) (1,3)-beta-glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages. J. Immunol. 184, 6335-6342.
-
(2010)
J. Immunol.
, vol.184
, pp. 6335-6342
-
-
Kankkunen, P.1
Teirila, L.2
Rintahaka, J.3
Alenius, H.4
Wolff, H.5
Matikainen, S.6
-
33
-
-
0033870421
-
Proinflammatory cytokine, chemokine, and cellular adhesion molecule expression during the acute phase of experimental brain abscess development
-
Kielian T., and, Hickey W. F., (2000) Proinflammatory cytokine, chemokine, and cellular adhesion molecule expression during the acute phase of experimental brain abscess development. Am. J. Pathol. 157, 647-658. (Pubitemid 30626923)
-
(2000)
American Journal of Pathology
, vol.157
, Issue.2
, pp. 647-658
-
-
Kielian, T.1
Hickey, W.F.2
-
34
-
-
0036709090
-
Characterization of microglial responses to Staphylococcus aureus: Effects on cytokine, costimulatory molecule, and Toll-like receptor expression
-
DOI 10.1016/S0165-5728(02)00216-3, PII S0165572802002163
-
Kielian T., Mayes P., and, Kielian M., (2002) Characterization of microglial responses to Staphylococcus aureus: effects on cytokine, costimulatory molecule, and Toll-like receptor expression. J. Neuroimmunol. 130, 86-99. (Pubitemid 35239996)
-
(2002)
Journal of Neuroimmunology
, vol.130
, Issue.1-2
, pp. 86-99
-
-
Kielian, T.1
Mayes, P.2
Kielian, M.3
-
35
-
-
1842458394
-
IL-1 and TNF-α Play A Pivotal Role in the Host Immune Response in A Mouse Model of Staphylococcus aureus-Induced Experimental Brain Abscess
-
Kielian T., Bearden E. D., Baldwin A. C., and, Esen N., (2004a) IL-1 and TNF-alpha play a pivotal role in the host immune response in a mouse model of Staphylococcus aureus-induced experimental brain abscess. J. Neuropathol. Exp. Neurol. 63, 381-396. (Pubitemid 38429034)
-
(2004)
Journal of Neuropathology and Experimental Neurology
, vol.63
, Issue.4
, pp. 381-396
-
-
Kielian, T.1
Bearden, E.D.2
Baldwin, A.C.3
Esen, N.4
-
36
-
-
4444360212
-
S. aureus-dependent microglial activation is selectively attenuated by the cyclopentenone prostaglandin 15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2)
-
DOI 10.1111/j.1471-4159.2004.02579.x
-
Kielian T., McMahon M., Bearden E. D., Baldwin A. C., Drew P. D., and, Esen N., (2004b) S. aureus-dependent microglial activation is selectively attenuated by the cyclopentenone prostaglandin 15-deoxy-Delta12,14- prostaglandin J2 (15d-PGJ2). J. Neurochem. 90, 1163-1172. (Pubitemid 39167349)
-
(2004)
Journal of Neurochemistry
, vol.90
, Issue.5
, pp. 1163-1172
-
-
Kielian, T.1
McMahon, M.2
Bearden, E.D.3
Baldwin, A.C.4
Drew, P.D.5
Esen, N.6
-
37
-
-
14844348476
-
Toll-like receptor 2 (TLR2) is pivotal for recognition of S. aureus peptidoglycan but not intact bacteria by microglia
-
DOI 10.1002/glia.20144
-
Kielian T., Esen N., and, Bearden E. D., (2005) Toll-like receptor 2 (TLR2) is pivotal for recognition of S. aureus peptidoglycan but not intact bacteria by microglia. Glia 49, 567-576. (Pubitemid 40353841)
-
(2005)
GLIA
, vol.49
, Issue.4
, pp. 567-576
-
-
Kielian, T.1
Esen, N.2
Bearden, E.D.3
-
38
-
-
33947685006
-
MyD88-dependent signals are essential for the host immune response in experimental brain abscess
-
Kielian T., Phulwani N. K., Esen N., Syed M. M., Haney A. C., McCastlain K., and, Johnson J., (2007) MyD88-dependent signals are essential for the host immune response in experimental brain abscess. J. Immunol. 178, 4528-4537. (Pubitemid 46492405)
-
(2007)
Journal of Immunology
, vol.178
, Issue.7
, pp. 4528-4537
-
-
Kielian, T.1
Phulwani, N.K.2
Esen, N.3
Syed, M.Md.4
Haney, A.C.5
McCastlain, K.6
Johnson, J.7
-
39
-
-
0030222037
-
Microglia: A sensor for pathological events in the CNS
-
DOI 10.1016/0166-2236(96)10049-7
-
Kreutzberg G. W., (1996) Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19, 312-318. (Pubitemid 26349059)
-
(1996)
Trends in Neurosciences
, vol.19
, Issue.8
, pp. 312-318
-
-
Kreutzberg, G.W.1
-
40
-
-
39049169762
-
A potential new pathway for Staphylococcus aureus dissemination: The silent survival of S. aureus phagocytosed by human monocyte-derived macrophages
-
e1409.
-
Kubica M., Guzik K., Koziel J., et al. (2008) A potential new pathway for Staphylococcus aureus dissemination: the silent survival of S. aureus phagocytosed by human monocyte-derived macrophages. PLoS ONE 3, e1409.
-
(2008)
PLoS ONE
, vol.3
-
-
Kubica, M.1
Guzik, K.2
Koziel, J.3
-
42
-
-
0028586052
-
Quantification of the mononuclear phagocyte response to Wallerian degeneration of the optic nerve
-
Lawson L. J., Frost L., Risbridger J., Fearn S., and, Perry V. H., (1994) Quantification of the mononuclear phagocyte response to Wallerian degeneration of the optic nerve. J. Neurocytol. 23, 729-744.
-
(1994)
J. Neurocytol.
, vol.23
, pp. 729-744
-
-
Lawson, L.J.1
Frost, L.2
Risbridger, J.3
Fearn, S.4
Perry, V.H.5
-
43
-
-
34247106805
-
Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1β and IL-18 release
-
Li H., Nookala S., and, Re F., (2007) Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release. J. Immunol. 178, 5271-5276. (Pubitemid 46595312)
-
(2007)
Journal of Immunology
, vol.178
, Issue.8
, pp. 5271-5276
-
-
Li, H.1
Nookala, S.2
Re, F.3
-
44
-
-
47849087075
-
Cutting edge: Inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3
-
Li H., Willingham S. B., Ting J. P., and, Re F., (2008) Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. J. Immunol. 181, 17-21.
-
(2008)
J. Immunol.
, vol.181
, pp. 17-21
-
-
Li, H.1
Willingham, S.B.2
Ting, J.P.3
Re, F.4
-
45
-
-
77956936562
-
P2X(7) receptor-mediated release of cathepsins from macrophages is a cytokine-independent mechanism potentially involved in joint diseases
-
Lopez-Castejon G., Theaker J., Pelegrin P., Clifton A. D., Braddock M., and, Surprenant A., (2010) P2X(7) receptor-mediated release of cathepsins from macrophages is a cytokine-independent mechanism potentially involved in joint diseases. J. Immunol. 185, 2611-2619.
-
(2010)
J. Immunol.
, vol.185
, pp. 2611-2619
-
-
Lopez-Castejon, G.1
Theaker, J.2
Pelegrin, P.3
Clifton, A.D.4
Braddock, M.5
Surprenant, A.6
-
46
-
-
34247165763
-
ASC, Ipaf and Cryopyrin/Nalp3: Bona fide intracellular adapters of the caspase-1 inflammasome
-
DOI 10.1016/j.micinf.2007.01.017, PII S1286457907000494
-
Mariathasan S., (2007) ASC, Ipaf and Cryopyrin/Nalp3: bona fide intracellular adapters of the caspase-1 inflammasome. Microbes Infect. 9, 664-671. (Pubitemid 46602026)
-
(2007)
Microbes and Infection
, vol.9
, Issue.5
, pp. 664-671
-
-
Mariathasan, S.1
-
47
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
DOI 10.1038/nature02664
-
Mariathasan S., Newton K., Monack D. M., Vucic D., French D. M., Lee W. P., Roose-Girma M., Erickson S., and, Dixit V. M., (2004) Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 430, 213-218. (Pubitemid 38902430)
-
(2004)
Nature
, vol.430
, Issue.6996
, pp. 213-218
-
-
Mariathasan, S.1
Hewton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
Roose-Girma, M.7
Erickson, S.8
Dixit, V.M.9
-
48
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
DOI 10.1038/nature04515, PII N04515
-
Mariathasan S., Weiss D. S., Newton K., McBride J., O'Rourke K., Roose-Girma M., Lee W. P., Weinrauch Y., Monack D. M., and, Dixit V. M., (2006) Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440, 228-232. (Pubitemid 43372102)
-
(2006)
Nature
, vol.440
, Issue.7081
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
49
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
DOI 10.1038/nature04516, PII N04516
-
Martinon F., Petrilli V., Mayor A., Tardivel A., and, Tschopp J., (2006) Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440, 237-241. (Pubitemid 43372104)
-
(2006)
Nature
, vol.440
, Issue.7081
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
50
-
-
38649126557
-
Cathepsins are required for Toll-like receptor 9 responses
-
Matsumoto F., Saitoh S., Fukui R., Kobayashi T., Tanimura N., Konno K., Kusumoto Y., Akashi-Takamura S., and, Miyake K., (2008) Cathepsins are required for Toll-like receptor 9 responses. Biochem. Biophys. Res. Commun. 367, 693-699.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.367
, pp. 693-699
-
-
Matsumoto, F.1
Saitoh, S.2
Fukui, R.3
Kobayashi, T.4
Tanimura, N.5
Konno, K.6
Kusumoto, Y.7
Akashi-Takamura, S.8
Miyake, K.9
-
51
-
-
0029556445
-
Bacterial hemolysins and leukotoxins affect target cells by forming large exogenous pores into their plasma membrane. Escherichia coli hemolysin A as a case example
-
DOI 10.1007/BF01204356
-
Menestrina G., Dalla Serra M., Pederzolli C., Bregante M., and, Gambale F., (1995) Bacterial hemolysins and leukotoxins affect target cells by forming large exogenous pores into their plasma membrane: Escherichia coli hemolysin A as a case example. Biosci. Rep. 15, 543-551. (Pubitemid 26153987)
-
(1995)
Bioscience Reports
, vol.15
, Issue.6
, pp. 543-551
-
-
Menestrina, G.1
Dalla Serra, M.2
Pederzolli, C.3
Bregante, M.4
Gambale, F.5
-
52
-
-
0042335651
-
Ion channels and bacterial infection: The case of β-barrel pore-forming protein toxins of Staphylococcus aureus
-
DOI 10.1016/S0014-5793(03)00850-0
-
Menestrina G., Dalla Serra M., Comai M., Coraiola M., Viero G., Werner S., Colin D. A., Monteil H., and, Prevost G., (2003) Ion channels and bacterial infection: the case of beta-barrel pore-forming protein toxins of Staphylococcus aureus. FEBS Lett. 552, 54-60. (Pubitemid 37103009)
-
(2003)
FEBS Letters
, vol.552
, Issue.1
, pp. 54-60
-
-
Menestrina, G.1
Dalla Serra, M.2
Comai, M.3
Coraiola, M.4
Viero, G.5
Werner, S.6
Colin, D.A.7
Monteil, H.8
Prevost, G.9
-
53
-
-
38449116707
-
Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo
-
Miller L. S., Pietras E. M., Uricchio L. H., et al. (2007) Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo. J. Immunol. 179, 6933-6942.
-
(2007)
J. Immunol.
, vol.179
, pp. 6933-6942
-
-
Miller, L.S.1
Pietras, E.M.2
Uricchio, L.H.3
-
54
-
-
0037242676
-
Purification, cloning and characterization of variant LukE-LukD with strong leukocidal activity of staphylococcal bi-component leukotoxin family
-
Morinaga N., Kaihou Y., and, Noda M., (2003) Purification, cloning and characterization of variant LukE-LukD with strong leukocidal activity of staphylococcal bi-component leukotoxin family. Microbiol. Immunol. 47, 81-90. (Pubitemid 36119655)
-
(2003)
Microbiology and Immunology
, vol.47
, Issue.1
, pp. 81-90
-
-
Morinaga, N.1
Kaihou, Y.2
Noda, M.3
-
55
-
-
70349334298
-
A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome
-
Munoz-Planillo R., Franchi L., Miller L. S., and, Nunez G., (2009) A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome. J. Immunol. 183, 3942-3948.
-
(2009)
J. Immunol.
, vol.183
, pp. 3942-3948
-
-
Munoz-Planillo, R.1
Franchi, L.2
Miller, L.S.3
Nunez, G.4
-
56
-
-
69049106468
-
Central nervous system invasion by community-acquired meticillin-resistant Staphylococcus aureus
-
Naesens R., Ronsyn M., Druwe P., Denis O., Ieven M., and, Jeurissen A., (2009) Central nervous system invasion by community-acquired meticillin-resistant Staphylococcus aureus. J. Med. Microbiol. 58, 1247-1251.
-
(2009)
J. Med. Microbiol.
, vol.58
, pp. 1247-1251
-
-
Naesens, R.1
Ronsyn, M.2
Druwe, P.3
Denis, O.4
Ieven, M.5
Jeurissen, A.6
-
57
-
-
64049084303
-
Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages
-
Netea M. G., Nold-Petry C. A., Nold M. F., et al. (2009) Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages. Blood 113, 2324-2335.
-
(2009)
Blood
, vol.113
, pp. 2324-2335
-
-
Netea, M.G.1
Nold-Petry, C.A.2
Nold, M.F.3
-
58
-
-
77649241827
-
IL-1beta processing in host defense: Beyond the inflammasomes
-
e1000661.
-
Netea M. G., Simon A., van de Veerdonk F., Kullberg B. J., Van der Meer J. W., and, Joosten L. A., (2010) IL-1beta processing in host defense: beyond the inflammasomes. PLoS Pathog. 6, e1000661.
-
(2010)
PLoS Pathog.
, vol.6
-
-
Netea, M.G.1
Simon, A.2
Van De Veerdonk, F.3
Kullberg, B.J.4
Van Der Meer, J.W.5
Joosten, L.A.6
-
59
-
-
0345294457
-
A revised view of the central nervous system microenvironment and major histocompatibility complex class II antigen presentation
-
Perry V. H., (1998) A revised view of the central nervous system microenvironment and major histocompatibility complex class II antigen presentation. J. Neuroimmunol. 90, 113-121.
-
(1998)
J. Neuroimmunol.
, vol.90
, pp. 113-121
-
-
Perry, V.H.1
-
60
-
-
0023893302
-
Macrophages and microglia in the nervous system
-
Perry V. H., and, Gordon S., (1988) Macrophages and microglia in the nervous system. Trends Neurosci. 11, 273-277.
-
(1988)
Trends Neurosci.
, vol.11
, pp. 273-277
-
-
Perry, V.H.1
Gordon, S.2
-
61
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
DOI 10.1038/sj.cdd.4402195, PII 4402195
-
Petrilli V., Papin S., Dostert C., Mayor A., Martinon F., and, Tschopp J., (2007) Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ. 14, 1583-1589. (Pubitemid 47278844)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.9
, pp. 1583-1589
-
-
Petrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
62
-
-
55749105944
-
TLR2 expression in astrocytes is induced by TNF-alpha- and NF-kappa B-dependent pathways
-
Phulwani N. K., Esen N., Syed M. M., and, Kielian T., (2008) TLR2 expression in astrocytes is induced by TNF-alpha- and NF-kappa B-dependent pathways. J. Immunol. 181, 3841-3849.
-
(2008)
J. Immunol.
, vol.181
, pp. 3841-3849
-
-
Phulwani, N.K.1
Esen, N.2
Syed, M.M.3
Kielian, T.4
-
63
-
-
34548614009
-
Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages
-
Qu Y., Franchi L., Nunez G., and, Dubyak G. R., (2007) Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages. J. Immunol. 179, 1913-1925.
-
(2007)
J. Immunol.
, vol.179
, pp. 1913-1925
-
-
Qu, Y.1
Franchi, L.2
Nunez, G.3
Dubyak, G.R.4
-
64
-
-
77955356552
-
Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: A novel link between cholesterol metabolism and inflammation
-
e11765.
-
Rajamaki K., Lappalainen J., Oorni K., Valimaki E., Matikainen S., Kovanen P. T., and, Eklund K. K., (2010) Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation. PLoS ONE 5, e11765.
-
(2010)
PLoS ONE
, vol.5
-
-
Rajamaki, K.1
Lappalainen, J.2
Oorni, K.3
Valimaki, E.4
Matikainen, S.5
Kovanen, P.T.6
Eklund, K.K.7
-
65
-
-
77950362382
-
The inflammasomes
-
Schroder K., and, Tschopp J., (2010) The inflammasomes. Cell 140, 821-832.
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
66
-
-
74049087445
-
Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion
-
Shimada T., Park B. G., Wolf A. J., et al. (2010) Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion. Cell Host Microbe 7, 38-49.
-
(2010)
Cell Host Microbe
, vol.7
, pp. 38-49
-
-
Shimada, T.1
Park, B.G.2
Wolf, A.J.3
-
67
-
-
35348814290
-
Fatal brain abscess due to community-associated methicillin-resistant Staphylococcus aureus strain USA300
-
DOI 10.1086/522171
-
Sifri C. D., Park J., Helm G. A., Stemper M. E., and, Shukla S. K., (2007) Fatal brain abscess due to community-associated methicillin-resistant Staphylococcus aureus strain USA300. Clin. Infect. Dis. 45, e113-117. (Pubitemid 47580338)
-
(2007)
Clinical Infectious Diseases
, vol.45
, Issue.9
-
-
Sifri, C.D.1
Park, J.2
Helm, G.A.3
Stemper, M.E.4
Shukla, S.K.5
-
68
-
-
0032055756
-
2+ channels in the membrane of human polymorphonuclear neutrophils
-
DOI 10.1007/s002329900358
-
Staali L., Monteil H., and, Colin D. A., (1998) The staphylococcal pore-forming leukotoxins open Ca2 + channels in the membrane of human polymorphonuclear neutrophils. J. Membr. Biol. 162, 209-216. (Pubitemid 28206695)
-
(1998)
Journal of Membrane Biology
, vol.162
, Issue.3
, pp. 209-216
-
-
Staali, L.1
Monteil, H.2
Colin, D.A.3
-
69
-
-
13244260877
-
An essential role for tumor necrosis factor in the formation of experimental murine Staphylococcus aureus-induced brain abscess and clearance
-
Stenzel W., Soltek S., Miletic H., Hermann M. M., Korner H., Sedgwick J. D., Schluter D., and, Deckert M., (2005a) An essential role for tumor necrosis factor in the formation of experimental murine Staphylococcus aureus-induced brain abscess and clearance. J. Neuropathol. Exp. Neurol. 64, 27-36. (Pubitemid 40189476)
-
(2005)
Journal of Neuropathology and Experimental Neurology
, vol.64
, Issue.1
, pp. 27-36
-
-
Stenzel, W.1
Soltek, S.2
Miletic, H.3
Hermann, M.M.4
Korner, H.5
Sedgwick, J.D.6
Schluter, D.7
Deckert, M.8
-
70
-
-
33644790939
-
Regulation of the inflammatory response to Staphylococcus aureus-induced brain abscess by interleukin-10
-
Stenzel W., Dahm J., Sanchez-Ruiz M., Miletic H., Hermann M., Courts C., Schwindt H., Utermohlen O., Schluter D., and, Deckert M., (2005b) Regulation of the inflammatory response to Staphylococcus aureus-induced brain abscess by interleukin-10. J. Neuropathol. Exp. Neurol. 64, 1046-1057.
-
(2005)
J. Neuropathol. Exp. Neurol.
, vol.64
, pp. 1046-1057
-
-
Stenzel, W.1
Dahm, J.2
Sanchez-Ruiz, M.3
Miletic, H.4
Hermann, M.5
Courts, C.6
Schwindt, H.7
Utermohlen, O.8
Schluter, D.9
Deckert, M.10
-
71
-
-
32544448639
-
2+ signaling
-
DOI 10.1523/JNEUROSCI.3902-05.2006
-
Suadicani S. O., Brosnan C. F., and, Scemes E., (2006) P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2 + signaling. J. Neurosci. 26, 1378-1385. (Pubitemid 43237008)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.5
, pp. 1378-1385
-
-
Suadicani, S.O.1
Brosnan, C.F.2
Scemes, E.3
-
72
-
-
73349135899
-
Involvement of cathepsin B in the processing and secretion of interleukin-1beta in chromogranin A-stimulated microglia
-
Terada K., Yamada J., Hayashi Y., Wu Z., Uchiyama Y., Peters C., and, Nakanishi H., (2010) Involvement of cathepsin B in the processing and secretion of interleukin-1beta in chromogranin A-stimulated microglia. Glia 58, 114-124.
-
(2010)
Glia
, vol.58
, pp. 114-124
-
-
Terada, K.1
Yamada, J.2
Hayashi, Y.3
Wu, Z.4
Uchiyama, Y.5
Peters, C.6
Nakanishi, H.7
-
73
-
-
58149459143
-
Developmental regulation of TREM2 and DAP12 expression in the murine CNS: Implications for Nasu-Hakola disease
-
Thrash J. C., Torbett B. E., and, Carson M. J., (2009) Developmental regulation of TREM2 and DAP12 expression in the murine CNS: implications for Nasu-Hakola disease. Neurochem. Res. 34, 38-45.
-
(2009)
Neurochem. Res.
, vol.34
, pp. 38-45
-
-
Thrash, J.C.1
Torbett, B.E.2
Carson, M.J.3
-
74
-
-
0031608167
-
Infections of the central nervous system
-
Townsend G. C., and, Scheld W. M., (1998) Infections of the central nervous system. Adv. Intern. Med. 43, 403-447.
-
(1998)
Adv. Intern. Med.
, vol.43
, pp. 403-447
-
-
Townsend, G.C.1
Scheld, W.M.2
-
75
-
-
77649179433
-
NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?
-
Tschopp J., and, Schroder K., (2010) NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? Nat. Rev. Immunol. 10, 210-215.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 210-215
-
-
Tschopp, J.1
Schroder, K.2
-
76
-
-
77955399259
-
Identification of a novel Staphylococcus aureus two-component leukotoxin using cell surface proteomics
-
e11634.
-
Ventura C. L., Malachowa N., Hammer C. H., Nardone G. A., Robinson M. A., Kobayashi S. D., and, DeLeo F. R., (2010) Identification of a novel Staphylococcus aureus two-component leukotoxin using cell surface proteomics. PLoS ONE 5, e11634.
-
(2010)
PLoS ONE
, vol.5
-
-
Ventura, C.L.1
Malachowa, N.2
Hammer, C.H.3
Nardone, G.A.4
Robinson, M.A.5
Kobayashi, S.D.6
Deleo, F.R.7
-
77
-
-
0029954974
-
Autocrine signaling through ATP release represents a novel mechanism for cell volume regulation
-
DOI 10.1073/pnas.93.21.12020
-
Wang Y., Roman R., Lidofsky S. D., and, Fitz J. G., (1996) Autocrine signaling through ATP release represents a novel mechanism for cell volume regulation. Proc. Natl. Acad. Sci. USA 93, 12020-12025. (Pubitemid 26347241)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.21
, pp. 12020-12025
-
-
Wang, Y.1
Roman, R.2
Lidofsky, S.D.3
Fitz, J.G.4
-
78
-
-
34247095700
-
TLR2-mediated survival of Staphylococcus aureus in macrophages: A novel bacterial strategy against host innate immunity
-
Watanabe I., Ichiki M., Shiratsuchi A., and, Nakanishi Y., (2007) TLR2-mediated survival of Staphylococcus aureus in macrophages: a novel bacterial strategy against host innate immunity. J. Immunol. 178, 4917-4925. (Pubitemid 46595274)
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(2007)
Journal of Immunology
, vol.178
, Issue.8
, pp. 4917-4925
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Watanabe, I.1
Ichiki, M.2
Shiratsuchi, A.3
Nakanishi, Y.4
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