Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 48, 2014, Pages 17254-17259

  Guey, Baptiste ^a,b,c   Bodnar, Mélanie ^a,b,c   Manié, Serge N ^a,b,c   Tardivel, Aubry ^d   Petrilli, Virginie ^a,b,c  

^a CENTRE DE RECHERCHE EN CANCÉROLOGIE DE LYON   (France)

^b UNIVERSITÉ LYON 1   (France)

^c CENTRE LÉON BÉRARD   (France)

^d UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BACILLUS ANTHRACIS;

APOPTOSIS REGULATORY PROTEIN; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; NALP1B PROTEIN, MOUSE; NIGERICIN; PYCARD PROTEIN, MOUSE;

ANIMAL; APOPTOSIS; BAGG ALBINO MOUSE; BIOLOGICAL MODEL; CELL CULTURE; DENDRITIC CELL; DRUG EFFECTS; FLUORESCENCE MICROSCOPY; GENETICS; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; PERITONEUM MACROPHAGE; PROTEIN DEGRADATION; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BLOTTING, WESTERN; CARRIER PROTEINS; CASPASE 1; CELLS, CULTURED; DENDRITIC CELLS; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGES; MACROPHAGES, PERITONEAL; MICE, INBRED BALB C; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; NIGERICIN; PROTEOLYSIS;

EID: 84914132432     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1415756111     Document Type: Article

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