-
1
-
-
51949097139
-
Caspase-1 activation in macrophages infected with Yersinia pestis KIM requires the type III secretion system effector YopJ
-
Lilo S, Zheng Y, Bliska JB (2008) Caspase-1 activation in macrophages infected with Yersinia pestis KIM requires the type III secretion system effector YopJ. Infect Immun 76(9):3911-3923.
-
(2008)
Infect Immun
, vol.76
, Issue.9
, pp. 3911-3923
-
-
Lilo, S.1
Zheng, Y.2
Bliska, J.B.3
-
2
-
-
84881027178
-
Cell death programs in Yersinia immunity and pathogenesis
-
Philip NH, Brodsky IE (2012) Cell death programs in Yersinia immunity and pathogenesis. Front Cell Infect Microbiol 2:149.
-
(2012)
Front Cell Infect Microbiol
, vol.2
, pp. 149
-
-
Philip, N.H.1
Brodsky, I.E.2
-
3
-
-
27744440537
-
Pathogenesis of Yersinia pestis infection in BALB/c mice: Effects on host macrophages and neutrophils
-
Lukaszewski RA, et al. (2005) Pathogenesis of Yersinia pestis infection in BALB/c mice: Effects on host macrophages and neutrophils. Infect Immun 73(11):7142-7150.
-
(2005)
Infect Immun
, vol.73
, Issue.11
, pp. 7142-7150
-
-
Lukaszewski, R.A.1
-
4
-
-
78449269290
-
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
-
Miao EA, et al. (2010) Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria. Nat Immunol 11(12):1136-1142.
-
(2010)
Nat Immunol
, vol.11
, Issue.12
, pp. 1136-1142
-
-
Miao, E.A.1
-
5
-
-
77958184901
-
Manipulation of host cell death pathways during microbial infections
-
Lamkanfi M, Dixit VM (2010) Manipulation of host cell death pathways during microbial infections. Cell Host Microbe 8(1):44-54.
-
(2010)
Cell Host Microbe
, vol.8
, Issue.1
, pp. 44-54
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
6
-
-
84856759660
-
Many stimuli pull the necrotic trigger, an overview
-
Vanlangenakker N, Vanden Berghe T, Vandenabeele P (2012) Many stimuli pull the necrotic trigger, an overview. Cell Death Differ 19(1):75-86.
-
(2012)
Cell Death Differ
, vol.19
, Issue.1
, pp. 75-86
-
-
Vanlangenakker, N.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
7
-
-
84856231635
-
Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways
-
Mocarski ES, Upton JW, Kaiser WJ (2012) Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways. Nat Rev Immunol 12(2):79-88.
-
(2012)
Nat Rev Immunol
, vol.12
, Issue.2
, pp. 79-88
-
-
Mocarski, E.S.1
Upton, J.W.2
Kaiser, W.J.3
-
8
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
Oberst A, et al. (2011) Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 471(7338):363-367.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 363-367
-
-
Oberst, A.1
-
9
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser WJ, et al. (2011) RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 471(7338):368-372.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 368-372
-
-
Kaiser, W.J.1
-
10
-
-
20044368626
-
Requirement for caspase-8 in NF-kappaB activation by antigen receptor
-
Su H, et al. (2005) Requirement for caspase-8 in NF-kappaB activation by antigen receptor. Science 307(5714):1465-1468.
-
(2005)
Science
, vol.307
, Issue.5714
, pp. 1465-1468
-
-
Su, H.1
-
11
-
-
34848886878
-
Catalytically active Yersinia outer protein P induces cleavage of RIP and caspase-8 at the level of the DISC independently of death receptors in dendritic cells
-
Grbner S, et al. (2007) Catalytically active Yersinia outer protein P induces cleavage of RIP and caspase-8 at the level of the DISC independently of death receptors in dendritic cells. Apoptosis 12(10):1813-1825.
-
(2007)
Apoptosis
, vol.12
, Issue.10
, pp. 1813-1825
-
-
Grbner, S.1
-
12
-
-
84860354862
-
YopJ-induced caspase-1 activation in Yersinia- infected macrophages: Independent of apoptosis, linked to necrosis, dispensable for innate host defense
-
Zheng Y, Lilo S, Mena P, Bliska JB (2012) YopJ-induced caspase-1 activation in Yersinia- infected macrophages: Independent of apoptosis, linked to necrosis, dispensable for innate host defense. PLoS ONE 7(4):e36019.
-
(2012)
PLoS ONE
, vol.7
, Issue.4
-
-
Zheng, Y.1
Lilo, S.2
Mena, P.3
Bliska, J.B.4
-
13
-
-
0031744367
-
Yersinia-induced apoptosis in vivo aids in the establishment of a systemic infection of mice
-
Monack DM, Mecsas J, Bouley D, Falkow S (1998) Yersinia-induced apoptosis in vivo aids in the establishment of a systemic infection of mice. J Exp Med 188(11): 2127-2137.
-
(1998)
J Exp Med
, vol.188
, Issue.11
, pp. 2127-2137
-
-
Monack, D.M.1
Mecsas, J.2
Bouley, D.3
Falkow, S.4
-
14
-
-
77951221762
-
YopJ-promoted cytotoxicity and systemic colonization are associated with high levels of murine interleukin-18, gamma interferon, and neutrophils in a live vaccine model of Yersinia pseudotuberculosis infection
-
Zhang Y, Bliska JB (2010) YopJ-promoted cytotoxicity and systemic colonization are associated with high levels of murine interleukin-18, gamma interferon, and neutrophils in a live vaccine model of Yersinia pseudotuberculosis infection. Infect Immun 78(5):2329-2341.
-
(2010)
Infect Immun
, vol.78
, Issue.5
, pp. 2329-2341
-
-
Zhang, Y.1
Bliska, J.B.2
-
15
-
-
44949187452
-
Reduced secretion of YopJ by Yersinia limits in vivo cell death but enhances bacterial virulence
-
Brodsky IE, Medzhitov R (2008) Reduced secretion of YopJ by Yersinia limits in vivo cell death but enhances bacterial virulence. PLoS Pathog 4(5):e1000067.
-
(2008)
PLoS Pathog
, vol.4
, Issue.5
-
-
Brodsky, I.E.1
Medzhitov, R.2
-
16
-
-
77953562208
-
A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system
-
Brodsky IE, et al. (2010) A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system. Cell Host Microbe 7(5): 376-387.
-
(2010)
Cell Host Microbe
, vol.7
, Issue.5
, pp. 376-387
-
-
Brodsky, I.E.1
-
17
-
-
33744457909
-
Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation
-
Mukherjee S, et al. (2006) Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation. Science 312(5777):1211-1214.
-
(2006)
Science
, vol.312
, Issue.5777
, pp. 1211-1214
-
-
Mukherjee, S.1
-
18
-
-
33845480946
-
Acetylation of MEK2 and i kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling
-
Mittal R, Peak-Chew SY, McMahon HT (2006) Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling. Proc Natl Acad Sci USA 103(49):18574-18579.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.49
, pp. 18574-18579
-
-
Mittal, R.1
Peak-Chew, S.Y.2
McMahon, H.T.3
-
19
-
-
84864518388
-
Serine/threonine acetylation of TGFβ-Activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling
-
Paquette N, et al. (2012) Serine/threonine acetylation of TGFβ-Activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling. Proc Natl Acad Sci USA 109(31):12710-12715.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.31
, pp. 12710-12715
-
-
Paquette, N.1
-
20
-
-
84860001887
-
Yersinia pseudotuberculosis effector YopJ subverts the Nod2/ RICK/TAK1 pathway and activates caspase-1 to induce intestinal barrier dysfunction
-
Meinzer U, et al. (2012) Yersinia pseudotuberculosis effector YopJ subverts the Nod2/ RICK/TAK1 pathway and activates caspase-1 to induce intestinal barrier dysfunction. Cell Host Microbe 11(4):337-351.
-
(2012)
Cell Host Microbe
, vol.11
, Issue.4
, pp. 337-351
-
-
Meinzer, U.1
-
21
-
-
34548225362
-
NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta
-
Greten FR, et al. (2007) NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell 130(5):918-931.
-
(2007)
Cell
, vol.130
, Issue.5
, pp. 918-931
-
-
Greten, F.R.1
-
22
-
-
84875813739
-
Inflammasomes and host defenses against bacterial infections
-
Vladimer GI, Marty-Roix R, Ghosh S, Weng D, Lien E (2013) Inflammasomes and host defenses against bacterial infections. Curr Opin Microbiol 16(1):23-31.
-
(2013)
Curr Opin Microbiol
, vol.16
, Issue.1
, pp. 23-31
-
-
Vladimer, G.I.1
Marty-Roix, R.2
Ghosh, S.3
Weng, D.4
Lien, E.5
-
23
-
-
79955776183
-
A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages
-
Zheng Y, et al. (2011) A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages. PLoS Pathog 7(4):e1002026.
-
(2011)
PLoS Pathog
, vol.7
, Issue.4
-
-
Zheng, Y.1
-
24
-
-
33748875900
-
Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response
-
Montminy SW, et al. (2006) Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response. Nat Immunol 7(10):1066-1073.
-
(2006)
Nat Immunol
, vol.7
, Issue.10
, pp. 1066-1073
-
-
Montminy, S.W.1
-
25
-
-
84864317101
-
The NLRP12 inflammasome recognizes Yersinia pestis
-
Vladimer GI, et al. (2012) The NLRP12 inflammasome recognizes Yersinia pestis. Immunity 37(1):96-107.
-
(2012)
Immunity
, vol.37
, Issue.1
, pp. 96-107
-
-
Vladimer, G.I.1
-
26
-
-
80054888589
-
It cuts both ways: Reconciling the dual roles of caspase 8 in cell death and survival
-
Oberst A, Green DR (2011) It cuts both ways: Reconciling the dual roles of caspase 8 in cell death and survival. Nat Rev Mol Cell Biol 12(11):757-763.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, Issue.11
, pp. 757-763
-
-
Oberst, A.1
Green, D.R.2
-
27
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho YS, et al. (2009) Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137(6):1112-1123.
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1112-1123
-
-
Cho, Y.S.1
-
28
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNFinduced cell death from apoptosis to necrosis
-
Zhang DW, et al. (2009) RIP3, an energy metabolism regulator that switches TNFinduced cell death from apoptosis to necrosis. Science 325(5938):332-336.
-
(2009)
Science
, vol.325
, Issue.5938
, pp. 332-336
-
-
Zhang, D.W.1
-
29
-
-
77955271788
-
The molecular regulation of programmed necrotic cell injury
-
Moquin D, Chan FK (2010) The molecular regulation of programmed necrotic cell injury. Trends Biochem Sci 35(8):434-441.
-
(2010)
Trends Biochem Sci
, vol.35
, Issue.8
, pp. 434-441
-
-
Moquin, D.1
Chan, F.K.2
-
30
-
-
27744561393
-
Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-kappaB activation but does not contribute to interferon regulatory factor 3 activation
-
Cusson-Hermance N, Khurana S, Lee TH, Fitzgerald KA, Kelliher MA (2005) Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-kappaB activation but does not contribute to interferon regulatory factor 3 activation. J Biol Chem 280(44):36560-36566.
-
(2005)
J Biol Chem
, vol.280
, Issue.44
, pp. 36560-36566
-
-
Cusson-Hermance, N.1
Khurana, S.2
Lee, T.H.3
Fitzgerald, K.A.4
Kelliher, M.A.5
-
31
-
-
0032033132
-
The death domain kinase RIP mediates the TNF-induced NF-kappaB signal
-
Kelliher MA, et al. (1998) The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. Immunity 8(3):297-303.
-
(1998)
Immunity
, vol.8
, Issue.3
, pp. 297-303
-
-
Kelliher, M.A.1
-
32
-
-
84886656964
-
Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL
-
Kaiser WJ, et al. (2013) Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL. J Biol Chem 288(43):31268-31279.
-
(2013)
J Biol Chem
, vol.288
, Issue.43
, pp. 31268-31279
-
-
Kaiser, W.J.1
-
33
-
-
33845991525
-
Absence of Toll-like receptor 4 signaling results in delayed Yersinia enterocolitica YopP-induced cell death of dendritic cells
-
Grbner S, et al. (2007) Absence of Toll-like receptor 4 signaling results in delayed Yersinia enterocolitica YopP-induced cell death of dendritic cells. Infect Immun 75(1): 512-517.
-
(2007)
Infect Immun
, vol.75
, Issue.1
, pp. 512-517
-
-
Grbner, S.1
-
34
-
-
0037372795
-
Role of Toll-like receptor signaling in the apoptotic response of macrophages to Yersinia infection
-
Zhang Y, Bliska JB (2003) Role of Toll-like receptor signaling in the apoptotic response of macrophages to Yersinia infection. Infect Immun 71(3):1513-1519.
-
(2003)
Infect Immun
, vol.71
, Issue.3
, pp. 1513-1519
-
-
Zhang, Y.1
Bliska, J.B.2
-
35
-
-
0141923688
-
A dominant role of Toll-like receptor 4 in the signaling of apoptosis in bacteria-faced macrophages
-
Haase R, et al. (2003) A dominant role of Toll-like receptor 4 in the signaling of apoptosis in bacteria-faced macrophages. J Immunol 171(8):4294-4303.
-
(2003)
J Immunol
, vol.171
, Issue.8
, pp. 4294-4303
-
-
Haase, R.1
-
36
-
-
4344560197
-
Caspase-8 serves both apoptotic and nonapoptotic roles
-
Kang TB, et al. (2004) Caspase-8 serves both apoptotic and nonapoptotic roles. J Immunol 173(5):2976-2984.
-
(2004)
J Immunol
, vol.173
, Issue.5
, pp. 2976-2984
-
-
Kang, T.B.1
-
37
-
-
79960922705
-
CIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms
-
Feoktistova M, et al. (2011) cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Mol Cell 43(3):449-463.
-
(2011)
Mol Cell
, vol.43
, Issue.3
, pp. 449-463
-
-
Feoktistova, M.1
-
38
-
-
84887439544
-
Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1β production
-
Man SM, et al. (2013) Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1β production. J Immunol 191(10):5239-5246.
-
(2013)
J Immunol
, vol.191
, Issue.10
, pp. 5239-5246
-
-
Man, S.M.1
-
39
-
-
52149095957
-
Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosometransgenic mice
-
Kang TB, et al. (2008) Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosometransgenic mice. J Immunol 181(4):2522-2532.
-
(2008)
J Immunol
, vol.181
, Issue.4
, pp. 2522-2532
-
-
Kang, T.B.1
-
40
-
-
84872764927
-
Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome
-
Kang TB, Yang SH, Toth B, Kovalenko A, Wallach D (2013) Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity 38(1):27-40.
-
(2013)
Immunity
, vol.38
, Issue.1
, pp. 27-40
-
-
Kang, T.B.1
Yang, S.H.2
Toth, B.3
Kovalenko, A.4
Wallach, D.5
-
41
-
-
84857404572
-
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation
-
Vince JE, et al. (2012) Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation. Immunity 36(2):215-227.
-
(2012)
Immunity
, vol.36
, Issue.2
, pp. 215-227
-
-
Vince, J.E.1
-
42
-
-
84871125002
-
Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL- 18 maturation via caspase-8 in an RIP3-independent manner
-
Bossaller L, et al. (2012) Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL- 18 maturation via caspase-8 in an RIP3-independent manner. J Immunol 189(12): 5508-5512.
-
(2012)
J Immunol
, vol.189
, Issue.12
, pp. 5508-5512
-
-
Bossaller, L.1
-
43
-
-
84857175933
-
Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome
-
Gringhuis SI, et al. (2012) Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome. Nat Immunol 13(3):246-254.
-
(2012)
Nat Immunol
, vol.13
, Issue.3
, pp. 246-254
-
-
Gringhuis, S.I.1
-
44
-
-
51049100571
-
Stimulation of Toll-like receptor 3 and 4 induces interleukin- 1beta maturation by caspase-8
-
Maelfait J, et al. (2008) Stimulation of Toll-like receptor 3 and 4 induces interleukin- 1beta maturation by caspase-8. J Exp Med 205(9):1967-1973.
-
(2008)
J Exp Med
, vol.205
, Issue.9
, pp. 1967-1973
-
-
Maelfait, J.1
-
45
-
-
84885966098
-
Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells
-
Antonopoulos C, El Sanadi C, Kaiser WJ, Mocarski ES, Dubyak GR (2013) Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells. J Immunol 191(9):4789-4803.
-
(2013)
J Immunol
, vol.191
, Issue.9
, pp. 4789-4803
-
-
Antonopoulos, C.1
El Sanadi, C.2
Kaiser, W.J.3
Mocarski, E.S.4
Dubyak, G.R.5
-
46
-
-
84894271641
-
FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes
-
Gurung P, et al. (2014) FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes. J Immunol 192(4):1835-1846.
-
(2014)
J Immunol
, vol.192
, Issue.4
, pp. 1835-1846
-
-
Gurung, P.1
-
47
-
-
84896500701
-
Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1β in response to TLR4 stimulation through a caspase- 8- and TRIF-dependent pathway
-
Shenderov K, et al. (2014) Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1β in response to TLR4 stimulation through a caspase- 8- and TRIF-dependent pathway. J Immunol 192(5):2029-2033.
-
(2014)
J Immunol
, vol.192
, Issue.5
, pp. 2029-2033
-
-
Shenderov, K.1
-
48
-
-
84866087868
-
AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella- infected caspase-1-deficient macrophages
-
Pierini R, et al. (2012) AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella- infected caspase-1-deficient macrophages. Cell Death Differ 19(10):1709-1721.
-
(2012)
Cell Death Differ
, vol.19
, Issue.10
, pp. 1709-1721
-
-
Pierini, R.1
-
49
-
-
0842304221
-
Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Tolllike receptors 2 and 4
-
Newton K, Sun X, Dixit VM (2004) Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Tolllike receptors 2 and 4. Mol Cell Biol 24(4):1464-1469.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.4
, pp. 1464-1469
-
-
Newton, K.1
Sun, X.2
Dixit, V.M.3
|