Anthrax lethal factor inhibition

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 22, 2005, Pages 7958-7963

  Shoop, W L ^a   Xiong, Y ^a   Wiltsie, J ^a   Woods, A ^a   Guo, J ^a   Pivnichny, J V ^a   Felcetto, T ^a   Michael, B F ^a   Bansal, A ^a   Cummings, R T ^a   Cunningham, B R ^a   Friedlander, A M ^b   Douglas, C M ^a   Patel, S B ^a   Wisniewski, D ^a   Scapin, G ^a   Salowe, S P ^a   Zaller, D M ^a   Chapman, K T ^a   Scolnick, E M ^c   Schmatz, D M ^a   Bartizal, K ^a   MacCoss, M ^a   Hermes, J D ^a   more..

^a MERCK RESEARCH LABORATORIES   (United States)

^b UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Bacillus anthracis; Hydroxamate

Indexed keywords

2 [(4 FLUORO 3 METHYLPHENYL)SULFONYLAMINO] N HYDROXY 2 (TETRAHYDRO 2H PYRAN 4 YL)ACETAMIDE; ANTHRAX TOXIN; ANTIGEN; CIPROFLOXACIN; HYDROXAMIC ACID; METALLOPROTEINASE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR; ZINC;

AMES TEST; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTHRAX; ARTICLE; BACILLUS ANTHRACIS; CELL DESTRUCTION; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; LETHAL GENE; MACROPHAGE; MOLECULAR INTERACTION; MONOTHERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RABBIT; SHOCK; SIGNAL TRANSDUCTION; TOXEMIA;

ANIMALS; ANTHRAX; ANTIGENS, BACTERIAL; BACILLUS ANTHRACIS; BACTERIAL TOXINS; CIPROFLOXACIN; CRYSTALLOGRAPHY; CYTOTOXICITY TESTS, IMMUNOLOGIC; DNA PRIMERS; DRUG THERAPY, COMBINATION; HYDROXAMIC ACIDS; MACROPHAGES; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; RABBITS;

BACILLUS ANTHRACIS; ORYCTOLAGUS CUNICULUS;

EID: 20344391159     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0502159102     Document Type: Article

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