Enterohemorrhagic Escherichia coli Specific Enterohemolysin Induced IL-1β in Human Macrophages and EHEC-Induced IL-1β Required Activation of NLRP3 Inflammasome

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Zhang, Xiaoai ^a   Cheng, Yuli ^a   Xiong, Yanwen ^a   Ye, Changyun ^a   Zheng, Han ^a   Sun, Hui ^a   Zhao, Hongqing ^a   Ren, Zhihong ^a   Xu, Jianguo ^a  

^a CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; ENTEROHEMOLYSIN; HEMOLYSIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LACTATE DEHYDROGENASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BACTERIAL VIRULENCE; CELL DEATH; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; ENTEROHEMORRHAGIC ESCHERICHIA COLI; ENZYME ACTIVATION; ENZYME RELEASE; ESCHERICHIA COLI O157; GENE DELETION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOGENICITY; MACROPHAGE; MUTAGENESIS; NONHUMAN; OPEN READING FRAME; PROTEIN SYNTHESIS; RNA INTERFERENCE; TRANSPOSON;

CARRIER PROTEINS; CASPASE 1; CELL LINE; CYTOKINES; ENTEROHEMORRHAGIC ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE DELETION; HEMOLYSIN PROTEINS; HUMANS; INFLAMMATION; INTERLEUKIN-1BETA; L-LACTATE DEHYDROGENASE; MACROPHAGES; MODELS, BIOLOGICAL; MONOCYTES; MUTATION; PLASMIDS; RNA INTERFERENCE; RNA, MESSENGER; TIME FACTORS; VIRULENCE;

ESCHERICHIA COLI;

EID: 84870258151     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050288     Document Type: Article

References (41)

1. Nataro JP, Kaper JB, (1998) Diarrheagenic Escherichia coli. Clin Microbiol Rev 11: 142-201.
2. Poirier K, Faucher SP, Beland M, Brousseau R, Gannon V, et al. (2008) Escherichia coli O157:H7 survives within human macrophages: global gene expression profile and involvement of the Shiga toxins. Infect Immun 76: 4814-4822.
3. van de Kar NC, Monnens LA, Karmali MA, van Hinsbergh VW, (1992) Tumor necrosis factor and interleukin-1 induce expression of the verocytotoxin receptor globotriaosylceramide on human endothelial cells: implications for the pathogenesis of the hemolytic uremic syndrome. Blood 80: 2755-2764.
4. Yamasaki C, Natori Y, Zeng XT, Ohmura M, Yamasaki S, et al. (1999) Induction of cytokines in a human colon epithelial cell line by Shiga toxin 1 (Stx1) and Stx2 but not by non-toxic mutant Stx1 which lacks N-glycosidase activity. FEBS Lett 442: 231-234.
5. Rogers TJ, Paton AW, McColl SR, Paton JC, (2003) Enhanced CXC chemokine responses of human colonic epithelial cells to locus of enterocyte effacement-negative shiga-toxigenic Escherichia coli. Infect Immun 71: 5623-5632.
6. Berin MC, Darfeuille-Michaud A, Egan LJ, Miyamoto Y, Kagnoff MF, (2002) Role of EHEC O157:H7 virulence factors in the activation of intestinal epithelial cell NF-kappaB and MAP kinase pathways and the upregulated expression of interleukin 8. Cell Microbiol 4: 635-648.
7. Khan MA, Bouzari S, Ma C, Rosenberger CM, Bergstrom KS, et al. (2008) Flagellin-dependent and-independent inflammatory responses following infection by enteropathogenic Escherichia coli and Citrobacter rodentium. Infect Immun 76: 1410-1422.
8. Zhou X, Giron JA, Torres AG, Crawford JA, Negrete E, et al. (2003) Flagellin of enteropathogenic Escherichia coli stimulates interleukin-8 production in T84 cells. Infect Immun 71: 2120-2129.
9. Burland V, Shao Y, Perna NT, Plunkett G, Sofia HJ, et al. (1998) The complete DNA sequence and analysis of the large virulence plasmid of Escherichia coli O157:H7. Nucleic Acids Res 26: 4196-4204.
10. Schmidt H, Karch H, Beutin L, (1994) The large-sized plasmids of enterohemorrhagic Escherichia coli O157 strains encode hemolysins which are presumably members of the E. coli alpha-hemolysin family. FEMS Microbiol Lett 117: 189-196.
11. Brunder W, Schmidt H, Karch H, (1996) KatP, a novel catalase-peroxidase encoded by the large plasmid of enterohaemorrhagic Escherichia coli O157:H7. Microbiology 142 (Pt 11): 3305-3315.
12. Schmidt H, Henkel B, Karch H, (1997) A gene cluster closely related to type II secretion pathway operons of gram-negative bacteria is located on the large plasmid of enterohemorrhagic Escherichia coli O157 strains. FEMS Microbiol Lett 148: 265-272.
13. Brunder W, Schmidt H, Karch H, (1997) EspP, a novel extracellular serine protease of enterohaemorrhagic Escherichia coli O157:H7 cleaves human coagulation factor V. Mol Microbiol. 24: 767-778.
14. Tatsuno I, Horie M, Abe H, Miki T, Makino K, et al. (2001) toxB gene on pO157 of enterohemorrhagic Escherichia coli O157:H7 is required for full epithelial cell adherence phenotype. Infect Immun 69: 6660-6669.
15. Lathem WW, Grys TE, Witowski SE, Torres AG, Kaper JB, et al. (2002) StcE, a metalloprotease secreted by Escherichia coli O157:H7, specifically cleaves C1 esterase inhibitor. Mol Microbiol 45: 277-288.
16. Yoon JW, Lim JY, Park YH, Hovde CJ, (2005) Involvement of the Escherichia coli O157:H7(pO157) ecf operon and lipid A myristoyl transferase activity in bacterial survival in the bovine gastrointestinal tract and bacterial persistence in farm water troughs. Infect Immun 73: 2367-2378.
17. Puttamreddy S, Cornick NA, Minion FC, (2010) Genome-wide transposon mutagenesis reveals a role for pO157 genes in biofilm development in Escherichia coli O157:H7 EDL933. Infect Immun 78: 2377-2384.
18. Schmidt H, Beutin L, Karch H, (1995) Molecular analysis of the plasmid-encoded hemolysin of Escherichia coli O157:H7 strain EDL 933. Infect Immun 63: 1055-1061.
19. Perna NT, Plunkett G, 3rd, Burland V, Mau B, Glasner JD, et al (2001) Genome sequence of enterohaemorrhagic Escherichia coli O157:H7. Nature 409: 529-533.
20. Datsenko KA, Wanner BL, (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci U S A 97: 6640-6645.
21. Lim JY, Sheng H, Seo KS, Park YH, Hovde CJ, (2007) Characterization of an Escherichia coli O157:H7 plasmid O157 deletion mutant and its survival and persistence in cattle. Appl Environ Microbiol 73: 2037-2047.
22. Wang G, Clark CG, Rodgers FG, (2002) Detection in Escherichia coli of the genes encoding the major virulence factors, the genes defining the O157:H7 serotype, and components of the type 2 Shiga toxin family by multiplex PCR. J Clin Microbiol 40: 3613-3619.
23. Daigle F, Graham JE, Curtiss R, 3rd (2001) Identification of Salmonella typhi genes expressed within macrophages by selective capture of transcribed sequences (SCOTS). Mol Microbiol 41: 1211-1222.
24. Schmittgen TD, Livak KJ, (2008) Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 3: 1101-1108.
25. Meixenberger K, Pache F, Eitel J, Schmeck B, Hippenstiel S, et al. (2010) Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3. J Immunol 184: 922-930.
26. Fernandez-Prada C, Tall BD, Elliott SE, Hoover DL, Nataro JP, et al. (1998) Hemolysin-positive enteroaggregative and cell-detaching Escherichia coli strains cause oncosis of human monocyte-derived macrophages and apoptosis of murine J774 cells. Infect Immun 66: 3918-3924.
27. Menestrina G, Pederzolli C, Dalla Serra M, Bregante M, Gambale F, (1996) Permeability increase induced by Escherichia coli hemolysin A in human macrophages is due to the formation of ionic pores: a patch clamp characterization. J Membr Biol 149: 113-121.
28. Bauer ME, Welch RA, (1996) Characterization of an RTX toxin from enterohemorrhagic Escherichia coli O157:H7. Infect Immun 64: 167-175.
29. Aldick T, Bielaszewska M, Zhang W, Brockmeyer J, Schmidt H, et al. (2007) Hemolysin from Shiga toxin-negative Escherichia coli O26 strains injures microvascular endothelium. Microbes Infect 9: 282-290.
30. Inward CD, Varagunam M, Adu D, Milford DV, Taylor CM, (1997) Cytokines in haemolytic uraemic syndrome associated with verocytotoxin-producing Escherichia coli infection. Arch Dis Child 77: 145-147.
31. Litalien C, Proulx F, Mariscalco MM, Robitaille P, Turgeon JP, et al. (1999) Circulating inflammatory cytokine levels in hemolytic uremic syndrome. Pediatr Nephrol 13: 840-845.
32. Proulx F, Toledano B, Phan V, Clermont MJ, Mariscalco MM, et al. (2002) Circulating granulocyte colony-stimulating factor, C-X-C, and C-C chemokines in children with Escherichia coli O157:H7 associated hemolytic uremic syndrome. Pediatr Res 52: 928-934.
33. Brigotti M, Caprioli A, Tozzi AE, Tazzari PL, Ricci F, et al. (2006) Shiga toxins present in the gut and in the polymorphonuclear leukocytes circulating in the blood of children with hemolytic-uremic syndrome. J Clin Microbiol 44: 313-317.
34. Louise CB, Obrig TG, (1991) Shiga toxin-associated hemolytic-uremic syndrome: combined cytotoxic effects of Shiga toxin, interleukin-1 beta, and tumor necrosis factor alpha on human vascular endothelial cells in vitro. Infect Immun 59: 4173-4179.
35. Tanabe K, Nishimura K, Dohi S, Kozawa O, (2009) Mechanisms of interleukin-1beta-induced GDNF release from rat glioma cells. Brain Res 1274: 11-20.
36. Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, et al. (2006) Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440: 228-232.
37. Gurcel L, Abrami L, Girardin S, Tschopp J, van der Goot FG, (2006) Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell 126: 1135-1145.
38. Craven RR, Gao X, Allen IC, Gris D, Bubeck Wardenburg J, et al. (2009) Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. PLoS One 4: e7446.
39. Harder J, Franchi L, Munoz-Planillo R, Park JH, Reimer T, et al. (2009) Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor. J Immunol 183: 5823-5829.
40. Munoz-Planillo R, Franchi L, Miller LS, Nunez G, (2009) A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome. J Immunol 183: 3942-3948.
41. Eder C, (2009) Mechanisms of interleukin-1beta release. Immunobiology 214: 543-553.