RNA and beta;-hemolysin of group B streptococcus induce interleukin-1β (IL-1β) by activating NLRP3 inflammasomes in mouse macrophages

Journal of Biological Chemistry

Volumn 289, Issue 20, 2014, Pages 13701-13705

  Gupta, Rahul ^a   Ghosh, Shubhendu ^a   Monks, Brian ^a   DeOliveira, Rosane B ^a   Tzeng, Te Chen ^a   Kalantari, Parisa ^a   Nandy, Anubhab ^a   Bhattacharjee, Bornali ^a   Chan, Jennie ^a   Ferreira, Fabianno ^c   Rathinam, Vijay ^a   Sharma, Shruti ^a   Lien, Egil ^a   Silverman, Neal ^a   Fitzgerald, Katherine ^a   Firon, Arnaud ^b   Trieu Cuot, Patrick ^b   Henneke, Philipp ^d   Golenbock, Douglas T ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b INSTITUT PASTEUR   (France)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; MACROPHAGES; RNA;

CYTOKINES; CYTOLYTIC TOXIN; CYTOSOLIC; GROUP B STREPTOCOCCUS; HOST RESPONSE; HUMAN PATHOGENS; INFLAMMASOME; INTERLEUKIN-1;

CHEMICAL ACTIVATION;

BACTERIAL RNA; BETA HEMOLYSIN; CATHEPSIN; CRYOPYRIN; HEMOLYSIN; INTERLEUKIN 1BETA; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; INFLAMMASOME; NLRP3 PROTEIN, HUMAN; STREPTOCOCCAL GROUP B HEMOLYSIN;

ACIDIFICATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; LYSOSOMAL LEAKAGE; LYSOSOME; MACROPHAGE; MOUSE; NONHUMAN; PHAGOLYSOSOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN RNA BINDING; STREPTOCOCCUS AGALACTIAE; ANIMAL; BIOSYNTHESIS; CYTOLOGY; HUMAN; METABOLISM; MICROBIOLOGY; PHAGOSOME; PHYSIOLOGY; SECRETION (PROCESS);

ANIMALS; BACTERIAL PROTEINS; CARRIER PROTEINS; HEMOLYSIN PROTEINS; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; LYSOSOMES; MACROPHAGES; MICE; PHAGOSOMES; RNA, BACTERIAL; STREPTOCOCCUS AGALACTIAE;

EID: 84901020681     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C114.548982     Document Type: Article

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