-
1
-
-
70350509805
-
Intestinal mucosal barrier function in health and disease
-
Turner, J. R. Intestinal mucosal barrier function in health and disease. Nature Rev. Immunol. 9, 799-809 (2009).
-
(2009)
Nature Rev. Immunol.
, vol.9
, pp. 799-809
-
-
Turner, J.R.1
-
2
-
-
75749139748
-
Breaking the wall: Targeting of the endothelium by pathogenic bacteria
-
Lemichez, E., Lecuit, M., Nassif, X. & Bourdoulous, S. Breaking the wall: targeting of the endothelium by pathogenic bacteria. Nature Rev. Microbiol. 8, 93-104 (2010).
-
(2010)
Nature Rev. Microbiol.
, vol.8
, pp. 93-104
-
-
Lemichez, E.1
Lecuit, M.2
Nassif, X.3
Bourdoulous, S.4
-
3
-
-
70249116807
-
Actin dynamics at the leading edge: From simple machinery to complex networks
-
Insall, R. H. & Machesky, L. M. Actin dynamics at the leading edge: from simple machinery to complex networks. Dev. Cell 17, 310-322 (2009).
-
(2009)
Dev. Cell
, vol.17
, pp. 310-322
-
-
Insall, R.H.1
MacHesky, L.M.2
-
4
-
-
14744299030
-
Regulation of innate immunity by Rho GTPases
-
DOI 10.1016/j.tcb.2005.01.002
-
Bokoch, G. M. Regulation of innate immunity by Rho GTPases. Trends Cell Biol. 15, 163-171 (2005). (Pubitemid 40332539)
-
(2005)
Trends in Cell Biology
, vol.15
, Issue.3
, pp. 163-171
-
-
Bokoch, G.M.1
-
5
-
-
77649153819
-
WASP: A key immunological multitasker
-
Thrasher, A. J. & Burns, S. O. WASP: a key immunological multitasker. Nature Rev. Immunol. 10, 182-192 (2010).
-
(2010)
Nature Rev. Immunol.
, vol.10
, pp. 182-192
-
-
Thrasher, A.J.1
Burns, S.O.2
-
6
-
-
84863860582
-
The cytoskeleton coordinates the early events of B-cell activation
-
Harwood, N. E. & Batista, F. D. The cytoskeleton coordinates the early events of B-cell activation. Cold Spring Harb. Perspect. Biol. 3, a002360 (2010).
-
(2010)
Cold Spring Harb. Perspect. Biol.
, vol.3
-
-
Harwood, N.E.1
Batista, F.D.2
-
8
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
Hall, A. Rho GTPases and the actin cytoskeleton. Science 279, 509-514 (1998).
-
(1998)
Science
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
10
-
-
0842281652
-
Rho and rac take center stage
-
DOI 10.1016/S0092-8674(04)00003-0
-
Burridge, K. & Wennerberg, K. Rho and Rac take center stage. Cell 116, 167-179 (2004). (Pubitemid 38167310)
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 167-179
-
-
Burridge, K.1
Wennerberg, K.2
-
11
-
-
13444252631
-
GEF means go: Turning on Rho GTPases with guanine nucleotide-exchange factors
-
DOI 10.1038/nrm1587
-
Rossman, K. L., Der, C. J. & Sondek, J. GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nature Rev. Mol. Cell Biol. 6, 167-180 (2005). (Pubitemid 40215811)
-
(2005)
Nature Reviews Molecular Cell Biology
, vol.6
, Issue.2
, pp. 167-180
-
-
Rossman, K.L.1
Der, C.J.2
Sondek, J.3
-
12
-
-
0031970317
-
Membrane association and targeting of prenylated Ras-like GTPases
-
DOI 10.1016/S0898-6568(97)00120-4, PII S0898656897001204
-
Seabra, M. C. Membrane association and targeting of prenylated Ras-like GTPases. Cell. Signal. 10, 167-172 (1998). (Pubitemid 28156067)
-
(1998)
Cellular Signalling
, vol.10
, Issue.3
, pp. 167-172
-
-
Seabra, M.C.1
-
13
-
-
33846969965
-
Current knowledge of the large RhoGAP family of proteins
-
DOI 10.1042/BC20060086
-
Tcherkezian, J. & Lamarche-Vane, N. Current knowledge of the large RhoGAP family of proteins. Biol. Cell 99, 67-86 (2007). (Pubitemid 46242033)
-
(2007)
Biology of the Cell
, vol.99
, Issue.2
, pp. 67-86
-
-
Tcherkezian, J.1
Lamarche-Vane, N.2
-
14
-
-
21744432683
-
GDIs: Central regulatory molecules in Rho GTPase activation
-
DOI 10.1016/j.tcb.2005.05.001, PII S0962892405001273
-
DerMardirossian, C. & Bokoch, G. M. GDIs: central regulatory molecules in Rho GTPase activation. Trends Cell Biol. 15, 356-363 (2005). (Pubitemid 40943524)
-
(2005)
Trends in Cell Biology
, vol.15
, Issue.7
, pp. 356-363
-
-
DerMardirossian, C.1
Bokoch, G.M.2
-
15
-
-
0024584734
-
The rho gene product expressed in E. coli is a substate of botulinum ADP-ribosyltransferase C3
-
DOI 10.1016/S0006-291X(89)80199-8
-
Aktories, K., Braun, U., Rösener, S., Just, I. & Hall, A. The rho gene product expressed in E. coli is a substrate of botulinum ADP-ribosyltransferase C3. Biochem. Biophys. Res. Commun. 158, 209-213 (1989). (Pubitemid 19045066)
-
(1989)
Biochemical and Biophysical Research Communications
, vol.158
, Issue.1
, pp. 209-213
-
-
Aktories, K.1
Braun, U.2
Rosener, S.3
Just, I.4
Hall, A.5
-
16
-
-
0024449589
-
The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells
-
Chardin, P. et al. The mammalian G protein rho C is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilament in Vero cells. EMBO J. 8, 1087-1092 (1989). (Pubitemid 19273274)
-
(1989)
EMBO Journal
, vol.8
, Issue.4
, pp. 1087-1092
-
-
Chardin, P.1
Boquet, P.2
Madaule, P.3
Popoff, M.R.4
Rubin, E.J.5
Gill, D.M.6
-
17
-
-
17844406602
-
Bacterial cytotoxins: Targeting eukaryotic switches
-
DOI 10.1038/nrmicro1150
-
Aktories, K. & Barbieri, J. T. Bacterial cytotoxins: targeting eukaryotic switches. Nature Rev. Microbiol. 3, 397-410 (2005). (Pubitemid 40590382)
-
(2005)
Nature Reviews Microbiology
, vol.3
, Issue.5
, pp. 397-410
-
-
Aktories, K.1
Barbieri, J.T.2
-
18
-
-
0038062664
-
Bacterial virulence factors targeting Rho GTPases: Parasitism or symbiosis?
-
DOI 10.1016/S0962-8924(03)00037-0
-
Boquet, P. & Lemichez, E. Bacterial virulence factors targeting Rho GTPases: parasitism or symbiosis? Trends Cell Biol. 13, 238-246 (2003). (Pubitemid 36556008)
-
(2003)
Trends in Cell Biology
, vol.13
, Issue.5
, pp. 238-246
-
-
Boquet, P.1
Lemichez, E.2
-
19
-
-
0025195876
-
Microinjection of recombinant p21rho induces rapid changes in cell morphology
-
Paterson, H. F. et al. Microinjection of recombinant p21rho induces rapid changes in cell morphology. J. Cell Biol. 111, 1001-1007 (1990).
-
(1990)
J. Cell Biol.
, vol.111
, pp. 1001-1007
-
-
Paterson, H.F.1
-
20
-
-
2142713987
-
Snails Swiss and serum: The solution for Rac 'n'
-
Ridley, A. J. & Hall, A. Snails, Swiss, and serum: the solution for Rac 'n' Rho. Cell 116, S23-S25 (2004).
-
(2004)
Rho. Cell
, vol.116
-
-
Ridley, A.J.1
Hall, A.2
-
21
-
-
0032577563
-
S. typhimurium Encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells
-
DOI 10.1016/S0092-8674(00)81442-7
-
Hardt, W. D., Chen, L. M., Schuebel, K. E., Bustelo, X. R. & Galan, J. E. S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells. Cell 93, 815-826 (1998). (Pubitemid 28257587)
-
(1998)
Cell
, vol.93
, Issue.5
, pp. 815-826
-
-
Hardt, W.-D.1
Chen, L.-M.2
Schuebel, K.E.3
Bustelo, X.R.4
Galan, J.E.5
-
22
-
-
0036646473
-
Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE
-
DOI 10.1093/emboj/cdf329
-
Buchwald, G. et al. Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE. EMBO J. 21, 3286-3295 (2002). (Pubitemid 34760561)
-
(2002)
EMBO Journal
, vol.21
, Issue.13
, pp. 3286-3295
-
-
Buchwald, G.1
Friebel, A.2
Galan, J.E.3
Hardt, W.-D.4
Wittinghofer, A.5
Scheffzek, K.6
-
23
-
-
0041530031
-
A Burkholderia pseudomallei type III secreted protein, BopE, facilitates bacterial invasion of epithelial cells and exhibits guanine nucleotide exchange factor activity
-
DOI 10.1128/JB.185.16.4992-4996.2003
-
Stevens, M. P. et al. A Burkholderia pseudomallei type III secreted protein, BopE, facilitates bacterial invasion of epithelial cells and exhibits guanine nucleotide exchange factor activity. J. Bacteriol. 185, 4992-4996 (2003). (Pubitemid 36962307)
-
(2003)
Journal of Bacteriology
, vol.185
, Issue.16
, pp. 4992-4996
-
-
Stevens, M.P.1
Friebel, A.2
Taylor, L.A.3
Wood, M.W.4
Brown, P.J.5
Hardt, W.-D.6
Galyov, E.E.7
-
24
-
-
21244451603
-
IpgB1 is a novel Shigella effector protein involved in bacterial invasion of host cells: Its activity to promote membrane ruffling via Rac1 and Cdc42 activation
-
DOI 10.1074/jbc.M502509200
-
Ohya, K., Handa, Y., Ogawa, M., Suzuki, M. & Sasakawa, C. IpgB1 is a novel Shigella effector protein involved in bacterial invasion of host cells. Its activity to promote membrane ruffling via Rac1 and Cdc42 activation. J. Biol. Chem. 280, 24022-24034 (2005). (Pubitemid 40884890)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.25
, pp. 24022-24034
-
-
Ohya, K.1
Handa, Y.2
Ogawa, M.3
Suzuki, M.4
Sasakawa, C.5
-
25
-
-
30344455042
-
Identification of a bacterial type III effector family with G protein mimicry functions
-
DOI 10.1016/j.cell.2005.10.031, PII S0092867405012298
-
Alto, N. M. et al. Identification of a bacterial type III effector family with G protein mimicry functions. Cell 124, 133-145 (2006). (Pubitemid 43069315)
-
(2006)
Cell
, vol.124
, Issue.1
, pp. 133-145
-
-
Alto, N.M.1
Shao, F.2
Lazar, C.S.3
Brost, R.L.4
Chua, G.5
Mattoo, S.6
McMahon, S.A.7
Ghosh, P.8
Hughes, T.R.9
Boone, C.10
Dixon, J.E.11
-
26
-
-
77952767396
-
Structure of Shigella IpgB2 in complex with human RhoA: Implications for the mechanism of bacterial guanine nucleotide exchange factor mimicry
-
Klink, B. U. et al. Structure of Shigella IpgB2 in complex with human RhoA: implications for the mechanism of bacterial guanine nucleotide exchange factor mimicry. J. Biol. Chem. 285, 17197-17208 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 17197-17208
-
-
Klink, B.U.1
-
27
-
-
77954295385
-
EspM2 is a RhoA guanine nucleotide exchange factor
-
Arbeloa, A. et al. EspM2 is a RhoA guanine nucleotide exchange factor. Cell. Microbiol. 12, 654-664 (2010).
-
(2010)
Cell. Microbiol.
, vol.12
, pp. 654-664
-
-
Arbeloa, A.1
-
28
-
-
58349102325
-
EspT triggers formation of lamellipodia and membrane ruffles through activation of Rac-1 and Cdc42
-
Bulgin, R. R., Arbeloa, A., Chung, J. C. & Frankel, G. EspT triggers formation of lamellipodia and membrane ruffles through activation of Rac-1 and Cdc42. Cell. Microbiol. 11, 217-229 (2009).
-
(2009)
Cell. Microbiol.
, vol.11
, pp. 217-229
-
-
Bulgin, R.R.1
Arbeloa, A.2
Chung, J.C.3
Frankel, G.4
-
29
-
-
55249084667
-
Structure and function of Salmonella SifA indicate that its interactions with SKIP SseJ, and RhoA family GTPases induce endosomal tubulation
-
Ohlson, M. B. et al. Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation. Cell Host Microbe 4, 434-446 (2008).
-
(2008)
Cell Host Microbe
, vol.4
, pp. 434-446
-
-
Ohlson, M.B.1
-
30
-
-
55249103138
-
Mimicry is the sincerest form of flattery?
-
Hume, P. J. & Koronakis, V. Mimicry is the sincerest form of flattery? Cell Host Microbe 4, 411-412 (2008).
-
(2008)
Cell Host Microbe
, vol.4
, pp. 411-412
-
-
Hume, P.J.1
Koronakis, V.2
-
31
-
-
84889234826
-
Targeting of Host Rab GTPase Function by the Intravacuolar Pathogen Legionella pneumophila
-
DOI 10.1016/j.devcel.2006.05.013, PII S1534580706002541
-
Machner, M. P. & Isberg, R. R. Targeting of host Rab GTPase function by the intravacuolar pathogen Legionella pneumophila. Dev. Cell 11, 47-56 (2006). (Pubitemid 43960806)
-
(2006)
Developmental Cell
, vol.11
, Issue.1
, pp. 47-56
-
-
Machner, M.P.1
Isberg, R.R.2
-
32
-
-
33748172869
-
The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor
-
DOI 10.1038/ncb1463, PII NCB1463
-
Murata, T. et al. The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor. Nature Cell Biol. 8, 971-977 (2006). (Pubitemid 44314728)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.9
, pp. 971-977
-
-
Murata, T.1
Delprato, A.2
Ingmundson, A.3
Toomre, D.K.4
Lambright, D.G.5
Roy, C.R.6
-
33
-
-
77949498580
-
Structural mechanism of host Rab1 activation by the bifunctional Legionella type IV effector SidM/DrrA
-
Zhu, Y. et al. Structural mechanism of host Rab1 activation by the bifunctional Legionella type IV effector SidM/DrrA. Proc. Natl Acad. Sci. USA 107, 4699-4704 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 4699-4704
-
-
Zhu, Y.1
-
34
-
-
72449132474
-
RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity
-
Schoebel, S., Oesterlin, L. K., Blankenfeldt, W., Goody, R. S. & Itzen, A. RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity. Mol. Cell 36, 1060-1072 (2009).
-
(2009)
Mol. Cell
, vol.36
, pp. 1060-1072
-
-
Schoebel, S.1
Oesterlin, L.K.2
Blankenfeldt, W.3
Goody, R.S.4
Itzen, A.5
-
35
-
-
78650973579
-
The assembly of a GTPase-kinase signalling complex by a bacterial catalytic scaffold
-
Selyunin, A. S. et al. The assembly of a GTPase-kinase signalling complex by a bacterial catalytic scaffold. Nature 469, 107-111 (2011).
-
(2011)
Nature
, vol.469
, pp. 107-111
-
-
Selyunin, A.S.1
-
36
-
-
0035834388
-
The guanine nucleotide-binding switch in three dimensions
-
DOI 10.1126/science.1062023
-
Vetter, I. R. & Wittinghofer, A. The guanine nucleotide-binding switch in three dimensions. Science 294, 1299-1304 (2001). (Pubitemid 33063089)
-
(2001)
Science
, vol.294
, Issue.5545
, pp. 1299-1304
-
-
Vetter, I.R.1
Wittinghofer, A.2
-
37
-
-
0033575956
-
A Salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion
-
Fu, Y. & Galan, J. E. A Salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion. Nature 401, 293-297 (1999).
-
(1999)
Nature
, vol.401
, pp. 293-297
-
-
Fu, Y.1
Galan, J.E.2
-
38
-
-
0034097414
-
GAP activity of the Yersinia YopE cytotoxin specifically targets the Rho pathway: A mechanism for disruption of actin microfilament structure
-
DOI 10.1046/j.1365-2958.2000.01898.x
-
von Pawel-Rammingen, U. et al. GAP activity of the Yersinia YopE cytotoxin specifically targets the Rho pathway: a mechanism for disruption of actin microfilament structure. Mol. Microbiol. 36, 737-748 (2000). (Pubitemid 30258856)
-
(2000)
Molecular Microbiology
, vol.36
, Issue.3
, pp. 737-748
-
-
Von Pawel-Rammingen, U.1
Telepnev, M.V.2
Schmidt, G.3
Aktories, K.4
Wolf-Watz, H.5
Rosqvist, R.6
-
39
-
-
0033579479
-
The N-terminal domain of Pseudomonas aeruginosa exoenzyme S is a GTPase-activating protein for Rho GTPases
-
Goehring, U.-M., Schmidt, G., Pederson, K. J., Aktories, K. & Barbieri, J. T. The N-terminal domain of Pseudomonas aeruginosa exoenzyme S is a GTPase-activating protein for Rho GTPases. J. Biol. Chem. 274, 36369-36372 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 36369-36372
-
-
Goehring, U.-M.1
Schmidt, G.2
Pederson, K.J.3
Aktories, K.4
Barbieri, J.T.5
-
40
-
-
0033796738
-
Pseudomonas aeruginosa ExoT is a Rho GTPase-activating protein
-
Krall, R., Schmidt, G., Aktories, K. & Barbieri, J. T. Pseudomonas aeruginosa ExoT is a Rho GTPase-activating protein. Infect. Immun. 68, 6066-6068 (2000).
-
(2000)
Infect. Immun.
, vol.68
, pp. 6066-6068
-
-
Krall, R.1
Schmidt, G.2
Aktories, K.3
Barbieri, J.T.4
-
41
-
-
53849133471
-
Molecular mechanisms of the cytotoxicity of ADP-ribosylating toxins
-
Deng, Q. & Barbieri, J. T. Molecular mechanisms of the cytotoxicity of ADP-ribosylating toxins. Annu. Rev. Microbiol. 62, 271-288 (2008).
-
(2008)
Annu. Rev. Microbiol.
, vol.62
, pp. 271-288
-
-
Deng, Q.1
Barbieri, J.T.2
-
42
-
-
35348947419
-
Aeromonas exoenzyme T of Aeromonas salmonicida is a bifunctional protein that targets the host cytoskeleton
-
DOI 10.1074/jbc.M704797200
-
Fehr, D. et al. Aeromonas exoenzyme T of Aeromonas salmonicida is a bifunctional protein that targets the host cytoskeleton. J. Biol. Chem. 282, 28843-28852 (2007). (Pubitemid 47606029)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.39
, pp. 28843-28852
-
-
Fehr, D.1
Burr, S.E.2
Gibert, M.3
D'Alayer, J.4
Frey, J.5
Popoff, M.R.6
-
43
-
-
36249027095
-
Legionella pneumophila proteins that regulate Rab1 membrane cycling
-
DOI 10.1038/nature06336, PII NATURE06336
-
Ingmundson, A., Delprato, A., Lambright, D. G. & Roy, C. R. Legionella pneumophila proteins that regulate Rab1 membrane cycling. Nature 450, 365-369 (2007). (Pubitemid 350126758)
-
(2007)
Nature
, vol.450
, Issue.7168
, pp. 365-369
-
-
Ingmundson, A.1
Delprato, A.2
Lambright, D.G.3
Roy, C.R.4
-
44
-
-
0023110218
-
Clostridium botulinum type C produces a novel ADP-ribosyltransferase distinct from botulinum C2 toxin
-
DOI 10.1016/0014-5793(87)81566-1
-
Aktories, K., Weller, U. & Chhatwal, G. S. Clostridium botulinum type C produces a novel ADP-ribosyltransferase distinct from botulinum C2 toxin. FEBS Lett. 212, 109-113 (1987). (Pubitemid 17028086)
-
(1987)
FEBS Letters
, vol.212
, Issue.1
, pp. 109-113
-
-
Aktories, K.1
Weller, U.2
Chhatwal, G.S.3
-
45
-
-
0023779031
-
Functional modification of a 21-kilodalton G protein when ADP- ribosylated by exoenzyme C3 of Clostridium botulinum
-
Rubin, E. J., Gill, D. M., Boquet, P. & Popoff, M. R. Functional modification of a 21-kilodalton G protein when ADP- ribosylated by exoenzyme C3 of Clostridium botulinum. Mol. Cell. Biol. 8, 418-426 (1988).
-
(1988)
Mol. Cell. Biol.
, vol.8
, pp. 418-426
-
-
Rubin, E.J.1
Gill, D.M.2
Boquet, P.3
Popoff, M.R.4
-
46
-
-
0024353843
-
Asparagine residue in the rho gene product is the modification site for botulinum ADP-ribosyltransferase
-
Sekine, A., Fujiwara, M. & Narumiya, S. Asparagine residue in the rho gene product is the modification site for botulinum ADP-ribosyltransferase. J. Biol. Chem. 264, 8602-8605 (1989). (Pubitemid 19151574)
-
(1989)
Journal of Biological Chemistry
, vol.264
, Issue.15
, pp. 8602-8605
-
-
Sekine, A.1
Fujiwara, M.2
Narumiya, S.3
-
47
-
-
33646905907
-
Localization of the C3-like ADP-ribosyltransferase from Staphylococcus aureus during bacterial invasion of mammalian cells
-
DOI 10.1128/IAI.02013-05
-
Molinari, G. et al. Localization of the C3-like ADP-ribosyltransferase from Staphylococcus aureus during bacterial invasion of mammalian cells. Infect. Immun. 74, 3673-3677 (2006). (Pubitemid 43794560)
-
(2006)
Infection and Immunity
, vol.74
, Issue.6
, pp. 3673-3677
-
-
Molinari, G.1
Rohde, M.2
Wilde, C.3
Just, I.4
Aktories, K.5
Chhatwal, G.S.6
-
48
-
-
77649216057
-
Selective and specific internalization of clostridial C3 ADP-ribosyltransferases into macrophages and monocytes
-
Fahrer, J. et al. Selective and specific internalization of clostridial C3 ADP-ribosyltransferases into macrophages and monocytes. Cell. Microbiol. 12, 233-247 (2010).
-
(2010)
Cell. Microbiol.
, vol.12
, pp. 233-247
-
-
Fahrer, J.1
-
49
-
-
0037470548
-
Activation of phospholipase D1 by ADP-ribosylated RhoA
-
DOI 10.1016/S0006-291X(03)00112-8
-
Genth, H., Schmidt, M., Gerhard, R., Aktories, K. & Just, I. Activation of phospholipase D1 by ADP-ribosylated RhoA. Biochem. Biophys. Res. Commun. 302, 127-132 (2003). (Pubitemid 36268929)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.302
, Issue.1
, pp. 127-132
-
-
Genth, H.1
Schmidt, M.2
Gerhard, R.3
Aktories, K.4
Just, I.5
-
50
-
-
0041707712
-
Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 exoenzyme in the Rho-guanine nucleotide dissociation inhibitor-1 complex
-
DOI 10.1074/jbc.M301915200
-
Genth, H. et al. Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 exoenzyme in the Rho-guanine nucleotide dissociation inhibitor-1 complex. J. Biol. Chem. 278, 28523-28527 (2003). (Pubitemid 36935755)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.31
, pp. 28523-28527
-
-
Genth, H.1
Gerhard, R.2
Maeda, A.3
Amano, M.4
Kaibuchi, K.5
Aktories, K.6
Just, I.7
-
51
-
-
0032515914
-
Glucosylation and ADP ribosylation of Rho proteins: Effects on nucleotide binding, GTPase activity, and effector coupling
-
DOI 10.1021/bi972592c
-
Sehr, P. et al. Glucosylation and ADP-ribosylation of Rho proteins; effects on nucleotide binding, GTPase activity, and effector-coupling. Biochemistry 37, 5296-5304 (1998). (Pubitemid 28176531)
-
(1998)
Biochemistry
, vol.37
, Issue.15
, pp. 5296-5304
-
-
Sehr, P.1
Joseph, G.2
Genth, H.3
Just, I.4
Pick, E.5
Aktories, K.6
-
52
-
-
0025778012
-
Alteration of the cytoskeleton of mammalian cells cultured in vitro by Clostridium botulinum C2 toxin and C3 ADP-ribosyltransferase
-
Wiegers, W. et al. Alteration of the cytoskeleton of mammalian cells cultured in vitro by Clostridium botulinum C2 toxin and C3 ADP- ribosyltransferase. Eur. J. Cell Biol. 54, 237-245 (1991).
-
(1991)
Eur. J. Cell Biol.
, vol.54
, pp. 237-245
-
-
Wiegers, W.1
-
53
-
-
33846814964
-
C3 exoenzymes, novel insights into structure and action of Rho-ADP-ribosylating toxins
-
DOI 10.1007/s00210-006-0113-y
-
Vogelsgesang, M., Pautsch, A. & Aktories, K. C3 exoenzymes, novel insights into structure and action of Rho-ADP-ribosylating toxins. Naunyn Schmiedebergs Arch. Pharmacol. 374, 347-360 (2007). (Pubitemid 46215285)
-
(2007)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.374
, Issue.5-6
, pp. 347-360
-
-
Vogelsgesang, M.1
Pautsch, A.2
Aktories, K.3
-
54
-
-
33747404594
-
Induction of transient macroapertures in endothelial cells through RhoA inhibition by Staphylococcus aureus factors
-
DOI 10.1083/jcb.200509009
-
Boyer, L. et al. Induction of transient macroapertures in endothelial cells through RhoA inhibition by Staphylococcus aureus factors. J. Cell Biol. 173, 809-819 (2006). (Pubitemid 46165587)
-
(2006)
Journal of Cell Biology
, vol.173
, Issue.5
, pp. 809-819
-
-
Boyer, L.1
Doye, A.2
Rolando, M.3
Flatau, G.4
Munro, P.5
Gounon, P.6
Clement, R.7
Pulcini, C.8
Popoff, M.R.9
Mettouchi, A.10
Landraud, L.11
Dussurget, O.12
Lemichez, E.13
-
55
-
-
77955302345
-
The Staphylococcus aureus epidermal cell differentiation inhibitor toxin promotes formation of infection foci in a mouse model of bacteremia
-
Munro, P. et al. The Staphylococcus aureus epidermal cell differentiation inhibitor toxin promotes formation of infection foci in a mouse model of bacteremia. Infect. Immun. 78, 3404-3411 (2010).
-
(2010)
Infect. Immun.
, vol.78
, pp. 3404-3411
-
-
Munro, P.1
-
56
-
-
27144457720
-
Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme
-
DOI 10.1038/sj.emboj.7600813, PII 7600813
-
Pautsch, A., Vogelsgesang, M., Trankle, J., Herrmann, C. & Aktories, K. Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme. EMBO J. 24, 3670-3680 (2005). (Pubitemid 41509373)
-
(2005)
EMBO Journal
, vol.24
, Issue.20
, pp. 3670-3680
-
-
Pautsch, A.1
Vogelsgesang, M.2
Trankle, J.3
Herrmann, C.4
Aktories, K.5
-
57
-
-
0030716497
-
Structure at 1.65 Å of RhoA and its GTPase-activating protein in complex with a transition-state analogue
-
DOI 10.1038/39651
-
Rittinger, K., Walker, P. A., Eccleston, J. F., Smerdon, S. J. & Gamblin, S. J. Structure at 1.65 Å of RhoA and its GTPase-activating protein in complex with a transition-state analogue. Nature 389, 758-762 (1997). (Pubitemid 27458966)
-
(1997)
Nature
, vol.389
, Issue.6652
, pp. 758-762
-
-
Rittinger, K.1
Walker, P.A.2
Eccleston, J.F.3
Smerdon, S.J.4
Gamblin, S.J.5
-
58
-
-
0032127912
-
GTPase-activating proteins: Helping hands to complement an active site
-
DOI 10.1016/S0968-0004(98)01224-9, PII S0968000498012249
-
Scheffzek, K., Ahmadian, M. R. & Wittinghofer, A. GTPase-activating proteins: helping hands to complement an active site. Trends Biochem. Sci. 23, 257-262 (1998). (Pubitemid 28343370)
-
(1998)
Trends in Biochemical Sciences
, vol.23
, Issue.7
, pp. 257-262
-
-
Scheffzek, K.1
Ahmadian, M.R.2
Wittinghofer, A.3
-
59
-
-
77649193972
-
Photorhabdus luminescens toxins ADP-ribosylate actin and RhoA to force actin clustering
-
Lang, A. E. et al. Photorhabdus luminescens toxins ADP-ribosylate actin and RhoA to force actin clustering. Science 327, 1139-1142 (2010).
-
(2010)
Science
, vol.327
, pp. 1139-1142
-
-
Lang, A.E.1
-
60
-
-
55249105923
-
Clostridium difficile - More difficult than ever
-
Kelly, C. P. & LaMont, J. T. Clostridium difficile - more difficult than ever. N. Engl. J. Med. 359, 1932-1940 (2008).
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 1932-1940
-
-
Kelly, C.P.1
Lamont, J.T.2
-
61
-
-
42149172381
-
Heterogeneity of large clostridial toxins: Importance of Clostridium difficile toxinotypes
-
DOI 10.1111/j.1574-6976.2008.00110.x
-
Rupnik, M. Heterogeneity of large clostridial toxins: importance of Clostridium difficile toxinotypes. FEMS Microbiol. Rev. 32, 541-555 (2008). (Pubitemid 351538749)
-
(2008)
FEMS Microbiology Reviews
, vol.32
, Issue.3
, pp. 541-555
-
-
Rupnik, M.1
-
62
-
-
17444366186
-
Clostridium difficile toxins: Mechanism of action and role in disease
-
DOI 10.1128/CMR.18.2.247-263.2005
-
Voth, D. E. & Ballard, J. D. Clostridium difficile toxins: mechanism of action and role in disease. Clin. Microbiol. Rev. 18, 247-263 (2005). (Pubitemid 40548293)
-
(2005)
Clinical Microbiology Reviews
, vol.18
, Issue.2
, pp. 247-263
-
-
Voth, D.E.1
Ballard, J.D.2
-
63
-
-
0029054398
-
Glucosylation of Rho proteins by Clostridium difficile toxin B
-
Just, I. et al. Glucosylation of Rho proteins by Clostridium difficile toxin B. Nature 375, 500-503 (1995).
-
(1995)
Nature
, vol.375
, pp. 500-503
-
-
Just, I.1
-
64
-
-
15844415779
-
Ras, Rap, and Rac small GTP-binding proteins are targets for Clostridium sordellii lethal toxin glucosylation
-
DOI 10.1074/jbc.271.17.10217
-
Popoff, M. R. et al. Ras, Rap, and Rac small GTP-binding proteins are targets for Clostridium sordellii lethal toxin glucosylation. J. Biol. Chem. 271, 10217-10224 (1996). (Pubitemid 26131588)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.17
, pp. 10217-10224
-
-
Popoff, M.R.1
Chaves-Olarte, E.2
Lemichez, E.3
Von Eichel-Streiber, C.4
Thelestam, M.5
Chardin, P.6
Cussac, D.7
Antonny, B.8
Chavrier, P.9
Flatau, G.10
Giry, M.11
De Gunzburg, J.12
Boquet, P.13
-
65
-
-
0029925007
-
Inactivation of Ras by Clostridium sordellii lethal toxin-catalyzed glucosylation
-
DOI 10.1074/jbc.271.17.10149
-
Just, I., Selzer, J., Hofmann, F., Green, G. A. & Aktories, K. Inactivation of Ras by Clostridium sordellii lethal toxin-catalyzed glucosylation. J. Biol. Chem. 271, 10149-10153 (1996). (Pubitemid 26131577)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.17
, pp. 10149-10153
-
-
Just, I.1
Selzer, J.2
Hofmann, F.3
Green, G.A.4
Aktories, K.5
-
66
-
-
0029823945
-
Clostridium novyi α-toxin-catalyzed incorporation of GlcNAc into Rho subfamily proteins
-
DOI 10.1074/jbc.271.41.25173
-
Selzer, J. et al. Clostridium novyi α-toxin-catalyzed incorporation of GlcNAc into Rho subfamily proteins. J. Biol. Chem. 271, 25173-25177 (1996). (Pubitemid 26337878)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.41
, pp. 25173-25177
-
-
Selzer, J.1
Hofmann, F.2
Rex, G.3
Wilm, M.4
Mann, M.5
Just, I.6
Aktories, K.7
-
67
-
-
79251471404
-
Clostridium perfringens TpeL glycosylates the Rac and Ras subfamily proteins
-
Nagahama, M. et al. Clostridium perfringens TpeL glycosylates the Rac and Ras subfamily proteins. Infect. Immun. 79, 905-910 (2011).
-
(2011)
Infect. Immun.
, vol.79
, pp. 905-910
-
-
Nagahama, M.1
-
68
-
-
0034283341
-
Structural consequences of mono-glucosylation of Ha-Ras by Clostridium sordellii lethal toxin
-
Vetter, I. R., Hofmann, F., Wohlgemuth, S., Herrmann, C. & Just, I. Structural consequences of mono-glucosylation of Ha-Ras by Clostridium sordellii lethal toxin. J. Mol. Biol. 301, 1091-1095 (2000).
-
(2000)
J. Mol. Biol.
, vol.301
, pp. 1091-1095
-
-
Vetter, I.R.1
Hofmann, F.2
Wohlgemuth, S.3
Herrmann, C.4
Just, I.5
-
69
-
-
0142135588
-
Glucosylation of Ras by Clostridium sordellii Lethal Toxin: Consequences for Effector Loop Conformations Observed by NMR Spectroscopy
-
DOI 10.1021/bi034529v
-
Geyer, M., Wilde, C., Selzer, J., Aktories, K. & Kalbitzer, H. R. Glucosylation of Ras by Clostridium sordellii lethal toxin: consequences for the effector loop conformations observed by NMR spectroscopy. Biochemistry 42, 11951-11959 (2003). (Pubitemid 37280645)
-
(2003)
Biochemistry
, vol.42
, Issue.41
, pp. 11951-11959
-
-
Geyer, M.1
Wilde, C.2
Selzer, J.3
Aktories, K.4
Kalbitzer, H.R.5
-
70
-
-
0032831781
-
Monoglucosylation of RhoA at Threonine-37 blocks cytosol-membrane cycling
-
Genth, H., Aktories, K. & Just, I. Monoglucosylation of RhoA at Threonine-37 blocks cytosol-membrane cycling. J. Biol. Chem. 274, 29050-29056 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 29050-29056
-
-
Genth, H.1
Aktories, K.2
Just, I.3
-
71
-
-
33750944019
-
Legionella pneumophila glucosyltransferase inhibits host elongation factor 1A
-
DOI 10.1073/pnas.0601562103
-
Belyi, Y. et al. Legionella pneumophila glucosyltransferase inhibits host elongation factor 1A. Proc. Natl Acad. Sci. USA 103, 16953-16958 (2006). (Pubitemid 44737359)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.45
, pp. 16953-16958
-
-
Belyi, Y.1
Niggeweg, R.2
Opitz, B.3
Vogelsgesang, M.4
Hippenstiel, S.5
Wilm, M.6
Aktories, K.7
-
72
-
-
58149400542
-
AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling
-
Yarbrough, M. L. et al. AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling. Science 323, 269-272 (2009).
-
(2009)
Science
, vol.323
, pp. 269-272
-
-
Yarbrough, M.L.1
-
73
-
-
67149136177
-
Fido a novel AMPylation domain common to fic, doc, and AvrB
-
Kinch, L. N., Yarbrough, M. L., Orth, K. & Grishin, N. V. Fido, a novel AMPylation domain common to fic, doc, and AvrB. PLoS ONE 4, e5818 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Kinch, L.N.1
Yarbrough, M.L.2
Orth, K.3
Grishin, N.V.4
-
74
-
-
42949152423
-
Vibrio parahaemolyticus inhibition of Rho family GTPase activation requires a functional chromosome I type III secretion system
-
DOI 10.1128/IAI.01704-07
-
Casselli, T., Lynch, T., Southward, C. M., Jones, B. W. & DeVinney, R. Vibrio parahaemolyticus inhibition of Rho family GTPase activation requires a functional chromosome I type III secretion system. Infect. Immun. 76, 2202-2211 (2008). (Pubitemid 351656156)
-
(2008)
Infection and Immunity
, vol.76
, Issue.5
, pp. 2202-2211
-
-
Casselli, T.1
Lynch, T.2
Southward, C.M.3
Jones, B.W.4
DeVinney, R.5
-
75
-
-
63649139064
-
The Fic domain: Regulation of cell signaling by adenylylation
-
Worby, C. A. et al. The Fic domain: regulation of cell signaling by adenylylation. Mol. Cell 34, 93-103 (2009).
-
(2009)
Mol. Cell
, vol.34
, pp. 93-103
-
-
Worby, C.A.1
-
76
-
-
77955416465
-
Structural basis of Fic-mediated adenylylation
-
Xiao, J., Worby, C. A., Mattoo, S., Sankaran, B. & Dixon, J. E. Structural basis of Fic-mediated adenylylation. Nature Struct. Mol. Biol. 17, 1004-1010 (2010).
-
(2010)
Nature Struct. Mol. Biol.
, vol.17
, pp. 1004-1010
-
-
Xiao, J.1
Worby, C.A.2
Mattoo, S.3
Sankaran, B.4
Dixon, J.E.5
-
77
-
-
2442646538
-
Molecular and cell biology of Legionella pneumophila
-
DOI 10.1078/1438-4221-00286
-
Bitar, D. M., Molmeret, M. & Abu, K. Y. Molecular and cell biology of Legionella pneumophila. Int. J. Med. Microbiol. 293, 519-527 (2004). (Pubitemid 38667575)
-
(2004)
International Journal of Medical Microbiology
, vol.293
, Issue.7-8
, pp. 519-527
-
-
Bitar, D.M.1
Molmeret, M.2
Abu Kwaik, Y.3
-
78
-
-
3142512687
-
Differentiate to thrive: Lessons from the Legionella pneumophila life cycle
-
DOI 10.1111/j.1365-2958.2004.04129.x
-
Molofsky, A. B. & Swanson, M. S. Differentiate to thrive: lessons from the Legionella pneumophila life cycle. Mol. Microbiol. 53, 29-40 (2004). (Pubitemid 38901377)
-
(2004)
Molecular Microbiology
, vol.53
, Issue.1
, pp. 29-40
-
-
Molofsky, A.B.1
Swanson, M.S.2
-
79
-
-
84889234796
-
A bifunctional bacterial protein links GDI displacement to Rab1 activation
-
DOI 10.1126/science.1149121
-
Machner, M. P. & Isberg, R. R. A bifunctional bacterial protein links GDI displacement to Rab1 activation. Science 318, 974-977 (2007). (Pubitemid 350098993)
-
(2007)
Science
, vol.318
, Issue.5852
, pp. 974-977
-
-
Machner, M.P.1
Isberg, R.R.2
-
80
-
-
64149084796
-
Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila
-
Brombacher, E. et al. Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila. J. Biol. Chem. 284, 4846-4856 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 4846-4856
-
-
Brombacher, E.1
-
81
-
-
77955872117
-
The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b
-
Muller, M. P. et al. The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b. Science 329, 946-949 (2010).
-
(2010)
Science
, vol.329
, pp. 946-949
-
-
Muller, M.P.1
-
82
-
-
66149098151
-
Bacterial FIC proteins AMP up infection
-
Roy, C. R. & Mukherjee, S. Bacterial FIC proteins AMP up infection. Sci. Signal. 2, e14 (2009).
-
(2009)
Sci. Signal.
, vol.2
-
-
Roy, C.R.1
Mukherjee, S.2
-
83
-
-
0037205231
-
A Yersinia effector and a Pseudomonas avirulence protein define a family of cysteine proteases functioning in bacterial pathogenesis
-
DOI 10.1016/S0092-8674(02)00766-3
-
Shao, F., Merritt, P. M., Bao, Z., Innes, R. W. & Dixon, J. E. A Yersinia effector and a Pseudomonas avirulence protein define a family of cycteine proteases functioning in bacterial pathogenesis. Cell 109, 575-588 (2002). (Pubitemid 34628721)
-
(2002)
Cell
, vol.109
, Issue.5
, pp. 575-588
-
-
Shao, F.1
Merritt, P.M.2
Bao, Z.3
Innes, R.W.4
Dixon, J.E.5
-
84
-
-
0037417878
-
Biochemical characterization of the Yersinia YopT protease: Cleavage site and recognition elements in Rho GTPases
-
DOI 10.1073/pnas.252770599
-
Shao, F. et al. Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases. Proc. Natl Acad. Sci. USA 100, 904-909 (2003). (Pubitemid 36183928)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.3
, pp. 904-909
-
-
Shao, F.1
Vacratsis, P.O.2
Bao, Z.3
Bowerst, K.E.4
Fierke, C.A.5
Dixon, J.E.6
-
85
-
-
0035184874
-
Recombinant Yersinia YopT leads to uncoupling of RhoA-effector Interaction
-
DOI 10.1128/IAI.69.12.7535-7543.2001
-
Sorg, I., Goehring, U.-M., Aktories, K. & Schmidt, G. Recombinant Yersinia YopT leads to uncoupling of RhoA-effector interaction. Infect. Immun. 69, 7535-7543 (2001). (Pubitemid 33089239)
-
(2001)
Infection and Immunity
, vol.69
, Issue.12
, pp. 7535-7543
-
-
Sorg, I.1
Goehring, U.-M.2
Aktories, K.3
Schmidt, G.4
-
86
-
-
0042357172
-
Characterization of YopT effects on Rho GTPases in Yersinia enterocolitica-infected cells
-
DOI 10.1074/jbc.M303349200
-
Aepfelbacher, M. et al. Characterization of YopT effects on Rho GTPases in Yersinia enterocolitica-infected cells. J. Biol. Chem. 278, 33217-33223 (2003). (Pubitemid 37055770)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.35
, pp. 33217-33223
-
-
Aepfelbacher, M.1
Trasak, C.2
Wilharm, G.3
Wiedemann, A.4
Trulzsch, K.5
Krauss, K.6
Gierschik, P.7
Heesemann, J.8
-
87
-
-
70350453627
-
Yersinia pseudotuberculosis virulence determinants invasin YopE, and YopT modulate RhoG activity and localization
-
Mohammadi, S. & Isberg, R. R. Yersinia pseudotuberculosis virulence determinants invasin, YopE, and YopT modulate RhoG activity and localization. Infect. Immun. 77, 4771-4782 (2009).
-
(2009)
Infect. Immun.
, vol.77
, pp. 4771-4782
-
-
Mohammadi, S.1
Isberg, R.R.2
-
88
-
-
43149116339
-
Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division
-
DOI 10.1083/jcb.200801047
-
Michaelson, D. et al. Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division. J. Cell Biol. 181, 485-496 (2008). (Pubitemid 351645038)
-
(2008)
Journal of Cell Biology
, vol.181
, Issue.3
, pp. 485-496
-
-
Michaelson, D.1
Abidi, W.2
Guardavaccaro, D.3
Zhou, M.4
Ahearn, I.5
Pagano, M.6
Philips, M.R.7
-
89
-
-
0038485593
-
Novel mechanism of the co-regulation of nuclear transport of SmgGDS and Rac1
-
DOI 10.1074/jbc.M211286200
-
Lanning, C. C., Ruiz-Velasco, R. & Williams, C. L. Novel mechanism of the co-regulation of nuclear transport of SmgGDS and Rac1. J. Biol. Chem. 278, 12495-12506 (2003). (Pubitemid 36800238)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.14
, pp. 12495-12506
-
-
Lanning, C.C.1
Ruiz-Velasco, R.2
Williams, C.L.3
-
90
-
-
6344231828
-
The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1
-
DOI 10.1074/jbc.M404977200
-
Lanning, C. C., Daddona, J. L., Ruiz-Velasco, R., Shafer, S. H. & Williams, C. L. The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1. J. Biol. Chem. 279, 44197-44210 (2004). (Pubitemid 39390727)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.42
, pp. 44197-44210
-
-
Lanning, C.C.1
Daddona, J.L.2
Ruiz-Velasco, R.3
Shafer, S.H.4
Williams, C.L.5
-
91
-
-
0034695446
-
CD44 interaction with Tiam1 promotes Rac1 signaling and hyaluronic acid- mediated breast tumor cell migration
-
DOI 10.1074/jbc.275.3.1829
-
Bourguignon, L. Y. W., Zhu, H., Shao, L. & Chen, Y. W. CD44 interaction with Tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration. J. Biol. Chem. 275, 1829-1838 (2000). (Pubitemid 30060806)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.3
, pp. 1829-1838
-
-
Bourguignon, L.Y.W.1
Hongbo, Z.2
Shao, L.3
Chen, Y.W.4
-
92
-
-
14044279227
-
Site-specific antiphagocytic function of the Photorhabdus luminescens type III secretion system during insect colonization
-
DOI 10.1111/j.1462-5822.2004.00466.x
-
Brugirard-Ricaud, K. et al. Site-specific antiphagocytic function of the Photorhabdus luminescens type III secretion system during insect colonization. Cell. Microbiol. 7, 363-371 (2005). (Pubitemid 40277916)
-
(2005)
Cellular Microbiology
, vol.7
, Issue.3
, pp. 363-371
-
-
Brugirard-Ricaud, K.1
Duchaud, E.2
Givaudan, A.3
Girard, P.A.4
Kunst, F.5
Boemare, N.6
Brehelin, M.7
Zumbihl, R.8
-
93
-
-
67650115862
-
A family of bacterial cysteine protease type III effectors utilizes acylation-dependent and -independent strategies to localize to plasma membranes
-
Dowen, R. H., Engel, J. L., Shao, F., Ecker, J. R. & Dixon, J. E. A family of bacterial cysteine protease type III effectors utilizes acylation-dependent and -independent strategies to localize to plasma membranes. J. Biol. Chem. 284, 15867-15879 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 15867-15879
-
-
Dowen, R.H.1
Engel, J.L.2
Shao, F.3
Ecker, J.R.4
Dixon, J.E.5
-
94
-
-
0028231764
-
Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers
-
Oswald, E. et al. Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers. Proc. Natl Acad. Sci. USA 91, 3814-3818 (1994). (Pubitemid 24139522)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.9
, pp. 3814-3818
-
-
Oswald, E.1
Sugai, M.2
Labigne, A.3
Wu, H.C.4
Fiorentini, C.5
Boquet, P.6
O'Brien, A.D.7
-
95
-
-
0025707559
-
A single protein of 110 kDa is associated with the multinucleating and necrotizing activity coded by the Vir plasmid of Escherichia coli
-
Oswald, E. & de Rycke, J. A single protein of 110 kDa is associated with the multinucleating and necrotizing activity coded by the Vir plasmid of Escherichia coli. FEMS Microbiol. Lett. 68, 279-284 (1990). (Pubitemid 20088764)
-
(1990)
FEMS Microbiology Letters
, vol.68
, Issue.3
, pp. 279-284
-
-
Oswald, E.1
De Rycke, J.2
-
96
-
-
68949145965
-
A new member of a growing toxin family - Escherichia coli cytotoxic necrotizing factor 3 (CNF3)
-
Stoll, T., Markwirth, G., Reipschlager, S. & Schmidt, G. A new member of a growing toxin family - Escherichia coli cytotoxic necrotizing factor 3 (CNF3). Toxicon 54, 745-753 (2009).
-
(2009)
Toxicon
, vol.54
, pp. 745-753
-
-
Stoll, T.1
Markwirth, G.2
Reipschlager, S.3
Schmidt, G.4
-
97
-
-
0036120223
-
Yersinia pseudotuberculosis produces a cytotoxic necrotizing factor
-
DOI 10.1128/IAI.70.5.2708-2714.2002
-
Lockman, H. A., Gillespie, R. A., Baker, B. D. & Shakhnovich, E. Yersinia pseudotuberculosis produces a cytotoxic necrotizing factor. Infect. Immun. 70, 2708-2714 (2002). (Pubitemid 34408421)
-
(2002)
Infection and Immunity
, vol.70
, Issue.5
, pp. 2708-2714
-
-
Lockman, H.A.1
Gillespie, R.A.2
Baker, B.D.3
Shakhnovich, E.4
-
98
-
-
0030742773
-
Molecular localization of the Escherichia coli cytotoxic necrotizing factor CNF1 cell-binding and catalytic domains
-
Lemichez, E., Flatau, G., Bruzzone, M., Boquet, P. & Gauthier, M. Molecular localization of the Escherichia coli cytotoxic necrotizing factor CNF1 cell-binding and catalytic domains. Mol. Microbiol. 24, 1061-1070 (1997). (Pubitemid 27286157)
-
(1997)
Molecular Microbiology
, vol.24
, Issue.5
, pp. 1061-1070
-
-
Lemichez, E.1
Flatau, G.2
Bruzzone, M.3
Boquet, P.4
Gauthier, M.5
-
99
-
-
12544255191
-
67-kDa laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Escherichia coli K1 into human brain microvascular endothelial cells
-
Kim, K. J., Chung, J. W. & Kim, K. S. 67-kDa laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Escherichia coli K1 into human brain microvascular endothelial cells. J. Biol. Chem. 280, 1360-1368 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1360-1368
-
-
Kim, K.J.1
Chung, J.W.2
Kim, K.S.3
-
100
-
-
34447253589
-
The cytotoxic necrotizing factors from Yersinia pseudotuberculosis and from Escherichia coli bind to different cellular receptors but take the same route to the cytosol
-
DOI 10.1128/IAI.01937-06
-
Blumenthal, B., Hoffmann, C., Aktories, K., Backert, S. & Schmidt, G. The cytotoxic necrotizing factors from Yersinia pseudotuberculosis and from Escherichia coli bind to different cellular receptors but take the same route to the cytosol. Infect. Immun. 75, 3344-3353 (2007). (Pubitemid 47040935)
-
(2007)
Infection and Immunity
, vol.75
, Issue.7
, pp. 3344-3353
-
-
Blumenthal, B.1
Hoffmann, C.2
Aktories, K.3
Backert, S.4
Schmidt, G.5
-
101
-
-
65449144434
-
Cleavage of Escherichia coli cytotoxic necrotizing factor 1 is required for full biologic activity
-
Knust, Z., Blumenthal, B., Aktories, K. & Schmidt, G. Cleavage of Escherichia coli cytotoxic necrotizing factor 1 is required for full biologic activity. Infect. Immun. 77, 1835-1841 (2009).
-
(2009)
Infect. Immun.
, vol.77
, pp. 1835-1841
-
-
Knust, Z.1
Blumenthal, B.2
Aktories, K.3
Schmidt, G.4
-
102
-
-
0030610785
-
Gin 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1
-
DOI 10.1038/42735
-
Schmidt, G. et al. Gln63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor 1. Nature 387, 725-729 (1997). (Pubitemid 27270615)
-
(1997)
Nature
, vol.387
, Issue.6634
, pp. 725-729
-
-
Schmidt, G.1
Sehr, P.2
Wilm, M.3
Selzer, J.4
Mann, M.5
Aktories, K.6
-
103
-
-
0030992838
-
Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine
-
DOI 10.1038/42743
-
Flatau, G. et al. Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine. Nature 387, 729-733 (1997). (Pubitemid 27270616)
-
(1997)
Nature
, vol.387
, Issue.6634
, pp. 729-733
-
-
Flatau, G.1
Lemichez, E.2
Gauthier, M.3
Chardin, P.4
Paris, S.5
Florentini, C.6
Boquet, P.7
-
104
-
-
0034953089
-
Structure of the Rho-activating domain of Escherichia coli cytotoxic necrotizing factor 1
-
DOI 10.1038/89610
-
Buetow, L., Flatau, G., Chiu, K., Boquet, P. & Ghosh, P. Structure of the Rho-activating domain of Escherichia coli cytotoxic necrotizing factor 1. Nature Struct. Biol. 8, 584-588 (2001). (Pubitemid 32613004)
-
(2001)
Nature Structural Biology
, vol.8
, Issue.7
, pp. 584-588
-
-
Buetow, L.1
Flatau, G.2
Chiu, K.3
Boquet, P.4
Ghosh, P.5
-
105
-
-
0032867338
-
Identification of the region of Rho involved in substrate recognition by Escherichia coli cytotoxic necrotizing factor 1 (CNF1)
-
Lerm, M., Schmidt, G., Goehring, U.-M., Schirmer, J. & Aktories, K. Identification of the region of Rho involved in substrate recognition by Escherichia coli cytotoxic necrotizing factor 1 (CNF1). J. Biol. Chem. 274, 28999-29004 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28999-29004
-
-
Lerm, M.1
Schmidt, G.2
Goehring, U.-M.3
Schirmer, J.4
Aktories, K.5
-
106
-
-
17444434479
-
Interaction of Escherichia coli cytotoxic necrotizing factor type 1 (CNF1) with cultured cells
-
Falzano, L., Fiorentini, C., Boquet, P. & Donelli, G. Interaction of Escherichia coli cytotoxic necrotizing factor type 1 (CNF1) with cultured cells. Cytotechnology 11, S56-S58 (1993).
-
(1993)
Cytotechnology
, vol.11
-
-
Falzano, L.1
Fiorentini, C.2
Boquet, P.3
Donelli, G.4
-
107
-
-
0024638664
-
Cytotoxic effect of multinucleation in HeLa cell cultures associated with the presence of Vir plasmid in Escherichia coli strains
-
Oswald, E., de Rycke, J., Guillot, J. F. & Boivin, R. Cytotoxic effect of multinucleation in HeLa cell cultures associated with the presence of Vir plasmid in Escherichia coli strains. FEMS Microbiol. Lett. 58, 95-100 (1989).
-
(1989)
FEMS Microbiol. Lett.
, vol.58
, pp. 95-100
-
-
Oswald, E.1
De Rycke, J.2
Guillot, J.F.3
Boivin, R.4
-
108
-
-
0031563151
-
Uncoupling of S-phase and mitosis by recombinant cytotoxic necrotizing factor 2 (CNF2)
-
DOI 10.1006/excr.1997.3595
-
Denko, N., Langland, R., Barton, M. & Lieberman, M. A. Uncoupling of S-phase and mitosis by recombinant cytotoxic necrotizing factor 2 (CNF2). Exp. Cell Res. 234, 132-138 (1997). (Pubitemid 27317910)
-
(1997)
Experimental Cell Research
, vol.234
, Issue.1
, pp. 132-138
-
-
Denko, N.1
Langland, R.2
Barton, M.3
Lieberman, M.A.4
-
109
-
-
33646268174
-
Is the Rac GTPase-activating toxin CNF1 a smart hijacker of host cell fate?
-
DOI 10.1096/fj.05-4706hyp
-
Malorni, W. & Fiorentini, C. Is the Rac GTPase-activating toxin CNF1 a smart hijacker of host cell fate? FASEB J. 20, 606-609 (2006). (Pubitemid 44933304)
-
(2006)
FASEB Journal
, vol.20
, Issue.6
, pp. 606-609
-
-
Malorni, W.1
Fiorentini, C.2
-
110
-
-
1942469488
-
y) Selectively Activates RhoA
-
DOI 10.1074/jbc.M313556200
-
Hoffmann, C. et al. The Yersinia pseudotuberculosis cytotoxic necrotizing factor (CNFY) selectively activates RhoA. J. Biol. Chem. 279, 16026-16032 (2004). (Pubitemid 38509292)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.16
, pp. 16026-16032
-
-
Hoffmann, C.1
Pop, M.2
Leemhuis, J.3
Schirmer, J.4
Aktories, K.5
Schmidt, G.6
-
111
-
-
0036070562
-
Proteasomal degradation of cytotoxic necrotizing factor 1-activated Rac
-
DOI 10.1128/IAI.70.8.4053-4058.2002
-
Lerm, M., Pop, M., Fritz, G., Aktories, K. & Schmidt, G. Proteasomal degradation of cytotoxic necrotizing factor 1-activated Rac. Infect. Immun. 70, 4053-4058 (2002). (Pubitemid 34790912)
-
(2002)
Infection and Immunity
, vol.70
, Issue.8
, pp. 4053-4058
-
-
Lerm, M.1
Pop, M.2
Fritz, G.3
Aktories, K.4
Schmidt, G.5
-
112
-
-
33744755685
-
-/- cells
-
DOI 10.1091/mbc.E05-09-0876
-
Boyer, L. et al. CNF1-induced ubiquitylation and proteasome destruction of activated RhoA is impaired in Smurf1cells. Mol. Biol. Cell 17, 2489-2497 (2006). (Pubitemid 43825488)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.6
, pp. 2489-2497
-
-
Boyer, L.1
Turchi, L.2
Desnues, B.3
Doye, A.4
Ponzio, G.5
Mege, J.-L.6
Yamashita, M.7
Zhang, Y.E.8
Bertoglio, J.9
Flatau, G.10
Boquet, P.11
Lemichez, E.12
-
113
-
-
18744379729
-
CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion
-
DOI 10.1016/S0092-8674(02)01132-7
-
Doye, A. et al. CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion. Cell 111, 553-564 (2002). (Pubitemid 35356560)
-
(2002)
Cell
, vol.111
, Issue.4
, pp. 553-564
-
-
Doye, A.1
Mettouchi, A.2
Bossis, G.3
Clement, R.4
Buisson-Touati, C.5
Flatau, G.6
Gagnoux, L.7
Piechaczyk, M.8
Boquet, P.9
Lemichez, E.10
-
114
-
-
4143129048
-
Activation and proteasomal degradation of Rho GTPases by cytotoxic necrotizing factor-1 elicit a controlled inflammatory response
-
DOI 10.1074/jbc.M401580200
-
Munro, P. et al. Activation and proteasomal degradation of Rho GTPases by CNF1 elicit a controlled inflammatory response. J. Biol. Chem. 279, 35849-35857 (2004). (Pubitemid 39100592)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.34
, pp. 35849-35857
-
-
Munro, P.1
Flatau, G.2
Doye, A.3
Boyer, L.4
Oregioni, O.5
Mege, J.-L.6
Landraud, L.7
Lemichez, E.8
-
115
-
-
0024335143
-
Purification and characterization of Bordetella bronchiseptica dermonecrotic toxin
-
DOI 10.1016/0882-4010(89)90078-8
-
Horiguchi, Y., Nakai, T. & Kume, K. Purification and characterization of Bordetella bronchiseptica dermonecrotic toxin. Microb. Pathogen. 6, 361-368 (1989). (Pubitemid 19182108)
-
(1989)
Microbial Pathogenesis
, vol.6
, Issue.5
, pp. 361-368
-
-
Horiguchi, Y.1
Nakai, T.2
Kume, K.3
-
116
-
-
79951990525
-
Bordetella dermonecrotic toxin binds to target cells via the N-terminal 30 amino acids
-
Fukui-Miyazaki, A., Ohnishi, S., Kamitani, S., Abe, H. & Horiguchi, Y. Bordetella dermonecrotic toxin binds to target cells via the N-terminal 30 amino acids. Microbiol. Immunol. 55, 154-159 (2011).
-
(2011)
Microbiol. Immunol.
, vol.55
, pp. 154-159
-
-
Fukui-Miyazaki, A.1
Ohnishi, S.2
Kamitani, S.3
Abe, H.4
Horiguchi, Y.5
-
117
-
-
1642453672
-
Bordetella Dermonecrotic Toxin Undergoes Proteolytic Processing to Be Translocated from a Dynamin-related Endosome into the Cytoplasm in an Acidification-independent Manner
-
DOI 10.1074/jbc.M310340200
-
Matsuzawa, T. et al. Bordetella dermonecrotic toxin undergoes proteolytic processing to be translocated from a dynamin-related endosome into the cytoplasma in an acidification-independent manner. J. Biol. Chem. 279, 2866-2872 (2004). (Pubitemid 38114278)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.4
, pp. 2866-2872
-
-
Matsuzawa, T.1
Fukui, A.2
Kashimoto, T.3
Nagao, K.4
Oka, K.5
Miyake, M.6
Horiguchi, Y.7
-
118
-
-
0033527746
-
Identification of the C-terminal part of Bordetella dermonecrotic toxin as a transglutaminase for Rho GTPases
-
Schmidt, G., Goehring, U.-M., Schirmer, J., Lerm, M. & Aktories, K. Identification of the C-terminal part of Bordetella dermonecrotic toxin as a transglutaminase for Rho GTPases. J. Biol. Chem. 274, 31875-31881 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31875-31881
-
-
Schmidt, G.1
Goehring, U.-M.2
Schirmer, J.3
Lerm, M.4
Aktories, K.5
-
119
-
-
0034651790
-
Activation of Rho through a cross-link with polyamines catalyzed by Bordetella dermonecrotizing toxin
-
Masuda, M. et al. Activation of Rho through a cross-link with polyamines catalyzed by Bordetella dermonecrotizing toxin. EMBO J. 19, 521-530 (2000). (Pubitemid 30093725)
-
(2000)
EMBO Journal
, vol.19
, Issue.4
, pp. 521-530
-
-
Masuda, M.1
Betancourt, L.2
Matsuzawa, T.3
Kashimoto, T.4
Takao, T.5
Shimonishi, Y.6
Horiguchi, Y.7
-
120
-
-
0032577588
-
The Rho-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity: Cysteine 866 and histidine 881 are essential for enzyme activity
-
DOI 10.1074/jbc.273.22.13669
-
Schmidt, G., Selzer, J., Lerm, M. & Aktories, K. The Rho-deamidating cytotoxic-necrotizing factor CNF1 from Escherichia coli possesses transglutaminase activity. Cysteine-866 and histidine-881 are essential for enzyme activity. J. Biol. Chem. 273, 13669-13674 (1998). (Pubitemid 28268413)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.22
, pp. 13669-13674
-
-
Schmidt, G.1
Selzer, J.2
Lerm, M.3
Aktories, K.4
-
122
-
-
2442699051
-
The Pasteurella multocida toxin interacts, with signalling pathways to perturb cell growth and differentiation
-
DOI 10.1078/1438-4221-00287
-
Lax, A. J. et al. The Pasteurella multocida toxin interacts with signalling pathways to perturb cell growth and differentiation. Int. J. Med. Microbiol. 293, 505-512 (2004). (Pubitemid 38667573)
-
(2004)
International Journal of Medical Microbiology
, vol.293
, Issue.7-8
, pp. 505-512
-
-
Lax, A.J.1
Pullinger, G.D.2
Baldwin, M.R.3
Harmey, D.4
Grigoriadis, A.E.5
Lakey, J.H.6
-
123
-
-
66349099617
-
Pasteurella multocida toxin activation of heterotrimeric G proteins by deamidation
-
Orth, J. H. et al. Pasteurella multocida toxin activation of heterotrimeric G proteins by deamidation. Proc. Natl Acad. Sci. USA 106, 7179-7184 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 7179-7184
-
-
Orth, J.H.1
-
124
-
-
33646948992
-
New insights into the role of conserved, essential residues in the GTP binding/GTP hydrolytic cycle of large G proteins
-
DOI 10.1074/jbc.M513837200
-
Majumdar, S., Ramachandran, S. & Cerione, R. A. New insights into the role of conserved, essential residues in the GTP binding/GTP hydrolytic cycle of large G proteins. J. Biol. Chem. 281, 9219-9226 (2006). (Pubitemid 43864637)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.14
, pp. 9219-9226
-
-
Majumdar, S.1
Ramachandran, S.2
Cerione, R.A.3
-
125
-
-
0027965652
-
Structures of active conformations of Giα1 and the mechanism of GTP hydrolysis
-
Coleman, D. E. et al. Structures of active conformations of Giα1 and the mechanism of GTP hydrolysis. Science 265, 1405-1412 (1994).
-
(1994)
Science
, vol.265
, pp. 1405-1412
-
-
Coleman, D.E.1
-
126
-
-
0021321632
-
Amino acid sequence of retinal transducin at the site ADP-ribosylated by cholera toxin
-
Van Dop, C., Tsubokawa, M., Bourne, H. R. & Ramachandran, J. Amino acid sequence of retinal transducin at the site ADP-ribosylated by cholera toxin. J. Biol. Chem. 259, 696-698 (1984). (Pubitemid 14192128)
-
(1984)
Journal of Biological Chemistry
, vol.259
, Issue.2
, pp. 696-698
-
-
Van Dop, C.1
Tsubokawa, M.2
Bourne, H.R.3
Ramachandran, J.4
-
127
-
-
0024854388
-
187 results in loss of GTPase activity
-
Freissmuth, M. & Gilman, A. G. Mutations of GSα designed to alter the reactivity of the protein with bacterial toxins. Substitutions at ARG187 result in loss of GTPase activity. J. Biol. Chem. 264, 21907-21914 (1989). (Pubitemid 20028767)
-
(1989)
Journal of Biological Chemistry
, vol.264
, Issue.36
, pp. 21907-21914
-
-
Freissmuth, M.1
Gilman, A.G.2
-
128
-
-
0030920782
-
G protein mechanisms: Insights from structural analysis
-
DOI 10.1146/annurev.biochem.66.1.639
-
Sprang, S. R. G protein mechanisms: insights from structural analysis. Annu. Rev. Biochem. 66, 639-678 (1997). (Pubitemid 27274670)
-
(1997)
Annual Review of Biochemistry
, vol.66
, pp. 639-678
-
-
Sprang, S.R.1
-
129
-
-
0031012747
-
Pasteurella multocida toxin activates the inositol triphosphate signaling pathway in Xenopus oocytes via G(q)α-coupled phospholipase C-β1
-
DOI 10.1074/jbc.272.2.1268
-
Wilson, B. A., Zhu, X., Ho, M. & Lu, L. Pasteurella multocida toxin activates the inositol triphosphate signaling pathway in Xenopus oocytes via Gqα-coupled phospholipase C-β1. J. Biol. Chem. 272, 1268-1275 (1997). (Pubitemid 27034627)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.2
, pp. 1268-1275
-
-
Wilson, B.A.1
Zhu, X.2
Ho, M.3
Lu, L.4
-
130
-
-
34047276113
-
Modulation of host cell gene expression through activation of STAT transcription factors by Pasteurella multocida toxin
-
DOI 10.1074/jbc.M609018200
-
Orth, J. H., Aktories, K. & Kubatzky, K. F. Modulation of host cell gene expression through activation of STAT transcription factors by Pasteurella multocida toxin. J. Biol. Chem. 282, 3050-3057 (2007). (Pubitemid 47084349)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.5
, pp. 3050-3057
-
-
Orth, J.H.C.1
Aktories, K.2
Kubatzky, K.F.3
-
131
-
-
59749099895
-
Pasteurella multocida toxin activates Gβγ dimers of heterotrimeric G proteins
-
Preuss, I., Kurig, B., N?rnberg, B., Orth, J. H. & Aktories, K. Pasteurella multocida toxin activates Gβγ dimers of heterotrimeric G proteins. Cell. Signal. 21, 551-558 (2009).
-
(2009)
Cell. Signal.
, vol.21
, pp. 551-558
-
-
Preuss, I.1
Kurig, B.2
Nrnberg, B.3
Orth, J.H.4
Aktories, K.5
-
132
-
-
77957127483
-
Pasteurella multocida toxin is a potent activator of anti-apoptotic signalling pathways
-
Preuss, I., Hildebrand, D., Orth, J. H., Aktories, K. & Kubatzky, K. F. Pasteurella multocida toxin is a potent activator of anti-apoptotic signalling pathways. Cell. Microbiol. 12, 1174-1185 (2010).
-
(2010)
Cell. Microbiol.
, vol.12
, pp. 1174-1185
-
-
Preuss, I.1
Hildebrand, D.2
Orth, J.H.3
Aktories, K.4
Kubatzky, K.F.5
-
133
-
-
27744535465
-
12/13
-
DOI 10.1074/jbc.M507203200
-
Orth, J. H., Lang, S., Taniguchi, M. & Aktories, K. Pasteurella multocida toxin-induced activation of RhoA is mediated via two families of Gα proteins, Gαq and Gα12/13. J. Biol. Chem. 280, 36701-36707 (2005). (Pubitemid 41587748)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.44
, pp. 36701-36707
-
-
Orth, J.H.C.1
Lang, S.2
Taniguchi, M.3
Aktories, K.4
-
134
-
-
0025124554
-
Pasteurella multocida toxin: Potent mitogen for cultured fibroblasts
-
Rozengurt, E., Higgins, T., Chanter, N., Lax, A. J. & Staddon, J. M. Pasteurella multocida toxin: potent mitogen for cultured fibroblasts. Proc. Natl Acad. Sci. USA 87, 123-127 (1990).
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 123-127
-
-
Rozengurt, E.1
Higgins, T.2
Chanter, N.3
Lax, A.J.4
Staddon, J.M.5
-
135
-
-
0025804531
-
2+ in Swiss 3T3 cells
-
Staddon, J. M. et al. Pasteurella multocida toxin, a potent mitogen, increases inositol 1,4,5-triphosphate and mobilizes Ca2+ in swiss 3T3 cells. J. Biol. Chem. 266, 4840-4847 (1991). (Pubitemid 21909431)
-
(1991)
Journal of Biological Chemistry
, vol.266
, Issue.8
, pp. 4840-4847
-
-
Staddon, J.M.1
Barker, C.J.2
Murphy, A.C.3
Chanter, N.4
Lax, A.J.5
Michell, R.H.6
Rozengurt, E.7
-
136
-
-
0035830825
-
Pleiotropic effects of Pasteurella multocida toxin are mediated by Gq-dependent and -independent mechanisms Involvement of Gq but not G11
-
Zywietz, A., Gohla, A., Schmelz, M., Schultz, G. & Offermanns, S. Pleiotropic effects of Pasteurella multocida toxin are mediated by Gq-dependent and -independent mechanisms. Involvement of Gq but not G11. J. Biol. Chem. 276, 3840-3845 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3840-3845
-
-
Zywietz, A.1
Gohla, A.2
Schmelz, M.3
Schultz, G.4
Offermanns, S.5
-
137
-
-
0030891386
-
Localization of the glucosyltransferase activity of Clostridium difficile toxin B to the N-terminal part of the holotoxin
-
DOI 10.1074/jbc.272.17.11074
-
Hofmann, F., Busch, C., Prepens, U., Just, I. & Aktories, K. Localization of the glucosyltransferase activity of Clostridium difficile toxin B to the N-terminal part of the holotoxin. J. Biol. Chem. 272, 11074-11078 (1997). (Pubitemid 27184097)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.17
, pp. 11074-11078
-
-
Hofmann, F.1
Busch, C.2
Prepens, U.3
Just, I.4
Aktories, K.5
-
138
-
-
33745086500
-
Carbohydrate recognition by Clostridium difficile toxin A
-
DOI 10.1038/nsmb1084, PII N1084
-
Greco, A. et al. Carbohydrate recognition by Clostridium difficile toxin A. Nature Struct. Mol. Biol. 13, 460-461 (2006). (Pubitemid 43881588)
-
(2006)
Nature Structural and Molecular Biology
, vol.13
, Issue.5
, pp. 460-461
-
-
Greco, A.1
Ho, J.G.S.2
Lin, S.-J.3
Palcic, M.M.4
Rupnik, M.5
Ng, K.K.-S.6
-
139
-
-
34548472183
-
Auto-catalytic cleavage of Clostridium difficile toxins A and B depends on cysteine protease activity
-
DOI 10.1074/jbc.M703062200
-
Egerer, M., Giesemann, T., Jank, T., Satchell, K. J. & Aktories, K. Auto-catalytic cleavage of Clostridium difficile toxins A and B depends on a cysteine protease activity. J. Biol. Chem. 282, 25314-25321 (2007). (Pubitemid 47372781)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.35
, pp. 25314-25321
-
-
Egerer, M.1
Giesemann, T.2
Jank, T.3
Satchell, K.J.4
Aktories, K.5
-
140
-
-
79952418425
-
Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B
-
Genisyuerek, S. et al. Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B. Mol. Microbiol. 79, 1643-1654 (2011).
-
(2011)
Mol. Microbiol.
, vol.79
, pp. 1643-1654
-
-
Genisyuerek, S.1
-
141
-
-
33947502604
-
Autocatalytic cleavage of Clostridium difficile toxin B
-
DOI 10.1038/nature05622, PII NATURE05622
-
Reineke, J. et al. Autocatalytic cleavage of Clostridium difficile toxin B. Nature 446, 415-419 (2007). (Pubitemid 46474600)
-
(2007)
Nature
, vol.446
, Issue.7134
, pp. 415-419
-
-
Reineke, J.1
Tenzer, S.2
Rupnik, M.3
Koschinski, A.4
Hasselmayer, O.5
Schrattenholz, A.6
Schild, H.7
Von Eichel-Streiber, C.8
-
142
-
-
0242414631
-
Cellular uptake of Clostridium difficile toxin B. Translocation of the N-terminal catalytic domain into the cytosol of eukaryotic cells
-
DOI 10.1074/jbc.M307540200
-
Pfeifer, G. et al. Cellular uptake of Clostridium difficile toxin B: translocation of the N-terminal catalytic domain into the cytosol of eukaryotic cells. J. Biol. Chem. 278, 44535-44541 (2003). (Pubitemid 37377206)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.45
, pp. 44535-44541
-
-
Pfeifer, G.1
Schirmer, J.2
Leemhuis, J.3
Busch, C.4
Meyer, D.K.5
Aktories, K.6
Barth, H.7
-
143
-
-
77955782233
-
Structural organization of the functional domains of Clostridium difficile toxins A and B
-
Pruitt, R. N., Chambers, M. G., Ng, K. K., Ohi, M. D. & Lacy, D. B. Structural organization of the functional domains of Clostridium difficile toxins A and B. Proc. Natl Acad. Sci. USA 107, 13467-13472 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 13467-13472
-
-
Pruitt, R.N.1
Chambers, M.G.2
Ng, K.K.3
Ohi, M.D.4
Lacy, D.B.5
-
144
-
-
30444435782
-
Heterotrimeric G-proteins: A short history
-
DOI 10.1038/sj.bjp.0706405, PII 0706405
-
Milligan, G. & Kostenis, E. Heterotrimeric G-proteins: a short history. Br. J. Pharmacol. 147, S46-S55 (2006). (Pubitemid 43077261)
-
(2006)
British Journal of Pharmacology
, vol.147
, Issue.SUPPL. 1
-
-
Milligan, G.1
Kostenis, E.2
-
145
-
-
34247567041
-
Crystal structures reveal a thiol protease-like catalytic triad in the C-terminal region of Pasteurella multocida toxin
-
DOI 10.1073/pnas.0608197104
-
Kitadokoro, K. et al. Crystal structures reveal a thiol protease-like catalytic triad in the C-terminal region of Pasteurella multocida toxin. Proc. Natl Acad. Sci. USA 104, 5139-5144 (2007). (Pubitemid 47186189)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.12
, pp. 5139-5144
-
-
Kitadokoro, K.1
Kamitani, S.2
Miyazawa, M.3
Hanajima-Ozawa, M.4
Fukui, A.5
Miyake, M.6
Horiguchi, Y.7
-
146
-
-
42449139551
-
The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42
-
DOI 10.1042/BJ20071546
-
Upadhyay, A. et al. The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42. Biochem. J. 411, 485-493 (2008). (Pubitemid 351600733)
-
(2008)
Biochemical Journal
, vol.411
, Issue.3
, pp. 485-493
-
-
Upadhyay, A.1
Wu, H.-L.2
Williams, C.3
Field, T.4
Galyov, E.E.5
Van Den Elsen, J.M.H.6
Bagby, S.7
-
147
-
-
68249146082
-
Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics
-
Huang, Z. et al. Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics. Nature Struct. Mol. Biol. 16, 853-860 (2009).
-
(2009)
Nature Struct. Mol. Biol.
, vol.16
, pp. 853-860
-
-
Huang, Z.1
-
148
-
-
45249104707
-
Subversion of actin dynamics by EspM effectors of attaching and effacing bacterial pathogens
-
DOI 10.1111/j.1462-5822.2008.01136.x
-
Arbeloa, A. et al. Subversion of actin dynamics by EspM effectors of attaching and effacing bacterial pathogens. Cell. Microbiol. 10, 1429-1441 (2008). (Pubitemid 351837264)
-
(2008)
Cellular Microbiology
, vol.10
, Issue.7
, pp. 1429-1441
-
-
Arbeloa, A.1
Bulgin, R.R.2
Mackenzie, G.3
Shaw, R.K.4
Pallen, M.J.5
Crepin, V.F.6
Berger, C.N.7
Frankel, G.8
-
149
-
-
0025804295
-
Crystal structure of a cholera toxin-related heat-labile enterotoxin from E. coli
-
Sixma, T. K. et al. Crystal structure of a cholera toxin-related heat-labile enterotoxin from E. coli. Nature 351, 371-377 (1991). (Pubitemid 21896597)
-
(1991)
Nature
, vol.351
, Issue.6325
, pp. 371-377
-
-
Sixma, T.K.1
Pronk, S.E.2
Kalk, K.H.3
Wartna, E.S.4
Van Zanten, B.A.M.5
Witholt, B.6
Hol, W.G.J.7
-
150
-
-
0034685024
-
Deamidation of RhoA glutamine 63 by the Escherichia coli CNF1 toxin requires a short sequence of the GTPase switch 2 domain
-
DOI 10.1006/bbrc.1999.1904
-
Flatau, G., Landraud, L., Boquet, P., Bruzzone, M. & Munro, P. Deamidation of RhoA glutamine 63 by the Escherichia coli CNF1 toxin requires a short sequence of the GTPase switch 2 domain. Biochem. Biophys. Res. Commun. 267, 588-592 (2000). (Pubitemid 30076842)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.267
, Issue.2
, pp. 588-592
-
-
Flatau, G.1
Landraud, L.2
Boquet, P.3
Bruzzone, M.4
Munro, P.5
-
151
-
-
0030611230
-
Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho
-
Horiguchi, Y. et al. Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho. Proc. Natl Acad. Sci. USA 94, 11623-11626 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 11623-11626
-
-
Horiguchi, Y.1
-
152
-
-
0026524741
-
ADP-ribosylation of signal-transducing guanine nucleotide-binding proteins by pertussis toxin
-
Gierschik, P. ADP-ribosylation of signal-transducing guanine nucleotide-binding proteins by pertussis toxin. Curr. Top. Microbiol. Immunol. 175, 69-98 (1992).
-
(1992)
Curr. Top. Microbiol. Immunol.
, vol.175
, pp. 69-98
-
-
Gierschik, P.1
|