Toxin-Induced Necroptosis Is a Major Mechanism of Staphylococcus aureus Lung Damage

PLoS Pathogens

Volumn 11, Issue 4, 2015, Pages

  Kitur, Kipyegon ^a   Parker, Dane ^b   Nieto, Pamela ^c   Ahn, Danielle S ^b   Cohen, Taylor S ^b   Chung, Samuel ^b   Wachtel, Sarah ^b   Bueno, Susan ^c   Prince, Alice ^a,b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b Pontifical Catholic University of Chile ^*  (United States)

^c PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

CD200 RECEPTOR; CD86 ANTIGEN; CXCL1 CHEMOKINE; FLUORESCEIN ISOTHIOCYANATE; INFLAMMASOME; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; LACTATE DEHYDROGENASE; MIXED LINEAGE KINASE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; STAPHYLOCOCCUS TOXIN; TUMOR NECROSIS FACTOR; BACTERIAL TOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL VIRULENCE; CELL POPULATION; CHANNEL GATING; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY ASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE SILENCING; HUMAN; HUMAN CELL; IC50; INFLAMMATION; INTRACELLULAR SIGNALING; KUPFFER CELL; LUNG ALVEOLUS MACROPHAGE; LUNG INJURY; LUNG LAVAGE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MONOCYTE CULTURE; MOUSE; NECROPTOSIS; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA ANALYSIS; STAPHYLOCOCCAL PNEUMONIA; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL LINE; IMMUNOLOGY; METABOLISM; NECROSIS; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

MURINAE; MUS; STAPHYLOCOCCUS AUREUS;

ANIMALS; BACTERIAL TOXINS; BLOTTING, WESTERN; CELL LINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMANS; INFLAMMASOMES; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED C57BL; NECROSIS; PNEUMONIA, STAPHYLOCOCCAL; SIGNAL TRANSDUCTION;

EID: 84929494277     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004820     Document Type: Article

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