-
1
-
-
22044445517
-
Erlotinib in previously treated nonsmall-cell lung cancer
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T, Tan EH, Hirsh V, Thongprasert S, Campos D, Maoleekoonpiroj S, Smylie M, Martins R et al (2005) Erlotinib in previously treated nonsmall-cell lung cancer. N Engl J Med 353:123-132
-
(2005)
N Engl J Med
, vol.353
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
Tan, E.H.4
Hirsh, V.5
Thongprasert, S.6
Campos, D.7
Maoleekoonpiroj, S.8
Smylie, M.9
Martins, R.10
-
2
-
-
57349095906
-
The international epidemiology of lung cancer: Geographical distribution and secular trends
-
Youlden DR, Cramb SM, Baade PD (2008) The International Epidemiology of Lung Cancer: geographical distribution and secular trends. J Thorac Oncol 3:819-831
-
(2008)
J Thorac Oncol
, vol.3
, pp. 819-831
-
-
Youlden, D.R.1
Cramb, S.M.2
Baade, P.D.3
-
3
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61:69-90
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
4
-
-
84871511126
-
Deaths: Preliminary data for 2011
-
Hoyert DL XJ (2012) Deaths: preliminary data for 2011. Natl Vital Stat Rep 61:1-65
-
(2012)
Natl Vital Stat Rep
, vol.61
, pp. 1-65
-
-
Hoyert, D.1
-
5
-
-
0022509568
-
Higher risk of lung cancer in chronic obstructive pulmonary disease. A prospective, matched, controlled study
-
Skillrud DM, Offord KP, Miller RD (1986) Higher risk of lung cancer in chronic obstructive pulmonary disease. A prospective, matched, controlled study. Ann Intern Med 105:503-507
-
(1986)
Ann Intern Med
, vol.105
, pp. 503-507
-
-
Skillrud, D.M.1
Offord, K.P.2
Miller, R.D.3
-
7
-
-
22044431902
-
Relationship between reduced forced expiratory volume in one second and the risk of lung cancer: A systematic review and meta-analysis
-
Wasswa-Kintu S, Gan WQ, Man SF, Pare PD, Sin DD (2005) Relationship between reduced forced expiratory volume in one second and the risk of lung cancer: a systematic review and meta-analysis. Thorax 60:570-575
-
(2005)
Thorax
, vol.60
, pp. 570-575
-
-
Wasswa-Kintu, S.1
Gan, W.Q.2
Man, S.F.3
Pare, P.D.4
Sin, D.D.5
-
8
-
-
0035035768
-
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. Nhlbi/who global initiative for chronic obstructive lung disease (gold) workshop summary
-
Pauwels RA, Buist AS, Calverley PM, Jenkins CR, Hurd SS (2001) Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) workshop summary. Am J Respir Crit Care Med 163:1256-1276
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 1256-1276
-
-
Pauwels, R.A.1
Buist, A.S.2
Calverley, P.M.3
Jenkins, C.R.4
Hurd, S.S.5
-
9
-
-
18244410118
-
The pathogenesis of chronic obstructive pulmonary disease: Advances in the past 100 years
-
Shapiro SD, Ingenito EP (2005) The pathogenesis of chronic obstructive pulmonary disease: advances in the past 100 years. Am J Respir Cell Mol Biol 32:367-372
-
(2005)
Am J Respir Cell Mol Biol
, vol.32
, pp. 367-372
-
-
Shapiro, S.D.1
Ingenito, E.P.2
-
10
-
-
0029383641
-
The pathogenesis of emphysema: The elastase: Antielastase hypothesis 30 years later
-
Shapiro SD (1995) The pathogenesis of emphysema: the elastase: antielastase hypothesis 30 years later. Proc Assoc Am Physicians 107:346-352
-
(1995)
Proc Assoc am Physicians
, vol.107
, pp. 346-352
-
-
Shapiro, S.D.1
-
11
-
-
0017291178
-
Alpha-1-antitrypsin deficiency: A review; 1963-1975
-
Heidelberger KP (1976) Alpha-1-antitrypsin deficiency: a review; 1963-1975. Ann Clin Lab Sci 6:110-117
-
(1976)
Ann Clin Lab Sci
, vol.6
, pp. 110-117
-
-
Heidelberger, K.P.1
-
12
-
-
0002982441
-
Experimental emphysema: Its production with papain in normal and silicotic rats
-
Gross P, Pfitzer EA, Tolker E, Babyak MA, Kaschak M (1965) Experimental emphysema: its production with papain in normal and silicotic rats. Arch Environ Health 11:50-58
-
(1965)
Arch Environ Health
, vol.11
, pp. 50-58
-
-
Gross, P.1
Pfitzer, E.A.2
Tolker, E.3
Babyak, M.A.4
Kaschak, M.5
-
13
-
-
84864776533
-
Pathogenesis of chronic obstructive pulmonary disease
-
Tuder RM, Petrache I (2012) Pathogenesis of chronic obstructive pulmonary disease. J Clin Invest 122:2749-2755
-
(2012)
J Clin Invest
, vol.122
, pp. 2749-2755
-
-
Tuder, R.M.1
Petrache, I.2
-
14
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646-674
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
15
-
-
80053023874
-
International association for the study of lung can-cer/american thoracic society/european respiratory society: International multidisciplinary classification of lung adenocarcinoma: Executive summary
-
Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger K, Yatabe Y, Powell CA, Beer D, Riely G, Garg K et al (2011) International Association for the Study of Lung Can-cer/American Thoracic Society/European Respiratory Society: international multidisciplinary classification of lung adenocarcinoma: executive summary. Proc Am Thorac Soc 8:381-385
-
(2011)
Proc am Thorac Soc
, vol.8
, pp. 381-385
-
-
Travis, W.D.1
Brambilla, E.2
Noguchi, M.3
Nicholson, A.G.4
Geisinger, K.5
Yatabe, Y.6
Powell, C.A.7
Beer, D.8
Riely, G.9
Garg, K.10
-
17
-
-
0025317266
-
Ventilatory function and chronic mucus hypersecretion as predictors of death from lung cancer
-
Lange P, Nyboe J, Appleyard M, Jensen G, Schnohr P (1990) Ventilatory function and chronic mucus hypersecretion as predictors of death from lung cancer. Am Rev Respir Dis 141:613-617
-
(1990)
Am Rev Respir Dis
, vol.141
, pp. 613-617
-
-
Lange, P.1
Nyboe, J.2
Appleyard, M.3
Jensen, G.4
Schnohr, P.5
-
18
-
-
69249086981
-
Copd prevalence is increased in lung cancer, independent of age, sex and smoking history
-
Young RP, Hopkins RJ, Christmas T, Black PN, Metcalf P, Gamble GD (2009) COPD prevalence is increased in lung cancer, independent of age, sex and smoking history. Eur Respir J 34:380-386
-
(2009)
Eur Respir J
, vol.34
, pp. 380-386
-
-
Young, R.P.1
Hopkins, R.J.2
Christmas, T.3
Black, P.N.4
Metcalf, P.5
Gamble, G.D.6
-
20
-
-
37549021114
-
Assessing the relationship between lung cancer risk and emphysema detected on low-dose ct of the chest
-
de Torres JP, Bastarrika G, Wisnivesky JP, Alcaide AB, Campo A, Seijo LM, Pueyo JC, Villanueva A, Lozano MD, Montes U et al (2007) Assessing the relationship between lung cancer risk and emphysema detected on low-dose CT of the chest. Chest 132:1932-1938
-
(2007)
Chest
, vol.132
, pp. 1932-1938
-
-
De Torres, J.P.1
Bastarrika, G.2
Wisnivesky, J.P.3
Alcaide, A.B.4
Campo, A.5
Seijo, L.M.6
Pueyo, J.C.7
Villanueva, A.8
Lozano, M.D.9
Montes, U.10
-
21
-
-
52749088978
-
Association of radiographic emphysema and airflow obstruction with lung cancer
-
Wilson DO, Weissfeld JL, Balkan A, Schragin JG, Fuhrman CR, Fisher SN, Wilson J, Leader JK, Siegfried JM, Shapiro SD et al (2008) Association of radiographic emphysema and airflow obstruction with lung cancer. Am J Respir Crit Care Med 178:738-744
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 738-744
-
-
Wilson, D.O.1
Weissfeld, J.L.2
Balkan, A.3
Schragin, J.G.4
Fuhrman, C.R.5
Fisher, S.N.6
Wilson, J.7
Leader, J.K.8
Siegfried, J.M.9
Shapiro, S.D.10
-
22
-
-
84860556347
-
Emphysema scores predict death from copd and lung cancer
-
Zulueta JJ, Wisnivesky JP, Henschke CI, Yip R, Farooqi AO, McCauley DI, Chen M, Libby DM, Smith JP, Pasmantier MW et al (2012) Emphysema scores predict death from COPD and lung cancer. Chest 141:1216-1223
-
(2012)
Chest
, vol.141
, pp. 1216-1223
-
-
Zulueta, J.J.1
Wisnivesky, J.P.2
Henschke, C.I.3
Yip, R.4
Farooqi, A.O.5
Mc Cauley, D.I.6
Chen, M.7
Libby, D.M.8
Smith, J.P.9
Pasmantier, M.W.10
-
23
-
-
78650844739
-
Effect of emphysema on lung cancer risk in smokers: A computed tomography-based assessment
-
Li Y, Swensen SJ, Karabekmez LG, Marks RS, Stoddard SM, Jiang R, Worra JB, Zhang F, Midthun DE, de Andrade M et al (2011) Effect of emphysema on lung cancer risk in smokers: a computed tomography-based assessment. Cancer Prev Res (Phila) 4:43-50
-
(2011)
Cancer Prev Res (Phila)
, vol.4
, pp. 43-50
-
-
Li, Y.1
Swensen, S.J.2
Karabekmez, L.G.3
Marks, R.S.4
Stoddard, S.M.5
Jiang, R.6
Worra, J.B.7
Zhang, F.8
Midthun, D.E.9
De Andrade, M.10
-
24
-
-
78649806069
-
Are airflow obstruction and radiographic evidence of emphysema risk factors for lung cancer? A nested case-control study using quantitative emphysema analysis
-
Maldonado F, Bartholmai BJ, Swensen SJ, Midthun DE, Decker PA, Jett JR (2010) Are airflow obstruction and radiographic evidence of emphysema risk factors for lung cancer? A nested case-control study using quantitative emphysema analysis. Chest 138:1295-1302
-
(2010)
Chest
, vol.138
, pp. 1295-1302
-
-
Maldonado, F.1
Bartholmai, B.J.2
Swensen, S.J.3
Midthun, D.E.4
Decker, P.A.5
Jett, J.R.6
-
25
-
-
79959905759
-
Quantitative computed tomography analysis, airflow obstruction, and lung cancer in the pittsburgh lung screening study
-
Wilson DO, Leader JK, Fuhrman CR, Reilly JJ, Sciurba FC, Weissfeld JL (2011) Quantitative computed tomography analysis, airflow obstruction, and lung cancer in the Pittsburgh lung screening study. J Thorac Oncol 6:1200-1205
-
(2011)
J Thorac Oncol
, vol.6
, pp. 1200-1205
-
-
Wilson, D.O.1
Leader, J.K.2
Fuhrman, C.R.3
Reilly, J.J.4
Sciurba, F.C.5
Weissfeld, J.L.6
-
26
-
-
0016805047
-
Galen on cancer and related diseases
-
Reedy J (1975) Galen on cancer and related diseases. Clio Med 10:227-238
-
(1975)
Clio Med
, vol.10
, pp. 227-238
-
-
Reedy, J.1
-
27
-
-
0035901090
-
Inflammation and cancer: Back to virchow?
-
Balkwill F, Mantovani A (2001) Inflammation and cancer: back to Virchow? The Lancet 357:539-545
-
(2001)
The Lancet
, vol.357
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
28
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z (2002) Inflammation and cancer. Nature 420:860-867
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
29
-
-
84859071145
-
Cell recovery in bron- choalveolar lavage fluid in smokers is dependent on cumulative smoking history
-
Karimi R, Tornling G, Grunewald J, Eklund A, Skold CM (2012) Cell recovery in bron- choalveolar lavage fluid in smokers is dependent on cumulative smoking history. PLoS ONE 7:e34232
-
(2012)
Plos ONE
, vol.7
-
-
Karimi, R.1
Tornling, G.2
Grunewald, J.3
Eklund, A.4
Skold, C.M.5
-
30
-
-
0026683017
-
Bronchoal-veolar lavage cellularity. The distribution in normal volunteers
-
Merchant RK, Schwartz DA, Helmers RA, Dayton CS, Hunninghake GW (1992) Bronchoal-veolar lavage cellularity. The distribution in normal volunteers. Am Rev Respir Dis 146:448453
-
(1992)
Am Rev Respir Dis
, vol.146
, pp. 448-453
-
-
Merchant, R.K.1
Schwartz, D.A.2
Helmers, R.A.3
Dayton, C.S.4
Hunninghake, G.W.5
-
31
-
-
2942720573
-
The nature of small-airway obstruction in chronic obstructive pulmonary disease
-
Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, Cherniack RM, Rogers RM, Sciurba FC, Coxson HO et al (2004) The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 350:2645-2653
-
(2004)
N Engl J Med
, vol.350
, pp. 2645-2653
-
-
Hogg, J.C.1
Chu, F.2
Utokaparch, S.3
Woods, R.4
Elliott, W.M.5
Buzatu, L.6
Cherniack, R.M.7
Rogers, R.M.8
Sciurba, F.C.9
Coxson, H.O.10
-
32
-
-
15744363493
-
An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema
-
Grumelli S, Corry DB, Song LZ, Song L, Green L, Huh J, Hacken J, Espada R, Bag R, Lewis DE et al (2004) An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema. PLoS Med 1:e8
-
(2004)
Plos Med
, vol.1
-
-
Grumelli, S.1
Corry, D.B.2
Song, L.Z.3
Song, L.4
Green, L.5
Huh, J.6
Hacken, J.7
Espada, R.8
Bag, R.9
Lewis, D.E.10
-
33
-
-
34250197133
-
Cd8+ t cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice
-
Maeno T, Houghton AM, Quintero PA, Grumelli S, Owen CA, Shapiro SD (2007) CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice. J Immunol 178:8090-8096
-
(2007)
J Immunol
, vol.178
, pp. 8090-8096
-
-
Maeno, T.1
Houghton, A.M.2
Quintero, P.A.3
Grumelli, S.4
Owen, C.A.5
Shapiro, S.D.6
-
34
-
-
0030823772
-
Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
-
Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD (1997) Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 277:2002-2004
-
(1997)
Science
, vol.277
, pp. 2002-2004
-
-
Hautamaki, R.D.1
Kobayashi, D.K.2
Senior, R.M.3
Shapiro, S.D.4
-
35
-
-
0031011411
-
Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells
-
Mio T, Romberger DJ, Thompson AB, Robbins RA, Heires A, Rennard SI (1997) Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells. Am J Respir Crit Care Med 155:1770-1776
-
(1997)
Am J Respir Crit Care Med
, vol.155
, pp. 1770-1776
-
-
Mio, T.1
Romberger, D.J.2
Thompson, A.B.3
Robbins, R.A.4
Heires, A.5
Rennard, S.I.6
-
36
-
-
3543130200
-
Stat4 activation in smokers and patients with chronic obstructive pulmonary disease
-
Di Stefano A, Caramori G, Capelli A, Gnemmi I, Ricciardolo FL, Oates T, Donner CF, Chung KF, Barnes PJ, Adcock IM (2004) STAT4 activation in smokers and patients with chronic obstructive pulmonary disease. Eur Respir J 24:78-85
-
(2004)
Eur Respir J
, vol.24
, pp. 78-85
-
-
Di Stefano, A.1
Caramori, G.2
Capelli, A.3
Gnemmi, I.4
Ricciardolo, F.L.5
Oates, T.6
Donner, C.F.7
Chung, K.F.8
Barnes, P.J.9
Adcock, I.M.10
-
37
-
-
0017127862
-
The induction of emphysema with elastase. Ii. Changes in connective tissue
-
Kuhn C, Yu SY, Chraplyvy M, Linder HE, Senior RM (1976) The induction of emphysema with elastase. II. Changes in connective tissue. Lab Invest 34:372-380
-
(1976)
Lab Invest
, vol.34
, pp. 372-380
-
-
Kuhn, C.1
Yu, S.Y.2
Chraplyvy, M.3
Linder, H.E.4
Senior, R.M.5
-
38
-
-
70149110900
-
Smoking-dependent reprogramming of alveolar macrophage polarization: Implication for pathogenesis of chronic obstructive pulmonary disease
-
Shaykhiev R, Krause A, Salit J, Strulovici-Barel Y, Harvey BG, O'Connor TP, Crystal RG(2009) Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease. J Immunol 183:2867-2883
-
(2009)
J Immunol
, vol.183
, pp. 2867-2883
-
-
Shaykhiev, R.1
Krause, A.2
Salit, J.3
Strulovici-Barel, Y.4
Harvey, B.G.5
O’ Connor, T.P.6
Crystal, R.G.7
-
39
-
-
31344453943
-
Immune suppression in cancer: Effects on immune cells, mechanisms and future therapeutic intervention
-
Whiteside TL (2006) Immune suppression in cancer: effects on immune cells, mechanisms and future therapeutic intervention. Semin Cancer Biol 16:3-15
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 3-15
-
-
Whiteside, T.L.1
-
40
-
-
33749425534
-
Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on cd8+ t cells
-
Gallina G, Dolcetti L, Serafini P, De Santo C, Marigo I, Colombo MP, Basso G, Brombacher F, Borrello I, Zanovello P et al (2006) Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. J Clin Invest 116:2777-2790
-
(2006)
J Clin Invest
, vol.116
, pp. 2777-2790
-
-
Gallina, G.1
Dolcetti, L.2
Serafini, P.3
De Santo, C.4
Marigo, I.5
Colombo, M.P.6
Basso, G.7
Brombacher, F.8
Borrello, I.9
Zanovello, P.10
-
41
-
-
84862903106
-
Safety and activity of anti-pd-ll antibody in patients with advanced cancer
-
Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, Drake CG, Camacho LH, Kauh J, Odunsi K et al (2012) Safety and activity of anti-PD-Ll antibody in patients with advanced cancer. N Engl J Med 366:2455-2465
-
(2012)
N Engl J Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
Drake, C.G.7
Camacho, L.H.8
Kauh, J.9
Odunsi, K.10
-
42
-
-
30144443269
-
Paradoxical roles of the immune system during cancer development
-
de Visser KE, Eichten A, Coussens LM (2006) Paradoxical roles of the immune system during cancer development. Nat Rev Cancer 6:24-37
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 24-37
-
-
De Visser, K.E.1
Eichten, A.2
Coussens, L.M.3
-
43
-
-
0036839143
-
Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized m2 mononuclear phagocytes
-
Mantovani A, Sozzani S, Locati M, Allavena P, Sica A (2002) Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23:549-555
-
(2002)
Trends Immunol
, vol.23
, pp. 549-555
-
-
Mantovani, A.1
Sozzani, S.2
Locati, M.3
Allavena, P.4
Sica, A.5
-
44
-
-
79953328298
-
Tumor-associated neutrophils: New targets for cancer therapy
-
Gregory AD, Houghton AM (2011) Tumor-associated neutrophils: new targets for cancer therapy. Cancer Res 71:2411-2416
-
(2011)
Cancer Res
, vol.71
, pp. 2411-2416
-
-
Gregory, A.D.1
Houghton, A.M.2
-
45
-
-
7944223098
-
Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis
-
Sparmann A, Bar-Sagi D (2004) Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis. Cancer Cell 6:447-458
-
(2004)
Cancer Cell
, vol.6
, pp. 447-458
-
-
Sparmann, A.1
Bar-Sagi, D.2
-
46
-
-
33645518095
-
K-ras activation generates an inflammatory response in lung tumors
-
Ji H, Houghton AM, Mariani TJ, Perera S, Kim CB, Padera R, Tonon G, McNamara K, Mar-concini LA, Hezel A et al (2006) K-ras activation generates an inflammatory response in lung tumors. Oncogene 25:2105-2112
-
(2006)
Oncogene
, vol.25
, pp. 2105-2112
-
-
Ji, H.1
Houghton, A.M.2
Mariani, T.J.3
Perera, S.4
Kim, C.B.5
Padera, R.6
Tonon, G.7
Mc Namara, K.8
Mar-Concini, L.A.9
Hezel, A.10
-
47
-
-
84857992714
-
Predictive clinical outcome of the intratumoral cd66b-positive neutrophil-to-cd8-positive t-cell ratio in patients with resectable nonsmall cell lung cancer
-
Ilie M, Hofman V, Ortholan C, Bonnetaud C, Coelle C, Mouroux J, Hofman P (2012) Predictive clinical outcome of the intratumoral CD66b-positive neutrophil-to-CD8-positive T-cell ratio in patients with resectable nonsmall cell lung cancer. Cancer 118:1726-1737
-
(2012)
Cancer
, vol.118
, pp. 1726-1737
-
-
Ilie, M.1
Hofman, V.2
Ortholan, C.3
Bonnetaud, C.4
Coelle, C.5
Mouroux, J.6
Hofman, P.7
-
48
-
-
27544490377
-
Interleukin 17-producing cd4+ effector t cells develop via a lineage distinct from the t helper type 1 and 2 lineages
-
Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT(2005) Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 6:1123-1132
-
(2005)
Nat Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
49
-
-
70449651889
-
The role of interleukin-17 in the pathogenesis of rheumatoid arthritis
-
Gaffen SL (2009) The role of interleukin-17 in the pathogenesis of rheumatoid arthritis. Curr Rheumatol Rep 11:365-370
-
(2009)
Curr Rheumatol Rep
, vol.11
, pp. 365-370
-
-
Gaffen, S.L.1
-
50
-
-
68849084891
-
Structure and signalling in the il-17 receptor family
-
Gaffen SL (2009) Structure and signalling in the IL-17 receptor family. Nat Rev Immunol 9:556-567
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 556-567
-
-
Gaffen, S.L.1
-
51
-
-
79957613753
-
Il-17ra is required for ccl2 expression, macrophage recruitment, and emphysema in response to cigarette smoke
-
Chen K, Pociask DA, McAleer JP, Chan YR, Alcorn JF, Kreindler JL, Keyser MR, Shapiro SD, Houghton AM, Kolls JK et al (2011) IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke. PLoS ONE 6:e20333
-
(2011)
Plos ONE
, vol.6
-
-
Chen, K.1
Pociask, D.A.2
Mc Aleer, J.P.3
Chan, Y.R.4
Alcorn, J.F.5
Kreindler, J.L.6
Keyser, M.R.7
Shapiro, S.D.8
Houghton, A.M.9
Kolls, J.K.10
-
52
-
-
84856068597
-
Cigarette smoke induction of osteopontin (Spp1) mediates t(h)17 inflammation in human and experimental emphysema
-
Shan M, Yuan X, Song LZ, Roberts L, Zarinkamar N, Seryshev A, Zhang Y, Hilsenbeck S, Chang SH, Dong C et al (2012) Cigarette smoke induction of osteopontin (SPP1) mediates T(H)17 inflammation in human and experimental emphysema. Sci Transl Med 4:117ra119.
-
(2012)
Sci Transl Med 4:117Ra119
-
-
Shan, M.1
Yuan, X.2
Song, L.Z.3
Roberts, L.4
Zarinkamar, N.5
Seryshev, A.6
Zhang, Y.7
-
53
-
-
67650495415
-
Il-17 can promote tumor growth through an il-6-stat3 signaling pathway
-
Wang L, Yi T, Kortylewski M, Pardoll DM, Zeng D, Yu H (2009) IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J Exp Med 206:1457-1464
-
(2009)
J Exp Med
, vol.206
, pp. 1457-1464
-
-
Wang, L.1
Yi, T.2
Kortylewski, M.3
Pardoll, D.M.4
Zeng, D.5
Yu, H.6
-
54
-
-
70449530422
-
Restifo np, overwijk ww, dong c
-
Martin-Orozco N, Muranski P, Chung Y, Yang XO, Yamazaki T, Lu S, Hwu P, Restifo NP, Overwijk WW, Dong C (2009) T helper 17 cells promote cytotoxic T cell activation in tumor immunity. Immunity 31:787-798
-
(2009)
T Helper 17 Cells Promote Cytotoxic T Cell Activation in tumor immunity. Immunity
, vol.31
, pp. 787-798
-
-
Martin-Orozco, N.1
Muranski, P.2
Chung, Y.3
Yang, X.O.4
Yamazaki, T.5
Lu, S.6
Hwu, P.7
-
55
-
-
84883745262
-
An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy
-
Chung AS, Wu X, Zhuang G, Ngu H, Kasman I, Zhang J, Vernes JM, Jiang Z, Meng YG, Peale FV et al (2013) An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy. Nat Med 19:1114-1123
-
(2013)
Nat Med
, vol.19
, pp. 1114-1123
-
-
Chung, A.S.1
Wu, X.2
Zhuang, G.3
Ngu, H.4
Kasman, I.5
Zhang, J.6
Vernes, J.M.7
Jiang, Z.8
Meng, Y.G.9
Peale, F.V.10
-
56
-
-
17144445166
-
Myeloperoxidase-derived hypochlorous acid antagonizes the oxidative stress-mediated activation of iron regulatory protein 1
-
Mutze S, Hebling U, Stremmel W, Wang J, Arnhold J, Pantopoulos K, Mueller S (2003) Myeloperoxidase-derived hypochlorous acid antagonizes the oxidative stress-mediated activation of iron regulatory protein 1. J Biol Chem 278:40542-40549
-
(2003)
J Biol Chem
, vol.278
, pp. 40542-40549
-
-
Mutze, S.1
Hebling, U.2
Stremmel, W.3
Wang, J.4
Arnhold, J.5
Pantopoulos, K.6
Mueller, S.7
-
57
-
-
67649402187
-
The nrf2-antioxidant response element signaling pathway and its activation by oxidative stress
-
Nguyen T, Nioi P, Pickett CB (2009) The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. J Biol Chem 284:13291-13295
-
(2009)
J Biol Chem
, vol.284
, pp. 13291-13295
-
-
Nguyen, T.1
Nioi, P.2
Pickett, C.B.3
-
58
-
-
15244356847
-
Yamamoto m, petrache i, tuder rm, biswal s
-
Rangasamy T, Cho CY, Thimmulappa RK, Zhen L, Srisuma SS, Kensler TW, Yamamoto M, Petrache I, Tuder RM, Biswal S (2004) Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest 114:1248-1259
-
(2004)
Genetic Ablation of Nrf2 Enhances Susceptibility to cigarette Smoke-Induced Emphysema in Mice. J Clin Invest
, vol.114
, pp. 1248-1259
-
-
Rangasamy, T.1
Cho, C.Y.2
Thimmulappa, R.K.3
Zhen, L.4
Srisuma, S.S.5
Kensler, T.W.6
-
59
-
-
79955851027
-
Curcumin chemoprevention: The long road to clinical translation
-
Shureiqi I, Baron JA (2011) Curcumin chemoprevention: the long road to clinical translation. Cancer Prev Res (Phila) 4:296-298
-
(2011)
Cancer Prev Res (Phila)
, vol.4
, pp. 296-298
-
-
Shureiqi, I.1
Baron, J.A.2
-
60
-
-
84855409443
-
Modulation of the metabolism of airborne pollutants by glucora-phanin-rich and sulforaphane-rich broccoli sprout beverages in qidong, china
-
Kensler TW, Ng D, Carmella SG, Chen M, Jacobson LP, Munoz A, Egner PA, Chen JG, Qian GS, Chen TY et al (2012) Modulation of the metabolism of airborne pollutants by glucora-phanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China. Carcinogenesis 33:101-107
-
(2012)
Carcinogenesis
, vol.33
, pp. 101-107
-
-
Kensler, T.W.1
Ng, D.2
Carmella, S.G.3
Chen, M.4
Jacobson, L.P.5
Munoz, A.6
Egner, P.A.7
Chen, J.G.8
Qian, G.S.9
Chen, T.Y.10
-
61
-
-
79960060305
-
Oncogene-induced nrf2 transcription promotes ros detoxification and tumorigenesis
-
DeNicola GM, Karreth FA, Humpton TJ, Gopinathan A, Wei C, Frese K, Mangal D, Yu KH, Yeo CJ, Calhoun ES et al (2011) Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis. Nature 475:106-109.
-
(2011)
Nature
, vol.475
, pp. 106-109
-
-
Denicola, G.M.1
Karreth, F.A.2
Humpton, T.J.3
Gopinathan, A.4
Wei, C.5
Frese, K.6
Mangal, D.7
Yu, K.H.8
Yeo, C.J.9
Calhoun, E.S.10
-
62
-
-
77957796093
-
Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung
-
Satoh H, Moriguchi T, Taguchi K, Takai J, Maher JM, Suzuki T, Winnard PT Jr, Raman V, Ebina M, Nukiwa T et al (2010) Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung. Carcinogenesis 31:1833-1843.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1833-1843
-
-
Satoh, H.1
Moriguchi, T.2
Taguchi, K.3
Takai, J.4
Maher, J.M.5
Suzuki, T.6
Winnard, P.T.7
Ebina, M.8
Nukiwa, T.9
-
63
-
-
84864348569
-
Nrf2 and cancer: The good, the bad and the importance of context
-
Sporn MB, Liby KT (2012) NRF2 and cancer: the good, the bad and the importance of context. Nat Rev Cancer 12:564-571
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 564-571
-
-
Sporn, M.B.1
Liby, K.T.2
-
64
-
-
0026587438
-
Cigarette smoking and nicotine addiction
-
Benowitz NL (1992) Cigarette smoking and nicotine addiction. Med Clin North Am 76:415437
-
(1992)
Med Clin North Am
, vol.76
, pp. 415-437
-
-
Benowitz, N.L.1
-
65
-
-
33845348869
-
Xenobiotic-metabolizing enzymes in human lung
-
Zhang JY, Wang Y, Prakash C (2006) Xenobiotic-metabolizing enzymes in human lung. Curr Drug Metab 7:939-948
-
(2006)
Curr Drug Metab
, vol.7
, pp. 939-948
-
-
Zhang, J.Y.1
Wang, Y.2
Prakash, C.3
-
66
-
-
0020533852
-
Metabolism of polycyclic aromatic hydrocarbon derivatives to ultimate carcinogens during lipid peroxidation
-
Dix TA, Marnett LJ (1983) Metabolism of polycyclic aromatic hydrocarbon derivatives to ultimate carcinogens during lipid peroxidation. Science 221:77-79.
-
(1983)
Science
, vol.221
, pp. 77-79
-
-
Dix, T.A.1
Marnett, L.J.2
-
67
-
-
0036885798
-
Point: Myeloperoxidase - 463g - > a polymorphism and lung cancer risk
-
Feyler A, Voho A, Bouchardy C, Kuokkanen K, Dayer P, Hirvonen A, Benhamou S (2002)Point: myeloperoxidase - 463G - > a polymorphism and lung cancer risk. Cancer Epidemiol Biomarkers Prev 11:1550-1554
-
(2002)
Cancer Epidemiol Biomarkers Prev
, vol.11
, pp. 1550-1554
-
-
Feyler, A.1
Voho, A.2
Bouchardy, C.3
Kuokkanen, K.4
Dayer, P.5
Hirvonen, A.6
Benhamou, S.7
-
68
-
-
84875466646
-
Mechanistic links between copd and lung cancer
-
Houghton AM (2013) Mechanistic links between COPD and lung cancer. Nat Rev Cancer 13:233-245
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 233-245
-
-
Houghton, A.M.1
-
69
-
-
0035188727
-
How matrix metalloproteinases regulate cell behavior
-
Sternlicht MD, Werb Z (2001) How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol 17:463-516
-
(2001)
Annu Rev Cell Dev Biol
, vol.17
, pp. 463-516
-
-
Sternlicht, M.D.1
Werb, Z.2
-
70
-
-
33644545381
-
Tumour microenvironment—opinion: Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
-
Overall CM, Kleifeld O (2006) Tumour microenvironment—opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy. Nat Rev Cancer 6:227-239.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 227-239
-
-
Overall, C.M.1
Kleifeld, O.2
-
71
-
-
21844432918
-
Rac1b and reactive oxygen species mediate mmp-3-induced emt and genomic instability
-
Radisky DC, Levy DD, Littlepage LE, Liu H, Nelson CM, Fata JE, Leake D, Godden EL, Albertson DG, Nieto MA et al (2005) Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability. Nature 436:123-127.
-
(2005)
Nature
, vol.436
, pp. 123-127
-
-
Radisky, D.C.1
Levy, D.D.2
Littlepage, L.E.3
Liu, H.4
Nelson, C.M.5
Fata, J.E.6
Leake, D.7
Godden, E.L.8
Albertson, D.G.9
Nieto, M.A.10
-
72
-
-
0032031861
-
Reduced angiogenesis and tumor progression in gelatinase a-deficient mice
-
Itoh T, Tanioka M, Yoshida H, Yoshioka T, Nishimoto H, Itohara S (1998) Reduced angiogenesis and tumor progression in gelatinase A-deficient mice. Cancer Res 58:1048-1051.
-
(1998)
Cancer Res
, vol.58
, pp. 1048-1051
-
-
Itoh, T.1
Tanioka, M.2
Yoshida, H.3
Yoshioka, T.4
Nishimoto, H.5
Itohara, S.6
-
73
-
-
0036733629
-
Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms
-
Longo GM, Xiong W, Greiner TC, Zhao Y, Fiotti N, Baxter BT (2002) Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms. J Clin Invest 110:625-632.
-
(2002)
J Clin Invest
, vol.110
, pp. 625-632
-
-
Longo, G.M.1
Xiong, W.2
Greiner, T.C.3
Zhao, Y.4
Fiotti, N.5
Baxter, B.T.6
-
74
-
-
0029911694
-
Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice
-
Shipley JM, Wesselschmidt RL, Kobayashi DK, Ley TJ, Shapiro SD (1996) Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice. Proc Natl Acad Sci U S A 93:3942-3946
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 3942-3946
-
-
Shipley, J.M.1
Wesselschmidt, R.L.2
Kobayashi, D.K.3
Ley, T.J.4
Shapiro, S.D.5
-
75
-
-
0037435009
-
Loss of integrin alpha(V)beta6-mediated tgf-beta activation causes mmp12-depen-dent emphysema
-
Morris DG, Huang X, Kaminski N, Wang Y, Shapiro SD, Dolganov G, Glick A, Sheppard D (2003) Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-depen-dent emphysema. Nature 422:169-173
-
(2003)
Nature
, vol.422
, pp. 169-173
-
-
Morris, D.G.1
Huang, X.2
Kaminski, N.3
Wang, Y.4
Shapiro, S.D.5
Dolganov, G.6
Glick, A.7
Sheppard, D.8
-
76
-
-
30344464994
-
A distinctive alveolar macrophage activation state induced by cigarette smoking
-
Woodruff PG, Koth LL, Yang YH, Rodriguez MW, Favoreto S, Dolganov GM, Paquet AC, Erle DJ (2005) A distinctive alveolar macrophage activation state induced by cigarette smoking. Am J Respir Crit Care Med 172:1383-1392.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 1383-1392
-
-
Woodruff, P.G.1
Koth, L.L.2
Yang, Y.H.3
Rodriguez, M.W.4
Favoreto, S.5
Dolganov, G.M.6
Paquet, A.C.7
Erle, D.J.8
-
77
-
-
74049134939
-
Mmp12, lung function, and copd in high-risk populations
-
Hunninghake GM, Cho MH, Tesfaigzi Y, Soto-Quiros ME, Avila L, Lasky-Su J, Stidley C, Melen E, Soderhall C, Hallberg J et al (2009) MMP12, lung function, and COPD in high-risk populations. N Engl J Med 361:2599-2608
-
(2009)
N Engl J Med
, vol.361
, pp. 2599-2608
-
-
Hunninghake, G.M.1
Cho, M.H.2
Tesfaigzi, Y.3
Soto-Quiros, M.E.4
Avila, L.5
Lasky-Su, J.6
Stidley, C.7
Melen, E.8
Soderhall, C.9
Hallberg, J.10
-
78
-
-
33745700206
-
Macrophage elastase (Matrix metalloproteinase-12) suppresses growth of lung metastases
-
Houghton AM, Grisolano JL, Baumann ML, Kobayashi DK, Hautamaki RD, Nehring LC, Cornelius LA, Shapiro SD (2006) Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases. Cancer Res 66:6149-6155.
-
(2006)
Cancer Res
, vol.66
, pp. 6149-6155
-
-
Houghton, A.M.1
Grisolano, J.L.2
Baumann, M.L.3
Kobayashi, D.K.4
Hautamaki, R.D.5
Nehring, L.C.6
Cornelius, L.A.7
Shapiro, S.D.8
-
79
-
-
0032534596
-
Matrix metalloproteinases generate angiostatin: Effects on neovascularization
-
Cornelius LA, Nehring LC, Harding E, Bolanowski M, Welgus HG, Kobayashi DK, Pierce RA, Shapiro SD (1998) Matrix metalloproteinases generate angiostatin: effects on neovascularization. J Immunol 161:6845-6852
-
(1998)
J Immunol
, vol.161
, pp. 6845-6852
-
-
Cornelius, L.A.1
Nehring, L.C.2
Harding, E.3
Bolanowski, M.4
Welgus, H.G.5
Kobayashi, D.K.6
Pierce, R.A.7
Shapiro, S.D.8
-
80
-
-
0036010527
-
Release and activity of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 by alveolar macrophages from patients with chronic obstructive pulmonary disease
-
Russell RE, Culpitt SV, DeMatos C, Donnelly L, Smith M, Wiggins J, Barnes PJ (2002) Release and activity of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 by alveolar macrophages from patients with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 26:602-609
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 602-609
-
-
Russell, R.E.1
Culpitt, S.V.2
Dematos, C.3
Donnelly, L.4
Smith, M.5
Wiggins, J.6
Barnes, P.J.7
-
81
-
-
0036783727
-
Alveolar macrophage-mediated elastolysis: Roles of matrix metalloproteinases, cysteine, and serine proteases
-
Russell RE, Thorley A, Culpitt SV, Dodd S, Donnelly LE, Demattos C, Fitzgerald M, Barnes PJ (2002) Alveolar macrophage-mediated elastolysis: roles of matrix metalloproteinases, cysteine, and serine proteases. Am J Physiol Lung Cell Mol Physiol 283:L867-L873
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.283
-
-
Russell, R.E.1
Thorley, A.2
Culpitt, S.V.3
Dodd, S.4
Donnelly, L.E.5
Demattos, C.6
Fitzgerald, M.7
Barnes, P.J.8
-
82
-
-
0141449964
-
Matrilysin-dependent elastolysis by human macrophages
-
Filippov S, Caras I, Murray R, Matrisian LM, Chapman HA Jr, Shapiro S, Weiss SJ (2003)Matrilysin-dependent elastolysis by human macrophages. J Exp Med 198:925-935
-
(2003)
J Exp Med
, vol.198
, pp. 925-935
-
-
Filippov, S.1
Caras, I.2
Murray, R.3
Matrisian, L.M.4
Chapman, H.A.5
Shapiro, S.6
Weiss, S.J.7
-
83
-
-
79953331218
-
The role of matrix metalloproteinase-9 in cigarette smoke-induced emphysema
-
Atkinson JJ, Lutey BA, Suzuki Y, Toennies HM, Kelley DG, Kobayashi DK, Ijem WG, Deslee G, Moore CH, Jacobs ME et al (2011) The role of matrix metalloproteinase-9 in cigarette smoke-induced emphysema. Am J Respir Crit Care Med 183:876-884
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 876-884
-
-
Atkinson, J.J.1
Lutey, B.A.2
Suzuki, Y.3
Toennies, H.M.4
Kelley, D.G.5
Kobayashi, D.K.6
Ijem, W.G.7
Deslee, G.8
Moore, C.H.9
Acobs, M.E.10
-
84
-
-
0000391746
-
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
-
Bergers G, Brekken R, McMahon G, Vu TH, Itoh T, Tamaki K, Tanzawa K, Thorpe P, Itohara S, Werb Z et al (2000) Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat Cell Biol 2:737-744
-
(2000)
Nat Cell Biol
, vol.2
, pp. 737-744
-
-
Bergers, G.1
Brekken, R.2
Mc Mahon, G.3
Vu, T.H.4
Itoh, T.5
Tamaki, K.6
Tanzawa, K.7
Thorpe, P.8
Itohara, S.9
Werb, Z.10
-
85
-
-
0034721666
-
Mmp-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
-
Coussens LM, Tinkle CL, Hanahan D, Werb Z (2000) MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell 103:481-490
-
(2000)
Cell
, vol.103
, pp. 481-490
-
-
Coussens, L.M.1
Tinkle, C.L.2
Hanahan, D.3
Werb, Z.4
-
86
-
-
22344437713
-
Processing of vegf-a by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors
-
Lee S, Jilani SM, Nikolova GV, Carpizo D, Iruela-Arispe ML (2005) Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors. J Cell Biol 169:681-691
-
(2005)
J Cell Biol
, vol.169
, pp. 681-691
-
-
Lee, S.1
Jilani, S.M.2
Nikolova, G.V.3
Carpizo, D.4
Iruela-Arispe, M.L.5
-
87
-
-
33747602354
-
Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis
-
Nozawa H, Chiu C, Hanahan D (2006) Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis. Proc Natl Acad Sci U S A 103:1249312498
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 12493-12498
-
-
Nozawa, H.1
Chiu, C.2
Hanahan, D.3
-
88
-
-
0026461115
-
Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema
-
D'Armiento J, Dalal SS, Okada Y, Berg RA, Chada K (1992) Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema. Cell 71:955-961
-
(1992)
Cell
, vol.71
, pp. 955-961
-
-
D’ Armiento, J.1
Dalal, S.S.2
Okada, Y.3
Berg, R.A.4
Chada, K.5
-
89
-
-
0036501372
-
The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function
-
Joos L, He JQ, Shepherdson MB, Connett JE, Anthonisen NR, Pare PD, Sandford AJ (2002)The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function. Hum Mol Genet 11:569-576
-
(2002)
Hum Mol Genet
, vol.11
, pp. 569-576
-
-
Joos, L.1
He, J.Q.2
Shepherdson, M.B.3
Connett, J.E.4
Anthonisen, N.R.5
Pare, P.D.6
Sandford, A.J.7
-
90
-
-
34147220392
-
Mediators of vascular remodelling co-opted for sequential steps in lung metastasis
-
Gupta GP, Nguyen DX, Chiang AC, Bos PD, Kim JY, Nadal C, Gomis RR, Manova-Todor-ova K, Massague J (2007) Mediators of vascular remodelling co-opted for sequential steps in lung metastasis. Nature 446:765-770
-
(2007)
Nature
, vol.446
, pp. 765-770
-
-
Gupta, G.P.1
Nguyen, D.X.2
Chiang, A.C.3
Bos, P.D.4
Kim, J.Y.5
Nadal, C.6
Gomis, R.R.7
Massague, J.8
-
91
-
-
69249228553
-
Adamts1 and mmp1 proteolytically engage egf-like ligands in an osteolytic signaling cascade for bone metastasis
-
Lu X, Wang Q, Hu G, Van Poznak C, Fleisher M, Reiss M, Massague J, Kang Y (2009) ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis. Genes Dev 23:1882-1894
-
(2009)
Genes Dev
, vol.23
, pp. 1882-1894
-
-
Lu, X.1
Wang, Q.2
Hu, G.3
Van Poznak, C.4
Fleisher, M.5
Reiss, M.6
Massague, J.7
Kang, Y.8
-
92
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, Giri DD, Viale A, Olshen AB, Gerald WL, Massague J (2005) Genes that mediate breast cancer metastasis to lung. Nature 436:518-524
-
(2005)
Nature
, vol.436
, pp. 518-524
-
-
Minn, A.J.1
Gupta, G.P.2
Siegel, P.M.3
Bos, P.D.4
Shu, W.5
Giri, D.D.6
Viale, A.7
Olshen, A.B.8
Gerald, W.L.9
Massague, J.10
-
93
-
-
33749350351
-
A cancer cell metalloprotease triad regulates the basement membrane transmigration program
-
Hotary K, Li XY, Allen E, Stevens SL, Weiss SJ (2006) A cancer cell metalloprotease triad regulates the basement membrane transmigration program. Genes Dev 20:2673-2686
-
(2006)
Genes Dev
, vol.20
, pp. 2673-2686
-
-
Hotary, K.1
Li, X.Y.2
Allen, E.3
Stevens, S.L.4
Weiss, S.J.5
-
94
-
-
2142784516
-
Mt1-mmp-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover
-
Holmbeck K, Bianco P, Caterina J, Yamada S, Kromer M, Kuznetsov SA, Mankani M, Robey PG, Poole AR, Pidoux I et al (1999) MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell99:81-92
-
(1999)
Cell
, vol.99
, pp. 81-92
-
-
Holmbeck, K.1
Bianco, P.2
Caterina, J.3
Yamada, S.4
Kromer, M.5
Kuznetsov, S.A.6
Mankani, M.7
Robey, P.G.8
Poole, A.R.9
Pidoux, I.10
-
95
-
-
0037192458
-
Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
-
Coussens LM, Fingleton B, Matrisian LM (2002) Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 295:2387-2392
-
(2002)
Science
, vol.295
, pp. 2387-2392
-
-
Coussens, L.M.1
Fingleton, B.2
Matrisian, L.M.3
-
96
-
-
0036716282
-
Strategies for mmp inhibition in cancer: Innovations for the post-trial era
-
Overall CM, Lopez-Otin C (2002) Strategies for MMP inhibition in cancer: innovations for the post-trial era. Nat Rev Cancer 2:657-672
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 657-672
-
-
Overall, C.M.1
Lopez-Otin, C.2
-
97
-
-
42249109450
-
Serine peptidases: Classification, structure and function
-
Page MJ, Di Cera E (2008) Serine peptidases: classification, structure and function. Cell Mol Life Sci 65:1220-1236
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 1220-1236
-
-
Page, M.J.1
Di Cera, E.2
-
98
-
-
0036168150
-
Dipeptidyl peptidase i activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis
-
Adkison AM, Raptis SZ, Kelley DG, Pham CT (2002) Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis. J Clin Invest 109:363-371
-
(2002)
J Clin Invest
, vol.109
, pp. 363-371
-
-
Adkison, A.M.1
Raptis, S.Z.2
Kelley, D.G.3
Pham, C.T.4
-
99
-
-
43049147575
-
The molecular aetiology of the serpinopathies
-
Davies MJ, Lomas DA (2008) The molecular aetiology of the serpinopathies. Int J Biochem Cell Biol 40:1273-1286
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 1273-1286
-
-
Davies, M.J.1
Lomas, D.A.2
-
100
-
-
0036882394
-
Serine protease mechanism and specificity
-
Hedstrom L (2002) Serine protease mechanism and specificity. Chem Rev 102:4501-4524
-
(2002)
Chem Rev
, vol.102
, pp. 4501-4524
-
-
Hedstrom, L.1
-
101
-
-
0017669252
-
The induction of pulmonary emphysema with human leukocyte elastase
-
Senior RM, Tegner H, Kuhn C, Ohlsson K, Starcher BC, Pierce JA (1977) The induction of pulmonary emphysema with human leukocyte elastase. Am Rev Respir Dis 116:469-475
-
(1977)
Am Rev Respir Dis
, vol.116
, pp. 469-475
-
-
Senior, R.M.1
Tegner, H.2
Kuhn, C.3
Ohlsson, K.4
Starcher, B.C.5
Pierce, J.A.6
-
102
-
-
0344413022
-
Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice
-
Shapiro SD, Goldstein NM, Houghton AM, Kobayashi DK, Kelley D, Belaaouaj A (2003) Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice. Am J Pathol163:2329-2335
-
(2003)
Am J Pathol
, vol.163
, pp. 2329-2335
-
-
Shapiro, S.D.1
Goldstein, N.M.2
Houghton, A.M.3
Kobayashi, D.K.4
Kelley, D.5
Belaaouaj, A.6
-
103
-
-
0022500794
-
Immunolocalization of elastase in human emphysematous lungs
-
Damiano VV, Tsang A, Kucich U, Abrams WR, Rosenbloom J, Kimbel P, Fallahnejad M, Weinbaum G (1986) Immunolocalization of elastase in human emphysematous lungs. J Clin Invest 78:482-493
-
(1986)
J Clin Invest
, vol.78
, pp. 482-493
-
-
Damiano, V.V.1
Tsang, A.2
Kucich, U.3
Abrams, W.R.4
Rosenbloom, J.5
Kimbel, P.6
Fallahnejad, M.7
Weinbaum, G.8
-
104
-
-
76249101753
-
Neutrophil elastase-mediated degradation of irs-1 accelerates lung tumor growth
-
Houghton AM, Rzymkiewicz DM, Ji H, Gregory AD, Egea EE, Metz HE, Stolz DB, Land SR, Marconcini LA, Kliment CR et al (2010) Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth. Nat Med 16:219-223
-
(2010)
Nat Med
, vol.16
, pp. 219-223
-
-
Houghton, A.M.1
Rzymkiewicz, D.M.2
Ji, H.3
Gregory, A.D.4
Egea, E.E.5
Metz, H.E.6
Stolz, D.B.7
Land, S.R.8
Marconcini, L.A.9
Kliment, C.R.10
-
105
-
-
84867407206
-
Clathrin pit-mediated endocyto-sis of neutrophil elastase and cathepsin g by cancer cells
-
Gregory AD, Hale P, Perlmutter DH, Houghton AM (2012) Clathrin pit-mediated endocyto-sis of neutrophil elastase and cathepsin G by cancer cells. J Biol Chem 287:35341-35350
-
(2012)
J Biol Chem
, vol.287
, pp. 35341-35350
-
-
Gregory, A.D.1
Hale, P.2
Perlmutter, D.H.3
Houghton, A.M.4
-
106
-
-
0033660171
-
Inhibition of vegf receptors causes lung cell apoptosis and emphysema
-
Kasahara Y, Tuder RM, Taraseviciene-Stewart L, Le Cras TD, Abman S, Hirth PK, Walten-berger J, Voelkel NF (2000) Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J Clin Invest 106:1311-1319
-
(2000)
J Clin Invest
, vol.106
, pp. 1311-1319
-
-
Kasahara, Y.1
Tuder, R.M.2
Taraseviciene-Stewart, L.3
Le Cras, T.D.4
Abman, S.5
Hirth, P.K.6
Walten-Berger, J.7
Voelkel, N.F.8
-
107
-
-
0038070219
-
Alveolar wall apoptosis causes lung destruction and emphysematous changes
-
Aoshiba K, Yokohori N, Nagai A (2003) Alveolar wall apoptosis causes lung destruction and emphysematous changes. Am J Respir Cell Mol Biol 28:555-562
-
(2003)
Am J Respir Cell Mol Biol
, vol.28
, pp. 555-562
-
-
Aoshiba, K.1
Yokohori, N.2
Nagai, A.3
-
108
-
-
18844434417
-
Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice
-
Petrache I, Natarajan V, Zhen L, Medler TR, Richter AT, Cho C, Hubbard WC, Berdyshev EV, Tuder RM (2005) Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. Nat Med 11:491-498
-
(2005)
Nat Med
, vol.11
, pp. 491-498
-
-
Petrache, I.1
Natarajan, V.2
Zhen, L.3
Medler, T.R.4
Richter, A.T.5
Cho, C.6
Hubbard, W.C.7
Berdyshev, E.V.8
Tuder, R.M.9
-
109
-
-
70349104210
-
Epithelial cell apoptosis causes acute lung injury masquerading as emphysema
-
Mouded M, Egea EE, Brown MJ, Hanlon SM, Houghton AM, Tsai LW, Ingenito EP, Shapiro SD (2009) Epithelial cell apoptosis causes acute lung injury masquerading as emphysema. Am J Respir Cell Mol Biol 41:407-414
-
(2009)
Am J Respir Cell Mol Biol
, vol.41
, pp. 407-414
-
-
Mouded, M.1
Egea, E.E.2
Brown, M.J.3
Hanlon, S.M.4
Houghton, A.M.5
Tsai, L.W.6
Ingenito, E.P.7
Shapiro, S.D.8
-
110
-
-
84881095514
-
Erlotinib resistance in lung cancer: Current progress and future perspectives
-
Tang J, Salama R, Gadgeel SM, Sarkar FH, Ahmad A (2013) Erlotinib resistance in lung cancer: current progress and future perspectives. Front Pharmacol 4:151980.
-
(2013)
Front Pharmacol
, vol.15
, Issue.1980
, pp. 4
-
-
Tang, J.1
Salama, R.2
Gadgeel, S.M.3
Sarkar, F.H.4
Ahmad, A.5
-
111
-
-
84944597412
-
-
Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease: a clinical trial. Nocturnal Oxygen Therapy Trial Group
-
Tang J, Salama R, Gadgeel SM, Sarkar FH, Ahmad A Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease: a clinical trial. Nocturnal Oxygen Therapy Trial Group. Ann Intern Med 93:391-398.
-
Ann Intern Med
, vol.93
, pp. 391-398
-
-
Tang, J.1
Salama, R.2
Gadgeel, S.M.3
Sarkar, F.H.4
Ahmad, A.5
-
112
-
-
79961108629
-
Reduced lung-cancer mortality with low-dose computed tomographic screening
-
Aberle DR, Adams AM, Berg CD, Black WC, Clapp JD, Fagerstrom RM, Gareen IF, Gatso-nis C, Marcus PM, Sicks JD (2011) Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med 365:395-409
-
(2011)
N Engl J Med
, vol.365
, pp. 395-409
-
-
Aberle, D.R.1
Adams, A.M.2
Berg, C.D.3
Black, W.C.4
Clapp, J.D.5
Fagerstrom, R.M.6
Gareen, I.F.7
Gatso-Nis, C.8
Marcus, P.M.9
Sicks, J.D.10
-
113
-
-
84874688661
-
American cancer society lung cancer screening guidelines
-
Wender R, Fontham ET, Barrera E Jr, Colditz GA, Church TR, Ettinger DS, Etzioni R, Flowers CR, Gazelle GS, Kelsey DK et al (2013) American Cancer Society lung cancer screening guidelines. CA Cancer J Clin 63:107-117
-
(2013)
CA Cancer J Clin
, vol.63
, pp. 107-117
-
-
Wender, R.1
Fontham, E.T.2
Barrera, E.3
Colditz, G.A.4
Church, T.R.5
Ettinger, D.S.6
Etzioni, R.7
Flowers, C.R.8
Gazelle, G.S.9
Kelsey, D.K.10
-
114
-
-
34047193053
-
Inhaled corticosteroids and risk of lung cancer among patients with chronic obstructive pulmonary disease
-
Parimon T, Chien JW, Bryson CL, McDonell MB, Udris EM, Au DH (2007) Inhaled corticosteroids and risk of lung cancer among patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 175:712-719
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 712-719
-
-
Parimon, T.1
Chien, J.W.2
Bryson, C.L.3
Mc Donell, M.B.4
Udris, E.M.5
Au, D.H.6
-
115
-
-
33847172367
-
Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease
-
Calverley PM, Anderson JA, Celli B, Ferguson GT, Jenkins C, Jones PW, Yates JC, Vestbo J (2007) Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med 356:775-789
-
(2007)
N Engl J Med
, vol.356
, pp. 775-789
-
-
Calverley, P.M.1
Erson, J.A.2
Celli, B.3
Ferguson, G.T.4
Jenkins, C.5
Jones, P.W.6
Yates, J.C.7
Vestbo, J.8
-
116
-
-
62349138124
-
The cox-2/pge2 pathway: Key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
-
Greenhough A, Smartt HJ, Moore AE, Roberts HR, Williams AC, Paraskeva C, Kaidi A (2009) The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment. Carcinogenesis 30:377-386
-
(2009)
Carcinogenesis
, vol.30
, pp. 377-386
-
-
Greenhough, A.1
Smartt, H.J.2
Moore, A.E.3
Roberts, H.R.4
Williams, A.C.5
Paraskeva, C.6
Kaidi, A.7
-
117
-
-
0034901568
-
Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage i non-small cell lung cancer
-
Khuri FR, Wu H, Lee JJ, Kemp BL, Lotan R, Lippman SM, Feng L, Hong WK, Xu XC (2001) Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer. Clin Cancer Res 7:861-867
-
(2001)
Clin Cancer Res
, vol.7
, pp. 861-867
-
-
Khuri, F.R.1
Wu, H.2
Lee, J.J.3
Kemp, B.L.4
Lotan, R.5
Lippman, S.M.6
Feng, L.7
Hong, W.K.8
Xu, X.C.9
-
118
-
-
79960098447
-
Lung cancer chemoprevention with celecoxib in former smokers
-
Mao JT, Roth MD, Fishbein MC, Aberle DR, Zhang ZF, Rao JY, Tashkin DP, Goodglick L, Holmes EC, Cameron RB et al (2011) Lung cancer chemoprevention with celecoxib in former smokers. Cancer Prev Res (Phila) 4:984-993
-
(2011)
Cancer Prev Res (Phila)
, vol.4
, pp. 984-993
-
-
Mao, J.T.1
Roth, M.D.2
Fishbein, M.C.3
Aberle, D.R.4
Zhang, Z.F.5
Rao, J.Y.6
Tashkin, D.P.7
Goodglick, L.8
Holmes, E.C.9
Cameron, R.B.10
-
119
-
-
79957876607
-
Oral iloprost improves endobronchial dysplasia in former smokers
-
Keith RL, Blatchford PJ, Kittelson J, Minna JD, Kelly K, Massion PP, Franklin WA, Mao J, Wilson DO, Merrick DT et al (2011) Oral iloprost improves endobronchial dysplasia in former smokers. Cancer Prev Res (Phila) 4:793-802
-
(2011)
Cancer Prev Res (Phila)
, vol.4
, pp. 793-802
-
-
Keith, R.L.1
Blatchford, P.J.2
Kittelson, J.3
Minna, J.D.4
Kelly, K.5
Massion, P.P.6
Franklin, W.A.7
Mao, J.8
Wilson, D.O.9
Merrick, D.T.10
|