IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Chen, Kong ^a   Pociask, Derek A ^a   McAleer, Jeremy P ^a   Chan, Yvonne R ^b   Alcorn, John F ^b   Kreindler, James L ^c   Keyser, Matthew R ^d   Shapiro, Steven D ^b   Houghton, A McGarry ^b   Kolls, Jay K ^a   Zheng, Mingquan ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^d DNASTAR Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CIGARETTE SMOKE; GELATINASE B; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 17 RECEPTOR A; MACROPHAGE ELASTASE; MONOCYTE CHEMOTACTIC PROTEIN 1; UNCLASSIFIED DRUG; IL17RA PROTEIN, HUMAN; IMMUNOLOGICAL ADJUVANT; STROMELYSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHUS MUCOSA; CELL DIFFERENTIATION; CONTROLLED STUDY; EPITHELIUM CELL; EXPOSURE; FEMALE; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; IN VITRO STUDY; IN VIVO STUDY; LUNG EMPHYSEMA; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; TH1 CELL; TH17 CELL; WILD TYPE; ANIMAL; BRONCHUS; CYTOLOGY; EMPHYSEMA; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; LUNG LAVAGE; MACROPHAGE; METABOLISM; MUCOSA; SEQUENCE ANALYSIS; SMOKE; TOBACCO; TRANSCRIPTION INITIATION;

MUS;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; BRONCHI; BRONCHOALVEOLAR LAVAGE; CELL DIFFERENTIATION; CHEMOKINE CCL2; EMPHYSEMA; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MACROPHAGES; MATRIX METALLOPROTEINASE 12; MATRIX METALLOPROTEINASE 3; MICE; MUCOUS MEMBRANE; RECEPTORS, ARYL HYDROCARBON; RECEPTORS, INTERLEUKIN-17; SEQUENCE ANALYSIS, RNA; SMOKE; TH17 CELLS; TOBACCO; TRANSCRIPTIONAL ACTIVATION;

EID: 79957613753     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020333     Document Type: Article

References (38)

1. Lee G, Walser TC, Dubinett SM, (2009) Chronic inflammation, chronic obstructive pulmonary disease, and lung cancer. Curr Opin Pulm Med 15: 303-307.
2. Hogg JC, (2005) Infection and COPD. Exp Lung Res 31 (Suppl 1): 72-73.
3. Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, et al. (2004) The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 350: 2645-2653.
4. Di SA, Caramori G, Gnemmi I, Contoli M, Vicari C, et al. (2009) T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients. Clin Exp Immunol 157: 316-324.
5. Majori M, Corradi M, Caminati A, Cacciani G, Bertacco S, et al. (1999) Predominant TH1 cytokine pattern in peripheral blood from subjects with chronic obstructive pulmonary disease. J Allergy Clin Immunol 103: 458-462.
6. Barczyk A, Pierzchala W, Kon OM, Cosio B, Adcock IM, et al. (2006) Cytokine production by bronchoalveolar lavage T lymphocytes in chronic obstructive pulmonary disease. J Allergy Clin Immunol 117: 1484-1492.
7. Hodge G, Nairn J, Holmes M, Reynolds PN, Hodge S, (2007) Increased intracellular T helper 1 proinflammatory cytokine production in peripheral blood, bronchoalveolar lavage and intraepithelial T cells of COPD subjects. Clin Exp Immunol 150: 22-29.
8. Elias JA, Kang MJ, Crothers K, Homer R, Lee CG, (2006) State of the art. Mechanistic heterogeneity in chronic obstructive pulmonary disease: insights from transgenic mice. Proc Am Thorac Soc 3: 494-498.
9. Shan M, Cheng HF, Song LZ, Roberts L, Green L, et al. (2009) Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema. Sci Transl Med 1: 4ra10.
10. Palmer MT, Weaver CT, (2010) Autoimmunity: increasing suspects in the CD4+ T cell lineup. Nat Immunol 11: 36-40.
11. Veldhoen M, Hirota K, Westendorf AM, Buer J, Dumoutier L, et al. (2008) The aryl hydrocarbon receptor links T(H)17-cell-mediated autoimmunity to environmental toxins. Nature 453: 106-109.
12. Eustace A, Smyth LJ, Mitchell L, Williamson K, Plumb J, et al. (2010) Identification of Cells Expressing Interleukin-17A and F in the Lungs of COPD Patients. Chest.
13. Doe C, Bafadhel M, Siddiqui S, Desai D, Mistry V, et al. (2010) Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD. Chest 138: 1140-1147.
14. Costenbader KH, Kim DJ, Peerzada J, Lockman S, Nobles-Knight D, et al. (2004) Cigarette smoking and the risk of systemic lupus erythematosus: a meta-analysis. Arthritis Rheum 50: 849-857.
15. Kallberg H, Ding B, Padyukov L, Bengtsson C, Ronnelid J, et al. (2010) Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke. Ann Rheum Dis.
16. Mahid SS, Minor KS, Soto RE, Hornung CA, Galandiuk S, (2006) Smoking and inflammatory bowel disease: a meta-analysis. Mayo Clin Proc 81: 1462-1471.
17. Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD, (1997) Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 277: 2002-2004.
18. Gebremichael A, Tullis K, Denison MS, Cheek JM, Pinkerton KE, (1996) Ah-receptor-dependent modulation of gene expression by aged and diluted sidestream cigarette smoke. Toxicol Appl Pharmacol 141: 76-83.
19. Kitamura M, Kasai A, (2007) Cigarette smoke as a trigger for the dioxin receptor-mediated signaling pathway. Cancer Lett 252: 184-194.
20. Kroening PR, Barnes TW, Pease L, Limper A, Kita H, et al. (2008) Cigarette smoke-induced oxidative stress suppresses generation of dendritic cell IL-12 and IL-23 through ERK-dependent pathways. J Immunol 181: 1536-1547.
21. Veldhoen M, Hirota K, Christensen J, O'Garra A, Stockinger B, (2009) Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells. J Exp Med 206: 43-49.
22. Aujla SJ, Chan YR, Zheng M, Fei M, Askew DJ, et al. (2008) IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat Med 14: 275-281.
23. McAllister F, Henry A, Kreindler JL, Dubin PJ, Ulrich L, et al. (2005) Role of IL-17A, IL-17F, and the IL-17 Receptor in Regulating Growth-Related Oncogene-{alpha} and Granulocyte Colony-Stimulating Factor in Bronchial Epithelium: Implications for Airway Inflammation in Cystic Fibrosis. J Immunol 175: 404-412.
24. Kreda SM, Gynn MC, Fenstermacher DA, Boucher RC, Gabriel SE, (2001) Expression and localization of epithelial aquaporins in the adult human lung. Am J Respir Cell Mol Biol 24: 224-234.
25. Avril-Delplanque A, Casal I, Castillon N, Hinnrasky J, Puchelle E, et al. (2005) Aquaporin-3 expression in human fetal airway epithelial progenitor cells. Stem Cells 23: 992-1001.
26. Yang XO, Chang SH, Park H, Nurieva R, Shah B, et al. (2008) Regulation of inflammatory responses by IL-17F. J Exp Med.
27. Park H, Li Z, Yang XO, Chang SH, Nurieva R, et al. (2005) A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 6: 1133-1141.
28. Lee SH, Goswami S, Grudo A, Song LZ, Bandi V, et al. (2007) Antielastin autoimmunity in tobacco smoking-induced emphysema. Nat Med 13: 567-569.
29. Maeno T, Houghton AM, Quintero PA, Grumelli S, Owen CA, et al. (2007) CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice. J Immunol 178: 8090-8096.
30. Hsu HC, Yang P, Wang J, Wu Q, Myers R, et al. (2008) Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat Immunol 9: 166-175.
31. Mitsdoerffer M, Lee Y, Jager A, Kim HJ, Korn T, et al. (2010) Proinflammatory T helper type 17 cells are effective B-cell helpers. Proc Natl Acad Sci U S A 107: 14292-14297.
32. Pridgeon C, Bugeon L, Donnelly L, Straschil U, Tudhope SJ, et al. (2011) Regulation of IL-17 in chronic inflammation in the human lung. Clin Sci (Lond).
33. Grumelli S, Corry DB, Song LZ, Song L, Green L, et al. (2004) An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema. PLoS Med 1: e8.
34. Chung Y, Chang SH, Martinez GJ, Yang XO, Nurieva R, et al. (2009) Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity 30: 576-587.
35. Sutton C, Brereton C, Keogh B, Mills KH, Lavelle EC, (2006) A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. J Exp Med 203: 1685-1691.
36. Hartupee J, Liu C, Novotny M, Li X, Hamilton T, (2007) IL-17 enhances chemokine gene expression through mRNA stabilization. J Immunol 179: 4135-4141.
37. Carp H, Janoff A, (1978) Possible mechanisms of emphysema in smokers. In vitro suppression of serum elastase-inhibitory capacity by fresh cigarette smoke and its prevention by antioxidants. Am Rev Respir Dis 118: 617-621.
38. Gray TE, Guzman K, Davis CW, Abdullah LH, Nettesheim P, (1996) Mucociliary differentiation of serially passaged normal human tracheobronchial epithelial cells. Am J Respir Cell Mol Biol 14: 104-112.