-
1
-
-
0014667395
-
Thymus and reproduction: Sex-linked dysgenesia of the gonad after neonatal thymectomy in mice
-
Y. Nishizuka, and T. Sakakura Thymus and reproduction: sex-linked dysgenesia of the gonad after neonatal thymectomy in mice Science 166 3906 1969 753 755
-
(1969)
Science
, vol.166
, Issue.3906
, pp. 753-755
-
-
Nishizuka, Y.1
Sakakura, T.2
-
2
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
S. Sakaguchi, N. Sakaguchi, M. Asano, M. Itoh, and M. Toda Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases J Immunol 155 3 1995 1151 1164
-
(1995)
J Immunol
, vol.155
, Issue.3
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
3
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25 + regulatory T cells
-
J.D. Fontenot, M.A. Gavin, and A.Y. Rudensky Foxp3 programs the development and function of CD4+CD25 + regulatory T cells Nat Immunol 4 4 2003 330 336
-
(2003)
Nat Immunol
, vol.4
, Issue.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
4
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
S. Hori, T. Nomura, and S. Sakaguchi Control of regulatory T cell development by the transcription factor Foxp3 Science 299 5609 2003 1057 1061
-
(2003)
Science
, vol.299
, Issue.5609
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
5
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
M.E. Brunkow, E.W. Jeffery, K.A. Hjerrild, and et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse Nat Genet 27 1 2001 68 73
-
(2001)
Nat Genet
, vol.27
, Issue.1
, pp. 68-73
-
-
Brunkow, M.E.1
Jeffery, E.W.2
Hjerrild, K.A.3
-
6
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
C.L. Bennett, J. Christie, F. Ramsdell, and et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3 Nat Genet 27 1 2001 20 21
-
(2001)
Nat Genet
, vol.27
, Issue.1
, pp. 20-21
-
-
Bennett, C.L.1
Christie, J.2
Ramsdell, F.3
-
7
-
-
0036346861
-
Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome
-
R.S. Wildin, S. Smyk-Pearson, and A.H. Filipovich Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome J Med Genet 39 8 2002 537 545
-
(2002)
J Med Genet
, vol.39
, Issue.8
, pp. 537-545
-
-
Wildin, R.S.1
Smyk-Pearson, S.2
Filipovich, A.H.3
-
8
-
-
33846485153
-
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
-
J.M. Kim, J.P. Rasmussen, and A.Y. Rudensky Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice Nat Immunol 8 2 2007 191 197
-
(2007)
Nat Immunol
, vol.8
, Issue.2
, pp. 191-197
-
-
Kim, J.M.1
Rasmussen, J.P.2
Rudensky, A.Y.3
-
9
-
-
84922588496
-
Regulatory T-cells in autoimmune diseases: Challenges, controversies and - Yet - unanswered questions
-
C.R. Grant, R. Liberal, G. Mieli-Vergani, D. Vergani, and M.S. Longhi Regulatory T-cells in autoimmune diseases: challenges, controversies and - yet - unanswered questions Autoimmun Rev 14 2 2015 105 116
-
(2015)
Autoimmun Rev
, vol.14
, Issue.2
, pp. 105-116
-
-
Grant, C.R.1
Liberal, R.2
Mieli-Vergani, G.3
Vergani, D.4
Longhi, M.S.5
-
10
-
-
43049174722
-
Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction
-
Q. Tang, J.Y. Adams, C. Penaranda, and et al. Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction Immunity 28 5 2008 687 697
-
(2008)
Immunity
, vol.28
, Issue.5
, pp. 687-697
-
-
Tang, Q.1
Adams, J.Y.2
Penaranda, C.3
-
11
-
-
0027517545
-
Phenotypically distinct subsets of CD4 + T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice
-
F. Powrie, M.W. Leach, S. Mauze, L.B. Caddle, and R.L. Coffman Phenotypically distinct subsets of CD4 + T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice Int Immunol 5 11 1993 1461 1471
-
(1993)
Int Immunol
, vol.5
, Issue.11
, pp. 1461-1471
-
-
Powrie, F.1
Leach, M.W.2
Mauze, S.3
Caddle, L.B.4
Coffman, R.L.5
-
12
-
-
84894038785
-
Foxp3(+) T(reg) cells in humoral immunity
-
J.B. Wing, and S. Sakaguchi Foxp3(+) T(reg) cells in humoral immunity Int Immunol 26 2 2014 61 69
-
(2014)
Int Immunol
, vol.26
, Issue.2
, pp. 61-69
-
-
Wing, J.B.1
Sakaguchi, S.2
-
13
-
-
84892448554
-
Regulatory T cells in cancer immunotherapy
-
H. Nishikawa, and S. Sakaguchi Regulatory T cells in cancer immunotherapy Curr Opin Immunol 27 2014 1 7
-
(2014)
Curr Opin Immunol
, vol.27
, pp. 1-7
-
-
Nishikawa, H.1
Sakaguchi, S.2
-
14
-
-
82755184094
-
Two modes of immune suppression by Foxp3(+) regulatory T cells under inflammatory or non-inflammatory conditions
-
T. Yamaguchi, J.B. Wing, and S. Sakaguchi Two modes of immune suppression by Foxp3(+) regulatory T cells under inflammatory or non-inflammatory conditions Semin Immunol 23 6 2011 424 430
-
(2011)
Semin Immunol
, vol.23
, Issue.6
, pp. 424-430
-
-
Yamaguchi, T.1
Wing, J.B.2
Sakaguchi, S.3
-
15
-
-
79955529454
-
Trans-endocytosis of CD80 and CD86: A molecular basis for the cell-extrinsic function of CTLA-4
-
O.S. Qureshi, Y. Zheng, K. Nakamura, and et al. Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4 Science 332 6029 2011 600 603
-
(2011)
Science
, vol.332
, Issue.6029
, pp. 600-603
-
-
Qureshi, O.S.1
Zheng, Y.2
Nakamura, K.3
-
16
-
-
53749094183
-
CTLA-4 control over Foxp3 + regulatory T cell function
-
K. Wing, Y. Onishi, P. Prieto-Martin, and et al. CTLA-4 control over Foxp3 + regulatory T cell function Science 322 5899 2008 271 275
-
(2008)
Science
, vol.322
, Issue.5899
, pp. 271-275
-
-
Wing, K.1
Onishi, Y.2
Prieto-Martin, P.3
-
17
-
-
84918576077
-
Regulatory T cells control antigen-specific expansion of Tfh cell number and humoral immune responses via the coreceptor CTLA-4
-
J.B. Wing, W. Ise, T. Kurosaki, and S. Sakaguchi Regulatory T cells control antigen-specific expansion of Tfh cell number and humoral immune responses via the coreceptor CTLA-4 Immunity 41 6 2014 1013 1025
-
(2014)
Immunity
, vol.41
, Issue.6
, pp. 1013-1025
-
-
Wing, J.B.1
Ise, W.2
Kurosaki, T.3
Sakaguchi, S.4
-
18
-
-
84918507355
-
The coinhibitory receptor CTLA-4 controls B cell responses by modulating T follicular helper, T follicular regulatory, and T regulatory cells
-
P.T. Sage, A.M. Paterson, S.B. Lovitch, and A.H. Sharpe The coinhibitory receptor CTLA-4 controls B cell responses by modulating T follicular helper, T follicular regulatory, and T regulatory cells Immunity 41 6 2014 1026 1039
-
(2014)
Immunity
, vol.41
, Issue.6
, pp. 1026-1039
-
-
Sage, P.T.1
Paterson, A.M.2
Lovitch, S.B.3
Sharpe, A.H.4
-
19
-
-
84907909000
-
Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4
-
H.S. Kuehn, W. Ouyang, B. Lo, and et al. Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4 Science 345 6204 2014 1623 1627
-
(2014)
Science
, vol.345
, Issue.6204
, pp. 1623-1627
-
-
Kuehn, H.S.1
Ouyang, W.2
Lo, B.3
-
20
-
-
84938070889
-
Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations
-
D. Schubert, C. Bode, R. Kenefeck, and et al. Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations Nat Med 20 12 2014 1410 1416
-
(2014)
Nat Med
, vol.20
, Issue.12
, pp. 1410-1416
-
-
Schubert, D.1
Bode, C.2
Kenefeck, R.3
-
21
-
-
84878734958
-
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
-
T. Yamaguchi, A. Kishi, M. Osaki, and et al. Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression Proc Natl Acad Sci USA 110 23 2013 E2116 E2125
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.23
, pp. E2116-E2125
-
-
Yamaguchi, T.1
Kishi, A.2
Osaki, M.3
-
22
-
-
33746228122
-
FOXP3 controls regulatory T cell function through cooperation with NFAT
-
Y. Wu, M. Borde, V. Heissmeyer, and et al. FOXP3 controls regulatory T cell function through cooperation with NFAT Cell 126 2 2006 375 387
-
(2006)
Cell
, vol.126
, Issue.2
, pp. 375-387
-
-
Wu, Y.1
Borde, M.2
Heissmeyer, V.3
-
23
-
-
36048978911
-
Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature
-
J.A. Hill, M. Feuerer, K. Tash, and et al. Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature Immunity 27 5 2007 786 800
-
(2007)
Immunity
, vol.27
, Issue.5
, pp. 786-800
-
-
Hill, J.A.1
Feuerer, M.2
Tash, K.3
-
24
-
-
84866533054
-
A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells
-
W. Fu, A. Ergun, T. Lu, and et al. A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells Nat Immunol 13 10 2012 972 980
-
(2012)
Nat Immunol
, vol.13
, Issue.10
, pp. 972-980
-
-
Fu, W.1
Ergun, A.2
Lu, T.3
-
25
-
-
84898025820
-
Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation
-
H. Morikawa, N. Ohkura, A. Vandenbon, and et al. Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation Proc Natl Acad Sci USA 111 14 2014 5289 5294
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.14
, pp. 5289-5294
-
-
Morikawa, H.1
Ohkura, N.2
Vandenbon, A.3
-
26
-
-
84901233628
-
Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells
-
A. Arvey, J. van der Veeken, R.M. Samstein, Y. Feng, J.A. Stamatoyannopoulos, and A.Y. Rudensky Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells Nat Immunol 15 6 2014 580 587
-
(2014)
Nat Immunol
, vol.15
, Issue.6
, pp. 580-587
-
-
Arvey, A.1
Van Der Veeken, J.2
Samstein, R.M.3
Feng, Y.4
Stamatoyannopoulos, J.A.5
Rudensky, A.Y.6
-
27
-
-
33847242598
-
Foxp3 occupancy and regulation of key target genes during T-cell stimulation
-
A. Marson, K. Kretschmer, G.M. Frampton, and et al. Foxp3 occupancy and regulation of key target genes during T-cell stimulation Nature 445 7130 2007 931 935
-
(2007)
Nature
, vol.445
, Issue.7130
, pp. 931-935
-
-
Marson, A.1
Kretschmer, K.2
Frampton, G.M.3
-
28
-
-
34247215187
-
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
-
M. Ono, H. Yaguchi, N. Ohkura, and et al. Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1 Nature 446 7136 2007 685 689
-
(2007)
Nature
, vol.446
, Issue.7136
, pp. 685-689
-
-
Ono, M.1
Yaguchi, H.2
Ohkura, N.3
-
29
-
-
80052023563
-
Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation
-
M. Beyer, Y. Thabet, R.U. Muller, and et al. Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation Nat Immunol 12 9 2011 898 907
-
(2011)
Nat Immunol
, vol.12
, Issue.9
, pp. 898-907
-
-
Beyer, M.1
Thabet, Y.2
Muller, R.U.3
-
30
-
-
33847153417
-
Foxp3-dependent programme of regulatory T-cell differentiation
-
M.A. Gavin, J.P. Rasmussen, J.D. Fontenot, and et al. Foxp3-dependent programme of regulatory T-cell differentiation Nature 445 7129 2007 771 775
-
(2007)
Nature
, vol.445
, Issue.7129
, pp. 771-775
-
-
Gavin, M.A.1
Rasmussen, J.P.2
Fontenot, J.D.3
-
31
-
-
84866975037
-
Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification
-
R.M. Samstein, A. Arvey, S.Z. Josefowicz, and et al. Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification Cell 151 1 2012 153 166
-
(2012)
Cell
, vol.151
, Issue.1
, pp. 153-166
-
-
Samstein, R.M.1
Arvey, A.2
Josefowicz, S.Z.3
-
32
-
-
17044393922
-
Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells
-
E. Bettelli, M. Dastrange, and M. Oukka Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells Proc Natl Acad Sci USA 102 14 2005 5138 5143
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.14
, pp. 5138-5143
-
-
Bettelli, E.1
Dastrange, M.2
Oukka, M.3
-
33
-
-
69549120242
-
Eos mediates Foxp3-dependent gene silencing in CD4 + regulatory T cells
-
F. Pan, H. Yu, E.V. Dang, and et al. Eos mediates Foxp3-dependent gene silencing in CD4 + regulatory T cells Science 325 5944 2009 1142 1146
-
(2009)
Science
, vol.325
, Issue.5944
, pp. 1142-1146
-
-
Pan, F.1
Yu, H.2
Dang, E.V.3
-
34
-
-
84866548843
-
Transcription factor Foxp3 and its protein partners form a complex regulatory network
-
D. Rudra, P. deRoos, A. Chaudhry, and et al. Transcription factor Foxp3 and its protein partners form a complex regulatory network Nat Immunol 13 10 2012 1010 1019
-
(2012)
Nat Immunol
, vol.13
, Issue.10
, pp. 1010-1019
-
-
Rudra, D.1
DeRoos, P.2
Chaudhry, A.3
-
35
-
-
84861424521
-
An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes
-
J. Darce, D. Rudra, L. Li, and et al. An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes Immunity 36 5 2012 731 741
-
(2012)
Immunity
, vol.36
, Issue.5
, pp. 731-741
-
-
Darce, J.1
Rudra, D.2
Li, L.3
-
36
-
-
84902332541
-
Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60
-
Y. Xiao, Y. Nagai, G. Deng, and et al. Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60 Cell Reports 7 5 2014 1471 1480
-
(2014)
Cell Reports
, vol.7
, Issue.5
, pp. 1471-1480
-
-
Xiao, Y.1
Nagai, Y.2
Deng, G.3
-
37
-
-
62649165369
-
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses
-
Y. Zheng, A. Chaudhry, A. Kas, and et al. Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses Nature 458 7236 2009 351 356
-
(2009)
Nature
, vol.458
, Issue.7236
, pp. 351-356
-
-
Zheng, Y.1
Chaudhry, A.2
Kas, A.3
-
38
-
-
38349095578
-
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
-
Y. Tone, K. Furuuchi, Y. Kojima, M.L. Tykocinski, M.I. Greene, and M. Tone Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer Nat Immunol 9 2 2008 194 202
-
(2008)
Nat Immunol
, vol.9
, Issue.2
, pp. 194-202
-
-
Tone, Y.1
Furuuchi, K.2
Kojima, Y.3
Tykocinski, M.L.4
Greene, M.I.5
Tone, M.6
-
39
-
-
70449706325
-
Runx proteins regulate Foxp3 expression
-
L. Bruno, L. Mazzarella, M. Hoogenkamp, and et al. Runx proteins regulate Foxp3 expression J Exp Med 206 11 2009 2329 2337
-
(2009)
J Exp Med
, vol.206
, Issue.11
, pp. 2329-2337
-
-
Bruno, L.1
Mazzarella, L.2
Hoogenkamp, M.3
-
40
-
-
80555139651
-
Critical role of Bcl11b in suppressor function of T regulatory cells and prevention of inflammatory bowel disease
-
J. Vanvalkenburgh, D.I. Albu, C. Bapanpally, and et al. Critical role of Bcl11b in suppressor function of T regulatory cells and prevention of inflammatory bowel disease J Exp Med 208 10 2011 2069 2081
-
(2011)
J Exp Med
, vol.208
, Issue.10
, pp. 2069-2081
-
-
Vanvalkenburgh, J.1
Albu, D.I.2
Bapanpally, C.3
-
41
-
-
84908123494
-
Continuous requirement for the TCR in regulatory T cell function
-
A.G. Levine, A. Arvey, W. Jin, and A.Y. Rudensky Continuous requirement for the TCR in regulatory T cell function Nat Immunol 15 11 2014 1070 1078
-
(2014)
Nat Immunol
, vol.15
, Issue.11
, pp. 1070-1078
-
-
Levine, A.G.1
Arvey, A.2
Jin, W.3
Rudensky, A.Y.4
-
42
-
-
78049240315
-
Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function
-
Y. Xiao, B. Li, Z. Zhou, W.W. Hancock, H. Zhang, and M.I. Greene Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function Curr Opin Immunol 22 5 2010 583 591
-
(2010)
Curr Opin Immunol
, vol.22
, Issue.5
, pp. 583-591
-
-
Xiao, Y.1
Li, B.2
Zhou, Z.3
Hancock, W.W.4
Zhang, H.5
Greene, M.I.6
-
43
-
-
77649225958
-
Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization
-
J. van Loosdregt, Y. Vercoulen, T. Guichelaar, and et al. Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization Blood 115 5 2010 965 974
-
(2010)
Blood
, vol.115
, Issue.5
, pp. 965-974
-
-
Van Loosdregt, J.1
Vercoulen, Y.2
Guichelaar, T.3
-
44
-
-
79952274915
-
Sirtuin-1 targeting promotes Foxp3 + T-regulatory cell function and prolongs allograft survival
-
U.H. Beier, L. Wang, T.R. Bhatti, and et al. Sirtuin-1 targeting promotes Foxp3 + T-regulatory cell function and prolongs allograft survival Mol Cell Biol 31 5 2011 1022 1029
-
(2011)
Mol Cell Biol
, vol.31
, Issue.5
, pp. 1022-1029
-
-
Beier, U.H.1
Wang, L.2
Bhatti, T.R.3
-
45
-
-
84875153425
-
Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-alpha in rheumatoid arthritis
-
H. Nie, Y. Zheng, R. Li, and et al. Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-alpha in rheumatoid arthritis Nat Med 19 3 2013 322 328
-
(2013)
Nat Med
, vol.19
, Issue.3
, pp. 322-328
-
-
Nie, H.1
Zheng, Y.2
Li, R.3
-
46
-
-
33748460087
-
Foxp3-dependent and -independent molecules specific for CD25+CD4 + natural regulatory T cells revealed by DNA microarray analysis
-
N. Sugimoto, T. Oida, K. Hirota, and et al. Foxp3-dependent and -independent molecules specific for CD25+CD4 + natural regulatory T cells revealed by DNA microarray analysis Int Immunol 18 8 2006 1197 1209
-
(2006)
Int Immunol
, vol.18
, Issue.8
, pp. 1197-1209
-
-
Sugimoto, N.1
Oida, T.2
Hirota, K.3
-
47
-
-
33947600584
-
Regulatory T cell development in the absence of functional Foxp3
-
W. Lin, D. Haribhai, L.M. Relland, and et al. Regulatory T cell development in the absence of functional Foxp3 Nat Immunol 8 4 2007 359 368
-
(2007)
Nat Immunol
, vol.8
, Issue.4
, pp. 359-368
-
-
Lin, W.1
Haribhai, D.2
Relland, L.M.3
-
48
-
-
84869148187
-
T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development
-
N. Ohkura, M. Hamaguchi, H. Morikawa, and et al. T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development Immunity 37 5 2012 785 799
-
(2012)
Immunity
, vol.37
, Issue.5
, pp. 785-799
-
-
Ohkura, N.1
Hamaguchi, M.2
Morikawa, H.3
-
49
-
-
84869872964
-
Novel Foxo1-dependent transcriptional programs control T(reg) cell function
-
W. Ouyang, W. Liao, C.T. Luo, and et al. Novel Foxo1-dependent transcriptional programs control T(reg) cell function Nature 491 7425 2012 554 559
-
(2012)
Nature
, vol.491
, Issue.7425
, pp. 554-559
-
-
Ouyang, W.1
Liao, W.2
Luo, C.T.3
-
50
-
-
84865369147
-
DNA methylation dynamics during in vivo differentiation of blood and skin stem cells
-
C. Bock, I. Beerman, W.H. Lien, and et al. DNA methylation dynamics during in vivo differentiation of blood and skin stem cells Mol Cell 47 4 2012 633 647
-
(2012)
Mol Cell
, vol.47
, Issue.4
, pp. 633-647
-
-
Bock, C.1
Beerman, I.2
Lien, W.H.3
-
51
-
-
69049107358
-
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
-
X. Zhou, S.L. Bailey-Bucktrout, L.T. Jeker, and et al. Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo Nat Immunol 10 9 2009 1000 1007
-
(2009)
Nat Immunol
, vol.10
, Issue.9
, pp. 1000-1007
-
-
Zhou, X.1
Bailey-Bucktrout, S.L.2
Jeker, L.T.3
-
52
-
-
84887512828
-
Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response
-
S.L. Bailey-Bucktrout, M. Martinez-Llordella, X. Zhou, and et al. Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response Immunity 39 5 2013 949 962
-
(2013)
Immunity
, vol.39
, Issue.5
, pp. 949-962
-
-
Bailey-Bucktrout, S.L.1
Martinez-Llordella, M.2
Zhou, X.3
-
53
-
-
77957371028
-
Stability of the regulatory T cell lineage in vivo
-
Y.P. Rubtsov, R.E. Niec, S. Josefowicz, and et al. Stability of the regulatory T cell lineage in vivo Science 329 5999 2010 1667 1671
-
(2010)
Science
, vol.329
, Issue.5999
, pp. 1667-1671
-
-
Rubtsov, Y.P.1
Niec, R.E.2
Josefowicz, S.3
-
54
-
-
84857416489
-
Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells
-
T. Miyao, S. Floess, R. Setoguchi, and et al. Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells Immunity 36 2 2012 262 275
-
(2012)
Immunity
, vol.36
, Issue.2
, pp. 262-275
-
-
Miyao, T.1
Floess, S.2
Setoguchi, R.3
-
55
-
-
66949171924
-
Functional delineation and differentiation dynamics of human CD4 + T cells expressing the FoxP3 transcription factor
-
M. Miyara, Y. Yoshioka, A. Kitoh, and et al. Functional delineation and differentiation dynamics of human CD4 + T cells expressing the FoxP3 transcription factor Immunity 30 6 2009 899 911
-
(2009)
Immunity
, vol.30
, Issue.6
, pp. 899-911
-
-
Miyara, M.1
Yoshioka, Y.2
Kitoh, A.3
-
56
-
-
34047174849
-
Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production
-
S.E. Allan, S.Q. Crome, N.K. Crellin, and et al. Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production Int Immunol 19 4 2007 345 354
-
(2007)
Int Immunol
, vol.19
, Issue.4
, pp. 345-354
-
-
Allan, S.E.1
Crome, S.Q.2
Crellin, N.K.3
-
57
-
-
0348223787
-
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25 + regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
W. Chen, W. Jin, N. Hardegen, and et al. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25 + regulatory T cells by TGF-beta induction of transcription factor Foxp3 J Exp Med 198 12 2003 1875 1886
-
(2003)
J Exp Med
, vol.198
, Issue.12
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
-
58
-
-
76749133610
-
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
-
Y. Zheng, S. Josefowicz, A. Chaudhry, X.P. Peng, K. Forbush, and A.Y. Rudensky Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate Nature 463 7282 2010 808 812
-
(2010)
Nature
, vol.463
, Issue.7282
, pp. 808-812
-
-
Zheng, Y.1
Josefowicz, S.2
Chaudhry, A.3
Peng, X.P.4
Forbush, K.5
Rudensky, A.Y.6
-
59
-
-
78149408519
-
Methylation matters: Binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells
-
J.K. Polansky, L. Schreiber, C. Thelemann, and et al. Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells J Mol Med 88 10 2010 1029 1040
-
(2010)
J Mol Med
, vol.88
, Issue.10
, pp. 1029-1040
-
-
Polansky, J.K.1
Schreiber, L.2
Thelemann, C.3
-
60
-
-
34447265236
-
CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: A role for DNA methylation
-
H.P. Kim, and W.J. Leonard CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation J Exp Med 204 7 2007 1543 1551
-
(2007)
J Exp Med
, vol.204
, Issue.7
, pp. 1543-1551
-
-
Kim, H.P.1
Leonard, W.J.2
-
61
-
-
70350451993
-
Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells
-
D. Rudra, T. Egawa, M.M. Chong, P. Treuting, D.R. Littman, and A.Y. Rudensky Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells Nat Immunol 10 11 2009 1170 1177
-
(2009)
Nat Immunol
, vol.10
, Issue.11
, pp. 1170-1177
-
-
Rudra, D.1
Egawa, T.2
Chong, M.M.3
Treuting, P.4
Littman, D.R.5
Rudensky, A.Y.6
-
62
-
-
80053130719
-
An essential role of the transcription factor GATA-3 for the function of regulatory T cells
-
Y. Wang, M.A. Su, and Y.Y. Wan An essential role of the transcription factor GATA-3 for the function of regulatory T cells Immunity 35 3 2011 337 348
-
(2011)
Immunity
, vol.35
, Issue.3
, pp. 337-348
-
-
Wang, Y.1
Su, M.A.2
Wan, Y.Y.3
-
63
-
-
84908401913
-
Function of a Foxp3 cis-element in protecting regulatory T cell identity
-
X. Li, Y. Liang, M. LeBlanc, C. Benner, and Y. Zheng Function of a Foxp3 cis-element in protecting regulatory T cell identity Cell 158 4 2014 734 748
-
(2014)
Cell
, vol.158
, Issue.4
, pp. 734-748
-
-
Li, X.1
Liang, Y.2
LeBlanc, M.3
Benner, C.4
Zheng, Y.5
-
64
-
-
84908403082
-
Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus
-
Y. Feng, A. Arvey, T. Chinen, J. van der Veeken, G. Gasteiger, and A.Y. Rudensky Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus Cell 158 4 2014 749 763
-
(2014)
Cell
, vol.158
, Issue.4
, pp. 749-763
-
-
Feng, Y.1
Arvey, A.2
Chinen, T.3
Van Der Veeken, J.4
Gasteiger, G.5
Rudensky, A.Y.6
-
65
-
-
79952534189
-
Regulation of chromatin by histone modifications
-
A.J. Bannister, and T. Kouzarides Regulation of chromatin by histone modifications Cell Res 21 3 2011 381 395
-
(2011)
Cell Res
, vol.21
, Issue.3
, pp. 381-395
-
-
Bannister, A.J.1
Kouzarides, T.2
-
66
-
-
58149214356
-
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4 + T cells
-
G. Wei, L. Wei, J. Zhu, and et al. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4 + T cells Immunity 30 1 2009 155 167
-
(2009)
Immunity
, vol.30
, Issue.1
, pp. 155-167
-
-
Wei, G.1
Wei, L.2
Zhu, J.3
-
67
-
-
67650090496
-
Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity
-
C. Schmidl, M. Klug, T.J. Boeld, and et al. Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity Genome Res 19 7 2009 1165 1174
-
(2009)
Genome Res
, vol.19
, Issue.7
, pp. 1165-1174
-
-
Schmidl, C.1
Klug, M.2
Boeld, T.J.3
-
68
-
-
45549098562
-
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR
-
S. Sauer, L. Bruno, A. Hertweck, and et al. T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR Proc Natl Acad Sci USA 105 22 2008 7797 7802
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.22
, pp. 7797-7802
-
-
Sauer, S.1
Bruno, L.2
Hertweck, A.3
-
69
-
-
84898022503
-
The enhancer and promoter landscape of human regulatory and conventional T-cell subpopulations
-
C. Schmidl, L. Hansmann, T. Lassmann, and et al. The enhancer and promoter landscape of human regulatory and conventional T-cell subpopulations Blood 123 17 2014 e68 e78
-
(2014)
Blood
, vol.123
, Issue.17
, pp. e68-e78
-
-
Schmidl, C.1
Hansmann, L.2
Lassmann, T.3
-
70
-
-
84922999148
-
The chromatin-modifying enzyme Ezh2 is critical for the maintenance of regulatory T cell identity after activation
-
M. DuPage, G. Chopra, J. Quiros, and et al. The chromatin-modifying enzyme Ezh2 is critical for the maintenance of regulatory T cell identity after activation Immunity 42 2 2015 227 238
-
(2015)
Immunity
, vol.42
, Issue.2
, pp. 227-238
-
-
DuPage, M.1
Chopra, G.2
Quiros, J.3
-
71
-
-
60349089645
-
Nucleosome positioning and gene regulation: Advances through genomics
-
C. Jiang, and B.F. Pugh Nucleosome positioning and gene regulation: advances through genomics Nat Rev Genet 10 3 2009 161 172
-
(2009)
Nat Rev Genet
, vol.10
, Issue.3
, pp. 161-172
-
-
Jiang, C.1
Pugh, B.F.2
-
72
-
-
84928581675
-
Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance
-
S. Yang, N. Fujikado, D. Kolodin, C. Benoist, and D. Mathis Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance Science 348 6234 2015 589 594
-
(2015)
Science
, vol.348
, Issue.6234
, pp. 589-594
-
-
Yang, S.1
Fujikado, N.2
Kolodin, D.3
Benoist, C.4
Mathis, D.5
-
73
-
-
84863619688
-
Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict
-
R.M. Samstein, S.Z. Josefowicz, A. Arvey, P.M. Treuting, and A.Y. Rudensky Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict Cell 150 1 2012 29 38
-
(2012)
Cell
, vol.150
, Issue.1
, pp. 29-38
-
-
Samstein, R.M.1
Josefowicz, S.Z.2
Arvey, A.3
Treuting, P.M.4
Rudensky, A.Y.5
-
74
-
-
79960453738
-
A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity
-
D. Haribhai, J.B. Williams, S. Jia, and et al. A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity Immunity 35 1 2011 109 122
-
(2011)
Immunity
, vol.35
, Issue.1
, pp. 109-122
-
-
Haribhai, D.1
Williams, J.B.2
Jia, S.3
-
75
-
-
84867899425
-
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3 + T reg cells
-
S1721
-
J.M. Weiss, A.M. Bilate, M. Gobert, and et al. Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3 + T reg cells J Exp Med 209 10 2012 1723 1742 S1721
-
(2012)
J Exp Med
, vol.209
, Issue.10
, pp. 1723-1742
-
-
Weiss, J.M.1
Bilate, A.M.2
Gobert, M.3
-
76
-
-
84867901322
-
Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo
-
S1711-1719
-
M. Yadav, C. Louvet, D. Davini, and et al. Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo J Exp Med 209 10 2012 1713 1722 S1711-1719
-
(2012)
J Exp Med
, vol.209
, Issue.10
, pp. 1713-1722
-
-
Yadav, M.1
Louvet, C.2
Davini, D.3
-
77
-
-
84907066418
-
Release of active TGF-beta1 from the latent TGF-beta1/GARP complex on T regulatory cells is mediated by integrin beta8
-
J.P. Edwards, A.M. Thornton, and E.M. Shevach Release of active TGF-beta1 from the latent TGF-beta1/GARP complex on T regulatory cells is mediated by integrin beta8 J Immunol 193 6 2014 2843 2849
-
(2014)
J Immunol
, vol.193
, Issue.6
, pp. 2843-2849
-
-
Edwards, J.P.1
Thornton, A.M.2
Shevach, E.M.3
-
78
-
-
37849009964
-
A two-step process for thymic regulatory T cell development
-
C.W. Lio, and C.S. Hsieh A two-step process for thymic regulatory T cell development Immunity 28 1 2008 100 111
-
(2008)
Immunity
, vol.28
, Issue.1
, pp. 100-111
-
-
Lio, C.W.1
Hsieh, C.S.2
-
79
-
-
84862814979
-
Selection of regulatory T cells in the thymus
-
C.S. Hsieh, H.M. Lee, and C.W. Lio Selection of regulatory T cells in the thymus Nat Rev Immunol 12 3 2012 157 167
-
(2012)
Nat Rev Immunol
, vol.12
, Issue.3
, pp. 157-167
-
-
Hsieh, C.S.1
Lee, H.M.2
Lio, C.W.3
-
80
-
-
77953415548
-
CD28 facilitates the generation of Foxp3(-) cytokine responsive regulatory T cell precursors
-
C.W. Lio, L.F. Dodson, C.M. Deppong, C.S. Hsieh, and J.M. Green CD28 facilitates the generation of Foxp3(-) cytokine responsive regulatory T cell precursors J Immunol 184 11 2010 6007 6013
-
(2010)
J Immunol
, vol.184
, Issue.11
, pp. 6007-6013
-
-
Lio, C.W.1
Dodson, L.F.2
Deppong, C.M.3
Hsieh, C.S.4
Green, J.M.5
-
81
-
-
13944260538
-
CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
-
X. Tai, M. Cowan, L. Feigenbaum, and A. Singer CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2 Nat Immunol 6 2 2005 152 162
-
(2005)
Nat Immunol
, vol.6
, Issue.2
, pp. 152-162
-
-
Tai, X.1
Cowan, M.2
Feigenbaum, L.3
Singer, A.4
-
82
-
-
84879601640
-
Foxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals
-
X. Tai, B. Erman, A. Alag, and et al. Foxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals Immunity 38 6 2013 1116 1128
-
(2013)
Immunity
, vol.38
, Issue.6
, pp. 1116-1128
-
-
Tai, X.1
Erman, B.2
Alag, A.3
-
83
-
-
65549123867
-
Natural and adaptive foxp3 + regulatory T cells: More of the same or a division of labor?
-
M.A. Curotto de Lafaille, and J.J. Lafaille Natural and adaptive foxp3 + regulatory T cells: more of the same or a division of labor? Immunity 30 5 2009 626 635
-
(2009)
Immunity
, vol.30
, Issue.5
, pp. 626-635
-
-
Curotto De Lafaille, M.A.1
Lafaille, J.J.2
-
84
-
-
85027947787
-
Induction of colonic regulatory T cells by indigenous Clostridium species
-
K. Atarashi, T. Tanoue, T. Shima, and et al. Induction of colonic regulatory T cells by indigenous Clostridium species Science 331 6015 2011 337 341
-
(2011)
Science
, vol.331
, Issue.6015
, pp. 337-341
-
-
Atarashi, K.1
Tanoue, T.2
Shima, T.3
-
85
-
-
84890564250
-
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
-
Y. Furusawa, Y. Obata, S. Fukuda, and et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells Nature 504 7480 2013 446 450
-
(2013)
Nature
, vol.504
, Issue.7480
, pp. 446-450
-
-
Furusawa, Y.1
Obata, Y.2
Fukuda, S.3
-
86
-
-
84890550163
-
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
-
N. Arpaia, C. Campbell, X. Fan, and et al. Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation Nature 504 7480 2013 451 455
-
(2013)
Nature
, vol.504
, Issue.7480
, pp. 451-455
-
-
Arpaia, N.1
Campbell, C.2
Fan, X.3
-
87
-
-
78149277909
-
How tolerogenic dendritic cells induce regulatory T cells
-
R.A. Maldonado, and U.H. von Andrian How tolerogenic dendritic cells induce regulatory T cells Adv Immunol 108 2010 111 165
-
(2010)
Adv Immunol
, vol.108
, pp. 111-165
-
-
Maldonado, R.A.1
Von Andrian, U.H.2
-
88
-
-
10344220512
-
CD25- T cells generate CD25+Foxp3 + regulatory T cells by peripheral expansion
-
M.A. Curotto de Lafaille, A.C. Lino, N. Kutchukhidze, and J.J. Lafaille CD25- T cells generate CD25+Foxp3 + regulatory T cells by peripheral expansion J Immunol 173 12 2004 7259 7268
-
(2004)
J Immunol
, vol.173
, Issue.12
, pp. 7259-7268
-
-
Curotto De Lafaille, M.A.1
Lino, A.C.2
Kutchukhidze, N.3
Lafaille, J.J.4
-
89
-
-
71749094333
-
Development of Foxp3(+) regulatory T cells is driven by the c-Rel enhanceosome
-
Q. Ruan, V. Kameswaran, Y. Tone, and et al. Development of Foxp3(+) regulatory T cells is driven by the c-Rel enhanceosome Immunity 31 6 2009 932 940
-
(2009)
Immunity
, vol.31
, Issue.6
, pp. 932-940
-
-
Ruan, Q.1
Kameswaran, V.2
Tone, Y.3
-
90
-
-
71749088574
-
Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor
-
M. Long, S.G. Park, I. Strickland, M.S. Hayden, and S. Ghosh Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor Immunity 31 6 2009 921 931
-
(2009)
Immunity
, vol.31
, Issue.6
, pp. 921-931
-
-
Long, M.1
Park, S.G.2
Strickland, I.3
Hayden, M.S.4
Ghosh, S.5
-
91
-
-
77749245828
-
C-Rel is crucial for the induction of Foxp3(+) regulatory CD4(+) T cells but not T(H)17 cells
-
A. Visekruna, M. Huber, A. Hellhund, and et al. c-Rel is crucial for the induction of Foxp3(+) regulatory CD4(+) T cells but not T(H)17 cells Eur J Immunol 40 3 2010 671 676
-
(2010)
Eur J Immunol
, vol.40
, Issue.3
, pp. 671-676
-
-
Visekruna, A.1
Huber, M.2
Hellhund, A.3
-
92
-
-
85027932757
-
Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis
-
T. Sekiya, I. Kashiwagi, R. Yoshida, and et al. Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis Nat Immunol 14 3 2013 230 237
-
(2013)
Nat Immunol
, vol.14
, Issue.3
, pp. 230-237
-
-
Sekiya, T.1
Kashiwagi, I.2
Yoshida, R.3
-
93
-
-
79953769170
-
The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4 + T cells
-
T. Sekiya, I. Kashiwagi, N. Inoue, and et al. The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4 + T cells Nat Commun 2 2011 269
-
(2011)
Nat Commun
, vol.2
, pp. 269
-
-
Sekiya, T.1
Kashiwagi, I.2
Inoue, N.3
-
94
-
-
84857989935
-
Nuclear receptor Nr4a1 modulates both regulatory T-cell (Treg) differentiation and clonal deletion
-
M.S. Fassett, W. Jiang, A.M. D'Alise, D. Mathis, and C. Benoist Nuclear receptor Nr4a1 modulates both regulatory T-cell (Treg) differentiation and clonal deletion Proc Natl Acad Sci USA 109 10 2012 3891 3896
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.10
, pp. 3891-3896
-
-
Fassett, M.S.1
Jiang, W.2
D'Alise, A.M.3
Mathis, D.4
Benoist, C.5
-
95
-
-
79958251745
-
T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse
-
A.E. Moran, K.L. Holzapfel, Y. Xing, and et al. T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse J Exp Med 208 6 2011 1279 1289
-
(2011)
J Exp Med
, vol.208
, Issue.6
, pp. 1279-1289
-
-
Moran, A.E.1
Holzapfel, K.L.2
Xing, Y.3
-
96
-
-
77953811224
-
Foxo proteins cooperatively control the differentiation of Foxp3 + regulatory T cells
-
W. Ouyang, O. Beckett, Q. Ma, J.H. Paik, R.A. DePinho, and M.O. Li Foxo proteins cooperatively control the differentiation of Foxp3 + regulatory T cells Nat Immunol 11 7 2010 618 627
-
(2010)
Nat Immunol
, vol.11
, Issue.7
, pp. 618-627
-
-
Ouyang, W.1
Beckett, O.2
Ma, Q.3
Paik, J.H.4
DePinho, R.A.5
Li, M.O.6
-
97
-
-
33845935950
-
IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3 + regulatory T cells
-
M.A. Burchill, J. Yang, C. Vogtenhuber, B.R. Blazar, and M.A. Farrar IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3 + regulatory T cells J Immunol 178 1 2007 280 290
-
(2007)
J Immunol
, vol.178
, Issue.1
, pp. 280-290
-
-
Burchill, M.A.1
Yang, J.2
Vogtenhuber, C.3
Blazar, B.R.4
Farrar, M.A.5
-
98
-
-
33747801470
-
IL-2 regulates FOXP3 expression in human CD4+CD25 + regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo
-
E. Zorn, E.A. Nelson, M. Mohseni, and et al. IL-2 regulates FOXP3 expression in human CD4+CD25 + regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo Blood 108 5 2006 1571 1579
-
(2006)
Blood
, vol.108
, Issue.5
, pp. 1571-1579
-
-
Zorn, E.1
Nelson, E.A.2
Mohseni, M.3
-
99
-
-
77957724587
-
The Ets-1 transcription factor controls the development and function of natural regulatory T cells
-
E. Mouly, K. Chemin, H.V. Nguyen, and et al. The Ets-1 transcription factor controls the development and function of natural regulatory T cells J Exp Med 207 10 2010 2113 2125
-
(2010)
J Exp Med
, vol.207
, Issue.10
, pp. 2113-2125
-
-
Mouly, E.1
Chemin, K.2
Nguyen, H.V.3
-
100
-
-
84879685794
-
BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis
-
R. Roychoudhuri, K. Hirahara, K. Mousavi, and et al. BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis Nature 498 7455 2013 506 510
-
(2013)
Nature
, vol.498
, Issue.7455
, pp. 506-510
-
-
Roychoudhuri, R.1
Hirahara, K.2
Mousavi, K.3
-
101
-
-
77955498891
-
Smad2 and Smad3 are redundantly essential for the TGF-beta-mediated regulation of regulatory T plasticity and Th1 development
-
T. Takimoto, Y. Wakabayashi, T. Sekiya, and et al. Smad2 and Smad3 are redundantly essential for the TGF-beta-mediated regulation of regulatory T plasticity and Th1 development J Immunol 185 2 2010 842 855
-
(2010)
J Immunol
, vol.185
, Issue.2
, pp. 842-855
-
-
Takimoto, T.1
Wakabayashi, Y.2
Sekiya, T.3
-
102
-
-
84866403123
-
Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut
-
S.M. Schlenner, B. Weigmann, Q. Ruan, Y. Chen, and H. von Boehmer Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut J Exp Med 209 9 2012 1529 1535
-
(2012)
J Exp Med
, vol.209
, Issue.9
, pp. 1529-1535
-
-
Schlenner, S.M.1
Weigmann, B.2
Ruan, Q.3
Chen, Y.4
Von Boehmer, H.5
-
103
-
-
44049087148
-
A critical function for TGF-beta signaling in the development of natural CD4+CD25+Foxp3 + regulatory T cells
-
Y. Liu, P. Zhang, J. Li, A.B. Kulkarni, S. Perruche, and W. Chen A critical function for TGF-beta signaling in the development of natural CD4+CD25+Foxp3 + regulatory T cells Nat Immunol 9 6 2008 632 640
-
(2008)
Nat Immunol
, vol.9
, Issue.6
, pp. 632-640
-
-
Liu, Y.1
Zhang, P.2
Li, J.3
Kulkarni, A.B.4
Perruche, S.5
Chen, W.6
-
104
-
-
84875458605
-
Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus
-
A. Toker, D. Engelbert, G. Garg, and et al. Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus J Immunol 190 7 2013 3180 3188
-
(2013)
J Immunol
, vol.190
, Issue.7
, pp. 3180-3188
-
-
Toker, A.1
Engelbert, D.2
Garg, G.3
-
105
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
M. Tahiliani, K.P. Koh, Y. Shen, and et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1 Science 324 5929 2009 930 935
-
(2009)
Science
, vol.324
, Issue.5929
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
-
106
-
-
84886860116
-
TET enzymes, TDG and the dynamics of DNA demethylation
-
R.M. Kohli, and Y. Zhang TET enzymes, TDG and the dynamics of DNA demethylation Nature 502 7472 2013 472 479
-
(2013)
Nature
, vol.502
, Issue.7472
, pp. 472-479
-
-
Kohli, R.M.1
Zhang, Y.2
-
107
-
-
84871069553
-
Epigenetic regulation by long noncoding RNAs
-
J.T. Lee Epigenetic regulation by long noncoding RNAs Science 338 6113 2012 1435 1439
-
(2012)
Science
, vol.338
, Issue.6113
, pp. 1435-1439
-
-
Lee, J.T.1
|