Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance

Science

Volumn 348, Issue 6234, 2015, Pages 589-594

  Yang, Siyoung ^a,b   Fujikado, Noriyuki ^a   Kolodin, Dmitriy ^a   Benoist, Christophe ^a,c   Mathis, Diane ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; AUTOIMMUNE REGULATOR PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTOME;

AGE; CELLS AND CELL COMPONENTS; GENE EXPRESSION; IMMUNE SYSTEM; PEPTIDE; PROTEIN; TOLERANCE;

ADULT; ARTICLE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; COMPARATIVE STUDY; CROSS PRESENTATION; DENDRITIC CELL; ENHANCER REGION; HEMATOPOIETIC STEM CELL; IMMUNOLOGICAL TOLERANCE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRE T LYMPHOCYTE; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY T LYMPHOCYTE; STROMA CELL; T CELL DEPLETION; ANIMAL; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; PHYSIOLOGY;

MUS;

ANIMALS; ANTIGENS, CD4; AUTOIMMUNITY; FORKHEAD TRANSCRIPTION FACTORS; MICE; MICE, KNOCKOUT; RECEPTORS, ANTIGEN, T-CELL; SELF TOLERANCE; T-LYMPHOCYTES, REGULATORY; TRANSCRIPTION FACTORS; TRANSCRIPTOME;

EID: 84928581675     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaa7017     Document Type: Article

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