The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells

Nature Communications

Volumn 2, Issue 1, 2011, Pages

  Sekiya, Takashi ^a   Kashiwagi, Ikkou ^a   Inoue, Naoko ^a   Morita, Rimpei ^a   Hori, Shohei ^b   Waldmann, Herman ^c   Rudensky, Alexander Y ^d   Ichinose, Hiroshi ^e   Metzger, Daniel ^f   Chambon, Pierre ^f   Yoshimura, Akihiko ^a,g  

^a KEIO UNIVERSITY   (Japan)

^b RIKEN Center for Integrative Medical Sciences   (Japan)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^f INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^g JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2; MESSENGER RNA; NUCLEAR RECEPTOR RELATED FACTOR 1; TRANSCRIPTION FACTOR FOXP3; CYTOKINE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; NR4A2 PROTEIN, MOUSE;

ANIMAL CELL CULTURE; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; COLITIS; CYTOKINE PRODUCTION; DISEASE EXACERBATION; ENZYME INHIBITION; EPIGENETICS; HISTONE MODIFICATION; HOMEOSTASIS AND REGULATION; IN VITRO STUDY; LAMINA PROPRIA; LEUKOCYTE; POLYMERASE CHAIN REACTION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; REGULATORY T LYMPHOCYTE; TH1 CELL; ANIMAL; CELL CULTURE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; MOUSE; TRANSGENIC MOUSE;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOKINES; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; MICE; MICE, TRANSGENIC; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 2; PROTEIN BINDING; T-LYMPHOCYTES, REGULATORY;

EID: 79953769170     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms1272     Document Type: Article

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