Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response

Immunity

Volumn 39, Issue 5, 2013, Pages 949-962

  Bailey Bucktrout, Samantha L ^a,e   Martinez Llordella, Marc ^a   Zhou, Xuyu ^b   Anthony, Bryan ^c   Rosenthal, Wendy ^a   Luche, Herve ^d   Fehling, Hans J ^d   Bluestone, Jeffrey A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INSTITUTE OF MICROBIOLOGY   (China)

^c WASHINGTON UNIVERSITY   (United States)

^d UNIVERSITY HOSPITAL ULM   (Germany)

^e PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; CD11B ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD45R ANTIGEN; CRE RECOMBINASE; FREUND ADJUVANT; GAMMA INTERFERON; GLYCOPROTEIN P 15095; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; LEUKOCYTE ANTIGEN; MYELIN; RED FLUORESCENT PROTEIN; STAT5 PROTEIN; TETRAMER; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; YELLOW FLUORESCENT PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; HYBRID PROTEIN; MOG(38-49) PEPTIDE, MOUSE; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; PEPTIDE FRAGMENT;

3' UNTRANSLATED REGION; ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; AUTOIMMUNITY; BACTERIAL ARTIFICIAL CHROMOSOME; CD4+ T LYMPHOCYTE; CELL EXPANSION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; EFFECTOR CELL; GENE LOCUS; GLIA CELL; IMMUNE RESPONSE; IMMUNOSTIMULATION; INFLAMMATION; INFLAMMATORY CELL; LEUKOCYTE; LOXP SITE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE SUBPOPULATION; MACROPHAGE; MAJOR HISTOCOMPATIBILITY COMPLEX; MICROGLIA; MOUSE; MYELOID DENDRITIC CELL; NONHUMAN; OLIGODENDROGLIA; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; STOP CODON; TRANSGENIC MOUSE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL LINEAGE; CENTRAL NERVOUS SYSTEM; DNA METHYLATION; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; GENE EXPRESSION REGULATION; GENETICS; GERMFREE ANIMAL; IMMUNOLOGY; LYMPH NODE; LYMPHOCYTE ACTIVATION; PHYSIOLOGY; REGULATORY SEQUENCE; REPORTER GENE;

ANIMALS; AUTOANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; CELL LINEAGE; CENTRAL NERVOUS SYSTEM; DNA METHYLATION; DOWN-REGULATION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GENES, REPORTER; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; PEPTIDE FRAGMENTS; RECEPTORS, INTERLEUKIN-2; RECOMBINANT FUSION PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; SPECIFIC PATHOGEN-FREE ORGANISMS; T-LYMPHOCYTES, REGULATORY;

EID: 84887512828     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2013.10.016     Document Type: Article

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