Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus

Journal of Immunology

Volumn 190, Issue 7, 2013, Pages 3180-3188

  Toker, Aras ^a   Engelbert, Dirk ^b   Garg, Garima ^a   Polansky, Julia K ^a   Floess, Stefan ^a   Miyao, Takahisa ^c   Baron, Udo ^d   Düber, Sandra ^a   Geffers, Robert ^a   Giehr, Pascal ^e   Schallenberg, Sonja ^f   Kretschmer, Karsten ^f   Olek, Sven ^d   Walter, Jörn ^e   Weiss, Siegfried ^a   Hori, Shohei ^c   Hamann, Alf ^b   Huehn, Jochen ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c RIKEN Center for Integrative Medical Sciences   (Japan)

^d SOFIA GmbH   (Germany)

^e SAARLAND UNIVERSITY   (Germany)

^f CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD24 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CYTOSINE; TRANSCRIPTION FACTOR FOXP3;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL MATURATION; CONTROLLED STUDY; DEMETHYLATION; DEVELOPMENTAL STAGE; GENE EXPRESSION; HYDROXYLATION; IMMUNOCOMPETENT CELL; LYMPHOCYTE DIFFERENTIATION; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN METHYLATION; PROTEIN MODIFICATION; REGULATORY T LYMPHOCYTE; THYMUS;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CPG ISLANDS; CYTOSINE; DNA METHYLATION; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GENE ORDER; MALE; MICE; PRECURSOR CELLS, T-LYMPHOID; T-LYMPHOCYTES, REGULATORY; THYMUS GLAND;

EID: 84875458605     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1203473     Document Type: Article

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