RASopathies: Unraveling mechanisms with animal models

DMM Disease Models and Mechanisms

Volumn 8, Issue 8, 2015, Pages 769-782

  Jindal, Granton A ^a,b   Goyal, Yogesh ^a,b   Burdine, Rebecca D ^b   Rauen, Katherine A ^c   Shvartsman, Stanislav Y ^a,b  

^a Princeton University   (United States)

^b PRINCETON UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Developmental disorders; Drosophila; Drug target; Mice; Ras MAPK; Zebrafish

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; RAS PROTEIN;

ANIMAL MODEL; BENIGN TUMOR; BONE DEFECT; BRAIN MALFORMATION; CARDIO FACIO CUTANEOUS SYNDROME; COGNITIVE DEFECT; CONGENITAL HEART MALFORMATION; COSTELLO SYNDROME; DEVELOPMENTAL DISORDER; DISEASE MODEL; DROSOPHILA; GENETIC ENGINEERING; GERMLINE MUTATION; HUMAN; LEGIUS SYNDROME; LEOPARD SYNDROME; MOUSE; NEUROFIBROMATOSIS TYPE 1; NONHUMAN; NOONAN SYNDROME; PHENOTYPE; PRIORITY JOURNAL; RASOPATHY; REVIEW; SIGNAL TRANSDUCTION; SKELETON MALFORMATION; ANIMAL; BIOLOGICAL MODEL; GENETICS; METABOLISM; MUTATION;

ANIMALIA; DANIO RERIO; MUS;

ANIMALS; DISEASE MODELS, ANIMAL; GENETIC ENGINEERING; HUMANS; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; MUTATION; RAS PROTEINS;

EID: 84939552575     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.020339     Document Type: Review

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