Genetic and Functional Studies Implicate Synaptic Overgrowth and Ring Gland cAMP/PKA Signaling Defects in the Drosophila melanogaster Neurofibromatosis-1 Growth Deficiency

PLoS Genetics

Volumn 9, Issue 11, 2013, Pages

  Walker, James A ^a   Gouzi, Jean Y ^a,d   Long, Jennifer B ^b   Huang, Sidong ^c,e   Maher, Robert C ^a   Xia, Hongjing ^a   Khalil, Kheyal ^a   Ray, Arjun ^a   Van Vactor, David ^b   Bernards, René ^c   Bernards, André ^a,e  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

^d BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING   (Greece)

^e Biomedical Sciences Research Centre Alexander Fleming ^*  (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOKINETIC HORMONE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CCKLR 17D1 GENE; CHROMOSOME 1; CHROMOSOME 2; CONNECTOR ENHANCER OF KSR GENE; CONTROLLED STUDY; DALK GENE; DROSOPHILA MELANOGASTER; GENE; GROWTH RETARDATION; JELLYBELLY GENE; NEUROFIBROMATOSIS; NEUROMUSCULAR SYNAPSE; NONHUMAN; RNA INTERFERENCE; SCHWANN CELL; SIGNAL TRANSDUCTION;

ANIMALS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DROSOPHILA MELANOGASTER; HUMANS; MEMORY DISORDERS; MUTATION; NEUROFIBROMATOSIS 1; NEUROMUSCULAR JUNCTION; RAS GTPASE-ACTIVATING PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION;

EID: 84888253172     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003958     Document Type: Article

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