Involvement of EphA2-mediated tyrosine phosphorylation of Shp2 in Shp2-regulated activation of extracellular signal-regulated kinase

Oncogene

Volumn 32, Issue 45, 2013, Pages 5292-5301

  Miura, K ^a   Wakayama, Y ^a   Tanino, M ^b   Orba, Y ^b   Sawa, H ^b   Hatakeyama, M ^c   Tanaka, S ^b   Sabe, H ^d   Mochizuki, N ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

cancer; EphA2; Erk; LEOPARD syndrome; Shp2

Indexed keywords

EPHRIN RECEPTOR A2; MESSENGER RNA; METHIONINE; MITOGEN ACTIVATED PROTEIN KINASE; PHENYLALANINE; PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE SHP 2; THREONINE; TYROSINE;

ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER GROWTH; CONTROLLED STUDY; ELECTROCARDIOGRAPHY; GENE MUTATION; GENE OVEREXPRESSION; GENITAL SYSTEM DISEASE; HEART EDEMA; HUMAN; HUMAN CELL; HYPERTELORISM; IMMUNOHISTOCHEMISTRY; LEOPARD SYNDROME; MUTANT; OBSTRUCTIVE AIRWAY DISEASE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WILD TYPE; ZEBRA FISH;

ANIMALS; EDEMA, CARDIAC; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GRB2 ADAPTOR PROTEIN; HEPATOCYTE GROWTH FACTOR; HUMANS; LEOPARD SYNDROME; NOONAN SYNDROME; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; RECEPTOR, EPHA2; SIGNAL TRANSDUCTION; ZEBRAFISH;

EID: 84887447303     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.571     Document Type: Article

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