Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I

Human Molecular Genetics

Volumn 20, Issue 20, 2011, Pages 3910-3924

  Wang, Weixi ^a   Nyman, Jeffry S ^a,b   Ono, Koichiro ^a   Stevenson, David A ^c   Yang, Xiangli ^a   Elefteriou, Florent ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b DEPARTMENT OF VETERANS AFFAIRS   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 2 ALPHA 1; CRE RECOMBINASE; MITOGEN ACTIVATED PROTEIN KINASE; NEUROFIBROMIN; RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DYSPLASIA; BONE MARROW; BONE MASS; CARTILAGE CELL; CELL COUNT; CONTROLLED STUDY; CORTICAL BONE; HUMAN; KYPHOSIS; LOSS OF FUNCTION MUTATION; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; MOUSE; NEUROFIBROMATOSIS; NEUROFIBROMATOSIS TYPE 1; NONHUMAN; OSTEOBLAST; OSTEOBLAST NUMBER; OSTEOCLASTOGENESIS; OSTEOIDOSIS; POROSITY; PRIORITY JOURNAL; SCOLIOSIS; SKELETON MALFORMATION; SKULL; STEM CELL; THORAX WALL; TRANSGENIC MOUSE; X RAY ANALYSIS;

ANIMALS; BONE AND BONES; BONE DISEASES, DEVELOPMENTAL; BONE REMODELING; CHONDROCYTES; COLLAGEN TYPE II; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; INTERVERTEBRAL DISC; LOVASTATIN; MICE; MICE, KNOCKOUT; NEUROFIBROMATOSIS 1; NEUROFIBROMIN 1; OSTEOBLASTS; OSTEOCYTES; OSTEOGENESIS; PHENOTYPE; POROSITY; PROMOTER REGIONS, GENETIC; RAS PROTEINS; RECOMBINATION, GENETIC; STEM CELLS;

MUS;

EID: 80053137997     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr310     Document Type: Article

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