-
1
-
-
0033605484
-
Epidemiology of neurofibromatosis type 1
-
Friedman, J.M. (1999) Epidemiology of neurofibromatosis type 1. Am. J. Med. Genet., 89, 1-6.
-
(1999)
Am. J. Med. Genet
, vol.89
, pp. 1-6
-
-
Friedman, J.M.1
-
2
-
-
0033605480
-
Plexiform neurofibromas
-
Korf, B.R. (1999) Plexiform neurofibromas. Am. J. Med. Genet., 89, 31-37.
-
(1999)
Am. J. Med. Genet
, vol.89
, pp. 31-37
-
-
Korf, B.R.1
-
3
-
-
0347985298
-
It takes two to tango: Mast cell and Schwann cell interactions in neurofibromas
-
Viskochil, D.H. (2003) It takes two to tango: Mast cell and Schwann cell interactions in neurofibromas. J. Clin. Invest., 112, 1791-1793.
-
(2003)
J. Clin. Invest
, vol.112
, pp. 1791-1793
-
-
Viskochil, D.H.1
-
4
-
-
0028885150
-
Optic pathway tumors in children: The effect of neurofibromatosis type 1 on clinical manifestations and natural history
-
Listernick, R., Darling, C., Greenwald, M., Strauss, L. and Charrow, J. (1995) Optic pathway tumors in children: The effect of neurofibromatosis type 1 on clinical manifestations and natural history. J. Pediatr. 127, 718-722.
-
(1995)
J. Pediatr
, vol.127
, pp. 718-722
-
-
Listernick, R.1
Darling, C.2
Greenwald, M.3
Strauss, L.4
Charrow, J.5
-
5
-
-
0028304193
-
Natural history of optic pathway tumors in children with neurofibromatosis type 1: A longitudinal study
-
Listernick, R., Charrow, J., Greenwald, M. and Mets, M. (1994) Natural history of optic pathway tumors in children with neurofibromatosis type 1: A longitudinal study. J. Pediatr., 125, 63-66.
-
(1994)
J. Pediatr
, vol.125
, pp. 63-66
-
-
Listernick, R.1
Charrow, J.2
Greenwald, M.3
Mets, M.4
-
6
-
-
0036192918
-
The WHO classification of tumors of the nervous system
-
Kleihues, P., Louis, D.N., Scheithauer, B.W., Rorke, L.B., Reifenberger, G., Burger, P.C. and Cavenee, W.K. (2002) The WHO classification of tumors of the nervous system. J. Neuropathol. Exp. Neurol., 61 215-225.
-
(2002)
J. Neuropathol. Exp. Neurol
, vol.61
, pp. 215-225
-
-
Kleihues, P.1
Louis, D.N.2
Scheithauer, B.W.3
Rorke, L.B.4
Reifenberger, G.5
Burger, P.C.6
Cavenee, W.K.7
-
7
-
-
0031044804
-
Optic pathway gliomas in children with neurofibromatosis 1: Consensus statement from the Nf1 Optic Pathway Glioma Task Force
-
Listernick, R., Louis, D.N., Packer, R.J. and Gutmann, D.H. (1997) Optic pathway gliomas in children with neurofibromatosis 1: Consensus statement from the Nf1 Optic Pathway Glioma Task Force. Ann. Neurol. 41, 143-149.
-
(1997)
Ann. Neurol
, vol.41
, pp. 143-149
-
-
Listernick, R.1
Louis, D.N.2
Packer, R.J.3
Gutmann, D.H.4
-
8
-
-
0037056366
-
Gliomas presenting after age 10 in individuals with neurofibromatosis type 1 (Nf1)
-
Gutmann, D.H., Rasmussen, S.A., Wolkenstein, P., MacCollin, M.M., Guha, A., Inskip, P.D., North, K.N., Poyhonen, M., Birch, P.H. and Friedman, J.M. (2002) Gliomas presenting after age 10 in individuals with neurofibromatosis type 1 (Nf1). Neurology, 59, 759-761.
-
(2002)
Neurology
, vol.59
, pp. 759-761
-
-
Gutmann, D.H.1
Rasmussen, S.A.2
Wolkenstein, P.3
MacCollin, M.M.4
Guha, A.5
Inskip, P.D.6
North, K.N.7
Poyhonen, M.8
Birch, P.H.9
Friedman, J.M.10
-
9
-
-
0141457247
-
Optic pathway gliomas in neurofibromatosis type 1: The effect of presenting symptoms on outcome
-
King, A., Listernick, R., Charrow, J., Piersall, L. and Gutmann, D.H. (2003) Optic pathway gliomas in neurofibromatosis type 1: The effect of presenting symptoms on outcome. Am. J. Med. Genet. A, 122, 95-99.
-
(2003)
Am. J. Med. Genet. A
, vol.122
, pp. 95-99
-
-
King, A.1
Listernick, R.2
Charrow, J.3
Piersall, L.4
Gutmann, D.H.5
-
10
-
-
1442275007
-
Neurofibromatosis type 1 and optic pathway gliomas: Follow-up of 54 patients
-
Thiagalingam, S., Flaherty, M., Billson, F. and North, K. (2004) Neurofibromatosis type 1 and optic pathway gliomas: Follow-up of 54 patients. Ophthalmology, 111, 568-577.
-
(2004)
Ophthalmology
, vol.111
, pp. 568-577
-
-
Thiagalingam, S.1
Flaherty, M.2
Billson, F.3
North, K.4
-
11
-
-
0036293742
-
Astrocyte-specific inactivation of the neurofibromatosis 1 gene (Nf1) is insufficient for astrocytoma formation
-
Bajenaru, M.L., Zhu, Y., Hedrick, N.M., Donahoe, J., Parada, L.F. and Gutmann, D.H. (2002) Astrocyte-specific inactivation of the neurofibromatosis 1 gene (Nf1) is insufficient for astrocytoma formation. Mol. Cell. Biol., 22, 5100-5113.
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 5100-5113
-
-
Bajenaru, M.L.1
Zhu, Y.2
Hedrick, N.M.3
Donahoe, J.4
Parada, L.F.5
Gutmann, D.H.6
-
12
-
-
0346059618
-
Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity
-
Bajenaru, M.L., Hernandez, M.R., Perry, A., Zhu, Y., Parada, L.F., Garbow, J.R. and Gutmann, D.H. (2003) Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity. Cancer Res., 63, 8573-8577.
-
(2003)
Cancer Res
, vol.63
, pp. 8573-8577
-
-
Bajenaru, M.L.1
Hernandez, M.R.2
Perry, A.3
Zhu, Y.4
Parada, L.F.5
Garbow, J.R.6
Gutmann, D.H.7
-
13
-
-
11144230288
-
Natural history of neurofibromatosis 1-associated optic nerve glioma in mice
-
Bajenaru, M.L., Garbow, J.R., Perry, A., Hernandez, M.R. and Gutmann, D.H. (2005) Natural history of neurofibromatosis 1-associated optic nerve glioma in mice. Ann. Neurol., 57, 119-127.
-
(2005)
Ann. Neurol
, vol.57
, pp. 119-127
-
-
Bajenaru, M.L.1
Garbow, J.R.2
Perry, A.3
Hernandez, M.R.4
Gutmann, D.H.5
-
14
-
-
31144472425
-
Inactivation of Nf1 in CNS causes increased glial progenitor proliferation and optic glioma formation
-
Zhu, Y., Harada, T., Liu, L., Lush, M.E., Guignard, F., Harada, C., Burns, D.K., Bajenaru, M.L., Gutmann, D.H. and Parada, L.F. (2005) Inactivation of Nf1 in CNS causes increased glial progenitor proliferation and optic glioma formation. Development., 132, 5577-5588.
-
(2005)
Development
, vol.132
, pp. 5577-5588
-
-
Zhu, Y.1
Harada, T.2
Liu, L.3
Lush, M.E.4
Guignard, F.5
Harada, C.6
Burns, D.K.7
Bajenaru, M.L.8
Gutmann, D.H.9
Parada, L.F.10
-
15
-
-
0029781336
-
Distribution and characterization of microglia/macrophages in human brain tumors
-
Roggendorf, W., Strupp, S. and Paulus, W. (1996) Distribution and characterization of microglia/macrophages in human brain tumors. Acta Neuropathol. (Berl.), 92, 288-293.
-
(1996)
Acta Neuropathol. (Berl.)
, vol.92
, pp. 288-293
-
-
Roggendorf, W.1
Strupp, S.2
Paulus, W.3
-
16
-
-
0034093158
-
Flow cytometric characterization of tumor-associated macrophages in experimental gliomas
-
Badie, B. and Schartner, J.M. (2000) Flow cytometric characterization of tumor-associated macrophages in experimental gliomas. Neurosurgery 46, 957-961.
-
(2000)
Neurosurgery
, vol.46
, pp. 957-961
-
-
Badie, B.1
Schartner, J.M.2
-
17
-
-
27244451954
-
Role of microglia in the central nervous system's immune response
-
Streit, W.J., Conde, J.R., Fendrick, S.E., Flanary, B.E. and Mariani, C.L. (2005) Role of microglia in the central nervous system's immune response. Neurol. Res., 27, 685-691.
-
(2005)
Neurol. Res
, vol.27
, pp. 685-691
-
-
Streit, W.J.1
Conde, J.R.2
Fendrick, S.E.3
Flanary, B.E.4
Mariani, C.L.5
-
18
-
-
0041835842
-
Monocyte chemoattractant protein-1 increases microglial infiltration and aggressiveness of gliomas
-
Platten, M., Kretz, A., Naumann, U., Aulwurm, S., Egashira, K., Isenmann, S. and Weller, M. (2003) Monocyte chemoattractant protein-1 increases microglial infiltration and aggressiveness of gliomas. Ann. Neurol., 54, 388-392.
-
(2003)
Ann. Neurol
, vol.54
, pp. 388-392
-
-
Platten, M.1
Kretz, A.2
Naumann, U.3
Aulwurm, S.4
Egashira, K.5
Isenmann, S.6
Weller, M.7
-
19
-
-
24644490056
-
Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2
-
Markovic, D.S., Glass, R., Synowitz, M., Rooijen, N. and Kettenmann, H. (2005) Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2. J. Neuropathol. Exp. Neurol., 64, 754-762.
-
(2005)
J. Neuropathol. Exp. Neurol
, vol.64
, pp. 754-762
-
-
Markovic, D.S.1
Glass, R.2
Synowitz, M.3
Rooijen, N.4
Kettenmann, H.5
-
20
-
-
0026646656
-
Biology of adult human microglia in culture: Comparisons with peripheral blood monocytes and astrocytes
-
Williams, K, Bar-Or, A., Ulvestad, E., Olivier, A., Antel, J.P. and Yong, V.W. (1992) Biology of adult human microglia in culture: comparisons with peripheral blood monocytes and astrocytes. J. Neuropathol. Exp. Neurol., 51, 538-549.
-
(1992)
J. Neuropathol. Exp. Neurol
, vol.51
, pp. 538-549
-
-
Williams, K.1
Bar-Or, A.2
Ulvestad, E.3
Olivier, A.4
Antel, J.P.5
Yong, V.W.6
-
21
-
-
0028558519
-
Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen-presenting cells
-
Ulvestad, E., Williams, K, Bjerkvig, R., Tiekotter, K, Antel, J. and Matre, R. (1994) Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen-presenting cells. J. Leukoc. Biol., 56, 732-740.
-
(1994)
J. Leukoc. Biol
, vol.56
, pp. 732-740
-
-
Ulvestad, E.1
Williams, K.2
Bjerkvig, R.3
Tiekotter, K.4
Antel, J.5
Matre, R.6
-
22
-
-
0028123075
-
Phenotypic differences between human monocytes/macrophages and microglial cells studied in situ and in vitro
-
Ulvestad, E., Williams, K., Mork, S., Antel, J. and Nyland, H. (1994) Phenotypic differences between human monocytes/macrophages and microglial cells studied in situ and in vitro. J. Neuropathol. Exp. Neurol., 53, 492-501.
-
(1994)
J. Neuropathol. Exp. Neurol
, vol.53
, pp. 492-501
-
-
Ulvestad, E.1
Williams, K.2
Mork, S.3
Antel, J.4
Nyland, H.5
-
23
-
-
0344013138
-
High-yield isolation of murine microglia by mild trypsinization
-
Saura, J., Tusell, J.M. and Serratosa, J. (2003) High-yield isolation of murine microglia by mild trypsinization. Glia, 44, 183-189.
-
(2003)
Glia
, vol.44
, pp. 183-189
-
-
Saura, J.1
Tusell, J.M.2
Serratosa, J.3
-
24
-
-
0141529951
-
The neurofibromatosis 1 gene product neurofibromin regulates pituitary adenylate cyclase-activating polypeptide-mediated signaling in astrocytes
-
Dasgupta, B., Dugan, L.L. and Gutmann, D.H. (2003) The neurofibromatosis 1 gene product neurofibromin regulates pituitary adenylate cyclase-activating polypeptide-mediated signaling in astrocytes. J. Neurosci., 23, 8949-8954.
-
(2003)
J. Neurosci
, vol.23
, pp. 8949-8954
-
-
Dasgupta, B.1
Dugan, L.L.2
Gutmann, D.H.3
-
25
-
-
16844375160
-
Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors
-
Dasgupta, B., Yi, Y., Chen, D.Y., Weber, J.D. and Gutmann, D.H. (2005) Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors. Cancer Res., 65, 2755-2760.
-
(2005)
Cancer Res
, vol.65
, pp. 2755-2760
-
-
Dasgupta, B.1
Yi, Y.2
Chen, D.Y.3
Weber, J.D.4
Gutmann, D.H.5
-
26
-
-
0030222037
-
Microglia: A Sensor for Pathological Events in the CNS
-
Kreutzberg, G.W. (1996) Microglia: A Sensor for Pathological Events in the CNS. Trends Neurosci., 19, 312-318.
-
(1996)
Trends Neurosci
, vol.19
, pp. 312-318
-
-
Kreutzberg, G.W.1
-
27
-
-
0027245888
-
Macrophages and inflammation in the central nervous system
-
Perry, V.H., Andersson, P.B. and Gordon, S. (1993) Macrophages and inflammation in the central nervous system. Trends Neurosci., 16, 268-273.
-
(1993)
Trends Neurosci
, vol.16
, pp. 268-273
-
-
Perry, V.H.1
Andersson, P.B.2
Gordon, S.3
-
28
-
-
0032931667
-
In vitro modulation of microglia motility by glioma cells is mediated by hepatocyte growth factor/scatter factor
-
Badie, B., Schartner, J., Klaver, J. and Vorpahl, J. (1999) In vitro modulation of microglia motility by glioma cells is mediated by hepatocyte growth factor/scatter factor. Neurosurgery, 44, 1077-1082.
-
(1999)
Neurosurgery
, vol.44
, pp. 1077-1082
-
-
Badie, B.1
Schartner, J.2
Klaver, J.3
Vorpahl, J.4
-
29
-
-
33644841301
-
Insulin-like growth factor I and Ii expression and modulation in amoeboid microglial cells by lipopolysaccharide and retinoic acid
-
Kaur, C., Sivakumar, V., Dheen, S.T. and Ling, E.A. (2006) Insulin-like growth factor I and Ii expression and modulation in amoeboid microglial cells by lipopolysaccharide and retinoic acid. Neuroscience, 138, 1233-1244.
-
(2006)
Neuroscience
, vol.138
, pp. 1233-1244
-
-
Kaur, C.1
Sivakumar, V.2
Dheen, S.T.3
Ling, E.A.4
-
30
-
-
27444434975
-
Disruption of the hyaluronan-based extracellular matrix in spinal cord promotes astrocyte proliferation
-
Struve, J., Maher, P.C., Li, Y.Q., Kinney, S., Fehlings, M.G., Kuntz, C. and Sherman, L.S. (2005) Disruption of the hyaluronan-based extracellular matrix in spinal cord promotes astrocyte proliferation. Glia, 52, 16-24.
-
(2005)
Glia
, vol.52
, pp. 16-24
-
-
Struve, J.1
Maher, P.C.2
Li, Y.Q.3
Kinney, S.4
Fehlings, M.G.5
Kuntz, C.6
Sherman, L.S.7
-
31
-
-
29444443660
-
Differential selectivity of hyaluronidase inhibitors toward acidic and basic hyaluronidases
-
Isoyama, T., Thwaites, D., Selzer, M.G., Carey, R.I., Barbucci, R. and Lokeshwar, V.B. (2006) Differential selectivity of hyaluronidase inhibitors toward acidic and basic hyaluronidases. Glycobiology, 16, 11-21.
-
(2006)
Glycobiology
, vol.16
, pp. 11-21
-
-
Isoyama, T.1
Thwaites, D.2
Selzer, M.G.3
Carey, R.I.4
Barbucci, R.5
Lokeshwar, V.B.6
-
32
-
-
0037443055
-
Dynamic regulation of the Ras pathway via proteolysis of the Nf1 tumor suppressor
-
Cichowski, K., Santiago, S., Jardim, M., Johnson, B.W. and Jacks, T. (2003) Dynamic regulation of the Ras pathway via proteolysis of the Nf1 tumor suppressor. Genes Dev., 17, 449-454.
-
(2003)
Genes Dev
, vol.17
, pp. 449-454
-
-
Cichowski, K.1
Santiago, S.2
Jardim, M.3
Johnson, B.W.4
Jacks, T.5
-
33
-
-
0033799930
-
Loss of neurofibromin is associated with activation of Ras/Mapk and Pi3-K/Akt signaling in a neurofibromatosis 1 astrocytoma
-
Lau, N., Feldkamp, M.M., Roncari, L, Loehr, A.H., Shannon, P., Gutmann, D.H. and Guha, A. (2000) Loss of neurofibromin is associated with activation of Ras/Mapk and Pi3-K/Akt signaling in a neurofibromatosis 1 astrocytoma. J. Neuropathol. Exp. Neurol., 59, 759-767.
-
(2000)
J. Neuropathol. Exp. Neurol
, vol.59
, pp. 759-767
-
-
Lau, N.1
Feldkamp, M.M.2
Roncari, L.3
Loehr, A.H.4
Shannon, P.5
Gutmann, D.H.6
Guha, A.7
-
34
-
-
0032101134
-
Nf1 regulates hematopoietic progenitor cell growth Ras signaling in response to multiple cytokines
-
Zhang, Y.Y., Vik, T.A., Ryder, J.W., Srour, E.F., Jacks, T., Shannon, K. and Clapp, D.W. (1998) Nf1 regulates hematopoietic progenitor cell growth Ras signaling in response to multiple cytokines. J. Exp. Med. 187, 1893-1902.
-
(1998)
J. Exp. Med
, vol.187
, pp. 1893-1902
-
-
Zhang, Y.Y.1
Vik, T.A.2
Ryder, J.W.3
Srour, E.F.4
Jacks, T.5
Shannon, K.6
Clapp, D.W.7
-
35
-
-
0036161092
-
Flow cytometric analysis of inflammatory cells in ischemic rat brain
-
Campanella, M., Sciorati, C., Tarozzo, G. and Beltramo, M. (2002) Flow cytometric analysis of inflammatory cells in ischemic rat brain. Stroke, 33, 586-592.
-
(2002)
Stroke
, vol.33
, pp. 586-592
-
-
Campanella, M.1
Sciorati, C.2
Tarozzo, G.3
Beltramo, M.4
-
36
-
-
0035865406
-
Brain dendritic cells and macrophages/microglia in central nervous system inflammation
-
Fischer, H.G. and Reichmann, G. (2001) Brain dendritic cells and macrophages/microglia in central nervous system inflammation. J. Immunol., 166, 2717-2726.
-
(2001)
J. Immunol
, vol.166
, pp. 2717-2726
-
-
Fischer, H.G.1
Reichmann, G.2
-
37
-
-
0035871840
-
Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
-
Tikka, T., Fiebich, B.L., Goldsteins, G., Keinanen, R. and Koistinaho, J. (2001) Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia. J. Neurosci., 21, 2580-2588.
-
(2001)
J. Neurosci
, vol.21
, pp. 2580-2588
-
-
Tikka, T.1
Fiebich, B.L.2
Goldsteins, G.3
Keinanen, R.4
Koistinaho, J.5
-
38
-
-
0036522967
-
Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of parkinson disease
-
Wu, D.C., Jackson-Lewis, V., Vila, M., Tieu, K, Teismann, P., Vadseth, C., Choi, D.K., Ischiropoulos, H. and Przedborski, S. (2002) Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of parkinson disease. J. Neurosci., 22, 1763-1771.
-
(2002)
J. Neurosci
, vol.22
, pp. 1763-1771
-
-
Wu, D.C.1
Jackson-Lewis, V.2
Vila, M.3
Tieu, K.4
Teismann, P.5
Vadseth, C.6
Choi, D.K.7
Ischiropoulos, H.8
Przedborski, S.9
-
39
-
-
0032442475
-
Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia
-
Yrjanheikki, J., Keinanen, R., Pellikka, M., Hokfelt, T. and Koistinaho, J. (1998) Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia. Proc. Natl Acad Sci. USA 95, 15769-15774.
-
(1998)
Proc. Natl Acad Sci. USA
, vol.95
, pp. 15769-15774
-
-
Yrjanheikki, J.1
Keinanen, R.2
Pellikka, M.3
Hokfelt, T.4
Koistinaho, J.5
-
40
-
-
33646439133
-
Activated microglia contribute to the maintenance of chronic pain after spinal cord injury
-
Hains, B.C. and Waxman, S.G. (2006) Activated microglia contribute to the maintenance of chronic pain after spinal cord injury. J. Neurosci., 26, 4308-4317.
-
(2006)
J. Neurosci
, vol.26
, pp. 4308-4317
-
-
Hains, B.C.1
Waxman, S.G.2
-
41
-
-
0032442475
-
Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia
-
Yrjanheikki, J., Keinanen, R., Pellikka, M., Hokfelt, T. and Koistinaho, J. (1998) Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia. Proc. Natl Acad. Sci. USA 95, 15769-15774.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 15769-15774
-
-
Yrjanheikki, J.1
Keinanen, R.2
Pellikka, M.3
Hokfelt, T.4
Koistinaho, J.5
-
42
-
-
0033539522
-
A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window
-
Yrjanheikki, J., Tikka, T., Keinanen, R., Goldsteins, G., Chan, P.H. and Koistinaho, J. (1999) A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window. Proc. Natl Acad. Sci. USA, 96, 13496-13500.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 13496-13500
-
-
Yrjanheikki, J.1
Tikka, T.2
Keinanen, R.3
Goldsteins, G.4
Chan, P.H.5
Koistinaho, J.6
-
43
-
-
0029146734
-
The tetracycline analogs minocycline and doxycycline inhibit angiogenesis in vitro by a non-metalloproteinase-dependent mechanism
-
Gilbertson-Beadling, S., Powers, E.A., Stamp-Cole, M., Scott, P.S., Wallace, T.L., Copeland, J., Petzold, G., Mitchell, M., Ledbetter, S. and Poorman, R. (1995) The tetracycline analogs minocycline and doxycycline inhibit angiogenesis in vitro by a non-metalloproteinase-dependent mechanism. Cancer Chemother. Pharmacol., 36, 418-424.
-
(1995)
Cancer Chemother. Pharmacol
, vol.36
, pp. 418-424
-
-
Gilbertson-Beadling, S.1
Powers, E.A.2
Stamp-Cole, M.3
Scott, P.S.4
Wallace, T.L.5
Copeland, J.6
Petzold, G.7
Mitchell, M.8
Ledbetter, S.9
Poorman, R.10
-
44
-
-
0025924722
-
Angiogenesis inhibition by minocycline
-
Tamargo, R.J., Bok, R.A. and Brem, H. (1991) Angiogenesis inhibition by minocycline. Cancer Res., 51, 672-675.
-
(1991)
Cancer Res
, vol.51
, pp. 672-675
-
-
Tamargo, R.J.1
Bok, R.A.2
Brem, H.3
-
45
-
-
0348149012
-
The tumor microenvironment: A critical determinant of neoplastic evolution
-
van Kempen, L.C., Ruiter, D.J., van Muijen, G.N. and Coussens, L.M. (2003) The tumor microenvironment: A critical determinant of neoplastic evolution. Eur. J. Cell. Biol., 82, 539-548.
-
(2003)
Eur. J. Cell. Biol
, vol.82
, pp. 539-548
-
-
van Kempen, L.C.1
Ruiter, D.J.2
van Muijen, G.N.3
Coussens, L.M.4
-
46
-
-
9244227134
-
Stromal fibroblasts in cancer initiation and progression
-
Bhowmick, N.A., Neilson, E.G. and Moses, H.L. (2004) Stromal fibroblasts in cancer initiation and progression. Nature, 432, 332-337.
-
(2004)
Nature
, vol.432
, pp. 332-337
-
-
Bhowmick, N.A.1
Neilson, E.G.2
Moses, H.L.3
-
47
-
-
3142512612
-
Molecular characterization of the tumor microenvironment in breast cancer
-
Allinen, M., Beroukhim, R., Cai, L., Brennan, C., Lahti-Domenici, J., Huang, H., Porter, D., Hu, M., Chin, L., Richardson, A. et al. (2004) Molecular characterization of the tumor microenvironment in breast cancer. Cancer Cell, 6, 17-32.
-
(2004)
Cancer Cell
, vol.6
, pp. 17-32
-
-
Allinen, M.1
Beroukhim, R.2
Cai, L.3
Brennan, C.4
Lahti-Domenici, J.5
Huang, H.6
Porter, D.7
Hu, M.8
Chin, L.9
Richardson, A.10
-
48
-
-
0344823964
-
A small-molecule antagonist of Cxcr4 inhibits intracranial growth of primary brain tumors
-
Rubin, J.B., Kung, A.L., Klein, R.S., Chan, J.A., Sun, Y., Schmidt, K., Kieran, M.W., Luster, A.D. and Segal, R.A. (2003) A small-molecule antagonist of Cxcr4 inhibits intracranial growth of primary brain tumors. Proc. Natl Acad. Sci. USA, 100, 13513-13518.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 13513-13518
-
-
Rubin, J.B.1
Kung, A.L.2
Klein, R.S.3
Chan, J.A.4
Sun, Y.5
Schmidt, K.6
Kieran, M.W.7
Luster, A.D.8
Segal, R.A.9
-
49
-
-
31544476294
-
Timp-3 deficiency in the host, but not in the tumor, enhances tumor growth and angiogenesis
-
Cruz-Munoz, W., Kim, I. and Khokha, R. (2006) Timp-3 deficiency in the host, but not in the tumor, enhances tumor growth and angiogenesis. Oncogene., 25, 650-655.
-
(2006)
Oncogene
, vol.25
, pp. 650-655
-
-
Cruz-Munoz, W.1
Kim, I.2
Khokha, R.3
-
50
-
-
0345601083
-
Met, metastasis, motility and more
-
Birchmeier, C., Birchmeier, W., Gherardi, E. and Vande Woude, G.F. (2003) Met, metastasis, motility and more. Nat. Rev. Mol. Cell Biol. 4, 915-925.
-
(2003)
Nat. Rev. Mol. Cell Biol
, vol.4
, pp. 915-925
-
-
Birchmeier, C.1
Birchmeier, W.2
Gherardi, E.3
Vande Woude, G.F.4
-
51
-
-
0033381357
-
The role for transforming growth factor-beta (Tgf-beta) in human cancer
-
Gold, L.I. (1999) The role for transforming growth factor-beta (Tgf-beta) in human cancer. Crit. Rev. Oncog., 10, 303-360.
-
(1999)
Crit. Rev. Oncog
, vol.10
, pp. 303-360
-
-
Gold, L.I.1
-
52
-
-
0021720359
-
Growth inhibitor from Bsc-1 cells closely related to platelet type beta transforming growth factor
-
Tucker, R.F., Shipley, G.D., Moses, H.L. and Holley, R.W. (1984) Growth inhibitor from Bsc-1 cells closely related to platelet type beta transforming growth factor. Science, 226, 705-707.
-
(1984)
Science
, vol.226
, pp. 705-707
-
-
Tucker, R.F.1
Shipley, G.D.2
Moses, H.L.3
Holley, R.W.4
-
53
-
-
28944432805
-
Selective evolution of stromal mesenchyme with P53 loss in response to epithelial tumorigenesis
-
Hill, R., Song, Y., Cardiff, R.D. and Van Dyke, T. (2005) Selective evolution of stromal mesenchyme with P53 loss in response to epithelial tumorigenesis. Cell, 123, 1001-1011.
-
(2005)
Cell
, vol.123
, pp. 1001-1011
-
-
Hill, R.1
Song, Y.2
Cardiff, R.D.3
Van Dyke, T.4
-
54
-
-
0033214846
-
In vitro and in vivo effects of a farnesyltransferase inhibitor on Nf1-deficient hematopoietic cells
-
Mahgoub, N., Taylor, B.R., Gratiot, M., Kohl, N.E., Gibbs, J.B., Jacks, T. and Shannon, K.M. (1999) In vitro and in vivo effects of a farnesyltransferase inhibitor on Nf1-deficient hematopoietic cells. Blood., 94, 2469-2476.
-
(1999)
Blood
, vol.94
, pp. 2469-2476
-
-
Mahgoub, N.1
Taylor, B.R.2
Gratiot, M.3
Kohl, N.E.4
Gibbs, J.B.5
Jacks, T.6
Shannon, K.M.7
-
55
-
-
1642489095
-
Tie2-Cre-induced inactivation of a conditional mutant Nf1 allele in mouse results in a myeloproliferative disorder that models juvenile myelomonocytic leukemia
-
Gitler, A.D., Kong, Y., Choi, J.K., Zhu, Y., Pear, W.S. and Epstein, J.A. (2004) Tie2-Cre-induced inactivation of a conditional mutant Nf1 allele in mouse results in a myeloproliferative disorder that models juvenile myelomonocytic leukemia. Pediatr. Res., 55, 581-584.
-
(2004)
Pediatr. Res
, vol.55
, pp. 581-584
-
-
Gitler, A.D.1
Kong, Y.2
Choi, J.K.3
Zhu, Y.4
Pear, W.S.5
Epstein, J.A.6
-
56
-
-
0037012848
-
Neurofibromas in Nf1: Schwann cell origin and role of tumor environment
-
Zhu, Y., Ghosh, P., Charnay, P., Burns, D.K. and Parada, L.F. (2002) Neurofibromas in Nf1: Schwann cell origin and role of tumor environment. Science, 296, 920-922.
-
(2002)
Science
, vol.296
, pp. 920-922
-
-
Zhu, Y.1
Ghosh, P.2
Charnay, P.3
Burns, D.K.4
Parada, L.F.5
-
57
-
-
0035109208
-
Increased microglia proliferation separates pilocytic astrocytomas from diffuse astrocytomas: A double labeling study
-
Klein, R. and Roggendorf, W. (2001) Increased microglia proliferation separates pilocytic astrocytomas from diffuse astrocytomas: A double labeling study. Acta. Neuropathol. (Berl.), 101, 245-248.
-
(2001)
Acta. Neuropathol. (Berl.)
, vol.101
, pp. 245-248
-
-
Klein, R.1
Roggendorf, W.2
-
58
-
-
0033864837
-
Loss of neurofibromatosis 1 (Nf1) gene expression in Nf1-associated pilocytic astrocytomas
-
Gutmann, D.H., Donahoe, J., Brown, T., James, C.D. and Perry, A. (2000) Loss of neurofibromatosis 1 (Nf1) gene expression in Nf1-associated pilocytic astrocytomas. Neuropathol. Appl. Neurobiol., 26, 361-367.
-
(2000)
Neuropathol. Appl. Neurobiol
, vol.26
, pp. 361-367
-
-
Gutmann, D.H.1
Donahoe, J.2
Brown, T.3
James, C.D.4
Perry, A.5
-
59
-
-
0026755385
-
Recombinant human stem cell factor stimulates growth of a human glioblastoma cell line expressing c-kit Protooncogene
-
Berdel, W.E., de Vos, S., Maurer, J., Oberberg, D., von Marschall, Z., Schroeder, J.K., Li, J., Ludwig, W.D., Kreuser, E.D., Thiel, E. et al. (1992) Recombinant human stem cell factor stimulates growth of a human glioblastoma cell line expressing c-kit Protooncogene. Cancer Res., 52, 3498-3502.
-
(1992)
Cancer Res
, vol.52
, pp. 3498-3502
-
-
Berdel, W.E.1
de Vos, S.2
Maurer, J.3
Oberberg, D.4
von Marschall, Z.5
Schroeder, J.K.6
Li, J.7
Ludwig, W.D.8
Kreuser, E.D.9
Thiel, E.10
-
60
-
-
20444436815
-
Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop
-
Goswami, S., Sahai, E., Wyckoff, J.B., Cammer, M., Cox, D., Pixley, F.J., Stanley, E.R., Segall, J.E. and Condeelis, J.S. (2005) Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop. Cancer Res., 65, 5278-5283.
-
(2005)
Cancer Res
, vol.65
, pp. 5278-5283
-
-
Goswami, S.1
Sahai, E.2
Wyckoff, J.B.3
Cammer, M.4
Cox, D.5
Pixley, F.J.6
Stanley, E.R.7
Segall, J.E.8
Condeelis, J.S.9
-
61
-
-
0027246256
-
Secretion of epidermal growth factor by macrophages associated with breast carcinoma
-
O'Sullivan, C., Lewis, C.E., Harris, A.L. and McGee, J.O. (1993) Secretion of epidermal growth factor by macrophages associated with breast carcinoma. Lancet, 342, 148-149.
-
(1993)
Lancet
, vol.342
, pp. 148-149
-
-
O'Sullivan, C.1
Lewis, C.E.2
Harris, A.L.3
McGee, J.O.4
-
62
-
-
24044461733
-
Macrophage responses to hypoxia: Implications for tumor progression and anti-cancer therapies
-
Lewis, C. and Murdoch, C. (2005) Macrophage responses to hypoxia: implications for tumor progression and anti-cancer therapies. Am. J. Pathol., 167, 627-635.
-
(2005)
Am. J. Pathol
, vol.167
, pp. 627-635
-
-
Lewis, C.1
Murdoch, C.2
-
63
-
-
2442657786
-
Il-6 is required for glioma development in a mouse model
-
Weissenberger, J., Loeffler, S., Kappeler, A., Kopf, M., Lukes, A., Afanasieva, T.A., Aguzzi, A. and Weis, J. (2004) Il-6 is required for glioma development in a mouse model. Oncogene, 23, 3308-3316.
-
(2004)
Oncogene
, vol.23
, pp. 3308-3316
-
-
Weissenberger, J.1
Loeffler, S.2
Kappeler, A.3
Kopf, M.4
Lukes, A.5
Afanasieva, T.A.6
Aguzzi, A.7
Weis, J.8
-
64
-
-
0036626690
-
Overexpression of hyaluronan synthase-2 reduces the tumorigenic potential of glioma cells lacking hyaluronidase activity
-
Enegd, B., King, J.A., Stylli, S., Paradiso, L., Kaye, A.H. and Novak, U. (2002) Overexpression of hyaluronan synthase-2 reduces the tumorigenic potential of glioma cells lacking hyaluronidase activity. Neurosurgery, 50, 1311-1318.
-
(2002)
Neurosurgery
, vol.50
, pp. 1311-1318
-
-
Enegd, B.1
King, J.A.2
Stylli, S.3
Paradiso, L.4
Kaye, A.H.5
Novak, U.6
-
65
-
-
0036946575
-
Microglia promote glioma migration
-
Bettinger, L, Thanos, S. and Paulus, W. (2002) Microglia promote glioma migration. Acta. Neuropathol. (Berl.), 103, 351-355.
-
(2002)
Acta. Neuropathol. (Berl.)
, vol.103
, pp. 351-355
-
-
Bettinger, L.1
Thanos, S.2
Paulus, W.3
-
66
-
-
29244445813
-
Widespread Cxcr4 activation in astrocycomas revealed by phospho-Cxcr4-specific antibodies
-
Woerner, B.M., Warrington, N.M., Kung, A.L., Perry, A. and Rubin, J.B. (2005) Widespread Cxcr4 activation in astrocycomas revealed by phospho-Cxcr4-specific antibodies. Cancer Res., 65, 11392-11399.
-
(2005)
Cancer Res
, vol.65
, pp. 11392-11399
-
-
Woerner, B.M.1
Warrington, N.M.2
Kung, A.L.3
Perry, A.4
Rubin, J.B.5
-
67
-
-
33744722469
-
Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells
-
Munchhof, A.M., Li, F., White, H.A., Mead, L.E., Krier, T.R., Fenoglio, A., Li, X., Yuan, J., Yang, F.C. and Ingram, D.A. (2006) Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells. Hum. Mol. Genet., 15, 1858-1869.
-
(2006)
Hum. Mol. Genet
, vol.15
, pp. 1858-1869
-
-
Munchhof, A.M.1
Li, F.2
White, H.A.3
Mead, L.E.4
Krier, T.R.5
Fenoglio, A.6
Li, X.7
Yuan, J.8
Yang, F.C.9
Ingram, D.A.10
-
68
-
-
11244344906
-
Glioma formation in neurofibromatosis 1 reflects preferential activation of K-Ras in astrocytes
-
Dasgupta, B., Li, W., Perry, A. and Gutmann, D.H. (2005) Glioma formation in neurofibromatosis 1 reflects preferential activation of K-Ras in astrocytes. Cancer Res., 65, 236-245.
-
(2005)
Cancer Res
, vol.65
, pp. 236-245
-
-
Dasgupta, B.1
Li, W.2
Perry, A.3
Gutmann, D.H.4
-
69
-
-
0033199189
-
Identification of bladder tumor-derived hyaluronidase: Its similarity to Hyall
-
Lokeshwar, V.B., Young, M.J., Goudarzi, G., Iida, N., Yudin, A.I., Cherr, G.N. and Selzer, M.G. (1999) Identification of bladder tumor-derived hyaluronidase: Its similarity to Hyall. Cancer Res., 59, 4464-4470.
-
(1999)
Cancer Res
, vol.59
, pp. 4464-4470
-
-
Lokeshwar, V.B.1
Young, M.J.2
Goudarzi, G.3
Iida, N.4
Yudin, A.I.5
Cherr, G.N.6
Selzer, M.G.7
-
70
-
-
0031059785
-
Tumor-derived hyaluronidase: A diagnostic urine market for high-grade bladder cancer
-
Pham, H.T., Block N.L. and Lokeshwar, V.B. (1997) Tumor-derived hyaluronidase: A diagnostic urine market for high-grade bladder cancer. Cancer Res., 57, 778-783.
-
(1997)
Cancer Res
, vol.57
, pp. 778-783
-
-
Pham, H.T.1
Block, N.L.2
Lokeshwar, V.B.3
-
71
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
-
Livak, K.J. and Schmittgen, T.D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods, 25, 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
|