-
6
-
-
0025369709
-
Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus
-
(1990)
Cell
, vol.62
, pp. 187-192
-
-
Viskochil, D.1
Buchberg, A.M.2
Xu, G.3
Cawthon, R.M.4
Stevens, J.5
Wolff, R.K.6
Culver, M.7
Carey, J.C.8
Copeland, N.G.9
Jenkins, N.A.10
-
7
-
-
0025326726
-
A major segment of the neurofibromatosis type 1 gene: CDNA sequence, genomic structure and point mutations
-
(1990)
Cell
, vol.62
, pp. 193-201
-
-
Cawthon, R.M.1
Weiss, M.2
Xu, G.3
Viskochil, D.4
Culver, M.5
Stevens, J.6
Robertson, M.7
Dunn, D.8
Gesteland, R.9
O'Connell, P.10
White, R.11
-
8
-
-
0025297599
-
Type 1 neurofibromatosis gene: Identification of a large transcript disrupted in three NF1 patients
-
(1990)
Science
, vol.249
, pp. 181-186
-
-
Wallace, M.R.1
Marchuk, D.A.2
Andersen, L.B.3
Letcher, R.4
Odeh, H.M.5
Saulino, A.M.6
Fountain, J.W.7
Brereton, A.8
Nicholson, J.9
Mitchell, A.L.10
-
9
-
-
0025244911
-
The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S.cerevisiae
-
(1990)
Cell
, vol.63
, pp. 835-841
-
-
Xu, G.1
Lin, B.2
Tanaka, K.3
Dunn, D.4
Wood, D.5
Gesteland, R.6
White, R.7
Weiss, R.8
Tamanoi, F.9
-
10
-
-
0025091465
-
The neurofibromatosis type 1 gene encodes a protein related to GAP
-
(1990)
Cell
, vol.62
, pp. 599-608
-
-
Xu, G.1
O'Connell, P.2
Viskochil, D.3
Cawthon, R.4
Robertson, R.5
Culver, M.6
Dunn, D.7
Stevens, J.8
Gesteland, R.9
White, R.10
Weiss, R.11
-
12
-
-
0025251137
-
The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21
-
(1990)
Cell
, vol.63
, pp. 843-849
-
-
Martin, G.A.1
Viskochil, D.2
Bollag, G.3
McCabe, P.C.4
Crosier, W.J.5
Haubruck, H.6
Conroy, L.7
Clark, R.8
O'Connell, P.9
Cawthon, R.M.10
-
14
-
-
9044251606
-
Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells
-
(1996)
Nature Genet.
, vol.12
, pp. 144-148
-
-
Bollag, G.1
Clapp, D.W.2
Shih, S.3
Adler, F.4
Zhang, Y.Y.5
Thompson, P.6
Lange, B.J.7
Freedman, M.H.8
McCormick, F.9
Jacks, T.10
Shannon, K.11
-
21
-
-
0028349997
-
Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues
-
(1994)
Genes Dev.
, vol.8
, pp. 1019-1029
-
-
Brannan, C.I.1
Perkins, A.S.2
Vogel, K.S.3
Ratner, N.4
Nordlund, M.L.5
Reid, S.W.6
Buchberg, A.M.7
Jenkins, N.A.8
Parada, L.F.9
Copeland, N.G.10
-
22
-
-
0032763861
-
Mouse models of tumor development in neurofibromatosis type 1
-
(1999)
Science
, vol.286
, pp. 2172-2176
-
-
Cichowski, K.1
Shih, T.S.2
Schmitt, E.3
Santiago, S.4
Reilly, K.5
McLaughlin, M.E.6
Bronson, R.T.7
Jacks, T.8
-
23
-
-
0025108408
-
Chromosome 17p deletions and p53 gene mutation associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 5435-5439
-
-
Menon, A.G.1
Anderson, K.M.2
Riccardi, M.3
Chung, R.Y.4
Whaley, J.M.5
Yandell, D.W.6
Farmer, G.E.7
Freidman, R.M.8
Lee, J.K.9
Li, F.P.10
-
31
-
-
0034598363
-
Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo
-
(2000)
J. Exp. Med.
, vol.191
, pp. 181-187
-
-
Ingram, D.A.1
Yang, F.C.2
Travers, J.B.3
Wenning, M.J.4
Hiatt, K.5
New, S.6
Hood, A.7
Shannon, K.8
Williams, D.A.9
Clapp, D.W.10
-
33
-
-
0030996903
-
Rescue of a Drosophila NF1 mutant phenotype by protein kinase A
-
(1997)
Science
, vol.276
, pp. 791-794
-
-
The, I.1
Hannigan, G.E.2
Cowley, G.S.3
Reginald, S.4
Zhong, Y.5
Gusella, J.F.6
Hariharan, I.K.7
Bernards, A.8
-
34
-
-
0031038519
-
NF1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: Reversion of some phenotypes by an inhibitor of farsenyl protein transferase
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 862-872
-
-
Kim, H.A.1
Ling, B.2
Ratner, N.3
-
40
-
-
0027405720
-
A noel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor
-
(1993)
Cell
, vol.72
, pp. 1-20
-
-
Trofatter, J.A.1
MacCollin, M.M.2
Rutter, J.L.3
Murrell, J.R.4
Duyao, M.P.5
Parry, D.M.6
Eldridge, R.7
Kley, N.8
Menon, A.G.9
Pulaski, K.10
-
41
-
-
0027245423
-
Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2
-
(1993)
Nature
, vol.63
, pp. 515-521
-
-
Rouleau, G.A.1
Merel, P.2
Lutchman, M.3
Sanson, M.4
Zucman, J.5
Marineau, C.6
Hoang-Xuan, K.7
Demczuk, M.8
Desmaze, C.9
Plougastel, B.10
-
45
-
-
0033561026
-
Schwann cell hyperplasia and tumors in transgenic mice expressing a naturally occurring mutant NF2 protein
-
(1999)
Genes Dev.
, vol.13
, pp. 978-986
-
-
Giovannini, M.1
Robanus-Maandag, E.2
Niwa-Kawakita, M.3
van der Valk, M.4
Woodruff, J.M.5
Goutebroze, L.6
Merel, P.7
Berns, A.8
Thomas, G.9
-
48
-
-
0030759923
-
Neurofibromatosis 2 tumor suppressor protein co-localizes with ezrin and CD44 and associates with actin-containing cytoskeleton
-
(1997)
J. Cell Sci.
, vol.110
, pp. 2249-2260
-
-
Sainio, M.1
Zhao, F.2
Heiska, L.3
Turunen, O.4
den Bakker, M.5
Zwarthoff, E.6
Lutchman, M.7
Rouleau, G.A.8
Jaaskelainen, J.9
Vaheri, A.10
Carpen, O.11
-
50
-
-
0035871299
-
The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44
-
in press
-
(2001)
Genes Dev.
-
-
Morrison, H.1
Sherman, L.S.2
Legg, J.3
Banine, F.4
Isacke, C.5
Haipek, C.A.6
Gutmann, D.H.7
Ponta, H.8
Herrlich, P.9
-
55
-
-
0031890998
-
NHE-RF, a regulatory cofactor for Na+-H+ exchange, is a common interactor for merlin and ERM (MERM) proteins
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1273-1276
-
-
Murthy, A.1
Gonzalez-Agosti, C.2
Cordero, E.3
Pinney, D.4
Candia, C.5
Solomon, F.6
Gusella, J.7
Ramesh, V.8
-
60
-
-
0032578798
-
Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human schwannoma cells
-
(1998)
Oncogene
, vol.17
, pp. 2195-2209
-
-
Pelton, P.D.1
Sherman, L.S.2
Rizvi, T.A.3
Marchionni, M.A.4
Wood, P.5
Friedman, R.A.6
Ratner, N.7
-
61
-
-
0032899713
-
Increased expression of the NF2 tumor suppressor gene product, merlin, impairs cell motility, adhesion and spreading
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 267-275
-
-
Gutmann, D.H.1
Sherman, L.2
Seftor, L.3
Haipek, C.4
Lu, K.H.5
Hendrix, M.6
-
63
-
-
0033973369
-
The CD44 receptor of lymphoma cells: Structure-function relationships and mechanism of activation
-
(2000)
Cell Adhes. Commun.
, vol.7
, pp. 331-347
-
-
Rochman, M.1
Moll, J.2
Herrlich, P.3
Wallach, S.B.4
Nedetzki, S.5
Siono, R.6
Golan, I.7
Ish-Shalom, D.8
Naor, D.9
-
66
-
-
0030775695
-
Interdomain binding mediates tumor growth suppression by the NF2 gene product
-
(1997)
Oncogene
, vol.15
, pp. 2505-2509
-
-
Sherman, L.1
Xu, H.M.2
Geist, R.T.3
Saporito-Irwin, S.4
Howells, N.5
Ponta, H.6
Herrlich, P.7
Gutmann, D.H.8
-
69
-
-
0028849793
-
Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6213-6221
-
-
Komada, M.1
Mitamura, N.2
-
71
-
-
0033151614
-
Hrs, a FYE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis
-
(1999)
Genes Dev.
, vol.13
, pp. 1475-1485
-
-
Komada, M.1
Soriano, P.2
-
72
-
-
14444284098
-
Hrs is associated with STAM, a signal-transducing adaptor molecule
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32785-32791
-
-
Asao, H.1
Sasaki, Y.2
Arita, T.3
Tanaka, N.4
Endo, K.5
Kasai, H.6
Takeshita, T.7
Endo, Y.8
Fujita, T.9
Sugamura, K.10
-
73
-
-
0034462833
-
Hgs (Hrs), a FYVE domain protein, is involved in smad signaling through cooperation with SARA
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 9346-9355
-
-
Miura, S.1
Takeshita, T.2
Asao, H.3
Kimura, Y.4
Murata, K.5
Sasaki, Y.6
Hanai, J.I.7
Beppu, H.8
Tsukazaki, T.9
Wrana, J.L.10
-
77
-
-
0028264119
-
Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas
-
(1994)
Nature Genet.
, vol.6
, pp. 180-184
-
-
Ruttledge, M.H.1
Sarrazin, J.2
Rangaratnam, S.3
Phelan, C.M.4
Twist, E.5
Merel, P.6
Delattre, O.7
Thomas, G.8
Nordenskjold, M.9
Collins, P.10
-
78
-
-
15144359418
-
Universal absence of merlin, but not other ERM family members, in schwannomas
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1649-1654
-
-
Stemmer-Rachamimov, A.O.1
Xu, L.2
Gonzalez-Agosti, C.3
Burwick, J.A.4
Pinney, D.5
Beauchamp, R.6
Jacoby, L.B.7
Gusella, J.F.8
Ramesh, V.9
Louis, D.N.10
-
80
-
-
0029004033
-
Predominant occurrence of somatic mutations of the NF2 gene in meningiomas and schwannomas
-
(1995)
Genes Chromosomes Cancer
, vol.13
, pp. 211-216
-
-
Merel, P.1
Hoang-Xuan, K.2
Sanson, M.3
Moreau-Aubry, A.4
Bijisma, E.K.5
Lazaro, C.6
Moisan, J.P.7
Resche, F.8
Nishisho, I.9
Estivill, X.10
-
81
-
-
0028091283
-
The neurofibromatosis type 2 gene is inactivated in schwannomas
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 147-151
-
-
Twist, E.C.1
Ruttledge, M.H.2
Rouseau, M.3
Sanson, M.4
Papi, L.5
Merel, P.6
Delattre, O.7
Thomas, G.8
Rouleau, G.A.9
-
82
-
-
0031745533
-
Loss of the NF2 gene and merlin occur by the tumorlet stage of schwannoma development in neurofibromatosis 2
-
(1998)
J. Neuropathol. Exp. Neurol.
, vol.57
, pp. 1164-1167
-
-
Stemmer-Rachamimov, A.O.1
Ino, Y.2
Lim, Z.Y.3
Jacoby, L.B.4
MacCollin, M.5
Gusella, J.F.6
Ramesh, V.7
Louis, D.N.8
-
83
-
-
0033786149
-
Merlin, DAL-1 and progesterone receptor expression in clinicopathologic subsets of meningioma: A correlative immunohistochemistry study of 175 cases
-
(2000)
J. Neuropathol. Exp. Neurol.
, vol.59
, pp. 872-879
-
-
Perry, A.1
Cai, D.X.2
Scheithauer, B.W.3
Swanson, P.E.4
Lohse, C.M.5
Newsham, I.F.6
Weaver, A.7
Gutmann, D.H.8
-
85
-
-
0034640901
-
Loss of DAL-1, a protein 4.1-related tumor suppressor, is an important early event in the pathogenesis of meningiomas
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 1495-1500
-
-
Guttmann, D.H.1
Donahoe, J.2
Perry, A.3
Lemke, N.4
Gorse, K.5
Kittiniyom, K.6
Rempel, S.A.7
Gutierrez, J.A.8
Newsham, I.F.9
|