메뉴 건너뛰기




Volumn 403, Issue 6772, 2000, Pages 895-898

A neurofibromatosis-1-regulated pathway is required for learning in Drosophila

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; NEUROFIBROMIN; RAS PROTEIN;

EID: 0034708076     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35002593     Document Type: Article
Times cited : (219)

References (29)
  • 1
    • 0025201012 scopus 로고
    • The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins
    • Ballester, R. et al. The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins. Cell 63, 851-859 (1990).
    • (1990) Cell , vol.63 , pp. 851-859
    • Ballester, R.1
  • 2
    • 0029126877 scopus 로고
    • Neurofibromatosis type 1 and Ras-mediated signaling: Filling in the GAPs
    • Bernards, A. Neurofibromatosis type 1 and Ras-mediated signaling: filling in the GAPs. Biochim. Biophys. Acta 1242, 43-59 (1995).
    • (1995) Biochim. Biophys. Acta , vol.1242 , pp. 43-59
    • Bernards, A.1
  • 3
    • 0024205878 scopus 로고
    • Von Recklinghausen neurofibromatosis. A clinical and population study in south-east Wales
    • Huson, S. M., Harper, P. S. & Compston, D. A. Von Recklinghausen neurofibromatosis. A clinical and population study in south-east Wales. Brain 111, 1355-1381 (1988).
    • (1988) Brain , vol.111 , pp. 1355-1381
    • Huson, S.M.1    Harper, P.S.2    Compston, D.A.3
  • 5
    • 0025244911 scopus 로고
    • The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae
    • Xu, G. F. et al. The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae. Cell 63, 835-841 (1990).
    • (1990) Cell , vol.63 , pp. 835-841
    • Xu, G.F.1
  • 7
    • 0028307836 scopus 로고
    • Tumour predisposition in mice heterozygous for a targeted mutation in NF1
    • Jacks, T. et al. Tumour predisposition in mice heterozygous for a targeted mutation in NF1. Nature Genet. 7, 353-361 (1994)
    • (1994) Nature Genet. , vol.7 , pp. 353-361
    • Jacks, T.1
  • 8
    • 0029882903 scopus 로고    scopus 로고
    • Intellectual impairment in neurofibromatosis I
    • Ferner, R. E., Hughes, R. A. & Weinman, J. Intellectual impairment in neurofibromatosis I. J. Neurol. Sci. 138, 125-133 (1996).
    • (1996) J. Neurol. Sci. , vol.138 , pp. 125-133
    • Ferner, R.E.1    Hughes, R.A.2    Weinman, J.3
  • 9
    • 0029035129 scopus 로고
    • Cognitive function and academic performance in children with neurofibromatosis type I
    • North, K., Joy, P., Yuille, D., Cocks, N. & Hutchins, P. Cognitive function and academic performance in children with neurofibromatosis type I. Dev. Med. Child Neurol. 37, 427-436 (1995).
    • (1995) Dev. Med. Child Neurol. , vol.37 , pp. 427-436
    • North, K.1    Joy, P.2    Yuille, D.3    Cocks, N.4    Hutchins, P.5
  • 10
    • 0028307561 scopus 로고
    • Specific learning disability in children with neurofibromatosis type 1: Significance of MRI abnormalities
    • North, K. et al. Specific learning disability in children with neurofibromatosis type 1: significance of MRI abnormalities. Neurology 44, 878-883 (1994).
    • (1994) Neurology , vol.44 , pp. 878-883
    • North, K.1
  • 11
    • 0031018226 scopus 로고    scopus 로고
    • A mouse model for the learning and memory deficits associated with neurofibromatosis type 1
    • Silva, A. J. et al. A mouse model for the learning and memory deficits associated with neurofibromatosis type 1. Nature Genet. 15, 281-284 (1997).
    • (1997) Nature Genet. , vol.15 , pp. 281-284
    • Silva, A.J.1
  • 12
    • 0030996903 scopus 로고    scopus 로고
    • Rescue of a Drosophila NF1 mutant phenotype by protein kinase A
    • The, I. et al. Rescue of a Drosophila NF1 mutant phenotype by protein kinase A. Science 276, 791-794 (1997).
    • (1997) Science , vol.276 , pp. 791-794
    • The, I.1
  • 13
    • 0031007708 scopus 로고    scopus 로고
    • Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptide
    • Guo, H. F., The, I., Hannan, F., Bernards, A. & Zhong, Y. Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptide. Science 276, 795-798 (1997).
    • (1997) Science , vol.276 , pp. 795-798
    • Guo, H.F.1    The, I.2    Hannan, F.3    Bernards, A.4    Zhong, Y.5
  • 14
    • 0021174051 scopus 로고
    • Loss of calcium/calmudulin responsiveness in adenylate cyclase of rutagaba, a Drosophila learning mutant
    • Livingstone, M. S., Sziber, P. P. & Quinn, W. G. Loss of calcium/calmudulin responsiveness in adenylate cyclase of rutagaba, a Drosophila learning mutant. Cell 37, 205-215 (1984).
    • (1984) Cell , vol.37 , pp. 205-215
    • Livingstone, M.S.1    Sziber, P.P.2    Quinn, W.G.3
  • 15
    • 0026702557 scopus 로고
    • Preferential expression of the Drosophila rutabaga gene in mushroom bodies, neural centers for learning in insects
    • Han, P.-L., Levin, L. R., Reed, R. R. & Davis, R. L. Preferential expression of the Drosophila rutabaga gene in mushroom bodies, neural centers for learning in insects. Neuron 9, 619-627 (1992).
    • (1992) Neuron , vol.9 , pp. 619-627
    • Han, P.-L.1    Levin, L.R.2    Reed, R.R.3    Davis, R.L.4
  • 16
    • 0022119763 scopus 로고
    • Classical conditioning and retention in normal and mutant Drosophila melanogaster
    • Tully, T. & Quinn, W. G. Classical conditioning and retention in normal and mutant Drosophila melanogaster. J. Comp. Physiol. A Sens. Neural. Behav. Physiol. 157, 263-277 (1985).
    • (1985) J. Comp. Physiol. A Sens. Neural. Behav. Physiol. , vol.157 , pp. 263-277
    • Tully, T.1    Quinn, W.G.2
  • 17
    • 0028297332 scopus 로고
    • Associative odor learning in Drosophila abolished by chemical ablation of mushroom bodies
    • de Belle, J. S. & Heisenberg, M. Associative odor learning in Drosophila abolished by chemical ablation of mushroom bodies. Science 263, 692-695 (1994).
    • (1994) Science , vol.263 , pp. 692-695
    • De Belle, J.S.1    Heisenberg, M.2
  • 18
    • 0030449882 scopus 로고    scopus 로고
    • Associative learning disrupted by impaired Gs signaling in Drosophila mushroom bodies
    • Connolly, J. B. et al. Associative learning disrupted by impaired Gs signaling in Drosophila mushroom bodies. Science 274, 2104-2106 (1996).
    • (1996) Science , vol.274 , pp. 2104-2106
    • Connolly, J.B.1
  • 19
    • 0032576714 scopus 로고    scopus 로고
    • Integrin-mediated short-term memory in Drosophila
    • Grotewiel, M. S., Beck, C. D., Wu, K. H., Zhu, X. R. & Davis, R. L. Integrin-mediated short-term memory in Drosophila. Nature 391, 455-460 (1998).
    • (1998) Nature , vol.391 , pp. 455-460
    • Grotewiel, M.S.1    Beck, C.D.2    Wu, K.H.3    Zhu, X.R.4    Davis, R.L.5
  • 20
    • 0027640187 scopus 로고
    • Identification of linotte, a new gene affecting learning and memory in Drosophila melanogasler
    • Dura, I.-M., Preat, T. & Tully, T. Identification of linotte, a new gene affecting learning and memory in Drosophila melanogasler. J. Neurogenetics 9, 1-14 (1993).
    • (1993) J. Neurogenetics , vol.9 , pp. 1-14
    • Dura, I.-M.1    Preat, T.2    Tully, T.3
  • 21
    • 0027983479 scopus 로고
    • Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila
    • Yin, J. C. P. et al. Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila. Cell 79, 49-58 (1994).
    • (1994) Cell , vol.79 , pp. 49-58
    • Yin, J.C.P.1
  • 22
    • 0026567423 scopus 로고
    • 2+/calmodulin-responsive adenylyl cyclase
    • 2+/calmodulin-responsive adenylyl cyclase. Cell 68, 479-489 (1992).
    • (1992) Cell , vol.68 , pp. 479-489
    • Levin, L.R.1
  • 23
    • 0019350704 scopus 로고
    • Defect in cyclic-AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster
    • Byers, D., Davis, R. L. & Kiger, J. A. Defect in cyclic-AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster. Nature 289, 79-81 (1981).
    • (1981) Nature , vol.289 , pp. 79-81
    • Byers, D.1    Davis, R.L.2    Kiger, J.A.3
  • 25
    • 0028918468 scopus 로고
    • Protein kinase A and hedgehog signaling in Drosophila limb development
    • Jiang, J. & Struhl, G. Protein kinase A and hedgehog signaling in Drosophila limb development. Cell 80, 563-572 (1995).
    • (1995) Cell , vol.80 , pp. 563-572
    • Jiang, J.1    Struhl, G.2
  • 26
    • 0025882880 scopus 로고
    • Interactions between adenylyl cyclase and the yeast GTPase-activating protein IRAI
    • Mitts, M. R., Bradshaw-Rouse, J. & Heideman, W. Interactions between adenylyl cyclase and the yeast GTPase-activating protein IRAI. Mol. Cell. Biol. 11, 4591-4598 (1991).
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4591-4598
    • Mitts, M.R.1    Bradshaw-Rouse, J.2    Heideman, W.3
  • 27
    • 1842364137 scopus 로고
    • Genetic dissection of Drosaphila adenylate cyclase
    • Livingstone, M. S. Genetic dissection of Drosaphila adenylate cyclase. Proc. Natl Acad. Sci. USA 82, 5992-5996 (1985).
    • (1985) Proc. Natl Acad. Sci. USA , vol.82 , pp. 5992-5996
    • Livingstone, M.S.1
  • 29
    • 0021760534 scopus 로고
    • Sequence, structure and codon preference of the Drosophila ribosomal protein 49 gene
    • O'Connell, P. & Rosbash, M. Sequence, structure and codon preference of the Drosophila ribosomal protein 49 gene. Nucleic Acids Res. 12, 5495-5513 (1984).
    • (1984) Nucleic Acids Res. , vol.12 , pp. 5495-5513
    • O'Connell, P.1    Rosbash, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.