Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain

Genes and Development

Volumn 15, Issue 7, 2001, Pages 859-876

  Zhu, Y ^a   Romero, M I ^a   Ghosh, P ^a   Ye, Z ^a   Charnay, P ^a   Rushing, E J ^a   Marth, J D ^a   Parada, L F ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Animal models; Astrogliosis; Knockouts; Neurofibromatosis; Tumor suppressor

Indexed keywords

SYNAPSIN I;

ANIMAL CELL; ARTICLE; ASTROCYTOSIS; BRAIN CORTEX; BRAIN DEVELOPMENT; CONTROLLED STUDY; EMBRYO; GENE FUNCTION; GENE MUTATION; GLIOSIS; LEARNING DISORDER; MOUSE; NERVE DEGENERATION; NEURAL CREST; NEUROFIBROMATOSIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENIC MOUSE;

ALLELES; ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; GANGLIA, SPINAL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, NEUROFIBROMATOSIS 1; GENES, REPORTER; GENES, SYNTHETIC; GENETIC VECTORS; GLIOSIS; INTEGRASES; LAC OPERON; LEARNING DISORDERS; MAP KINASE SIGNALING SYSTEM; MICE; MICE, KNOCKOUT; MICE, NEUROLOGIC MUTANTS; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEUROFIBROMIN 1; NEURONS; P120 GTPASE ACTIVATING PROTEIN; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS P21(RAS); RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SYNAPSINS; VIRAL PROTEINS;

ANIMALIA; MUS MUSCULUS;

EID: 0035312367     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.862101     Document Type: Article

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