Spatial and temporal patterns of ERK signalling during mouse embryogenesis

Development

Volumn 130, Issue 19, 2003, Pages 4527-4537

  Corson, Laura Beth ^a   Yamanaka, Yojiro ^a   Venus Lai, Ka Man ^a,b,c   Rossant, Janet ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c REGENERON PHARMACEUTICALS INC   (United States)

Author keywords

Embryo; ERK; FGF signaling; MAPK; Mouse

Indexed keywords

CONTIG; ENZYME ANTIBODY; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN TYROSINE KINASE; RAS PROTEIN; RECEPTOR BLOCKING AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; BLOOD VESSEL; BRANCHIAL ARCH; CELL NUCLEUS; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; EAR; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; EYE; FOREBRAIN; GENE TARGETING; HEART; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INCUBATION TIME; INTESTINE; LIMB BUD; LIVER; MESENCEPHALON; MOUSE; NEURAL CREST; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PLACENTA; PRIORITY JOURNAL; PROTEIN DOMAIN; REGULATORY MECHANISM; RHOMBENCEPHALON; SIGNAL TRANSDUCTION; TAIL;

ANIMALS; EMBRYO; EMBRYONIC AND FETAL DEVELOPMENT; EMBRYONIC DEVELOPMENT; EMBRYONIC STRUCTURES; ENZYME ACTIVATION; FEMALE; GESTATIONAL AGE; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOGENESIS; PHOSPHORYLATION; PREGNANCY; RECEPTORS, FIBROBLAST GROWTH FACTOR;

ANIMALIA; MAMMALIA;

EID: 0142074405     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.00669     Document Type: Article

References (63)

1. Alsan, B. H. and Schultheiss, T. M. (2002). Regulation of avian cardiogenesis by Fgf8 signaling. Development 129, 1935-1943.
2. Belcheva, M. M. and Coscia, C. J. (2002). Diversity of G protein-coupled receptor signaling pathways to ERK/MAP kinase. Neurosignals 11, 34-44.
3. Camps, M., Chabert, C., Muda, M., Boschert, U., Gillieron, C. and Arkinstall, S. (1998). Induction of the mitogen-activated protein kinase phosphatase MKP3 by nerve growth factor in differentiating PC12. FEBS Lett. 425, 271-276.
4. Chambers, D., Medhurst, A. D., Walsh, F. S., Price, J. and Mason, I. (2000). Differential display of genes expressed at the midbrain - hindbrain junction identifies sprouty2: an FGF8-inducible member of a family of intracellular FGF antagonists. Mol. Cell Neurosci. 15, 22-35.
5. Christen, B. and Slack, J. M. (1999). Spatial response to fibroblast growth factor signalling in Xenopus embryos. Development 126, 119-125.
6. Ciruna, B. G. and Rossant, J. (1999). Expression of the T-box gene Eomesodermin during early mouse development. Mech. Dev. 81, 199-203.
7. Ciruna, B. G., Schwartz, L., Harpal, K., Yamaguchi, T. P. and Rossant, J. (1997). Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: a role for FGFR1 in morphogenetic movement through the primitive streak. Development 124, 2829-2841.
8. Crowley, C., Spencer, S. D., Nishimura, M. C., Chen, K. S., Pitts-Meek, S., Armanini, M. P., Ling, L. H., MacMahon, S. B., Shelton, D. L., Levinson, A. D. et al. (1994). Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons. Cell 76, 1001-1011.
9. Curran, K. L. and Grainger, R. M. (2000). Expression of activated MAP kinase in Xenopus laevis embryos: evaluating the roles of FGF and other signaling pathways in early induction and patterning. Dev. Biol. 228, 41-56.
10. Deng, C. X., Wynshaw-Boris, A., Shen, M. M., Daugherty, C., Ornitz, D. M. and Leder, P. (1994). Murine FGFR-1 is required for early postimplantation growth and axial organization. Genes Dev. 8, 3045-3057.
11. Dickinson, R. J., Eblaghie, M. C., Keyse, S. M. and Morriss-Kay, G. M. (2002a). Expression of the ERK-specific MAP kinase phosphatase PYST1/MKP3 in mouse embryos during morphogenesis and early organogenesis. Mech. Dev. 113, 193-196.
12. Dickinson, R. J., Williams, D. J., Slack, D. N., Williamson, J., Seternes, O. M. and Keyse, S. M. (2002b). Characterization of a murine gene encoding a developmentally regulated cytoplasmic dual-specificity mitogen-activated protein kinase phosphatase. Biochem. J. 364, 145-155.
13. Elowe, S., Holland, S. J., Kulkarni, S. and Pawson, T. (2001). Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction. Mol. Cell. Biol. 21, 7429-7441.
14. Faber, S. C., Dimanlig, P., Makarenkova, H. P., Shirke, S., Ko, K. and Lang, R. A. (2001). Fgf receptor signaling plays a role in lens induction. Development 128, 4425-4438.
15. Farinas, I., Cano-Jaimez, M., Bellmunt, E. and Soriano, M. (2002). Regulation of neurogenesis by neurotrophins in developing spinal sensory ganglia. Brain Res. Bull. 57, 809-816.
16. Feldmann, P., Eicher, E. N., Leevers, S. J., Hafen, E. and Hughes, D. A. (1999). Control of growth and differentiation by Drosophila RasGAP, a homolog of p120 Ras-GTPase-activating protein. Mol. Cell. Biol. 19, 1928-1937.
17. Fincham, V. J., James, M., Frame, M. C. and Winder, S. J. (2000). Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src. EMBO J. 19, 2911-2923.
18. Furthauer, M., Lin, W., Ang, S. L., Thisse, B. and Thisse, C. (2002). Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signalling. Nat. Cell Biol. 4, 170-174.
19. Gabay, L., Seger, R. and Shilo, B. Z. (1997a). In situ activation pattern of Drosophila EGF receptor pathway during development. Science 277, 1103-1106.
20. Gabay, L., Seger, R. and Shilo, B. Z. (1997b). MAP kinase in situ activation atlas during Drosophila embryogenesis. Development 124, 3535-3541.
21. Goldfarb, M. (1996). Functions of fibroblast growth factors in vertebrate development. Cytokine Growth Factor Rev. 7, 311-325.
22. Hadari, Y. R., Kouhara, H., Lax, I. and Schlessinger, J. (1998). Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation. Mol. Cell. Biol. 18, 3966-3973.
23. Jung, J., Zheng, M., Goldfarb, M. and Zaret, K. S. (1999). Initiation of mammalian liver development from endoderm by fibroblast growth factors. Science 284, 1998-2003.
24. Klemke, R. L., Cai, S., Giannini, A. L., Gallagher, P. J., de Lanerolle, P. and Cheresh, D. A. (1997). Regulation of cell motility by mitogen-activated protein kinase. J. Cell Biol. 137, 481-492.
25. Klock, A. and Herrmann, B. G. (2002). Cloning and expression of the mouse dual-specificity mitogen-activated protein (MAP) kinase phosphatase Mkp3 during mouse embryogenesis. Mech. Dev. 116, 243-247.
26. LaBonne, C., Burke, B. and Whitman, M. (1995). Role of MAP kinase in mesoderm induction and axial patterning during Xenopus development. Development 121, 1475-1486.
27. Lai, K. M. and Pawson, T. (2000). The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryo. Genes Dev. 14, 1132-1145.
28. Lin, W., Furthauer, M., Thisse, B., Thisse, C., Jing, N. and Ang, S. L. (2002). Cloning of the mouse Sef gene and comparative analysis of its expression with Fgf8 and Spry2 during embryogenesis. Mech. Dev. 113, 163-168.
29. Maroon, H., Walshe, J., Mahmood, R., Kiefer, P., Dickson, C. and Mason, I. (2002). Fgf3 and Fgf8 are required together for formation of the otic placode and vesicle. Development 129, 2099-2108.
30. Marshall, C. J. (1995). Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80, 179-185.
31. Martin, G. R. (1998). The roles of FGFs in the early development of vertebrate limbs. Genes Dev. 12, 1571-1586.
32. Minowada, G., Jarvis, L. A., Chi, C. L., Neubuser, A., Sun, X., Hacohen, N., Krasnow, M. A. and Martin, G. R. (1999). Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development 126, 4465-4475.
33. Mohammadi, M., McMahon, G., Sun, L., Tang, C., Hirth, P., Yeh, B. K., Hubbard, S. R. and Schlessinger, J. (1997). Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science 276, 955-960.
34. Murakami, S., Kan, M., McKeehan, W. L. and de Crombrugghe, B. (2000). Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway. Proc. Natl. Acad. Sci. USA 97, 1113-1118.
35. Niswander, L. and Martin, G. R. (1992). Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development 114, 755-768.
36. Niswander, L. and Martin, G. R. (1993). FGF-4 regulates expression of Evx-1 in the developing mouse limb. Development 119, 287-294.
37. Ozaki, K., Kadomoto, R., Asato, K., Tanimura, S., Itoh, N. and Kohno, M. (2001). ERK pathway positively regulates the expression of Sprouty genes. Biochem. Biophys. Res. Commun. 285, 1084-1088.
38. Partanen, J., Schwartz, L. and Rossant, J. (1998). Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos. Genes Dev. 12, 2332-2344.
39. Patel, Y., Kim, H. and Rappolee, D. A. (2000). A role for hepatocyte growth factor during early postimplantation growth of the placental lineage in mice. Biol. Reprod. 62, 904-912.
40. Pearson, G., Robinson, F., Beers Gibson, T., Xu, B. E., Karandikar, M., Berman, K. and Cobb, M. H. (2001). Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr. Rev. 22, 153-183.
41. Pouyssegur, J., Volmat, V. and Lenormand, P. (2002). Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling. Biochem. Pharmacol. 64, 755-763.
42. Reich, A., Sapir, A. and Shilo, B. (1999). Sprouty is a general inhibitor of receptor tyrosine kinase signaling. Development 126, 4139-4147.
43. Reifers, F., Walsh, E. C., Leger, S., Stainier, D. Y. and Brand, M. (2000). Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 (fgf8/acerebellar). Development 127, 225-235.
44. Sawada, A., Shinya, M., Jiang, Y. J., Kawakami, A., Kuroiwa, A. and Takeda, H. (2001). Fgf/MAPK signalling is a crucial positional cue in somite boundary formation. Development 128, 4873-4880.
45. Schlessinger, J. (2000). Cell signaling by receptor tyrosine kinases. Cell 103, 211-225.
46. Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X. F., Breitman, M. L. and Schuh, A. C. (1995). Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376, 62-66.
47. Shapiro, P. S., Vaisberg, E., Hunt, A. J., Tolwinski, N. S., Whalen, A. M., McIntosh, J. R. and Ahn, N. G. (1998). Activation of the MKK/ERK pathway during somatic cell mitosis: direct interactions of active ERK with kinetochores and regulation of the mitotic 3F3/2 phosphoantigen. J. Cell Biol. 142, 1533-1545.
48. Shinya, M., Koshida, S., Sawada, A., Kuroiwa, A. and Takeda, H. (2001). Fgf signalling through MAPK cascade is required for development of the subpallial telencephalon in zebrafish embryos. Development 128, 4153-4164.
49. Sibilia, M. and Wagner, E. F. (1995). Strain-dependent epithelial defects in mice lacking the EGF receptor. Science 269, 234-238.
50. Smeyne, R. J., Klein, R., Schnapp, A., Long, L. K., Bryant, S., Lewin, A., Lira, S. A. and Barbacid, M. (1994). Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene. Nature 368, 246-249.
51. Smith, J. C., Price, B. M., Green, J. B., Weigel, D. and Herrmann, B. G. (1991). Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 67, 79-87.
52. Szebenyi, G. and Fallon, J. F. (1999). Fibroblast growth factors as multifunctional signaling factors. Int. Rev. Cytol. 185, 45-106.
53. Tanaka, S., Kunath, T., Hadjantonakis, A. K., Nagy, A. and Rossant, J. (1998). Promotion of trophoblast stem cell proliferation by FGF4. Science 282, 2072-2075.
54. Tefft, D., Lee, M., Smith, S., Crowe, D. L., Bellusci, S. and Warburton, D. (2002). mSprouty2 inhibits FGF10-activated MAP kinase by differentially binding to upstream target proteins. Am. J. Physiol. Lung. Cell Mol. Physiol. 283, L700-L706.
55. Trumpp, A., Depew, M. J., Rubenstein, J. L., Bishop, J. M. and Martin, G. R. (1999). Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch. Genes Dev. 13, 3136-3148.
56. Uy, G. D., Downs, K. M. and Gardner, R. L. (2002). Inhibition of trophoblast stem cell potential in chorionic ectoderm coincides with occlusion of the ectoplacental cavity in the mouse. Development 129, 3913-3924.
57. Volmat, V., Camps, M., Arkinstall, S., Pouyssegur, J. and Lenormand, P. (2001). The nucleus, a site for signal termination by sequestration and inactivation of p42/p44 MAP kinases. J. Cell Sci. 114, 3433-3443.
58. Wakioka, T., Sasaki, A., Kato, R., Shouda, T., Matsumoto, A., Miyoshi, K., Tsuneoka, M., Komiya, S., Baron, R. and Yoshimura, A. (2001). Spred is a Sprouty-related suppressor of Ras signalling. Nature 412, 647-651.
59. Widmann, C., Gibson, S., Jarpe, M. B. and Johnson, G. L. (1999). Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol. Rev. 79, 143-180.
60. Willard, F. S. and Crouch, M. F. (2001). MEK, ERK, and p90RSK are present on mitotic tubulin in Swiss 3T3 cells: a role for the MAP kinase pathway in regulating mitotic exit. Cell Signal 13, 653-664.
61. Wood, H. B. and Episkopou, V. (1999). Comparative expression of the mouse Sox1, Sox2 and Sox3 genes from pre- gastrulation to early somite stages. Mech. Dev. 86, 197-201.
62. Xu, X., Weinstein, M., Li, C. and Deng, C. (1999). Fibroblast growth factor receptors (FGFRs) and their roles in limb development. Cell Tissue Res. 296, 33-43.
63. Yamaguchi, T. P., Harpal, K., Henkemeyer, M. and Rossant, J. (1994). fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev. 8, 3032-3044.