Haploinsufficiency for the neurofibromatosis 1 (NF1) tumor suppressor results in increased astrocyte proliferation

Oncogene

Volumn 18, Issue 31, 1999, Pages 4450-4459

  Gutmann, David H ^a   Loehr, Allison ^a   Zhang, Yujing ^a   Kim, Joanna ^a   Henkemeyer, Mark ^b   Cashen, Amanda ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Glioma; GTPase activating protein; Neurofibromin; p21 ras; Tumor suppressor gene

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; NEUROFIBROMIN; PROTEIN P21; RAS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOMA; CELL PROLIFERATION; CONTROLLED STUDY; GENE MUTATION; HAPLOIDY; IMMUNOREACTIVITY; MOUSE; NERVE CELL CULTURE; NEUROFIBROMATOSIS; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ANIMALS; ASTROCYTES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIVISION; CELL LINE; COCULTURE TECHNIQUES; ENZYME INHIBITORS; FLAVONOIDS; GENES, NEUROFIBROMATOSIS 1; GLIAL FIBRILLARY ACIDIC PROTEIN; HETEROZYGOTE; HUMANS; MICE; MICE, MUTANT STRAINS; NERVE TISSUE PROTEINS; NEUROFIBROMATOSIS 1; NEUROFIBROMIN 1; NEURONS; PROTEINS;

EID: 0033527061     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202829     Document Type: Article

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