Nebula/DSCR1 Upregulation Delays Neurodegeneration and Protects against APP-Induced Axonal Transport Defects by Restoring Calcineurin and GSK-3β Signaling

PLoS Genetics

Volumn 9, Issue 9, 2013, Pages

  Shaw, Jillian L ^a,b   Chang, Karen T ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CALCINEURIN; DOWN SYNDROME CRITICAL REGION 1 PROTEIN; FASCIDIN II; GLYCOGEN SYNTHASE KINASE 3BETA; KINESIN; MEMBRANE PROTEIN; NEBULA; SYNAPSE RECEPTOR; SYNAPTOTAGMIN; UNCLASSIFIED DRUG;

ALLELE; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; APP GENE; ARTICLE; CANB GENE; CARGO MOTOR INTERACTION; CELL PROTECTION; CONTROLLED STUDY; DOWN SYNDROME; DROSOPHILA; DSCR1 GENE; GENE; GENE FUNCTION; GENE OVEREXPRESSION; MICROTUBULE; MITOCHONDRION; MOTOR ACTIVITY; NEBULA GENE; NERVE DEGENERATION; NERVE FIBER TRANSPORT; NEUROPROTECTION; NONHUMAN; PATHOGENESIS; PHENOTYPE; PROTEIN DNA INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RISK REDUCTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SYNAPSE; SYNAPTOSOME; UPREGULATION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; AXONAL TRANSPORT; AXONS; CALCINEURIN; DOWN SYNDROME; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIA; MUSCLE PROTEINS; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84884680215     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003792     Document Type: Article

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