Mitochondrial superoxide contributes to blood flow and axonal transport deficits in the Tg2576 mouse model of Alzheimer's disease

PLoS ONE

Volumn 5, Issue 5, 2010, Pages

  Massaad, Cynthia A ^a   Amin, Samir K ^a   Hu, Lingyun ^a   Mei, Yuan ^a,b   Klann, Eric ^c   Pautler, Robia G ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b RICE UNIVERSITY   (United States)

^c NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MANGANESE SUPEROXIDE DISMUTASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN MITOCHONDRION; CONTROLLED STUDY; MALE; MITOCHONDRIAL MEMBRANE; MOUSE; NERVE FIBER TRANSPORT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; VASCULAR ENDOTHELIUM;

ALZHEIMER DISEASE; ANIMALS; AXONAL TRANSPORT; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; MICE; MICE, TRANSGENIC; MITOCHONDRIA; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; SUPEROXIDE DISMUTASE; SUPEROXIDES; TAU PROTEINS;

MUS;

EID: 77956553917     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010561     Document Type: Article

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